Health Organization International Research Articles

Female Genital Mutilation (FGM) in Indonesia: Systematic Review

Introduction: Indonesia is the third largest country that carries out female circumcision. As many as 51.2% of girls aged 0-11 years have undergone female circumcision. Female Genital Mutilation (FGM) or female circumcision is a dangerous traditional practice that still occurs in Indonesia, which has caused pros and cons among the community even though, based on scientific studies, female circumcision has been proven to have no health benefits. Female circumcision has even been banned by law and opposed by international health organizations. Objective: The study aims to identify factors influencing female circumcision in Indonesia, focusing on the Social Determinant and Health theory. Method: This study is a systematic review that collects several studies according to the PRISMA guidelines. Using relevant keywords, studies were obtained from various databases, such as Garuda, Google Scholar, and Semantic Scholar. Studies were collected from June to July 2024. Result: From 2.254 articles found, ten articles were selected for further analysis. Factors such as maternal age, maternal education, knowledge, culture/tradition, beliefs, family support, and sources of information also influence the practice of circumcision in female children. Conclusion: Female circumcision is a dangerous traditional practice that is still carried out today due to the culture and beliefs of the local community, which are still strong and believe that female circumcision must be carried out on their daughters.

Integrating Reproductive Health and Nutrition: A Breakthrough Solution to Combat Stunting

Objective: This study aims to explore the importance of integrating reproductive health and nutrition as a strategic approach in addressing stunting in Indonesia. Materials & Methods: Using a qualitative study, this research analyzed findings from observation and from various scientific journals, reports of international and national health organizations, and policies related to stunting, reproductive health, and nutrition. The study emphasizes the importance of comprehensive perinatal interventions and supports the strengthening of maternal and child health systems. Findings: The analysis shows that a comprehensive approach that integrates nutrition interventions and reproductive health initiatives can significantly reduce the prevalence of stunting. This approach highlights the importance of adequate nutritional supplementation, quality perinatal health care, and health education programs for expectant mothers. Conclusion: The findings of this study are expected to contribute to the development of health policies that aim to sustainably reduce stunting rates with a holistic approach that focuses on maternal and child health.

Systematic review of ethics and legislation of a Global Patient co-Owned Cloud (GPOC)

Background The use of cloud-based storage for personal health records (PHRs) has significantly increased globally over the past thirty years. The four recently published GPOC Series articles introduced the concept of a Global Patient co-Owned Cloud (GPOC) for personal health records. The series includes a systematic review and meta-analysis, a summit, a sandbox, and a survey, with 100% participation from UN member states and key international health organisations. GPOC aims to establish patient co-ownership of PHRs, addressing integration and access challenges. Methods This study is built upon the published GPOC systematic review and meta-analysis that focused on examining cloud-based personal health records and elements such as data security, efficiency, performance, privacy and cost-based factors. However, this study selectively reviews the ethical, legislative and potential human rights dimensions of GPOC. Thus, it includes ethical aspects of co-ownership, rights, privacy, policies, and AI integration. The original study was PROSPERO registered with CRD42022342597, which serves as the foundation for the current study. Results This study offers a comprehensive global overview of ethics, legislation and initiatives by states and organisations. We analyse AI integration and future challenges for GPOC implementation. We present principles from ‘Ethics by Design’ and the ‘Principles of Biomedical Ethics’ by Beauchamp and Childress alongside the European General Data Protection Regulation (GDPR). The study presents a global overview of the relevant global latticework of legislation. Conclusions This study suggests that GPOC could potentially establish a new human right to patient co-ownership of personal health information. GPOC aims to facilitate global AI integration in healthcare and address existing challenges in PHR integration. A decentralised GPOC, supported by blockchain consensus, may offer benefits such as enhanced data security, interoperability, and equitable access to healthcare information globally. Thus, GPOC may have a positive impact on global health.

