Interface Disorder Research Articles

Effect of residual stress and microstructure on mechanical properties of sputter-grown Cu/W nanomultilayers

The combination of the high wear resistance and mechanical strength of W with the high thermal conductivity of Cu makes the Cu/W system an attractive candidate material for heat sinks in plasma experiments and for radiation tolerance applications. However, the resulting mechanical properties of multilayers and coatings strongly depend on the microstructure of the layers. In this work, the mechanical properties of Cu/W nanomultilayers with different densities of internal interfaces are systematically investigated for two opposite in-plane stress states and critically discussed in comparison with the literature. Atomistic simulations with the state-of-the-art neural network potential are used to explain the experimental findings of Young’s modulus and hardness. The results suggest that the microstructure, specifically the excess free volume associated with porosity and interface disorder interconnected with the stress state, has a great impact on the mechanical properties, notably Young’s modulus of Cu/W nanomultilayers.

Evaluation of the effect of vitreomacular interface disorders on anti-VEGF treatment in patients with diabetic macular edema in real life: MARMASIA study group report No. 10.

The aim of this study is to investigate the effect of vitreomacular interface disorders (VMID) on treatment response in patients treated with anti-vascular endothelial growth factor (anti-VEGF) due to diabetic macular edema (DME). Three hundred seventy-seven eyes of 239 patients in the MARMASIA Study Group who received intravitreal anti-VEGF treatment (IVT) due to DME were included in the study. The group 1 consisted of 44 eyes of the patients who had not received any treatment before, were followed up regularly for 24months after at least a 3-month loading dose, and suffered from VMID such as epiretinal membrane, vitreomacular adhesion or traction, and lamellar hole. The group 2 consisted of 333 eyes of the patients without VMID. Best-corrected visual acuity (BCVA) and central macular thickness (CMT) of the patients at baseline, 3rd month, 6th month, 1st year and 2nd year follow-ups were measured. The mean age of the Groups 1 and 2 was 67.1 ± 11.3 and 61.9 ± 10.2 years, respectively. 61.3% of the group 1 and 58.8% of the group 2 were female (p > 0.05). The duration of diabetes was 19.2 ± 3.7 and 15.8 ± 3.2 years, respectively, and the number of follow-ups was 16.09 ± 4.68 and 12.06 ± 4.58, respectively in the groups (p < 0.001, 0.001, respectively). The number of IVT was 7.13 ± 2.71 and 7.20 ± 2.22, respectively in the groups 1 and 2 and no statistically significant difference was observed between them (p = 0.860). According to logMAR, BCVA values at baseline were 0.63 ± 0.24 and 0.59 ± 0.26 (p = 0.29), respectively, in the groups and the amount of change in BCVA at the end of the 2nd year was -0.02 ± 0.48 in the group 1 and -0.12 ± 0.48 in the group 2. It was observed as 0.48 (p = 0.13). Although the increase in BCVA was greater at all follow-ups in the group 2 compared to their initial examination, no significant difference was observed between the groups in terms of BCVA change. The CMT values of the groups at baseline were 442.5 ± 131.3µm and 590.9 ± 170.6µm, respectively (p = 0.03) The decrease in CMT after IVT was significantly greater in the group 2 at all follow-ups when compared to the first group (p < 0.05). While the presence of VMID in DME patients receiving IVT did not affect visual results, it negatively affected the anatomical response and macular edema morphology. The presence of VMID at baseline affected the success of IVT. It should be taken into consideration that VMID may resolve spontaneously or with IVT, and new cases of VMID may occur in patients during the treatment process.

Effects of SiO2 cap annealing on MOS interfaces formed on Mg-doped p-type GaN surface

In this paper, we report the effects of 800 °C SiO2 cap annealing on the Al2O3/p-type GaN (p-GaN):Mg and SiO2/p-GaN:Mg interfaces formed at relatively low temperatures, as determined by X-ray photoelectron spectroscopy (XPS) and sub-bandgap-light-assisted capacitance–voltage (C–V) measurement. For the sample with capless annealing at 800 °C and subsequent HF treatment before the Al2O3/p-GaN interface formation by atomic layer deposition at 300 °C, its C–V characteristics indicated the existence of high-density midgap states. By SiO2 cap annealing and subsequent HF treatment to remove the cap layer, we found that the Al2O3/p-GaN interface showed a reduction in midgap state density. The same effect was confirmed at the SiO2/p-GaN interface. Taking this finding and XPS results together, we consider the possibility that SiO2 cap annealing at 800 °C and the subsequent HF treatment prior to the formation of the Al2O3/p-GaN and SiO2/p-GaN interfaces led to the reduction of interface disorder.

