Sn Interactions Research Articles

Organotin(IV) complexes of NSAID, ibuprofen, X‐ray structure of Ph3Sn(IBF), binding and cleavage interaction with DNA and in vitro cytotoxic studies of several organotin complexes of drugs

This study encompasses the synthesis and characterization of organotin(IV) derivatives of non‐steroidal anti‐inflammatory drug ibuprofen (IBF), viz. [(Me3Sn)(IBF)] (1), [(Bu3Sn)(IBF)] (2), [Ph3Sn(IBF)] (3), {[Me2Sn(IBF)]2O}2 (4) and [Bu2Sn(IBF)2] (5). The crystal structure of complex 3, [Ph3Sn(IBF)], indicates a highly distorted tetrahedral (td) geometry with anisobidentate mode of coordination of the carboxylate group with tin atom, and a similar structure has been proposed for other two triorganotin(IV) derivatives. Moreover, the DFT (density functional theory) calculation and other studies have verified a dimer distannoxane type of structure for complex 4, {[Me2Sn(IBF)]2O}2. Complex 5 has been found to exhibit a highly distorted octahedral geometry around the tin atom. To investigate the DNA binding profile of the synthesized complexes, viscosity measurement, UV–vis and fluorescence titrations were performed, which revealed an intercalative type of binding with DNA for IBF and complex 5 and external binding in case of the complexes 1 and 2; complexes 3 and 4 could not be studied owing to their insufficient solubility in tris buffer. Plasmid DNA fragmentation studies of IBF and complexes 1, 2 and 5 indicate that they cleaved the pBR322 plasmid potentially. Further, the drugs IBF {2‐[4‐(2‐methylpropyl)phenyl]propanoic acid}, MESNA (sodium 2‐mercaptoethane‐sulfonate), warfarin [2H‐1‐benzopyran‐2‐one,4‐hydroxy‐3‐(3‐oxo‐1‐phenylbutyl)], sulindac (2‐{5‐fluoro‐1‐[(4‐methanesulfinylphenyl) methylidene]‐2‐methyl‐1H‐inden‐3‐yl}acetic acid) and their corresponding organotin(IV) complexes 1–19 (complexes 6–19 were synthesized/reported previously) were screened in vitro for cytotoxicity against human cancer cell lines viz. DU145 (prostate cancer), HCT‐15 (colon adenocarcinoma), Caco‐2 (colorectal adenocarcinoma), MCF‐7 (mammary cancer), LNCaP (androgen‐sensitive prostate adenocarcinoma) and HeLa (cervical cancer), through MTT reduction assay and the cause of cell death was investigated through acridine orange/ethidium bromide staining of cells and DNA fragmentation assay. The probable structure–cytotoxicity relationship is also discussed. The major role of apoptosis along with small necrosis was also validated by flow cytometry assay using annexin V–fluorescein isothiocyanate and propidium iodide analysis.

Hydridoorganostannylene Coordination: Group 4 Metallocene Dichloride Reduction in Reaction with Organodihydridostannate Anions.

Organodihydridoelement anions of germanium and tin were reacted with metallocene dichlorides of Group 4 metals Ti, Zr and Hf. The germate anion [Ar*GeH2]− reacts with hafnocene dichloride under formation of the substitution product [Cp2Hf(GeH2Ar*)2]. Reaction of the organodihydridostannate with metallocene dichlorides affords the reduction products [Cp2M(SnHAr*)2] (M=Ti, Zr, Hf). ion of a hydride substituent from the titanium bis(hydridoorganostannylene) complex results in formation of cation [Cp2M(SnAr*)(SnHAr*)]+ exhibiting a short Ti–Sn interaction. (Ar*=2,6‐Trip2C6H3, Trip=2,4,6‐triisopropylphenyl).

Sulfated Tin Oxide as Highly Selective Catalyst for the Chlorination of Methane to Methyl Chloride

The chlorination of methane (CH4) is an attractive route to convert CH4 into more valuable chemicals. The selective formation of methyl chloride (CH3Cl) is a key process, but it is rather difficult to achieve with high selectivity due to a radical reaction. Catalytic ionic processes can be a solution. Herein, sulfated tin oxide (STO) was employed in the gas-phase catalytic chlorination of CH4. The STO catalyst exhibited high selectivity to CH3Cl (>96%) even at high CH4 conversion. By applying a suite of physicochemical characterizations, it is shown that the strong Lewis acid sites on STO generated by the interaction of Sn and surface sulfate groups are mainly responsible for the highly selective CH4 conversion. DFT calculations further revealed that STO surface can activate more Cl2 molecules in a heterolytic manner, leading to better catalytic performances as compared to SnO2 and sulfated zirconia catalysts.

