International Isotope Society Research Articles

Abstracts From the 29th International Isotope Society UK Meeting 17th November 2023.

Abstracts From the 29th International Isotope Society UK Meeting 17th November 2023.

Abstracts of the 28th International Isotope Society (UK group) Symposium: The Synthesis & Applications of Labelled Compounds 2019.

Abstracts of the 28th International Isotope Society (UK group) Symposium: The Synthesis & Applications of Labelled Compounds 2019.

Abstracts of the 27th International Isotope Society (UK group) symposium: Synthesis and applications of labelled compounds 2018

Journal of Labelled Compounds and RadiopharmaceuticalsVolume 63, Issue 7 p. 356-364 ABSTRACTS Abstracts of the 27th International Isotope Society (UK group) symposium: Synthesis and applications of labelled compounds 2018 First published: 15 July 2019 https://doi.org/10.1002/jlcr.3784 Correspondence to: Dr Rebekka Hueting, Wales Research and Diagnostic PET Imaging Centre, Cardiff University, School of Medicine, College of Biomedical and Life Sciences, University Hospital of Wales, Cardiff, CF14 4XN Email: HuetingR@cardiff.ac.uk Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Volume63, Issue715 June 2020Pages 356-364 RelatedInformation

Abstracts of the 26th international isotope society (UK group) symposium: Synthesis & applications of labelled compounds 2017

Abstracts of the 26th international isotope society (<scp>UK</scp> group) symposium: Synthesis &amp; applications of labelled compounds 2017

Abstracts of the 25th International Isotope Society (UK Group) symposium: Synthesis and applications of labelled compounds 2016

Abstracts of the 25^th International Isotope Society (UK Group) symposium: Synthesis and applications of labelled compounds 2016

Abstracts of the 24th international isotope society (UK group) symposium: synthesis and applications of labelled compounds 2015.

The 24th annual symposium of the International Isotope Society's United Kingdom Group took place at the Møller Centre, Churchill College, Cambridge, UK on Friday 6th November 2015. The meeting was attended by 77 delegates from academia and industry, the life sciences, chemical, radiochemical and scientific instrument suppliers. Delegates were welcomed by Dr Ken Lawrie (GlaxoSmithKline, UK, chair of the IIS UK group). The subsequent scientific programme consisted of oral presentations, short 'flash' presentations in association with particular posters and poster presentations. The scientific areas covered included isotopic synthesis, regulatory issues, applications of labelled compounds in imaging, isotopic separation and novel chemistry with potential implications for isotopic synthesis. Both short-lived and long-lived isotopes were represented, as were stable isotopes. The symposium was divided into a morning session chaired by Dr Rebekka Hueting (University of Oxford, UK) and afternoon sessions chaired by Dr Sofia Pascu (University of Bath, UK) and by Dr Alan Dowling (Syngenta, UK). The UK meeting concluded with remarks from Dr Ken Lawrie (GlaxoSmithKline, UK).

Abstracts of the 23rd International Isotope Society (UK group) Symposium: synthesis and applications of labelled compounds 2014

Abstracts of the 23rd International Isotope Society (UK group) Symposium: synthesis and applications of labelled compounds 2014

Abstracts of the 22nd International Isotope Society (UK Group) Symposium: synthesis and applications of labelled compounds 2013

Meeting Summary The 22nd annual symposium of the International Isotope Society's United Kingdom Group took place at the Møller Centre, Churchill College, Cambridge, UK, on Friday, 18 October 2013. The meeting was attended by 65 delegates from academia and industry; the life sciences; and chemical, radiochemical and scientific instrument suppliers. Delegates were welcomed by Dr Ken Lawrie (GlaxoSmithKline, UK, chair of the IIS UK group). The subsequent scientific programme consisted of oral and poster presentations on isotopic chemistry and applications of labelled compounds, or of chemistry with potential implications for isotopic synthesis. Both short-lived and long-lived isotopes were represented, as were stable isotopes. The symposium programme was divided into a morning session chaired by Dr Karl Cable (GlaxoSmithKline, UK) and afternoon sessions chaired by Mr Mike Chappelle (Quotient Biosciences, UK) and by Dr Nick Bushby (AstraZeneca, UK). The UK meeting concluded with remarks from Dr Ken Lawrie (GlaxoSmithKline, UK).

Abstracts of the 21st International Isotope Society (UK group) symposium: synthesis and applications of labelled compounds 2012

Meeting SummaryThe 21st annual symposium of the International Isotope Society's United Kingdom Group took place at the Møller Centre, Churchill College, Cambridge, UK, on Friday 12th October 2012. The meeting was attended by around 60 delegates from academia and industry, the life sciences, chemical, radiochemical and scientific instrument suppliers.Delegates were welcomed by Dr Ken Lawrie (GlaxoSmithKline, UK, chair of the IIS UK group). The subsequent scientific programme consisted of oral and poster presentations on isotopic chemistry and applications of labelled compounds or of chemistry with potential implications for isotopic synthesis. Both short‐lived and long‐lived isotopes were represented, as were stable isotopes. The symposium programme was divided into a morning session chaired by Professor Chris Willis (University of Bristol, UK) and afternoon sessions chaired by Mr Mike Chappelle (Quotient Biosciences, UK) and by Dr Sofia Pascu (University of Bath, UK). The UK meeting concluded with remarks from Dr Ken Lawrie (GlaxoSmithKline, Stevenage, UK). image

