Internal Decompression Research Articles

Minimally Destabilizing Corridor for Resection of Dumbbell Nerve Sheath Tumors: A Novel Surgical Technique.

Current surgical strategies for dumbbell nerve sheath tumors (DNSTs) with cord compression have primarily involved wide spinal exposures with total laminectomy and unilateral facetectomy, often leading to spinal destabilization and requiring fusion, or staged procedures separately addressing the intraspinal and extraforaminal tumor components. This study highlights technical nuances of a novel approach for DNST resection to minimize spinal destabilization and avoid fusion while facilitating safe, single-stage complete resection. A retrospective chart review was conducted on patients undergoing DNST resection. Using unilateral subperiosteal dissection, hemilaminotomy and medial facetectomy procedures are performed. The extradural tumor component is resected, followed by internal decompression of the intradural tumor. A small horizontal incision at the origin of the nerve root sleeve releases the underlying dural stricture, facilitating delivery of the remaining intradural tumor and allowing section of the nerve root of origin. Ultrasonography confirms complete tumor resection and return of cord pulsation, and excludes intradural hemorrhagic complications. The dura is reconstructed using a dural substitute bolstered with fat graft and sealant. Twelve consecutive patients undergoing this approach from 2014 to 2021 were included. Mean patient age was 53.5 years, and 58.3% were male. Nine tumors were cervical and 3 were lumbar. Five patients presented with myelopathy, 4 with radiculopathy, and 4 with axial pain. Two cases had transient intraoperative neuromonitoring signal changes. Eleven tumors were diagnosed as schwannomas and 1 as neurofibroma. All patients had complete resection of the intraspinal component; 2 had far distal extraforaminal residual. No patient has had recurrence, progression of residual, or signs of spinal instability during follow-up (median 28.5 months, range 6-66 months). This study highlights technical considerations for DNST resection, focusing the approach at the center of the tumor, with minimal bone removal and ligamentous disruption. Intraoperative ultrasound is instrumental in the safety of this approach.

Transconjunctival internal decompression of the orbit in patients with endocrine ophthalmopathy: a retrospective analysis

BACKGROUND: The most characteristic manifestation of endocrine ophthalmopathy (EO) is the proptosis development in a patient. It is possible to correct the displacement of eyeballs by performing an orbital decompression surgery.
 AIM: To evaluate the clinical efficacy of treating patients with endocrine proptosis using transconjunctival internal decompression of the orbit.
 MATERIALS AND METHODS: The study included 86 orbits of 43 patients with bilateral proptosis. All patients underwent MSCT examination, proptosis was detected due to an increase in the soft tissue component. Transconjunctival decompression of both eye sockets was performed according to the described method, and the amount of eyeball displacement after surgery was investigated.
 RESULTS: Patients complaints about constant pressure behind the eye, observed in 39 patients, disappeared during the first day after surgery in 21 patients, in the remaining patients they gradually disappeared within a week. In 32 patients with preoperative diplopia after surgery, in 27 it completely disappeared, in the remaining 5 it remained in the extreme positions. 6 months after surgery, a decrease in proptosis amount from 21.1 1.5 mm to 20.6 1.5 mm was noted, visual acuity was 1.0 0.02, decreased visual acuity remained in 3 cases due to the incipient cataract, IOP decreased from 20 1.2 mm Hg to 19 1.3 mm Hg. There were no eyeball movement restrictions at the control examination.
 CONCLUSIONS: Internal (soft tissue) decompression of the orbit is an effective method for proptosis correction exophthalmos in patients with lipid EO form. Carrying out the decompression surgery through the conjunctival access allows to constantly monitor the shape and size of the pupil in the operated orbit, to conduct controlled hemostasis of the orbital tissues. The use of preliminary calculations of the volume of soft tissues to be removed (according to MSCT) makes it possible to obtain a predictable effect of the surgery in variable degrees of proptosis. Transconjunctival decompression helps avoiding cicatricial processes of the eyelid skin.