Tin(II) Complexes Based on N-Alkyl-Substituted o-Amidophenolate Ligands: Acid–Base and Redox Transformations

New stannylene AdAPSn (I) based on 4,6-di-tert-butyl-N-adamantyl-o-aminophenol is synthesized and structurally characterized. Stannylene I in the crystalline state forms infinite chains due to intermolecular donor–acceptor Sn–N and metallophilic Sn···Sn interactions. The reactivities of compound I and earlier synthesized t-BuAPSn (II) are studied using their redox and acid–base reactions. Stannylenes I and II are inserted at the S–S bond of tetramethylthiuram disulfide to form the corresponding tin(IV) dithiocarbamate complexes. The reactions with soft one-electron oxidants involve the redox-active o-amidophenolate ligand and generate labile paramagnetic stannylenes studied by EPR spectroscopy. The presence of a lone electron pair at the low-valence tin atom is a reason for its basic properties, which is demonstrated for the reaction of compound I with nanocarbonyl iron. The structures of selected synthesized compounds are determined by X-ray diffraction analysis (СIF files CCDC nos. 1905419–1905421).

Molecular aggregations of bicyclodioxazastannone produced from multicomponent reactions involving functionalized 2-hydroxybenzaldehydes, α- or β-amino acids and a dimethyltin precursor

A series of novel bicyclodioxazastannone derived from ONO Schiff base ligands prepared from diazenylaryl functionalized 2-hydroxybenzaldehydes and α or β-amino acetates, viz., [Me2Sn(L1)]2 (1), [Me2Sn(L2)]2 (2), [Me2Sn(L3)(MeOH)]2 (3), [Me2Sn(L4)]n (4), [Me2Sn(L5)]n⋅nH2O (5), [Me2SnL6)]2 (6), [Me2Sn(L7)] (7A), [Me2Sn(L7)]2⋅C8H10 (7B) and [Me2Sn(L8)]n (8), with variously substituted Schiff bases L1-L8 generated in situ, were synthesized and structurally characterized. The crystal structures of compounds 1–8 revealed different structure types with five-, six- or seven-fold coordination of the metal center. Except for 7A, which crystallized in the form of a discrete mononuclear tin complex, intermolecular association through O→Sn interactions was observed. The resulting aggregates were molecular dimers with a central four-membered Sn2O2 ring (1, 2, 6 and 7A), 1D coordination polymers (4, 5 and 8) and a solvent adduct linked through both O–H⋅⋅⋅O hydrogen bonds and O⋅⋅⋅Sn contacts (3). In the presence of hydrogen bond donors such as O–H and N–H groups in the ligands, the molecular structures are further interconnected through O/N–H⋅⋅⋅O hydrogen bonds, giving in combination with the O⋅⋅⋅Sn contacts overall 2D layer-type assemblies. In solution, contrary to the β-alanine derivative 1, the 1H and 13C NMR spectra of compounds 2–8 displayed signals for the Me2Sn moieties because of diastereotopic environments according to the asymmetric nature of the ligand. The 119Sn NMR data of most of the compounds were acquired in DMSO‑d6 with the chemical shift displacements indicating six-coordinate tin atoms, which is in good agreement with the O→Sn adduct formation in the solid-state structures. The 119Sn NMR spectrum of compound 2 measured in CDCl3 indicates the presence of a mononuclear tin complex, as expected for a non-coordinating solvent.

Modification of Acidic Properties of the Support for Pt–Sn/BEA Propane Dehydrogenation Catalysts

Platinum–tin catalysts for propane dehydrogenation supported on a zeolite of the BEA framework type are studied. The presence of acid sites on the support leads to the occurrence of side reactions, which inhibit the achievement of a high propylene selectivity. To decrease the acidity of the support, the zeolite is subjected to dealumination with the preservation of the crystalline structure. The deposition of tin on this support leads to the incorporation of tin atoms into the zeolite framework, as confirmed by IR spectroscopy of adsorbed deuterated acetonitrile. The subsequent deposition of platinum leads to the occurrence of the Pt–Sn interaction, which provides a high selectivity for the target product and an increase in the agglomeration resistance of the active phase. In the presence of samples containing 0.5% of platinum and 0.5–1.0% of tin, at a reaction temperature of 550°C, a propane conversion of 26–28% at a propylene selectivity of up to 98.8% is achieved.

