As of today, foreign trade agreements are an important vehicle for development and promotion of human rights. This effect can be achieved by including in the text of such an agreement a human rights clause, a special provision which contains a number of international human rights standards, compliance with which must be guaranteed by the contracting States. The article focuses on a specific example of these agreements, namely the Political, Free Trade and Strategic Partnership Agreement between the United Kingdom of Great Britain and Northern Ireland. To that end, the article first examines the general development and the importance of bilateral trade between States, as this, in turn, affects its potential in the human rights, humanitarian and security areas. Then the authors outline specific provisions of the Agreement in the context of the topic of the article and analyzes the possible consequences of their implementation, namely due to the aggression of the Russian Federation against Ukraine. The role and significance of the established monitoring bodies and the mechanism for responding to human rights clause violations have been studied separately. The article contains elements of a combinatorial approach, as the analysis of the Political, Free Trade and Strategic Partnership Agreement is carried out, where possible, through comparisons with the Association Agreement between Ukraine and the European Union. Thus, the authors trie to find out which of the two agreements has the greatest potential for the development of the human rights system in Ukraine.