The internal contact nonlinear characteristics caused by the quasi-static properties of high-speed ball bearing is taken as a breakthrough point. Based on the L-P fatigue life theory, the bearing parameters and the preload load are used as the constraint variables to establish an overall bearing life extension model. Then, combined with the influence of geometric parameters on the osculation, the influence mechanism between spin-to-roll ratio and the life of the bearing are studied under the individual variation of the geometric parameters. Finally, the variation law of the bearing life, frictional heat generation and spin-to-roll ratio under the coupling changes of various parameters, and the priority of each parameter on the bearing life sensitivity, are investigated. The results show that the bearing life could be prolonged when the initial contact angle and the number of rolling elements increase but the inner and outer raceway curvature radius coefficients of the bearing and the preload force reduce. And the priority order of each parameter to bearing life sensitivity is as follows: the inner and outer raceway curvature radius coefficients shows the strongest influence on the bearing life, followed by the number of balls, and then the initial contact angle. This research provides a reliable theoretical basis for the design of high-speed ball bearings and life extension technology.