In multiple-input multiple-output (MIMO) multiple automatic repeat request (ARQ) systems, multiple streams with independent hybrid ARQ (HARQ) processes can be simultaneously sent. Thus, the interference from other streams can affect future retransmissions of a packet as well as the current transmission, and proper management of interference at the receiver is required. Therefore, in this paper, a post-cancellation-based log-likelihood ratio (LLR) refining scheme is proposed for MIMO multiple ARQ (MMARQ) systems. In the proposed scheme, after the end of the entire conventional reception procedure for packet decoding, LLR refining is performed for the non-terminated packets that will be sent during the next transmission time interval. For LLR refining, the packet cancellation is performed to cancel only the successfully decoded packets. Thus, the LLRs of the non-terminated packets are refined without any error propagation, including the inter-transmission error propagation. Consequently, the proposed scheme can compensate for the interference problem in MMARQ systems and improve system performance. In order to utilize the error detection results of decoded codewords, the proposed scheme should be performed after the end of the entire reception procedure for packet decoding. Therefore, as the post-processing scheme, the proposed scheme can be employed to any existing LLR-level combining-based MMARQ receiver without changing the original procedure. Simulation results verify that the proposed scheme can significantly improve the error performance and throughput of MMARQ systems, especially for hard-decision interference cancellation-based receivers and high-order modulation. In addition, compared with the conventional reception procedure, the proposed scheme requires a smaller computational complexity in most of the simulated SNR region. Therefore, the proposed LLR refining scheme can be considered as an effective and practical post-processing scheme for an MMARQ receiver.