Reckless subjects, future capital? ‘Youth’ as an object of concern in international health organizations’ discourse

ABSTRACT Contemporary international organizations (IOs) are routinely portrayed as being more accessible to a wide variety of actors than ever before. The recent hyper-institutionalization of youth in international politics testifies to this pluralization, at least quantitatively. This paper traces the historical emergence of youth as an object of concern among health IOs. Covering a period of over 50 years, we analyse semantic fields surrounding youth and find that young people have primarily been portrayed as society’s future capital in development discourses or as a risk-prone group in the context of HIV/AIDS and reproductive health. Only since the beginning of the 21st century can we trace portrayals of youth that emphasize rights, inclusion and engagement in global health. Our study addresses an empirical research gap on youth in global health and prompts us to critically re-evaluate the optimistic liberal assessments that have marked International Relations (IR) theories on the ‘opening-up’ of IOs.

Achilles Pain, Stiffness, and Muscle Power Deficits: Midportion Achilles Tendinopathy Revision – 2024

The Academy of Orthopaedic Physical Therapy (AOPT) has an ongoing effort to create evidence-based clinical practice guidelines (CPG) for orthopaedic physical therapy management of patients with musculoskeletal impairments described in the World Health Organization's International Classification of Functioning, Disability, and Health (ICF). The 2024 Achilles Pain, Stiffness, and Muscle Power Deficit: Midportion Achilles Tendinopathy Clinical Practice Guideline (CPG) is a revision of the 2018 CPG and represents the third CPG from AOPT on this topic. The goals of the revision were to provide a concise summary of the contemporary evidence and to develop new recommendations or revise previously published recommendations to support evidence-based practice. This current CPG covers prevalence, pathoanatomical features, risk factors, clinical course, diagnosis, examination, imaging and physical therapy interventions for the management of midportion Achilles tendinopathy.

Assessing nursing students’ e[formula omitted]health literacy and foresights to global health challenges during COVID[formula omitted]19 restrictions: A cross-sectional study with a machine learning approach

AimThis study aims to assess the e-health literacy and foresights to global health challenges of nursing students during the COVID19 restrictions. BackgroundAs the healthcare environment becomes more digitalized, understanding how nursing students perceive and prepare for global health challenges during the COVID19 restrictions and e-health literacy is crucial for customizing educational strategies to enhance their capabilities. DesignA descriptive and correlational study design was employed. MethodsThe study included 310 nursing students from six universities in Istanbul, Turkey, encompassing both state and foundation institutions. Data were collected via online surveys, including an Information Form, a Foresight Form for Global Health Challenges and an E−Health Literacy Scale. The study extended beyond conventional statistical analysis by incorporating a tree-based ML model, specifically a Random Forest classifier, to identify complex patterns and relationships affecting e−health literacy and global health perceptions. ResultsThe analysis indicated that e−health literacy levels among nursing students are significantly shaped by their academic year, participation in global health courses and engagement with international health organizations. ML techniques pinpointed the ability to discern high−quality online health resources as a pivotal skill, emphasizing the need for nursing curricula to focus on advanced critical evaluation skills. ConclusionsThe findings stress the necessity of integrating critical evaluation and information−seeking skills into nursing education to equip students for the complexities of a globalized health landscape.

Yellow fever breakthrough infections after yellow fever vaccination: a systematic review and meta-analysis

