Introduction: Cardiovascular diseases of ischemic origin are associated with inadequate nutrition and excess adiposity. The aim of this study was to determine the dietary and anthropometric profile of patients with acute coronary syndrome (ACS). Methods: Cross-sectional study with patients ≥ 18 years and ACS admitted in a tertiary hospital in South of Brazil. Socio-demographic, clinical, anthropometric (weight, height, waist and hip circumferences) data and information regarding physical activity were evaluated; a food frequency questionnaire (FFQ) was used to identify the dietary intake. Comparisons between the nutrients’ intake obtained by dietary survey and those recommended by the national and international guidelines were carried out using the Student t-test for one mean. Results: A total of 104 patients were evaluated, with a mean age of 60.6 ± 11.3 years and 59.6% were man. The prevalence of obesity according to body mass index (BMI) was 32.7%, and 58.6% of the patients presented a very high waist circumference. In relation to diet, the amounts of energy (kcal/kg of body weight), protein (in %), saturated fat (in %) and sodium (in mg) were higher than the recommended by guidelines (p <0.004), and potassium, calcium, magnesium (in mg) and fiber (in g) intake were lower than that recommended (p values <0.001). Conclusion: The prevalence of obesity was high in patients with ACS and the intake of most of the evaluated nutrients was not in accordance with the recommendations of national and international guidelines.