Vitreoretinal Interface Abnormalities in Patients With Retinal Vein Occlusion in a Tertiary Referral Center.

The purpose of this study is to investigate the prevalence of vitreoretinal interface (VRI) disorders in patients with retinal vein occlusion (RVO) and to evaluate the impact of VRI abnormalities on the treatment outcomes of macular edema secondary to RVO using intravitreal aflibercept. Participants in this prospective study were consecutive patients with macular edema secondary to RVO, who received intravitreal aflibercept injections. At baseline, best-corrected visual acuity (BCVA) was assessed, and spectral domain-optical coherence tomography (SD-OCT) was performed to measure central subfield thickness (CST) and to evaluate the presence of VRI disorders, namely, vitreoretinal adhesion (VMA), vitreoretinal traction (VMT), epiretinal membrane (ERM), lamellar macular hole (LMH), and full-thickness macular hole (FTMH). The primary outcomes were the prevalence of various VRI disorders in patients with RVO and the impact of VRI disorders on BCVA and CST after aflibercept treatment in such patients. At baseline, 16.1% of patients had VMA, 3.2% VMT, 18.3% ERM, and 1.1% LMH. There were a statistically significant improvement in BCVA and a decrease in CST in RVO patients over time. There was no statistically significant difference regarding BCVA and CST at baseline and until month 24 after treatment between patients with VRI disorders and those without VRI disorders. However, the mean number of injections during the follow-up period was higher in the group with VRI disorders (9.4±2.1) compared to those without VRI disorders (8.1±0.7, p=0.0002). The prevalence of VRI disorders in patients with RVO was 16.1% for VMA, 3.2% for VMT, 18.3% for ERM, and 1.1% for LMH. VRI disorders were not found to affect the anatomical and visual outcomes after intravitreal aflibercept treatment in patients with RVO, although more intravitreal injections were needed in patients with VRI disorders.

Modified ILM flap techniques versus classical inverted ILM flap technique for large macular holes: a systematic review and meta-analysis of randomized controlled trials

BackgroundMacular holes (MHs) constitute a vitreoretinal interface disorder that occurs when structural abnormalities in the fovea lead to impaired central vision. The standard treatment for MHs is mainly surgical. Using an inverted internal limiting membrane (ILM) flap has enhanced the success rates of MH surgeries. This systematic review and meta-analysis aimed to compare the classical inverted ILM flap technique to modified ILM flap techniques for managing large MHs.MethodsWe searched Medline, Embase, and CENTRAL. We included randomized controlled trials (RCTs) that compared the classic inverted ILM flap technique to modified ILM flap techniques as initial surgical treatment of eyes with large MHs of more than 400 microns. We sought to evaluate the following outcomes: (1) MH closure. (2) Best-corrected visual acuity (BCVA). (3) Foveal closure type (4) Rate of ellipsoid zone (EZ) defects and external limiting membrane (ELM) defects. The standardized mean difference (SMD) was used to represent continuous outcomes, while the risk ratio (RR) was used to represent dichotomous outcomes.ResultsFour RCTs that enrolled 220 participants were deemed eligible. The analysis revealed no statistically significant differences in MH closure between both groups (95% CI: 0.20, 7.96; P = 0.81). No statistically significant differences in mean BCVA were found at 1 and 3 months between both groups (SMD: 0.04; 95% CI: −0.16, 0.23; P = 0.70 and SMD: −0.167; 95%CI: −1.240, 0.906; P = 0.760, respectively). In addition, there were no significant differences between the two groups in the pattern of foveal closure, namely U-shape, V-shape, and flap open at 3, 6, and 12 months (RR: 0.87; 95% CI: 0.67, 1.12; P = 0.28, RR: 0.96; 95% CI: 0.58, 1.61; P = 0.89, and RR: 1.95, 95% CI: 0.26, 14.50; P = 0.51, respectively). Finally, the analysis showed no statistically significant difference in both groups’ EZ and ELM defect rates at 3, 6, and 12 months (RR: 1; 95% CI: 0.85; 1.18: P = 1 and RR: 1.14; 95% CI: 0.90, 1.45; P = 0.27).ConclusionMacular holes (MHs) constitute a vitreoretinal interface disorder that occurs when structural abnormalities in the fovea lead to impaired central vision. The standard treatment for MHs is mainly surgical. Using an inverted internal limiting membrane (ILM) flap has enhanced the success rates of MH surgeries. This systematic review and meta-analysis aimed to compare the classical inverted ILM flap technique to modified ILM flap techniques for managing large MHs.