Yellow fever vaccination is considered to provide effective long-term immunity. However, yellow fever breakthrough infections in vaccinated patients have been reported. In this systematic review and meta-analysis we aimed to identify and summarise all documented symptomatic yellow fever breakthrough infections in the literature occurring less than 10years and 10years or more after primary yellow fever vaccination. We searched MEDLINE (Ovid), Embase (Ovid), and Global Index Medicus for records published between Jan1, 1936 (introduction of yellow fever vaccination) and June 16, 2023. We included prospective and retrospective cohort studies, case series and reports, and epidemiological reports from national and international health organisations reporting symptomatic yellow fever among individuals vaccinated 30days or more before symptom onset. Weexcluded cases vaccinated less than 30days before symptom onset. The primary outcome for the meta-analysis was the proportions of vaccinees among virologically confirmed and probable cases of yellow fever (IgMseroconversion without seroconversion to other flaviviruses). Risk of bias was assessed with an adapted version of the Newcastle-Ottawa Scale. Records of moderate or good quality (probable or confirmed yellow fever diagnosis with documented proof of previous vaccination) were included for random-effects meta-analysis. Thissystematic review and meta-analysis is registered with PROSPERO, number CRD42023450205. After reviewing 1975records, 37records reported a total of 6951yellow fever cases, of which 537were vaccinated. 31records were of low quality. Nine confirmed and 24probable cases with proof of previous yellow fever vaccination were identified, all from Brazil. Confirmed cases were vaccinated 3months to 3years before symptom onset; of these patients two fell severely ill and died. The pooled proportion of verified yellow fever breakthrough infections among probable and confirmed cases was 3% (95% CI 1-19%). No confirmed yellow fever breakthrough infections were identified occurring 10years or more after yellow fever vaccination. Yellow fever breakthrough infections documented in literature are rare, and not necessarily more common 10years or more after primary yellow fever vaccination. This finding suggests that a single dose of yellow fever vaccination is sufficient to provide lifelong protective immunity against symptomatic yellow fever. None.

Strengthening public health professionals in policymaking in the Eastern WHO European region

Abstract Background The collaborative research between EUPHA and WHO aimed to explore factors impacting public health professionals’ (PHP) involvement in health policy processes in the Eastern WHO European Region, addressing barriers, enablers, and capacity-building needs. Methods Utilizing a mixed methodology, the study employed document analysis, scoping review, and interviews to triangulate data, with the document analysis focusing on 4 published Essential Public Health Operations Self-Assessment Reports, the scoping review analysing 15 key articles, and 5 semi-structured interviews providing additional insight from key country stakeholders. Results Core findings revealed significant barriers impeding PHPs' participation in policy processes. Among others, these included limited intersectoral collaboration, shortage of skilled public health (PH) personnel, financial resource constraints and inadequate governance structures. Conversely, several enablers were identified, such as a positive trend in increased intersectoral collaboration and innovative governance structures during Covid-19, the development of more trained PHPs and the utilization of International Health Organisations. The two main capacity building needs reported were the importance of modernizing PH education and promoting intersectoral collaboration. Conclusions This study offers a preliminary overview of how PHPs' involvement in health policy processes in these countries can be enhanced: More intersectoral collaboration, updated PH education curricula and trainings, and governance re-design building on positive trends seen during the pandemic. Following actions are recommended: Creation of an international platform for cross-sectoral PH communication & exchange, direct support for universities and PH researchers, development of comprehensive PH trainings, assistance in forming or strengthening national public health associations and identification & sharing of effective local governance practices. Key messages • This research identifies barriers to PHPs’ participation in Eastern WHO European Region's health policy processes, while highlighting enablers like increased collaboration during Covid-19 to build on. • Recommendations to harness the enablers include clear actions such as creating an international public health platform for interaction and exchange or build-up of national public health associations.

Prevalence, Mortality, and Associated Anomalies in Esophageal Atresia: A Retrospective Study of Finnish Population Data (2004-2017).