Endoscopic Contralateral Interhemispheric Transfalcine Keyhole Approach for Large Falcine Meningiomas

Falcine meningioma is usually approached ipsilaterally, and the technique for tumor removal has traditionally been performed under microscopy. We report a surgical procedure for large falcine meningioma by an endoscopic contralateral interhemispheric transfalcine keyhole approach. The study period was from September 2019 to March 2021. Study participants were patients with World Health Organization grade I meningioma showing falx attachment, excluding neurofibromatosis, who underwent initial surgery at our institution. The surgical procedure begins with a small contralateral craniotomy of about 3cm, followed by insertion of an endoscope. The tumor attachment to the falx is excised, exposing the tumor. Internal decompression is performed, and the lesion is dissected from the surrounding brain before removal through the falx. An endoscopic contralateral interhemispheric transfalcine keyhole approach was used to resect 4 cases of large falcine meningioma. The mean operation time was 265minutes (range: 216-294minutes), achieving Simpson grade I removal in all cases. No evidence of cerebral infarction, cerebral edema, or new neurological complaints related to impaired venous return was seen using this surgical method. In the case of falcine meningioma, the endoscopic keyhole contralateral technique allows detachment of the tumor from the falx and safe manipulation in a minor field of view. In addition, because the craniotomy is smaller and the operation time is shorter, this procedure offers a less-invasive approach for the patient. This technique is thus, in our opinion, quite advantageous.

Integrated Analysis of Expression Profile and Potential Pathogenic Mechanism of Temporal Lobe Epilepsy With Hippocampal Sclerosis.

ObjectiveTo investigate the potential pathogenic mechanism of temporal lobe epilepsy with hippocampal sclerosis (TLE+HS) by analyzing the expression profiles of microRNA/ mRNA/ lncRNA/ DNA methylation in brain tissues.MethodsBrain tissues of six patients with TLE+HS and nine of normal temporal or parietal cortices (NTP) of patients undergoing internal decompression for traumatic brain injury (TBI) were collected. The total RNA was dephosphorylated, labeled, and hybridized to the Agilent Human miRNA Microarray, Release 19.0, 8 × 60K. The cDNA was labeled and hybridized to the Agilent LncRNA+mRNA Human Gene Expression Microarray V3.0,4 × 180K. For methylation detection, the DNA was labeled and hybridized to the Illumina 450K Infinium Methylation BeadChip. The raw data was extracted from hybridized images using Agilent Feature Extraction, and quantile normalization was performed using the Agilent GeneSpring. P-value < 0.05 and absolute fold change >2 were considered the threshold of differential expression data. Data analyses were performed using R and Bioconductor. BrainSpan database was used to screen for signatures that were not differentially expressed in normal human hippocampus and cortex (data from BrainSpan), but differentially expressed in TLE+HS’ hippocampus and NTP’ cortex (data from our cohort). The strategy “Guilt by association” was used to predict the prospective roles of each important hub mRNA, miRNA, or lncRNA.ResultsA significantly negative correlation (r < −0.5) was found between 116 pairs of microRNA/mRNA, differentially expressed in six patients with TLE+HS and nine of NTP. We examined this regulation network’s intersection with target gene prediction results and built a lncRNA-microRNA-Gene regulatory network with structural, and functional significance. Meanwhile, we found that the disorder of FGFR3, hsa-miR-486-5p, and lnc-KCNH5-1 plays a key vital role in developing TLE+HS.

How to Use a High-Speed Drill and an Ultrasonic Aspirator During Skull Base Surgery

During surgery for skull base lesions, maximum efforts should be made to improve the removal rate of the lesion while avoiding complications, and it is necessary to expand the surgical field by selecting appropriate surgical instruments and equipment. In both microsurgery and endoscopic surgery, high-speed drills and ultrasonic aspirators contribute significantly to the safe and reliable removal of skull base lesions, and the surgeons need to be familiar with these characteristics. The specific vital points are as follows: (1) Preparation of the appropriate environment for using a high-speed drill or an ultrasonic aspirator with the understanding of the microsurgical anatomy, (2) Bone excision using a high-speed drill with the selection of an appropriate drill attachment or drill bar tip according to the site of use, (3) Internal decompression of lesions using an ultrasonic aspirator with appropriate settings, (4) Additional expansion of the surgical field by using an ultrasonic aspirator in the osteotomy mode, and so on. This section describes details of how to use a high-speed drill and an ultrasonic aspirator during skull base surgery.

