The multifaceted interrelationships of the various media are now considered to be a particular productive area of comparative strategy. The generalized typology among the types of intermedia at the present stage is considered to be the most fruitful and effective, in particular, ephrasis and intermedia – a particular manifestation of intermedia, the phenomenon of specific expressive mediation – mediation – of one media in the figurative field of another. Intermediate format, developed by the interaction of different sign systems and the content encoded by them, mainly – literature and other arts with emphasis on the sign and semantic correspondence of comparisons, has significant artistic effectiveness. At the same time, the preferred determinant of ephrasis as a description of a work of art in a literary text is suggested to be its relation to a specific work of authorship, although it also assumes the spread of the ephrasis to similar or non-existent but genre conventional art variants with a pre-eminent inheritance of the corresponding art. In determining the universal common principles of organizing such sovereignty of sign systems, positioned in the status of local variants of different discursive practices in the process of their syncretic interaction in the literary dimension, effective for illuminating the raised issue are primarily the tendencies of the extracurricular direction of literary criticism, initiated by the first concept. the imposition and intersection of semantic spaces capable of generating new meaning. The empiricism of intermedia and ephrasis is vividly and convincingly actualized in the novels of the prominent Serbian writer M. Pavic. Intermediate and extravagant improvisations are evident in the complex, multifaceted organization of the poetics of the novel form, emphasized in literary works, which brought this postulate to the level of traditional scientific views. Innovative creative experience of the artist, covered in the works of «Khazar Dictionary», «Inner Side of the Wind», «Last Love in Constantinople», «The Second Body», attests to the individual sophistication, content, precision of design and variety of potential, meaningfulness, significance poetics of syncretism of the arts to the organizational form-meaning components of the figurative structure of the novel as a whole.