Nanoironing van der Waals Heterostructures toward Electrically Controlled Quantum Dots.

Assembling two-dimensional van der Waals (vdW)-layered materials into heterostructures is an exciting development that sparked the discovery of rich correlated electronic phenomena. vdW heterostructures also offer possibilities for designer device applications in areas such as optoelectronics, valley- and spintronics, and quantum technology. However, realizing the full potential of these heterostructures requires interfaces with exceptionally low disorder which is challenging to engineer. Here, we show that thermal scanning probes can be used to create pristine interfaces in vdW heterostructures. Our approach is compatible at both the material- and device levels, and monolayer WS2 transistors show up to an order of magnitude improvement in electrical performance from this technique. We also demonstrate vdW heterostructures with low interface disorder enabling the electrical formation and control of quantum dots that can be tuned from macroscopic current flow to the single-electron tunneling regime.

Assessment of Zonular Integrity in Phakic Eyes Following Pars Plana Vitrectomy Using Ultrasound Biomicroscopy: A Prospective Paired Eye Comparative Study

To assess zonular integrity in phakic patients post vitrectomy using ultrasound biomicroscopy (UBM). Prospective, comparative, nonrandomized, double-masked, paired eye study. We used ultrasound biomicroscopy (UBM) to evaluate phakic patients with a history of unilateral pars-plana vitrectomy. (1) phakic patients with history of pars plana vitrectomy in one eye as the only procedure; (2) normal unoperated fellow eye; and (3) complete gas or air resolution from the vitreous cavity at the time of UBM assessment. (1) monocular patients; (2) history of intraoperative lenticular trauma; (3) the use of silicone oil tamponade; (4) history of trauma or pseudoexfoliation in either eye; (5) history of other ocular conditions that can affect the integrity of zonules, such as uveitis or ectopia lentis; (6) eyes with extreme myopia or long axial length (> -8.00 D or >30.0 mm); (7) history of intravitreal injection in either eye; (8) age <18 years. A high-frequency (50 MHz) UBM device was used by a masked technician to obtain radial section images from zonular bundles at 8 different clock positions. Image quality was assessed in real time, captured, and saved. Two experienced masked observers (H.C. and C.B.) then assessed the quality of the images and graded the zonular findings. Only patients with adequate studies have been included. A unique grading system that was specifically devised for this study was used as the following: (0) clear, well-defined zonule(s); (1) uneven, disrupted zonules or stretched zonules; and (2) extensive loss of zonules. Each clock hour was graded according to this system and the total score was then calculated for each eye. In the primary outcome, 2 main groups were analyzed: vitrectomized eyes and healthy contralateral nonvitrectomized eyes. The mean total UBM score (TUS) from each group was compared and analyzed. Thirty-five patients were recruited into this study. Eleven patients were male and 24 were female. The mean age was 66.3 years. Thirty patients had vitrectomy for vitreomacular interface disorders (either macular hole or epiretinal membrane), 1 patient had vitreous hemorrhage and the remaining 4 patients had rhegmatogenous retinal detachments. With regard to tamponade agents, SF6 was used in 21 (60%) patients, air in 9 (26%) patients, and C3F8 in 5 (14%) patients. The mean TUS in the vitrectomized eyes was 2.28 (SD 1.83) vs 2.24 (SD 1.77) in the nonvitrectomized eyes (P = .9531). Overall, in the comparative analysis of mean scores based on 2 graders' assessments for each clock position in vitrectomized and nonvitrectomized eyes, there were no significant differences noted between the groups. This study found no evidence for a difference in the mean total UBM score in eyes following vitrectomy when compared to their contralateral healthy, nonvitrectomized eyes. This likely indicates that vitrectomy may not affect the integrity of zonules in phakic patients, at least for patients with vitreomacular interface disorders undergoing uncomplicated surgery.