The aim of the study was to investigate the prevalence of esophageal atresia (EA), frequency of associated anomalies, and mortality from 2004 to 2017 in the Finnish population. We hypothesized the Spitz classification and the presence of other congenital malformations would predict mortality in patients with EA as well as assumed the survival to be high among patients with EA. This retrospective, population-based study was based on the registries maintained by THL Finnish Institute for Health and Welfare and Statistics Finland. The cases were identified and classified according to the World Health Organization's International Classification of Diseases and Health Related Problems (ICD) revisions 9 and 10 (ICD-9 and ICD-10) codes and accompanying written diagnoses. Associated anomalies were classified based on the EUROCAT criteria, and minor anomalies were excluded. All statistical tests were performed as a two-sided significance level set at p < 0.05. The chi-square or Fisher's exact test was utilized for categorical variables. The change in prevalence rates during the study period was evaluated with linear regression. In total, 337 cases with EA were identified including 295 (87.5%) live births, 17 (5.0%) stillbirths, and 25 (7.4%) terminations of pregnancy. The total prevalence for EA in Finland was 4.17/10,000 births with no significant change during the study period, p = 0.35. Neonatal mortality was 5% (n = 15) and 1-year survival was 91.5%. Mortality was associated with syndromic cases (p = 0.002). The Spitz classification predicted neonatal mortality better than cardiac anomalies alone (p < 0.001 and p = 0.6, respectively). Type C was the most common atresia type (65.9%) followed by type A (14.8%) and B (6.8%). The most common group of associated malformations were heart defects (35.0%) followed by other gastrointestinal tract malformations (15.3%) and limb anomalies (12.2%). Syndromic cases (12.2%) were associated with type A and B atresias (p = 0.001). VACTERL association was observed in 16.6% of the cases. The overall prevalence of EA remains stable and relatively high in Finland. Despite the high prevalence of co-occurring malformations, the overall survival rate is high. Spitz classification predicted neonatal survival well.

The amended international health regulations: Implications and challenges for domestic legal frameworks.

The World Health Organisation's International Health Regulations were amended in May 2024, with a number of implications for countries to amend their legal and institutional frameworks. This perspective highlights two key areas of focus in the amendments-the importance of multisectoral coordination and subnational work - and explores their links to health security challenges and to concrete country experiences. National legal and institutional frameworks constitute a key enabling mechanism for effective public health systems capable of preventing, detecting, and responding promptly to public health events and emergencies, and the recent IHR amendments provide a new impetus for WHO Member States to make these changes.

Access to dental services and use of toothpaste with optimal fluoride content in Peruvian children

BackgroundLeading international health organizations advise using toothpaste that contains at least 1,000 parts per million of fluoride, emphasizing that this practice should begin with the eruption of the first primary tooth.AimTo determine the association between access to dental services and the use of toothpaste with 1,000 ppm fluoride or more in Peruvian children under twelve years of age.Materials and methodsA cross-sectional analysis was conducted using data from the 2021 Demographic and Family Health Survey. The main variable studied was the use of toothpaste containing a fluoride concentration of 1,000 ppm or more. Additionally, the access to dental care, the time elapsed since the last dental visit, and the type of healthcare facility were analyzed. Multilevel regression was applied to examine the relationship between variables and the dependent variable, with Peru's 24 regions serving as the analytical level.ResultsAccording to the bivariate analysis, the natural region, area of residence, place of residence, wealth index, and age were associated with the use of fluoride toothpaste with 1,000 ppm or more. In the multilevel analysis, the access to dental services was not associated with the use of fluoride toothpaste with 1,000 ppm or more (p = 0.454); similarly, the time elapsed since the last dental visit also showed no association (p = 0.676), as did the type of healthcare facility (p = 0.752, p = 0.896, p = 0.983).ConclusionAccessing dental services, the time elapsed since the last dentist visit, and the location where that care was received were not associated with the use of toothpaste containing 1,000 ppm or more of fluoride among Peruvian children during the year 2021.

Is e-cigarette advertising associated with e-cigarette use among young people? New survey evidence from Poland.

Young people are routinely exposed to e-cigarettes advertising. We examined the impact of e-cigarette advertising on e-cigarette use in a large representative sample of adolescents. Data came from cross-sectional sample of the nationwide study on the health effects of tobacco products called PolNicoYouth, which included adolescents aged 15-18 years (N = 7,498). Data were collected through a detailed questionnaire recommended by international health organizations for monitoring tobacco use by adolescents. Simple and multiple logistic regression analyzes were conducted, adjusting for sex, age, type of school, place of residence, smoking of traditional cigarettes and parental smoking. Frequencies and proportions for descriptive statistics, and adjusted odds ratios with 95% confidence intervals for logistic regression models were reported. Approximately, 56% of interviewees had noticed some form of e-cigarettes advertising. Exposure to e-cigarette advertising was significantly associated with ever use of e-cigarettes (OR = 1.29; 95% CI: 1.09-1.53). Exposure to e-cigarette advertising via club/pub/disco was significantly associated with current e-cigarette use (OR = 1.58; 95% CI: 1.06-2.36). Adolescents who have ever used e-cigarettes were more likely than never users to report exposure to advertisements on club/pub/disco (OR = 1.57; 95% CI: 1.08-2.30) and internet (OR = 1.22; 95% CI: 1.01-1.47). Despite the applicable advertising restrictions, the majority of young people declared contact with e-cigarette advertising, which shows the urgent need for more global action. The internet and advertisements in clubs, pubs and discos seem to be the key places of exposure. These forms of exposure need to be urgently addressed given their clear link to e-cigarette use.