Paroxysmal sympathetic hyperactivity following acute diffuse brain swelling due to traumatic brain injury: a case report with good clinical outcome

BackgroundParoxysmal sympathetic hyperactivity (PSH) may occur after acquired brain injury. The clinical presentation of PSH results from increased sympathetic overdrive, including transient paroxysms of tachycardia, hypertension, hyperventilation, hyperthermia, dystonic posturing, and excessive sweating. The exact pathophysiology of PSH, however, remains unclear, and no definitive treatment is available. Herein, the authors report a case of PSH in a male patient who experienced acute brain swelling after acquired head injury, for which a good clinical outcome was achieved due to multimodal treatment. The ensuing discussion also addresses the pathophysiology of PSH.Case presentationAn 18-year-old man was transported to the authors’ hospital after experiencing a traumatic brain injury. On admission, computed tomography revealed cerebral herniation due to diffuse brain edema in the left parietal lobe. Emergency decompressive craniotomy and internal decompression were performed. After surgery, anti-edema therapy (glycerol and mannitol) was continued. Ten days postoperatively, PSH was diagnosed in accordance with the PSH assessment score (20 points). Vecuronium, fentanyl, morphine, propofol, dexmedetomidine, and a calcium channel blocker were administered; however, the drug effect was insufficient. Thirty-two days postsurgery, the patient gradually recovered from the adrenergic symptoms of PSH, and head computed tomography performed 32 days after surgery revealed improvement in diffuse brain edema. Ultimately, the patient fully recovered and lived independently at home.ConclusionsConsidering the pathophysiology of PSH, cerebral contusion, acute brain swelling, and secondary mechanisms of brain injury may trigger sympathetic nerve-enhancing regions and cause hyperexcitation of the sympathetic nervous system, resulting in PSH. The outcome of the present case demonstrates that PSH can be reversed if it is identified early and before it becomes irreversible, that is, post the development of hypoxic encephalopathy or widespread brain damage. Appropriate management, including decompression craniotomy for brain swelling and multidisciplinary treatment, leads to good clinical outcomes.

Lateral Transtumoral Transforaminal Removal of Cervical Dumbbell Tumors

Abstract Background Cervical dumbbell tumors constitute 15% of cervical nerve sheath tumors. These tumors occupy intraspinal, foraminal, and extraspinal compartments. Laminectomy, laminectomy and facetectomy and anterolateral partial vertebrectomy are the approaches used to address these multicompartment tumors. Laminectomy leads to incomplete tumor removal. Other approaches ensure complete tumor excision but involve more extensive bone work. Objective We describe our surgical technique and clinical experiences of six patients treated through single lateral approach, addressing all compartments (transforaminal approach) with minimal or no bony resection. Methods Six patients with cervical dumbbell tumors underwent minimally invasive transforaminal approach and tumor excision. The cohort consisted of four women and two men. All patients underwent complete tumor excision Technique Intraoperative X-ray and ultrasound are used to localize the respective foramen. Skin is entered from the lateral side and sequential dilatation is done through muscles. The dilators and port are docked to the lateral surface of articular facets. Standard technique of capsule dissection, internal decompression and capsule mobilization is done to remove the tumor. Arachnoid is seen at the end. Tumor cavity is obliterated with fat graft. Results Total excision of tumor was documented in all patients with postoperative MRI scan. The mean blood loss was 100 mL. The patients could be discharged on second or third postoperative day. Mean follow-up is of 48 months (18–70 months) and all patients had resolution in features of myelopathy. Conclusions Endoportal transforaminal approach is technically feasible and minimally invasive option to remove the dumbbell schwannomas.

Minimally Neural Retractive, Total Annular Resection, Transforaminal Endoscopic (TARTE) Approach for Severely Canal Compromising Lumbar Disk Herniation Accompanied by a Neurologic Deficit.