Modeling Si/SiGe quantum dot variability induced by interface disorder reconstructed from multiperspective microscopy

SiGe heteroepitaxial growth yields pristine host material for quantum dot qubits, but residual interface disorder can lead to qubit-to-qubit variability that might pose an obstacle to reliable SiGe-based quantum computing. By convolving data from scanning tunneling microscopy and high-angle annular dark field scanning transmission electron microscopy, we reconstruct 3D interfacial atomic structure and employ an atomistic multi-valley effective mass theory to quantify qubit spectral variability. The results indicate (1) appreciable valley splitting (VS) variability of ~50% owing to alloy disorder and (2) roughness-induced double-dot detuning bias energy variability of order 1–10 meV depending on well thickness. For measured intermixing, atomic steps have negligible influence on VS, and uncorrelated roughness causes spatially fluctuating energy biases in double-dot detunings potentially incorrectly attributed to charge disorder. Our approach yields atomic structure spanning orders of magnitude larger areas than post-growth microscopy or tomography alone, enabling more holistic predictions of disorder-induced qubit variability.

Enhancement of Carrier Mobility in Multilayer InSe Transistors by van der Waals Integration.

Two-dimensional material indium selenide (InSe) holds great promise for applications in electronics and optoelectronics by virtue of its fascinating properties. However, most multilayer InSe-based transistors suffer from extrinsic scattering effects from interface disorders and the environment, which cause carrier mobility and density fluctuations and hinder their practical application. In this work, we employ the non-destructive method of van der Waals (vdW) integration to improve the electron mobility of back-gated multilayer InSe FETs. After introducing the hexagonal boron nitride (h-BN) as both an encapsulation layer and back-gate dielectric with the vdW interface, as well as graphene serving as a buffer contact layer, the electron mobilities of InSe FETs are substantially enhanced. The vdW-integrated devices exhibit a high electron mobility exceeding 103 cm2 V-1 s-1 and current on/off ratios of ~108 at room temperature. Meanwhile, the electron densities are found to exceed 1012 cm-2. In addition, the fabricated devices show an excellent stability with a negligible electrical degradation after storage in ambient conditions for one month. Electrical transport measurements on InSe FETs in different configurations suggest that a performance enhancement with vdW integration should arise from a sufficient screening effect on the interface impurities and an effective passivation of the air-sensitive surface.

TWO YEARS DESCRIPTIVE STUDY OF MACULAR HOLE PATIENTS OPERATED IN DR. KARIADI GENERAL HOSPITAL, SEMARANG

Introduction &amp; ObjectivesMacular hole (MH) is a vitreomacular interface disorder that could cause visual impairment. Clinicalcharacteristics of MH are important for predicting MH treatment outcomes. This study purpose wasto describe MH patients’ characteristics and postoperative outcomes in Dr. Kariadi Hospital.&#x0D; MethodsA retrospective study held on January 2021–December 2022 utilizing patients’ medical records.Preoperative data: sex, age, symptoms, duration of symptoms, origin, preoperative visual acuity(VA), modified Gass classification stage, macular hole index (MHI), and hole forming factor (HFF)were obtained. Postoperative outcomes data: postoperative VA and anatomical closure were alsocollected.&#x0D; Results20(20 eyes) patients were obtained, with 14(70%) female, 12(60%) aged &gt;60 years old, 13(65%)metamorphopsia, 12(60%) central visual loss, 10(50%) preoperative VA 6/24-6/60, 10(50%) durationof symptoms &lt;3 months, and 16(80%) idiopathic origin. OCT (Ocular Coherence Tomography)findings revealed base diameter mean was 780,7 um(+ SD 312). 13 patients (65%) stage 3 of MH,12(60%) MHI &lt;0,5, 12(60%) HFF &gt; 0,9. All patients underwent MH surgery procedures.Postoperative examination showed 10 patients(50%) with VA 6/6-6/20. 11(100%) with preoperativeVA&gt;6/60, 10(100%) with duration of symptoms &lt;3 months, 8(100%) with MHI &gt; 0,5, and 11(100%)with HFF &gt; 0,9 had improved visual acuity and anatomical closure. It also revealed 17(85%) hadanatomical closure.&#x0D; ConclusionThe most common characteristics found in MH patients were female sex, age &gt;60 years old, anddisorder of idiopathic origin. Preoperative VA, duration of symptoms &lt;3 months before surgery, MHI&gt; 0,5, and HFF &gt; 0,9 were positive prognostic factors for better postoperative functional andanatomical outcomes.