Photoswitching and photocatalytic functions of SnxCu1−xS nanostructures

Ultra-thin semiconducting nanostructures are garnering strategic importance in energy and environment remediation applications. In this regard, SnxCu1−xS nanostructures were processed through an eco-friendly chemical route and investigated in detail for photoswitching and photocatalytic functions. X-ray diffraction, FT-IR, Raman, UV–vis absorbance and high-resolution microscopic tools were initially used to examine the physico-chemical traits of SnxCu1−xS nanostructures. Ambiguous evidence for the substitution of Sn ions in place of Cu ions was attained through X-ray photoelectron spectroscopy. The photocatalytic performance of SnxCu1−xS systems was investigated through effective remediation of organic dye molecules under visible light. Scavenger based photocatalytic experiments were additionally carried out to infer the degradation mechanism. Type II p-n SnxCu1−xS/In2S3 heterojunction diodes were also demonstrated for the first time with improved electrical conductivity and photoelectrical performances. The rectification ratio, forward current values and photo switching capabilities of these diodes were noted to improve in the Current vs. Voltage (I-V) and Current vs. Time (I-T) curves as a function of Sn composition and applied bias potential. The excellent photo switching stability augments the photo generated carriers to be effectively separated along the p-n junctions. The enhanced photoelectronic and photocatalytic functionalities in SnxCu1−xS has finally been reasoned to the improved charge transfer kinetics in the respective architectures, resulting from the effective Sn interaction in hexagonal host lattice.

Theoretical study on Sn–Sb-based lead-free solder by ab initio molecular dynamics simulation

Abstract

Studies on the Interaction of [SnMe2Cl2(bu2bpy)] Complex with ct-DNA Using Multispectroscopic, Atomic Force Microscopy (AFM) and Molecular Docking

The interaction of SnMe2Cl2(bu2bpy)complex with calf thymus DNA (ct-DNA) has been explored following, using spectroscopic methods, viscosity measurements, Atomic force microscopy, Thermal denaturation and Molecular docking. It was found that Sn(IV) complex could bind with DNA via intercalation mode as evidenced by hyperchromism and bathochromic in UV–Vis spectrum; these spectral characteristics suggest that the Sn(IV) complex interacts with DNA most likely through a mode that involves a stacking interaction between the aromatic chromophore and the base pairs of DNA. In addition, the fluorescence emission spectra of intercalated methylene blue (MB) with increasing concentrations of SnMe2Cl2(bu2bpy) represented a significant increase of MB intensity as to release MB from MB-DNA system. Positive values of ΔH and ΔS imply that the complex is bound to ct-DNA mainly via the hydrophobic attraction. Large complexes contain the DNA chains with an average size of 859 nm were observed by using AFM for Sn(IV) Complex–DNA. The Fourier transform infrared study showed a major interaction of Sn(IV) complex with G-C and A-T base pairs and a minor perturbation of the backbone PO2 group. Addition of the Sn(IV)complex results in a noticeable rise in the Tm of DNA. In addition, the results of viscosity measurements suggest that SnMe2Cl2(bu2bpy) complex may bind with the classical intercalative mode. From spectroscopic and hydrodynamic studies, it has been found that Sn(IV)complex interacts with DNA by intercalation mode. Optimized docked model of DNA–complex mixture confirmed the experimental results.

Oxytocin Modulates the Intrinsic Dynamics Between Attention-Related Large-Scale Networks.

Attention and salience processing have been linked to the intrinsic between- and within-network dynamics of large-scale networks engaged in internal (default network [DN]) and external attention allocation (dorsal attention network [DAN] and salience network [SN]). The central oxytocin (OXT) system appears ideally organized to modulate widely distributed neural systems and to regulate the switch between internal attention and salient stimuli in the environment. The current randomized placebo (PLC)-controlled between-subject pharmacological resting-state fMRI study in N = 187 (OXT, n = 94; PLC, n = 93; single-dose intranasal administration) healthy male and female participants employed an independent component analysis approach to determine the modulatory effects of OXT on the within- and between-network dynamics of the DAN-SN-DN triple network system. OXT increased the functional integration between subsystems within SN and DN and increased functional segregation of the DN with both attentional control networks (SN and DAN). Whereas no sex differences were observed, OXT effects on the DN-SN interaction were modulated by autistic traits. Together, the findings suggest that OXT may facilitate efficient attention allocation by modulating the intrinsic functional dynamics between DN components and large-scale networks involved in external attentional demands (SN and DAN).