Treatment of severely canal compromising lumbar disk herniations (LDH), occupying more than 50% of the canal area, are associated with technical difficulty and worse outcomes. This study aimed to describe new techniques of transforaminal endoscopic lumbar diskectomy (TELD) with less neural retraction, and total annular resection for broad-based severely canal compromising disk herniation. We also evaluated the feasibility and safety of the techniques, and analyzed the clinical and radiologic outcomes of 32 patients presenting with neurologic deficits. A retrospective cohort study was performed with 32 consecutive patients who underwent TELD for broad-based severely canal compromising LDH between January 2018 and January 2020. We removed the LDH using two novel techniques: (1) the "mobile outside-in" approach and total annular resection method and (2) internal decompression and subsequent pushdown method of the migrated fragment. The cross-sectional area (CSA) on magnetic resonance image was evaluated preoperatively and compared with the postoperative image within 7 days and between 6 months and 1 year. The visual analog scale (VAS) for back and leg pain, Oswestry disability index (ODI), MacNab's criteria, and motor power of the involved lower extremities were evaluated pre- and postoperatively. A total of 32 patients, with an average age of 37.5 years (range: 17-66), underwent surgery. The mean VAS score for back pain improved from 7.84 ± 1.02 to 1.31 ± 0.54 and the ODI score improved from 74.3 ± 7.82 to 20.4 ± 3.71 at final follow-up. According to MacNab's criteria, 23 patients had excellent and 9 patients had good outcomes at final follow-up. All patients operated on at the L4-L5 level had great toe/ankle dorsiflexion and/or ankle plantar flexion weakness; knee extension weakness was found at the L2-L3 and L3-L4 levels. Motor function improved significantly; the mean values and range preoperatively, and at 1 month, 3 months, and final follow-up, were 3.41 ± 0.95 (1-4), 4.56 ± 0.56 (3-5), 4.88 ± 0.34 (4-5), and 4.97 ± 0.18 (4-5), respectively (p < 0.001, at all follow-up). The mean values and range of the preserved CSA proportion, preoperatively and within 1 week after surgery, and at final follow-up were 34.9 ± 10.9 (15-61), 81.06 ± 10.24 (63-97), and 93.03 ± 5.37 (76-99), respectively (p < 0.001, at all follow-up). The transforaminal endoscopic approach for broad-based severely canal compromising LDH can be considered a feasible surgical option for an experienced surgeon. With total annular resection and pushdown of migrated fragments, safe and complete removal of LDH was possible in patients with a neurologic deficit. Total annular resection may increase the overall but not the early recurrence rate.

CS-5 A case of anaplastic pleomorphic xanthoastrocytoma in the pineal region

Tumors in the pineal gland are rare tumors that account for about 0.3% of all brain tumors and have various histological types of tumors develop with germinoma, pineocytoma, and pineoblastoma in that order. On the other hand, pleomorphic xanthoastrocytoma (PXA) is a rare tumor of less than 0.2% and frequently occurs in supratentorial cerebral surface of children and young adults.A case was a 61-year-old man whose pineal tumor was found due to visual disturbance. MRI showed a 23 mm-sized lesion with cysts and inhomogeneous enhancement in the pineal gland. Partial calcification was observed, but there was no non-communicating hydrocephalus, and no increase in HCG-β and AFP with blood sampling. A midline suboccipital craniotomy was performed in the sitting position, a head-up surgery was performed using a 4K / 3D video microscope system (ORBEYE exoscope, Olympus) by the infratentorial supracerebellar approach (ITSCA). The bridging veins and precentral cerebellar vein were dissected to expose the posterior surface of the tumor, and internal decompression was performed. For the complication of air embolism, artificial cerebrospinal fluid was sprayed, and the bilateral internal jugular veins were compressed to confirm the inflow point. There was strong adhesion to the Rt vein of Rosenthal, and the site was removed intracapsularly. Finally, subtotal resection was performed with remaining the upper part of the tumor, a blind lesion behind the Vein of Galen. Vertical gaze palsy occurred after this operation, but it gradually improved over time. Tumor showed pathologically remarkable polymorphism, poor microvascular proliferation and necrosis, but mitotic figures 4–5 / 10HPF, MIB-1 index 10%, GFAP positive, no BRAF V600E mutation. There are few reports of PXA occurring in the pineal gland, and this case is the sixth case. It is also the first report for pineal tumors using ORBEYE through ITSCA in the sitting position.