TWO YEARS DESCRIPTIVE STUDY OF MACULAR HOLE PATIENTS OPERATED IN DR. KARIADI GENERAL HOSPITAL, SEMARANG

Introduction and Objective: Macular hole (MH) is vitreomacular interface disorder that could cause visual impairment. Clinical characteristics of MH are important for predicting MH treatment outcomes. This study purpose was to describe MH patients’ characteristics and postoperative outcomes in Dr. Kariadi Hospital. Method: A retrospective study held on January 2021–December 2022 utilizing patients’ medical records. Preoperative data: sex, age, symptoms, duration of symptoms, origin, preoperative visual acuity (VA), modified Gass classification stage, macular hole index (MHI), and hole forming factor (HFF) were obtained. Postoperative outcomes data: postoperative VA and anatomical closure were also collected. Result: 20(20 eyes) patients were obtained, with 14(70%) female, 12(60%) aged &gt;60 years old, 13(65%) metamorphopsia, 12(60%) central visual loss, 10(50%) preoperative VA 6/24-6/60, 10(50%) duration of symptoms &lt;3 months, and 16(80%) idiopathic origin. OCT (Optical Coherence Tomography) findings revealed base diameter mean was 780,7 um(+ SD 312). 13 patients (65%) stage 3 of MH, 12(60%) MHI &lt;0,5, 12(60%) HFF &gt; 0,9. All patients underwent MH surgery procedures. Postoperative examination showed 10 patients(50%) with VA 6/6-6/20. 11(100%;p&lt;0,001) with preoperative VA&gt;6/60, 10(100%;p&lt;0,001) with duration of symptoms &lt;3 months, 8(100%;p=0,012) with MHI &gt; 0,5, and 11(100%;p&lt;0,001) with HFF &gt; 0,9 (p&lt;0,001) had improved visual acuity and anatomical closure. It also revealed 17(85%) had anatomical closure. Conclusion: The most common characteristics found in MH patients were female sex, age &gt;60 years old, and disorder of idiopathic origin. Preoperative VA, duration of symptoms &lt;3 months before surgery, MHI &gt; 0,5, and HFF &gt; 0,9 were positive prognostic factors for better postoperative functional and anatomical outcomes.

Selective multi–view time–frequency decomposed spatial feature matrix for motor imagery EEG classification

Decoding brain activity from non-invasive motor imagery electroencephalograph (MI-EEG) has garnered significant attentions for brain-computer interface (BCI) and brain disorders. Notably, owing to the remarkable advances in feature representation, extracting and selecting discriminative features in EEG decoding has gained widespread popularity in recent years. However, many EEG studies suffer from limited sample sizes with low signal-to-noise ratio, making it difficult to effectively represent complementary features in a single view. To address this fundamental limitation, this paper proposes a novel method to Selective extract the Multi-View Time-Frequency decomposed Spatial (S-MVTFS) feature matrix, which employs spatial features from Euclidean and Riemannian spaces based on time–frequency decompositions. It selectively extracts discriminative features on manifold embedded space and classifies feature matrix through sparse support matrix machine. The proposed method has been systematically benchmarked on three BCI competition MI-EEG datasets, and its classification performance surpasses several state-of-the-art methods. Notably, the S-MVTFS method achieved average classification improvements of 0.45%, 2.28%, and 2.04% on BCI-III dataset 4a, BCI-IV dataset 1, and BCI-IV dataset 2a, respectively. Moreover, it effectively captures meaningful temporal varying and spatially coupled features with parameter insensitivity. Our method therefore provides a novel MI-EEG tailored feature representation for decoding brain activity.

