Intermediate-spin Iron Research Articles

Emission Mössbauer study of the stereochemical trigger that initiates cooperative interaction of hemoglobin subunits.

An important feature of Perutz's trigger mechanism for cooperativity in the reversible oxygenation of hemoglobin (Hb) is the tension along the histidine--metal linkage in deoxyHb and deoxycobaltohemoglobin (deoxy CoHb), supposedly due to the pull exerted by the globin on the metal atom. We have attempted to verify the existence of this pull by studying the emission Mössbauer spectra of deoxy 57CoHb and oxy 57 CoHb at different temperatures. The emission Mössbauer spectrum for none of the cobalt Hbs agrees with the absorption spectrum of the corresponding iron analog and, moreover, the spectrum of deoxy 57CoHb is characteristic of the intermediate-spin iron. These observations indicate that the daughter 57Fe atom is "frozen" almost in the same spatial situation as that of the parent 57Co. The protein is apparently holding the cobalt atom in position rather rigidly and, after the electron-capture decay of the 57Co atom, the protein does not permit the daughter 57Fe to move to a position characteristic of the iron atom.

Synthesis and low-temperature Moessbauer effect of several intermediate-spin iron(III) complexes

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis and low-temperature Moessbauer effect of several intermediate-spin iron(III) complexesH. Hollis Wickman and Anthony M. TrozzoloCite this: Inorg. Chem. 1968, 7, 1, 63–68Publication Date (Print):January 1, 1968Publication History Published online1 May 2002Published inissue 1 January 1968https://doi.org/10.1021/ic50059a013RIGHTS & PERMISSIONSArticle Views249Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (702 KB) Get e-Alerts Get e-Alerts