Verification of five-factor models and reference scores for personality dysfunction and trait domains of the Personality Assessment Questionnaire for ICD-11 (PAQ-11), revised version.

A brief self-reported measure of the Personality Assessment Questionnaire for the 11th edition of the World Health Organization's International Classification of Disease (ICD-11) (PAQ-11) was developed to evaluate ICD-11 personality traits. The aim of this study was to investigate the validity of the revised PAQ-11 version (PAQ-11R) with an additional item in the Dissociality domain and thresholds for the severity of personality dysfunction and domains. Study 1 examined the construct validity of the PAQ-11R in 192 university students in Korea. Study 2 estimated tentative reference scores of personality dysfunction and domains of the PAQ-11R in 91 patients in Korea. In study 1, the PAQ-11R had a five-factor structure and the revised Dissociality scale had better convergent and discriminant validities than the previous version. In study 2, the receiver operating characteristic (ROC) curve of the PAQ-11R identified a threshold score of 35. Reference scores for domains were estimated as 15 for Negative Affectivity, 10 for Detachment, 8 for Anankastia, and 5 each for Disinhibition and Dissociality. These scores contribute to severity of personality disturbance but remain qualifiers only; they are not diagnostic. The results suggest that the PAQ-11R is useful as a quick assessment tool for identifying the domains of personality dysfunction in clinical practice in harmony with the ICD-11 guidelines.

Economic Feasibility Study For The Setting Up And Utilization Of A Multipurpose Food Irradiation Facility In Jigawa State, North-West Nigeria

One proven and efficient method for processing and preserving food is food irradiation. Irradiation is a productive and economical technique that has several advantages over other technologies used in food processing. The technique helps prevent food loss and ensure food safety by getting rid of parasites and bacteria that can make people sick or even kill them. Produce from agriculture and animal food products can benefit from radiation treatment to increase shelf life while maintaining microbiological safety and quality. Based on more than 50 years of research and testing data, a number of national and international food and health organizations have acknowledged and supported the safety of food and products treated to ionizing radiation. The purpose of this study was to evaluate the economic feasibility for the establishment and utilization of a multipurpose food irradiation facility in Jigawa state and its environ as a post-harvest treatment for major arable crops cultivated in the state and its environ which include millet, sorghum, groundnut, sesame, rice, maize, tomatoes, pepper, onions, wheat, and dried fish. The study explored ways in which irradiation may be employed for each crops and vegetable with the approved dose rate. The cost of irradiation was also calculated for different sources of colbalt-60. The study results indicate one or more technically economically feasible application points for irradiation in the processing of each commodity considered. The most promising points are the potential for disinfestation of large quantity of crops and vegetables which will ensure food availability all year round and at a cheap rate for citizens as well as the potential for export thereby helping to grow the revenue and GDP of the state.

Tantangan dan Solusi Terkini dalam Penanganan Penyakit Menular

Infectious disease management continues to face various dynamic challenges along with environmental changes, human travel patterns, and the emergence of new pathogens. This study aims to analyze and identify current challenges and the solution in infectious disease management through a literature review method. The review covered scientific literature from various relevant sources, including journals, books, and reports from international health organizations. The results of this study show that the main challenges include antimicrobial resistance, and lack of health infrastructure in some regions. In addition, global issues such as climate change and urbanization exacerbate the situation by increasing the risk of disease spread. The study also found that international collaboration, innovations in medical technology, and increased public awareness and education are key to overcoming these challenges. In conclusion, addressing infectious diseases requires a multidisciplinary and cross-sectoral approach to improve the global response to evolving health threats.