Retractorless brain surgery: technical considerations

BackgroundRetraction is necessary to access deep areas in the brain and skull base, but prolonged and forceful use of fixed retraction might be injurious. Several techniques were developed, in the concept of minimally invasive neurosurgery, to eliminate or minimize the use of fixed retractors. The authors discuss the technical considerations and limits in applying dynamic retraction in brain surgery for a variety of lesions using different approaches.ResultsWe retrospectively collected 123 cases with brain lesions in diverse locations, were dynamic retraction, using the tools in the operator hands and was achieved successfully instead of fixed retraction. Cases with aneurysms were excluded, although retraction was applied during clipping only. Superficial and large masses that do not require fixed retraction as a routine were excluded also. We relied mainly on patient positioning to benefit from the gravity, proper design of the craniotomy, arachnoid dissection, cerebrospinal fluid aspiration, and internal decompression of the mass when possible.Different approaches for different lesions were utilized in our patients, subfrontal or pterional and their modifications in 45.5% of cases, suboccipital in 21.1%, retrosigmoid in 13%, the interhemispheric approach in 10.5%, transcortical to lateral ventricles in 7.3%, and posterior subtemporal in 2.4%.Dynamic retraction with the surgical tools was used successfully in all cases except 7 patients (5.6%) where we had to use fixed retraction transiently.ConclusionSeveral considerations are helpful and amenable to achieve successful brain surgery without fixed retraction. Utilizing the gravity, unlocking of the brain, choosing the surgical corridor, cerebrospinal fluid suctioning, and mastering of the microsurgical techniques are the keys.

Hearing preservation/rehabilitation surgery for small vestibular schwannoma: preliminary experience with the presigmoid retrolabyrinthine approach

Background The presigmoid retrolabyrinthine approach (PRA) for small vestibular schwannoma (VS) has unique advantages. Combination with partial labyrinthectomy further makes up its defect of high demand for anatomy. Objective Aimed to describe our use of the PRA with partial labyrinthectomy in VS surgery. Methods We retrospectively analyzed 10 patients diagnosed with VS who underwent PRA between September 2017 and November 2020. Their perioperative data were analyzed. Results Six tumors were on the left and three were on the right. One case was due to neurofibromatosis type 2 with bilateral involvement and underwent internal auditory canal decompression by PRA without tumor removal; all other patients underwent total tumor resection. Four patients underwent cochlear implantation simultaneously because of hearing loss that was detected during surgery. Three patients underwent partial labyrinthectomy. Five patients achieved hearing preservation, and one experienced hearing improvement. One of the three patients who underwent partial labyrinthectomy maintained hearing. All patients’ pre- and postoperative facial nerve functions were House-Brackmann grade I. After a median follow-up time of 13 months, no tumors recurred. Conclusions PRA for small VS is a safe and effective surgery that can achieve facial nerve and hearing preservation. Combination with partial labyrinthectomy can also preserve hearing.

Efficacy of computed tomography-assisted limited decompression in the surgical management of thoracolumbar fractures with neurological deficit

ObjectiveTo investigate the effect of CT-assisted limited decompression in managing single segment A3 lumbar burst fracture.MethodA retrospective study (January 2015–June, 2019). One hundred six cases with single-level Magerl type A3 lumbar burst fractures treated with short-segment posterior internal fixation and limited decompression. Patients were divided into two groups: CT-assisted group and non-CT-assisted group. Perioperative factors, clinical outcomes, post-operative complications, imaging parameters, and health-related quality of life (HRQoL) were evaluated.ResultsKyphosis, loss of anterior and posterior vertebral body heights, operative time, and post-operative complications were not significantly different between the two groups. The visual analog score (VAS) and spinal canal encroachment in the CT-assisted group were lower compared with the non-CT-assisted group (p < 0.05). The Japanese Orthopaedic Association (JOA) score, the simplified HRQoL scale, and the American Spinal Injury Association (ASIA) Spinal Cord Injury Grade in the CT-assisted group were significantly higher compared with the non-CT-assisted group (p < 0.05).ConclusionCT-assisted limited decompression in the treatment of single-segment A3 lumbar burst fracture can achieve better fracture reduction and surgical results and improve the long-term recovery of the patients’ neurological function and quality of life.

Effect of decompression range on decompression limit of cervical laminoplasty.