Ru‐Sn‐B/TiO2 catalysts for methyl oleate selective hydrogenation. Influence of the preparation method and the chlorine content

AbstractBACKGROUNDFatty alcohols are produced commercially by selective hydrogenation of fatty acid esters using copper‐chromium catalysts. To reduce drastic reaction conditions, ruthenium‐tin (Ru‐Sn) catalysts reduced with sodium borohydride (NaBH4) have been proposed. Chlorine (Cl) negatively affects the selectivity and activity of this catalytic system. To get further information on why Cl influences the selectivity negatively, this study investigated the influence of the preparation method on titania (TiO2)‐supported catalysts, which leads to catalysts with different Cl contents.RESULTSThe activity and selectivity were greatly affected by the Cl content, which depends on the metal impregnation method (co‐impregnation in excess of solution or co‐impregnation by incipient wetness) and the support pre‐calcination. Chlorine affects the Ru–Sn metal interaction, modifying the activity and selectivity. Catalysts with high Ru–Sn interaction are more selective to oleyl alcohol. Catalysts prepared by the co‐impregnation method exhibit bigger particles than catalysts prepared by the incipient wetness method, with agglomerated Ru3Sn7 cubic phase of 50 nm surrounded by amorphous Ru‐Sn.CONCLUSIONHigh interaction between Ru and Sn is preferred because segregated Ru species are not selective for the formation of oleyl alcohol. The electronic state of Ru0 is very important because small variations in the electron density lead to a decrease in the adsorption of hydrogen, or because Ru0‐H species do not have the adequate binding energy to produce the necessary ‘hydride form’. The Ru electronic state is modified by the Cl that surrounds it, decreasing its ability to adsorb hydrogen. © 2018 Society of Chemical Industry

New hypercoordinated diorganotin(IV) compounds with dithiocarbamato ligands. Synthesis and structural characterization

Several homo- and heteroleptic diorganotin(IV) dithiocarbamato halides of type RR'Sn(S2CNR″2)Cl [R = R' = Me, R'' = Me (1), Et (2); R = R' = nBu, R'' = Me (3), Et (4); R = 2-(Me2NCH2)C6H4, R' = Me, R'' = Me (5), Et (6)] and pseudo-halides of type RR'Sn(S2CNR″2)(NCS) [R = R' = Me, R'' = Me (7), Et (8); R = R' = nBu, R'' = Me (9), Et (10); R = 2-(Me2NCH2)C6H4, R' = Me, R'' = Me (11), Et (12); R' = nBu, R'' = Et (13), R' = 2-(Me2NCH2)C6H4, R'' = Me (14), Et (15)] were prepared by salt metathesis reactions, starting from either RR'SnCl2 or RR'Sn(NCS)2. In all compounds the dithiocarbamato ligand acts as a bidentate moiety. For the compounds 11–15, as well as for the species 5 and 6, of type RR'Sn(S2CNR″2)Cl, bearing aromatic groups with pendant arms attached to tin, the NMR spectra gave no clear evidence for a N→Sn coordination in solution at room temperature. The molecular structures determined by single-crystal X-ray diffraction for compounds 12 and 14, with one or two 2-(Me2NCH2)C6H4 groups, respectively, revealed the existence of intramolecular N→Sn interactions in solid state. The IR spectra suggest an isothiocyanato behavior of the NCS group in solid state in all cases, while the 119Sn NMR spectra gave no clear evidence for such a behavior in solution, as no 14N-119Sn couplings were observed. The single-crystal X-ray diffraction studies revealed molecular species for 7, 8 and 12, while 14 is a ionic compound with [{2-(Me2NCH2)C6H4}2Sn(S2CNMe2)]+ cations and SCN− anions.

Polyanionic Gold-Tin Bonding and Crystal Structure Preference in REAu1.5Sn0.5 (RE = La, Ce, Pr, Nd).

