ADVERTISEMENT RETURN TO ISSUEHighlights from the ...Highlights from the LiteratureNEXTSome Items of Interest to Process R&D Chemists and EngineersAlan StevenAlan StevenCatSci Ltd, CBTC2, Capital Business Park, Wentloog, CardiffCF3 2PX, U.K.More by Alan Stevenhttps://orcid.org/0000-0002-0134-0918, Robert B. KargboRobert B. KargboUsona Institute, 277 Granada Drive, San Luis Obispo, California93401, United StatesMore by Robert B. Kargbohttps://orcid.org/0000-0002-5539-6343, Carlos MateosCarlos MateosDiscovery Chemistry Research and Technologies, Eli Lilly and Co., Avenida de la Industria 30, 28108Alcobendas, SpainMore by Carlos Mateoshttps://orcid.org/0000-0002-0189-4136, Andrei A. ZlotaAndrei A. ZlotaThe Zlota Company, LLC, 97 Brooksmont Drive, Holliston, Massachusetts01746-1770, United StatesMore by Andrei A. Zlotahttps://orcid.org/0000-0002-2048-9187, Christopher C. NawratChristopher C. NawratMerck & Co. Inc., Rahway, New Jersey07065, United StatesMore by Christopher C. Nawrathttps://orcid.org/0000-0003-4550-9954, James P. PhelanJames P. PhelanMedicinal Chemistry, GlaxoSmithKline, 1250 South Collegeville Road, Collegeville, Pennsylvania19426, United StatesMore by James P. Phelanhttps://orcid.org/0000-0002-0058-0653, Alexandre BarthelmeAlexandre BarthelmeCenter of Expertise Drug Substance, UCB Pharma, Chemin Du Foriest 1, 1420Braine-l’Alleud, BelgiumMore by Alexandre Barthelme, Sylvain GuizzettiSylvain GuizzettiNovAlix, Building A: Chemistry, Bioparc, Bld. Sébastien Brant, BP 30170, F-67405Illkirch Cedex, FranceMore by Sylvain Guizzettihttps://orcid.org/0000-0003-4656-2431, and John Knight*John KnightJKonsult Ltd, Meadow View, Cross Keys, HerefordHR1 3NT, U.K.*Email: [email protected]More by John KnightCite this: Org. Process Res. Dev. 2023, 27, 1, 1–9Publication Date (Web):January 9, 2023Publication History Received21 December 2022Published online9 January 2023Published inissue 20 January 2023https://doi.org/10.1021/acs.oprd.2c00393Copyright © Published 2023 by American Chemical SocietyRIGHTS & PERMISSIONSArticle Views4434Altmetric-Citations-LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (3 MB) Get e-AlertsSUBJECTS:Aldehydes,Chemical reactions,Crystallization,Optimization,Organic compounds Get e-Alerts