Abstracts of the 20th International Isotope Society (UK group) Symposium: Synthesis &amp; Applications of Labelled Compounds 2011

Meeting SummaryThe 20th annual symposium of the International Isotope Society's United Kingdom Group took place at the Wellcome Genome Campus, Hinxton, Cambridge, UK on Tuesday 18 October 2011. The meeting was attended by around 70 delegates from academia and industry, the life sciences, chemical, radiochemical and scientific instrument suppliers.Delegates were welcomed by Dr Ken Lawrie (GlaxoSmithKline, UK, chair of the IIS UK group). The subsequent scientific programme consisted of oral and poster presentations on isotopic chemistry and applications of labelled compounds or of chemistry with potential implications for isotopic synthesis. Both short‐lived and long‐lived isotopes were represented, as were stable isotopes. The symposium programme was divided into a morning session chaired by Prof. Chris Willis (University of Bristol, UK) and afternoon sessions chaired by Mr Mike Chappelle (Quotient Biosciences, UK) and by Dr Nick Bushby (AstraZeneca, UK). The UK meeting concluded with remarks from Dr Ken Lawrie (GlaxoSmithKline, Stevenage, UK).

19th international isotope society (UK group) symposium: synthesis &amp; applications of labelled compounds 2010

The 19th annual symposium of the International Isotope Society's United Kingdom Group took place at the Wellcome Genome Campus, Hinxton, Cambridge, UK on Thursday 14th October 2010. The meeting was attended by around 80 delegates from academia and industry, the life sciences, chemical, radiochemical and scientific instrument suppliers. Delegates were welcomed by Dr. Ken Lawrie (GlaxoSmithKline, UK, chair of the IIS UK group). The subsequent scientific programme consisted of oral and poster presentations on isotopic chemistry and applications of labelled compounds, or of chemistry with potential implications for isotopic synthesis. Both short-lived and long-lived isotopes were represented, as were stable isotopes. The symposium programme was divided into a morning and an afternoon session chaired by Prof. Chris Willis (University of Bristol, UK) and Dr. Nigel Botting (University of St Andrews, UK) respectively. In addition, a short presentation on the formation of Special Interest Groups within the International Isotope Society was given by Dr. George Ellames (Covance, UK), who asked members with particular isotopic interests to contact him (george.ellames@covance.com) if they would like to be involved in forming or participating in these groups. The UK meeting concluded with remarks from Dr. Ken Lawrie (GlaxoSmithKline, Stevenage, UK). This year's UK symposium had an excellent level of sponsorship, and the symposium should prove self-financing. The location and facilities of the Hinxton campus again proved very popular and the next IIS UK symposium is provisionally planned for 18th October 2011 at the same venue.

17th workshop of the international isotope society - central european division. The synthesis and applications of isotopes and isotopically labelled compounds

17th workshop of the international isotope society - central european division. The synthesis and applications of isotopes and isotopically labelled compounds

Abstracts of the 18th international isotope society (UK group) symposium: synthesis &amp; applications of labelled compounds 2009

Abstracts of the 18th international isotope society (UK group) symposium: synthesis &amp; applications of labelled compounds 2009

16th workshop of the international isotope society–central european division. The synthesis and applications of isotopes and isotopically labelled compounds

16th workshop of the international isotope society–central european division. The synthesis and applications of isotopes and isotopically labelled compounds

Abstracts of the 17th International Isotope Society (UK group) Symposium Synthesis and Applications of Labelled Compounds 2008

Abstracts of the 17th International Isotope Society (UK group) Symposium Synthesis and Applications of Labelled Compounds 2008

14th Workshop of the Central European Division e.V. of the International Isotope Society

14th Workshop of the Central European Division e.V. of the International Isotope Society

The history of the International Isotope Society

AbstractThe author traces back to the late nineteen fifties the history of events preceding the current activities of the International Isotope Society (IIS) founded in 1986. The obvious conclusions are that there was a need for regular scientific meetings focused on topics such as the synthesis of isotopes, isotopically labelled and their applications. The various existing chemical and technical societies could not cover in their meetings such topics as efficiently as the IIS did. The Kansas City 1982 and 1985 first two unofficial meetings lead to the formation of the IIS in 1986 and then to a series of other regular symposia as 1988 (Innsbruck, Austria), 1991 (Toronto, Canada), 1994 (Strasbourg, France), 1997 (Philadelphia, USA), 2000 (Dresden, Germany), 2003 (Boston, USA), 2006 (Edinburgh, United Kingdom) and then in 2009 (Chicago, USA). The IIS also carries out its activities in yearly local Chapter meetings in the US, UK, Central Europe, Romania, Russia and China. At the same time, according to its Mission stated in the IIS Constitution (available in the www.intl.isotope‐soc.org website) the IIS also encourages the continuation of the independent meetings called the International Conferences of Isotopes; the activities of an international Low Level Waste IIS committee; the publication of the IIS Newsletter and maintenance of its website); organizing various workshops and short courses; and last but not least gives its support to the Journal of Labeled Compounds and Radiopharmaceutical by contributing papers and pro‐bono work on the Editorial as well as on the Advisory Board of the Journal. Copyright © 2007 John Wiley &amp; Sons, Ltd.