BackgroundsCervical posterior decompression surgery is used to relieve ventral compression indirectly by incorporating a backward shift of the spinal cord, and this indirect decompression is bound to be limited. This study aimed to determine the decompression limit of posterior surgery and the effect of the decompression range.MethodsWe retrospectively reviewed the data of 129 patients who underwent cervical open-door laminoplasty through 2008 to 2012 and were grouped as follows: C4–C7 (n = 11), C3–C6 (n = 61), C3–C7 (n = 32), and C2–C7 (n = 25). According to the relative location of spinal levels within a decompression range, the type of decompression at a given level was categorized as external decompression (ED; achieved at the levels located immediately external to the decompression range margin), internal decompression (ID; achieved at the levels located immediately internal to the decompression range margin), and central decompression (CD; achieved at the levels located in the center, far from the decompression range margin). The vertebral–cord distance (VCD) was used to evaluate the decompression limit. The C2–C7 angle and VCD on post-operative magnetic resonance images were analyzed and compared between groups. The relationship between VCD and decompression type was analyzed. Moreover, the relationship between the magnitude of the ventral compressive factor and the probability of post-operative residual compression at each level for different decompression ranges was studied.ResultsThere was no significant kyphosis in cervical curvature (> −5°), and there was no significant difference among the groups (F = 2.091, P = 0.105). The VCD of a specific level depended on the decompression type of the level and followed this pattern: ED < ID < CD (P < 0.05). The decompression type of a level was sometimes affected by the decompression range. For a given magnitude of the ventral compressive factor, the probability of residual compression was lower for the group with the larger VCD at this level.ConclusionsOur study suggests that the decompression range affected the decompression limit by changing the decompression type of a particular level. For a given cervical spinal level, the decompression limit significantly varied with decompression type as follows: ED < ID < CD. CD provided maximal decompression limit for a given level. A reasonable range of decompression could be determined based on the relationship between the magnitude of the ventral compressive factor and the decompression limits achieved by different decompression ranges.

New Method of Calculating the Excess Amount of Soft Tissues of the Orbit in Patients with Endocrine Ophthalmopathy when Planning Operations

Objective. Improving the efficiency of the operation of orbit decompression in patients with endocrine ophthalmopathy through the development of a new method for calculating an excess volume of soft tissues of the orbit. Patients and methods . A total of 16 patients with edematous exophthalmos were examined, 7 of them were men and 9 women were aged 28 to 62 years (mean age 39 ± 8 years). All patients underwent surgery — simultaneous internal decompression of the orbit for bilateral exophthalmos with endocrine ophthalmopathy (EO). Before surgery and after 6 months. after surgery, patients were performed MSCT control. According to the method developed by us with the help of standard software MSCT, before the operation, calculations were made and the magnitude of the postoperative standing of the eyeballs was planned. Results . As a result of the operations performed, we removed the estimated amount of adipose tissue and achieved the predicted result. Error in the calculations amounted to 0,1( + /-0,1) mm, which may be due to inaccurate labeling during planning. Findings . The developed calculation method makes it possible to calculate the planned volume of the removed fatty tissue before the operation with the minimum error, without using complex mathematical calculations and without resorting to the help of additional equipment and software.

CS-06 A CASE OF GLIOBLASTOMA METASTATIC TO THE LUMBAR VERTEBRA

BACKGROUNDMost cases of glioblastoma recur within one year even under the standard treatment of surgical resection, radiation therapy and chemotherapy. 60–70% of recurrences are local, and in rare cases of metastasis, most are within the CNS. Extradural metastasis is considered exceedingly rare.CASE REPORTWe present a 21-year-old man post total resection of right parietal lobe glioblastoma, diagnosed with lumber metastasis. He originally presented with impaired consciousness and left hemiplegia at the age of 20 and underwent gross total resection of the tumor. Pathology was IDH wild type, H3F3A K34R/V wild-type glioblastoma. Radiotherapy and adjuvant temozolomide per the Stupp regimen as well as infusion of bevacizumab were conducted. 6 months after the resection of tumor, the patient presented with severe back pain. Radiographic studies showed an osteolytic mass on the first lumbar vertebrae, and needle biopsy was consistent with glioblastoma. Posterior spinal fusion, internal decompression and radiotherapy were conducted to relieve the pain. At 3 months after the diagnosis of lumbar metastasis, he is currently treated with temozolomide and bevacizumab, without the enlarging of the tumor.DISCUSSIONAs far as we investigated, there has been 30 cases of vertebral metastasis of glioblastoma reported in literature. Considering the biological obstacles that prevent glioblastomas from infiltrating outside of the CNS, it can be speculated that deposition of tumor cells into the blood stream or excision of the dura due to surgical interventions may attribute to extracranial metastasis. Due to the improvement of overall survival of glioblastoma, vertebral metastasis is suspected to be more common. Therefore, investigation of its risk factors and standardization of its treatment is necessary.CONCLUSIONWe reported a case of lumbar metastasis of glioblastoma. Extradural metastasis of glioblastoma must be included in differential diagnoses in treating patients with glioblastoma.