Tunable electronic properties and Schottky barrier in Janus Ti3C2FO and TMD heterostructures by interface atomic species and disorder

In two-dimensional (2D) Janus MXenes materials, asymmetric disordered surface termination can greatly enhance material functionality. In this work, considering surface termination composition and disorder in 2D Janus MXenes, we designed five models of Janus Ti3C2FO, and then systematically investigated the electronic and contact properties of the corresponding Janus Ti3C2FO and TMD (TMD=WS2, MoS2 and WSe2) heterostructures using the density functional theory method. When the top and bottom surfaces of Janus Ti3C2FO are purely occupied by F and O atoms, respectively, Janus Ti3C2FO shows a pseudogap, which disappears in the presence of the mixed F and O atoms. It was found that the surface termination atomic species and disorder of Janus Ti3C2FO can effectively control the contact nature and Schottky barrier height (SBH) of these Ti3C2FO/TMD heterostructures and lead to a different response of their contact properties to the interlayer distance and external electric field. The presence of pure F atoms at the interface induces in the SBHs a strong dependence on the decrease in interlayer distance, while the pure O atoms causes both ΦB,n and ΦB,p to be almost pinned. Our study provides important new insight into the tuning of contact properties of MXenes/TMD heterostructures.

Creating a "Brain-Mind-Body Interface Disorders" Diagnostic Category Across Specialties.

Creating a "Brain-Mind-Body Interface Disorders" Diagnostic Category Across Specialties.

Interface disorder as the cause for the kinetic Rashba-Edelstein effect and interface spin-Hall effect at a metal-insulator boundary

Interface disorder as the cause for the kinetic Rashba-Edelstein effect and interface spin-Hall effect at a metal-insulator boundary

Choroidal vascularity index changes in different treatments for vitreomacular traction

IntroductionThe aim of this study was to examine if choroidal vascularity index (CVI) is different in eyes with unilateral vitreomacular traction (VMT) from their healthy fellow eyes; and whether different treatments affect the CVI. MethodsThe baseline and 8-week post treatment CVIs of 56 unilateral VMT patients that underwent spontaneous resolution (n = 30), vitreoretinal surgery (n = 16) or pneumatic vitreolysis (n = 10) were compared with fellow eyes using paired samples t-test. Partial correlation analyses correcting age and gender was used for calculations between treatment groups. P values < 0.05 were considered statistically significant. ResultsThe mean baseline CVI for VMT and control eyes had no statistically significant difference (p = 0.81, r= -0.38). The post traction release follow-up CVI of VMT eyes and contralateral eyes had no significant difference (p = 0.12, r = 0.49). In spontaneous resolution group, vitreoretinal surgery group and pneumatic vitreolysis group the baseline and follow up CVIs of VMT eyes were statistically similar (p = 0.72, p = 0.32 and p = 0.79 respectively).Spontaneous detachment patients’ CVIs showed a 0.57±5.81% increase, vitreoretinal surgery group had a reduction of 1.098±4.76%, and the pneumatic vitreolysis patients showed a CVI reduction of 0.307±4.24%. However, none of these changes was found to be statistically significant when compared between the groups (p = 0.21, r = 0.02). DiscussionPrevious studies have argued that vitreomacular traction might have a role on the choroidal changes seen in the vitreoretinal interface disorders. This study has shown that VMT alone does not cause any significant changes in choroidal vascular index pre or post traction release.

A Prospective Randomized Study Comparing 27-Gauge Vitrectomy to 23-Gauge Vitrectomy for Epiretinal Membranes and Full-Thickness Macular Holes.

To compare the surgical and clinical outcomes of 27-gauge vitrectomy and 23-gauge vitrectomy. We conducted a single-center, prospective, randomized study. Fifty-three patients affected by vitreoretinal interface disorders (epiretinal membranes and macular holes) were randomly scheduled to undergo 27-gauge (28 patients) or 23-gauge (25 patients) pars plana vitrectomy. The presence of any potential factor of increased baseline inflammation or eye anatomy influencing the surgery was criteria for exclusion. The time of surgery, postoperative intraocular pressure (IOP), state of sclerotomy wounds, rate of complications, postoperative pain, and indicators of inflammation were studied. We also introduced a new parameter to compare intraocular inflammation after surgery, given by the change in the number of intraretinal hyperreflective foci (HRF). The 27-gauge vitrectomy was 1.28 min longer than 23-gauge vitrectomy (P < 0.05). The day after surgery, the mean IOP value was significantly higher in the 27-gauge group (16.12 mmHg versus 13.04 mmHg in the 23-gauge group,P < 0.05), but this difference disappeared in successive follow-ups and the sclerotomy wounds closed after 2 weeks in the both groups. The rate of postoperative hypotony did not significantly differ in the two groups (10.71% in the 27-gauge group and 8% in the 23-gauge group the day after the surgery,P = 0.94). Less postoperative eye redness was seen in 27-gauge eyes (value 1 on the scale) compared to 23-gauge (value 2 on the scale) (P < 0.05), but there was no significant difference in intraocular inflammation (cells, Tyndall, and number of HRF,P > 0.05 for all). The 27-gauge vitrectomy may have better outcomes in terms of IOP maintenance and cause less redness after the surgery but with a slightly prolonged surgery time and no other differences under other parameters (inflammation, rate of complications, postoperative pain, visual gain, and closure of the sclerotomy wounds).