Building health systems resilience: understanding the social, economic, and cultural impacts of climate change from stakeholders' perspectives in Indonesia

sObjectivesThis study explores stakeholders' perspectives on the direct, social, economic, and cultural impacts of climate change on health in Indonesia and identifies possible strategies to enhance health system resilience.MethodsThis study followed the Consolidated Criteria for Reporting Qualitative Research (COREQ) guidelines to ensure comprehensive and transparent reporting. Purposive sampling was used to select 22 stakeholders with relevant expertise, including government officials, representatives from international and professional health organizations, health workers, and community representatives. Semi-structured interviews were conducted, and data were analyzed using directed content analysis. Data saturation was reached when no new themes emerged.ResultsThe findings reveal significant challenges to Indonesia's health system due to climate change. Community awareness varies widely, with higher levels in disaster-prone areas. Socially, climate change has fostered community cooperation through collective adaptation efforts but has also led to tensions due to inequitable resource distribution. Economically, rising healthcare costs and financial instability, particularly in rural and disaster-prone regions, place a strain on the system. Culturally, there is a growing emphasis on environmental conservation, promoting eco-friendly practices and the integration of traditional and modern health approaches.ConclusionBuilding health system resilience in Indonesia requires addressing the social, economic, and cultural impacts of climate change. Possible strategies include enhancing public health education, strengthening healthcare infrastructure, improving inter-agency coordination, and leveraging technology to support effective responses to climate-related health threats, ultimately promoting national health, social stability, and economic growth.

Salmonella pathogenesis-based In-silico design and immunoinformatic analysis of multi-epitope vaccine constructs in broiler veterinary medicine

Salmonellosis, a zoonotic gastrointestinal disease, presents a significant global health burden with a high incidence rate. Transmission primarily occurs through the consumption of contaminated poultry products, although water and contact with asymptomatic animals are also vectors. The disease’s pervasiveness has prompted international health organizations to advocate for robust prevention and control strategies. This study focuses on the in-silico design of a multi-epitope vaccine targeting Salmonella enterica serovar Typhimurium’s fimH protein, a fimbriae component crucial for bacterial adhesion and pathogenicity. The vaccine construct was developed by identifying and synthesizing non-allergenic, antigenic, and non-toxic epitopes for both Cytotoxic T Lymphocytes and Helper T Lymphocytes. Adjuvants were incorporated to enhance immunogenicity, and the vaccine’s structure was modeled using advanced bioinformatics tools. The proposed vaccine demonstrated promising antigenicity and immunogenicity profiles, with a favorable physical-chemical property analysis. The vaccine’s structures, designed by computational analysis, suggests high likelihood to native protein configurations. Antigenicity and allergenicity assessments validate the vaccine’s immunogenic potential and hypoallergenic nature. Physicochemical evaluations indicate favorable stability and solubility profiles, essential for vaccine efficacy. This comprehensive approach to vaccine design expressed in Chlorella vulgaris holds promises for effective salmonellosis control. The multi-epitope vaccine, designed through meticulous in-silico methods, emerges as a promising candidate for controlling salmonellosis. Its strategic construction based on the fimH protein epitopes offers a targeted approach to elicit a robust immune response, potentially curbing the spread of this disease in poultry.

Developmental screening of neurodevelopmental disorders before age 6: a nationwide health screening program.