Minimally Invasive Endoscopic Keyhole Approach for Meningiomas

Abstract INTRODUCTION The advantages of neuroendoscopic surgery are wide viewing angle and freedom of axis of view with minimal surgical trauma. Taking advantage of the features of neuroendoscopy, the authors report the experience of minimally invasive endoscopic keyhole approach (EKA) for various meningiomas. METHODS A total of 28 cases of various type of meningiomas were treated by EKA from 2007 to 2018. A keyhole of about 2.5 cm was created according to the case, and tumor removal was performed using an endoscope and exoscope. The scope was held by a pneumatic holder controlled by the assistant to continue the procedure in a comfortable environment. RESULTS EKAs were performed for anterior skullbase lesions via eyebrow skin incision (n = 12), posterior fossa lesions including tentorial meningiomas, torcular meningiomas (n = 7), falcine lesions (n = 6), subtemporal approach (n = 2), enplaque convexity menigiomas (n = 1). All the tumors were resected as planned with minimum brain retraction and well-illuminated fine vision in deep corner. In the cases of a large tumor in the elderly, maximum internal decompression was performed, and the adhered tumor was left on the surface of the brain to avoid injury. The brain retraction was automatically limited by the small craniotomy, and excellent magnified image in deep corner was obtained by EKA. By eliminating the blind spots, radical resection is achieved. Also, in the aging society, depending on the patient with benign meningioma, it is important to consider what better treatment is, to alleviate symptoms and to coexist with the tumor. The cooperation of the assistant is important for this approach. To avoid the interference between the endoscope and the instrument, it is necessary to have a technique for moving the endoscope as needed in order to keep the fine visual field. CONCLUSION In the treatment of meningioma, the role of endoscopes is important in both the radicality obtained in a wide field of view and the less invasiveness in the aging society.

Application of standard decompressive craniectomy in the treatment of traumatic brain injury

Traumatic craniocerebral injury has been paid close attention by neurosurgeons at home and abroad due to its high morbidity and mortality. Cerebral contusion and intracranial hematoma caused by various injury mechanisms are the main causes of increased intracranial pressure in the acute stage of traumatic brain injury. As a classic surgical method, standard decompressive craniotomy, often together with intracranial hematoma evacuation, brain debridement and internal decompression, has become the main surgical treatment in the acute stage of traumatic brain injury, saving the lives of many patients with severe cerebral injury, the importance of this procedure is irreplaceable. In long-term clinical practice, through the unremitting efforts of first-line neurosurgeons and neuroscientists, a large number of studies have been conducted on the relationship between the details, norms and prognosis of craniotomy, so as to better regulate the treatment of traumatic brain injury and reduce the death and disability rate of patients with severe brain injury. This article systematically reviews and analyzes the pathophysiological mechanism of intracranial hypertension and the mechanism, development history, surgical methods, indications and contraindications, prognosis and prospects of the intracranial hypertension. Through this article, the author hope to have some guidance and suggestions for future clinical work. Key words: Craniocerebral trauma; Intracranial pressure; Decompressive craniectomy