COMPARATIVE ANALYSIS OF THE ACCURACY OF INTRAOCULAR LENS POWER CALCULATION FORMULAS IN COMBINED PHACOVITRECTOMY

The retrospective study was conducted in Bakhtawar Amin &amp; Nishtar Medical Hospital from January 2022 to January 2023 to evaluate the accuracy of three new-generation formulas, using measurements from IOL-Master 700, in patients with vitreomacular interface disorders undergoing combined phacovitrectomy. A total of 110 patients (110 eyes) were included; Group I had 110 eyes, and Group II had 100 eyes. Group I had patients with normal phacoemulsification, and Group II had normally combined phacovitrectomy. For both groups, predictions from 8 IOL power calculation formulas were recorded. Results showed insignificant differences between Group I (P=.934) and Group II (P=.971).&#x0D; Regarding the mean prediction error of formulas In Group I, the Kane formula had the best outcome.in Group II, the Kane formula has the lowest MAE. The Kane formula had the lowest MAE in Group III, though the difference was not statistically significant. It is concluded that the Kane formula consistently had the best rank, independent of the Group.

Dry eye parameters measured with an ocular surface analyzer in eyes after vitrectomy for vitreomacular interface disorders.

Dry eye disease (DED) might be caused by multiple ocular surgical interventions. The aim of the study was to estimate the extent of DED in patients undergoing core vitrectomy for vitreoretinal interface disorders. In this prospective observational study, we included patients with 12 months of follow-up after vitrectomy. The following data were collected as controls: age, sex, best-corrected visual acuity before and after surgery, and phakic status. In OSA (ocular surface analysis), the following parameters were evaluated: NIBUT (non-invasive tear break-up time), sltDear (thickness of the lipid layer), Meibomian gland (MGD) loss, and the height of tear meniscus. Shapiro-Wilk test, Wilcoxon rank-sum test, and Mann-Whitney U tests were used for statistical analysis. We evaluated 48 eyes of 24 patients (10 men, 14 women; 64.63 ± 14.10 years) 1 year after vitrectomy. From the analyzed ocular surface parameters, NIBUT was significantly lower in operated versus non-operated eyes (P = 0.048). The higher the level of difference in MGD loss between both eyes, the higher the level of difference in NIBUT between both eyes (rs = 0.47, P = 0.032). NIBUT levels were still decreased 12 months after vitrectomy. Patients with more pronounced MGD loss or decreased NIBUT levels in the fellow eye were more likely to experience such disorders. The tear meniscus height was lower in patients undergoing surgery for retinal detachment than in those with vitreoretinal disorders. This might allow the suggestion to include artificial tears in pre- and post-operative care in vitrectomized eyes.

Proximity induced moment at Pt/Co interfaces and isolated skyrmion bubble stabilization at zero magnetic field

Magnetic multilayers with heavy metal/ferromagnetic interfaces play an important role in data storage and spintronics due to magnetic phenomena such as perpendicular magnetic anisotropy (PMA) and magnetic skyrmion stabilization. Properties such as saturation magnetization (Ms), PMA, and interfacial Dzyaloshinskii–Moriya interaction (iDMI) can be tuned by stacking engineering to tailor the multilayer magnetic ground state. Here, it is demonstrated that isolated skyrmion bubbles can be stabilized at zero magnetic field in nominally symmetric Pt/Co/Pt multilayers grown by magnetron sputtering. Interface disorder and asymmetry are strongly enhanced as the Co layer is thinned, leading to nonzero iDMI and Pt proximity induced moment (PIM) that affects both the multilayer Ms and PMA. The interplay between PIM and the iDMI is behind the nucleation of skyrmion bubbles, highlighting the importance of controlling the interface phenomena to develop devices for future applications. These results also manifest the importance of considering the PIM to determine the correct magnetic parameters of ultrathin films on the zero-field spin textures stability.