We aimed to investigate the association between developmental screening before 24 months of age and neurodevelopmental disorders (NDDs) at 4-6 years of age. We included 922,899 newborn born between 2014 and 2016 registered in National Health Insurance Service (NHIS). Developmental screening was administered at 9-12 and 18-24 months old with the Korean Developmental Screening Test for Infants & Children (K-DST). Diagnoses of NDDs was based on the World Health Organization's International Classification of Diseases, Tenth Revision (ICD-10), provided by the NHIS database. Among 637,277 individuals who underwent screening at 9-12 and 18-24 months, Screen-positivity (defined as summed score < -2 standard deviation) for gross motor domain at 9-12 months was significantly associated with the incidence of autism spectrum disorder (aHR, 2.24; 95% CI, 1.80-2.80) and cerebral palsy (aHR, 4.81; 95% CI, 3.62-6.38). Screening positive at language domain at 18-24 months old was associated with autism spectrum disorder (aHR 5.50; 95% CI, 4.31- 7.02) and developmental language disorder (aHR 8.67; 95% CI, 7.27-10.33) at 4-6 years of age. Widespread nationwide implementation of screening programs before 24 months was effective in identifying NDDs at 4-6 years of age. Further strategies integrating with referral and intervention systems should be established. We investigated the screening effect of nationwide developmental screening program on neurodevelopmental disorders using nationwide data. Gross motor delay during infancy was significant predictor of later neurodevelopmental disorders. Language, cognitive, and social delay before 24 months of age was associated with later autism spectrum disorders and developmental language disorders. Widespread nationwide implementation of screening programs before 24 months was effective in identifying NDDs at 4-6 years of age and should be encouraged.

Molecular characterization of peste des petits ruminants virus and Mycoplasma capricolum subsp. capripneumoniae in small ruminants in northern Mauritania, 2023.

Global eradication of peste des petits ruminants (PPR) is planned for 2030 by international animal health organizations in collaboration with national partners. As the deadline approaches, it is fundamental that the PPR status in each country is determined. In addition, the identification of other pathogens of small ruminants that share common geographical locations and can produce similar clinical signs is also important for differential diagnosis. With this in mind, 37 samples collected from goats and sheep presenting respiratory symptoms in Mauritania in 2023 were screened for the presence of PPR virus, Capripoxvirus, Pasteurella multocida and Mycoplasma capricolum subspecies capripneumoniae (Mccp) using a one-step multiplex RT-qPCR assay. None of the samples were positive for Capripoxvirus or P. multocida. Nine of them were positive for PPRV and sequence analysis of a segment of the PPRV nucleoprotein revealed that they belonged to lineage IV and were similar to viruses recently identified in Côte D'Ivoire, Guinea, and Niger indicating transboundary movement. The full genome of one representative virus was also generated. Mccp was identified in eight samples and multi-locus sequence analysis (MLSA) identified them as belonging to MLSA Group 3 together with Mccps identified in China, Tajikistan, Turkey and the United Arab Emirates. This is the first time that such a study has been undertaken in Mauritania and the data generated should be of interest to those involved in the management of goat diseases in Mauritania and neighbouring countries.

Malaria Prevention and Control in Nigeria: Evaluating the Effectiveness of Current Strategies

Malaria has been a significant public health challenge in Nigeria, contributing to high morbidity and mortality rates, particularly among children under five and pregnant women. Despite all efforts made to control and prevent malaria, Nigeria continued to bear a disproportionate share of the global malaria burden. This review critically evaluated the effectiveness of current malaria prevention and control strategies in Nigeria, including the use of insecticide-treated nets (ITNs), indoor residual spraying (IRS), chemoprevention, and public health education campaigns. The methodology involved a comprehensive analysis of peer-reviewed studies, government reports, and data from international health organizations to assess these strategies. The review identified gaps in the implementation of these strategies and explored innovative approaches that could enhance their impact. It also discussed the role of environmental management, community engagement, and the integration of technology in malaria control efforts. The findings suggested that while existing strategies have made significant progress in reducing malaria transmission, challenges such as resistance to insecticides, inconsistent use of preventive measures, and limited healthcare infrastructure hindered their overall effectiveness. The review concluded by proposing recommendations for strengthening malaria prevention and control efforts in Nigeria, with a focus on sustainability, scalability, and community involvement. Keywords: Malaria Control, Insecticide-Treated Nets (ITNs), Indoor Residual Spraying (IRS), Chemoprevention, Environmental Management.