13th Workshop of the Central European Division e.V. of the International Isotope Society

I. E. Marko [Universite catholique de Louvain, Belgium]—Novel Orthoesters in Organic Synthesis. S. J. Harwood [GlaxoSmithKline, UK]—The Synthesis of Stable Labelled Ketamine. Th. Moenius, R. Salter, B. Wietfeld, P. Burtscher, C. Zueger [Novartis, Switzerland]—C-13, C-14, N-15 Labelling of the 4-Cyanobenzyl bromide – A Versatile Labelling Building Block. J. Clayden [University of Manchester, UK]—Synthesis and Stereocontrol with Lithiated Amides. R. Salter, K. Bordeaux, P. Burtscher, Y. Metz, Th. Moenius, I. Rodriguez, R. Ruetsch, R. Voges, C. Zueger [Novartis, Switzerland]—Isotopic Labelling of STI571 and its Metabolites in the Development of Gleevec®. J. M. Gardiner, W. Stimpson, N. Panchal [University of Manchester, UK], J. Herbert, G. J. Ellames [Sanofi-Aventis, UK]—Synthesis of Labelled Carbohydrates. M. Beller [Rostock University, Germany]—Homogeneous Catalysis – A Powerful Tool for the Synthesis of Pharmaceuticals. J. Kozempel, J. Kadeřavek, L. Lesetický, O. Lebeda [University of Prague, Czech]—Preparation of Ortho-radiohalogenated Phenylazides and Triazenes, Versatile Building Blocks for Indirect Labelling. K. Wahala, P. Kiuru, E. Leppala, M. Pohjoispaa, K. Parikka, B. Raffaelli [University of Helsinki, Finland]—Controlled Polydeuteration of Estrogenic Compounds. J. M. Herbert [Sanofi-Aventis, UK]—Catalyst Stability in Iridium-mediated Isotope Exchange. C. G. M. Janssen, W.L.M. Verluyten, M. Vliegen [Johnson & Johnson Pharmaceutical, Belgium]—Pd/C Catalysed Hydrogenolytic H/T Exchange in Solvents, Effects on Solvents and Product in a Bromine-tritium Exchange Reaction. P. Mading, F. Fuchtner, R. Bergmann, J. Pietzsch, C. Hultsch, F. Wust [Forschungszentrum Rossendorf, Germany]—A New Module-Assisted Synthesis of the Versatile, Bifunctional Labelling Agent [18F]SFB: From Radiochemistry to Applications. M. Scheunemann, J. Vercouillie, St. Fischer, J. Steinbach [Institut fur Interdisziplinare Isotopenforschung Leipzig, Germany], D. Sorger, U. Grosmann, O. Sabri, R. Schliebs [University Leipzig, Germany]—Syntheses and First Biological Evaluation of 18F Labelled Bicyclic Analogues of Vesamicol as Potential VAChT Imaging Agents.

Synthesis of [15N3]2-amino-7-methyl-1,8-naphthyridine†

†Revised version of a paper presented at the 12th Workshop of the International Isotope Society, Central European Division, June 17–18, 2004, Bad Soden, Germany.

14th International Isotope Society (UK group) symposium

AbstractMeeting ProgrammeProf David O'Hagan [University of St Andrews, UK]—Enzymatic C–18F Bond Synthesis: A New Strategy for PET Synthesis.Dr Michael Carroll [University of Newcastle, UK]—Studies Towards 6‐[18F]Fluoro‐m‐tyramine using Iodonium Salts.Dr John Gardiner [University of Manchester, UK]—Methods Towards Isotopomer‐Versatile Synthesis of 13C‐Labelled Carbohydrates.Prof William Lockley [University of Surrey, UK]—Some New Catalytic Systems for Isotope‐Exchange Labelling.Dr David Rustidge [Scynexis Europe, UK]—14C‐Synthesis—Not Always as Easy as it Looks.Dr Richard Hartley [University of Glasgow, UK]—The Potential for using Titanium Alkylidene Chemistry in Solid‐Phase Radiochemical Synthesis.Dr Ian Wilson [Turku Imanet, Finland]—Transition of PET Tracers from Clinical Research Tools to Commercial Diagnostics.Dr Simon Harwood [GlaxoSmithKline, UK]—The Synthesis of Stable Labelled Ketamine.Dr John Herbert [Sanofi‐Aventis, UK]—Towards Robust Conditions for Iridium‐mediated Exchange.Dr Conor Barry [University of Bristol, UK]—Total Synthesis of Clavosolide A.