Unedited microneurosurgery of a falcotentorial meningioma

Background:Falcotentorial meningiomas are pineal region meningiomas that arise from the dura of the tentorium cerebelli and posterior part of the falx. These tumors are commonly supplied by branches of the internal carotid artery such as the meningohypophyseal trunk, inferolateral trunk, and anterior choroidal artery. Less frequently, branches of the ophthalmic artery, vertebral artery, or external carotid artery are also involved. Based on neuroimaging studies, falcotentorial meningiomas may be classified as anterior, superior, inferior, and posterior types. Here, we present an unedited microsurgical resection of a superior falcotentorial meningioma.Case Description:The patient with a meningioma of the posterior inferior falx and a minimal extension to the tentorium underwent sitting praying position and a right occipital interhemispheric approach. Strong retraction of the dura followed a superior sagittal sinus based opening. Careful microsurgical access between the medial surface of the occipital lobe and the falx toward the splenium of corpus callosum allowed us to recognize the lesion. Thus, a cottonoid placed over the cerebral surface avoiding direct contact with the bipolar forceps, and the constant separation of the falx cerebri with the aspiration tube along the access developed a proper surgical route preventing any cortical lesion. Along the approach, cerebrospinal fluid was continuously released from the pericallosal cistern as well. Once well recognized the meningioma, we proceeded with the internal decompression of the lesion using a thumb regulated suction tube and bipolar forceps. Tissue samples from the tumor were taken for the histological diagnosis, and under conventional microsurgical technique, the meningioma was completely removed by piecemeal technique. A small lateral tear on the falx required hemostatic reparation with Tachosil. Water dissection provided us a clear cleavage plane for the microsurgical dissection of the tumor and maintained a clean operative field along the procedure. Occipital arteries running over the lateral surface of the meningioma were carefully dissected and isolated from the lesion, while the deep venous system did not achieve any contact with the tumor. After the ipsilateral component of the meningioma was resected, we intent are dissecting the contralateral segments of the tumor with a curved dissector. At the last stage of the surgery, small incision at a tumor-free segment of the falx allowed us to remove the falcotentorial attachment of the lesion. Under high microscopic magnification, the remaining minimal portion of meningioma extending under the tentorium was coagulated. After complete microsurgical removal of the meningioma, careful homeostasis based on electrocoagulation surgical and Tachosil was achieved. Finally, we performed a surgical wound closure under standard technique.Conclusion:This unedited video offers all detailed aspects for an efficient and safe falcotentorial meningioma microneurosurgery.Videolink:http://surgicalneurologyint.com/videogallery/pineal-meningioma.

Non-Medication-Based Apparatus for the Treatment of Lumbospinal Dorsopathy

A means for non-medication-based treatment of spinal dorsopathy is described, specifically, using mechano-therapeutic DRX systems. The use of local internal disk-root decompression in 327 patients with lumbosacral dorsopathy, including 82.9% with disk hernias, is described. Measures of the efficacy of mechanotherapy are presented − results were excellent in 68.3%, good in 21.4%, and satisfactory in 7.1%.

The Effectiveness of Additional Methods of Decompression in Patients with Supratentorial Dislocation of the Brain

The aim of the study is to evaluate the effectiveness of additional methods of external and internal decompression in patients with supratentorial dislocation in focal lesions of the cerebral hemispheres. Materials and methods: A retrospective analysis of 219 cases of supratentorial compression of the brain in patients hospitalized in the Clinic of Neurosurgery of the National Hospital of the Kyrgyz Republic was conducted. In the main group of 143 observations, the assessment of the severity of dislocation syndrome according to our 12-point scale was performed; according to the results of this assessment, after the eradication of the focal lesions, additional methods of external and/or internal decompression were used. The drainage of the lateral ventricles and the one-sided wide infratemporal decompressive craniotomy in severe cases supplemented by the microsurgical resection of the mediobasal parts of the temporal lobe were performed. Results: The analysis of the study showed an increase in unfavorable outcomes with the growth of the severity of DS. Thus, the gross residual effects found in stage I in 17.4% of the patients, in stage II were already found in 43.0%, and in stage IV - 69.4% of the observations. The group with fatal outcomes was even more demonstrative, which showed a clear increase in the number of deaths of patients as the severity of the dislocation progressed. Among patients with DS in stage I, 19.4% died, while in stage III - 32.1 %, and in stage V (the most severe) – 2 of 3 patients died, making up 66.7% of this group. The total number of deaths in both groups was 51 cases (23.2%); at that a significantly smaller percentage of failures of the treatment (p &lt;0.05) was found in patients of the main group making up 20.2%, compared to 29.0% of the control group. Conclusion: the findings of the clinical and instrumental examinations of patients in the postoperative period confirm the high effectiveness of methods of additional external and internal decompression, a high percentage of survival of patients in the main group and a decrease in the number of deaths in the treatment compared to the control group.