During a systematic search of the RE-Au-Sn (RE = La, Ce, Pr, Nd) ternary phase space, a series of compounds with the general formula REAu1.5Sn0.5 have been identified. These phases can be synthesized by arc melting the elemental metals, followed by annealing. The crystal structures were solved using single-crystal X-ray diffraction, with the composition confirmed by energy-dispersive X-ray spectroscopy. All four compounds crystallize in orthorhombic space group Imma with the CeCu2-type structure. Most notable in these compounds is the polyanionic backbone composed of a single statistically mixed Au/Sn position, which creates a puckered hexagonal bonding network separated by the rare-earth atoms. Electronic structure calculations indicate that the Au 5d bands are dominant in the density of states, while the crystal orbital Hamilton population (-COHP) curves demonstrate Au-Au and Au-Sn interactions, which stabilize the crystal structure. Likewise, a qualitative electron localization function analysis supports the existence of a polyanionic network, and a Bader charge analysis implies anionic character on Au and Sn. The preference for these compounds to adopt the simple CeCu2-type structure is also determined using density functional theory calculations and compared to related compounds to establish a better picture of the unusual behavior of Au in polar intermetallic compounds.

Short-lived Circumstellar Interaction in the Low-luminosity Type IIP SN 2016bkv

Abstract While interaction with circumstellar material is known to play an important role in Type IIn supernovae (SNe), analyses of the more common SNe IIP and IIL have not traditionally included interaction as a significant power source. However, recent campaigns to observe SNe within days of explosion have revealed narrow emission lines of high-ionization species in the earliest spectra of luminous SNe II of all subclasses. These “flash ionization” features indicate the presence of a confined shell of material around the progenitor star. Here we present the first low-luminosity (LL) SN to show flash ionization features, SN 2016bkv. This SN peaked at M V = −16 mag and has Hα expansion velocities under 1350 km s−1 around maximum light, placing it at the faint/slow end of the distribution of SNe IIP (similar to SN 2005cs). The light-curve shape of SN 2016bkv is also extreme among SNe IIP. A very strong initial peak could indicate additional luminosity from circumstellar interaction. A very small fall from the plateau to the nickel tail indicates unusually large production of radioactive nickel compared to other LL SNe IIP. A comparison between nebular spectra of SN 2016bkv and models raises the possibility that SN 2016bkv is an electron-capture supernova.

Theoretical investigation of organotin(IV) complexes of substituted benzohydroxamic acids

The complexing abilities of para-substituted benzohydroxamates to the tin metal center of organotin(IV) ions have been investigated using DFT, since organotin(IV) compounds have been touted as promising anti-cancer agents. We have studied the coordination structures of Sn(IV) complexes (R2SnL2) with organoligands (R = Me, Et, n-Bu) and para-substituted benzohydroxamate ligands (L) so as to study the effect of electron withdrawing (Cl, F, NO2) and electron donating substituents (OCH3, NH2) in the ligand as well as in the alkyl group of the organotin compound. The structures of all the complexes are found to be intermediate between distorted octahedron and bicapped tetrahedron, in agreement with experiment. We have analyzed all the complexes in detail, using their Mayer bond orders, ESP charges, HOMO-LUMO plots and Fukui indices. Of all the complexes, the one having methyl as the alkyl group and the para-amino benzohydroxamate ligand is found to be the most stable. This is owing to the stronger ionic and covalent interaction of Sn(IV) with the para-amino benzohydroxamate ligand and methyl group, respectively.

Antioxidative vs cytotoxic activities of organotin complexes bearing 2,6‐di‐tert‐butylphenol moieties

Two series of organotin(IV) complexes with Sn–S bonds on the base of 2,6‐di‐tert‐butyl‐4‐mercaptophenol (L1SH) of formulae Me2Sn(L1S)2 (1); Et2Sn(L1S)2 (2); Bu2Sn(L1S)2 (3); Ph2Sn(L1S)2 (4); (L1)2Sn(L1S)2 (5); Me3Sn(L1S) (6); Ph3Sn(L1S) (7) (L1 = 3,5‐di‐tert‐butyl‐4‐hydroxyphenyl), together with the new ones [Me3SnCl(L2)] (8), [Me2SnCl2(L2)2] (9) (L2 = 2‐(N‐3′,5′‐di‐tert‐butyl‐4′‐hydroxyphenyl)‐iminomethylphenol) were used to study their antioxidant and cytotoxic activity. Novel complexes 8, 9 of MenSnCl4 − n (n = 3, 2) with Schiff base were synthesized and characterized by 1H, 13C NMR, IR and elemental analysis. The crystal structures of compounds 8 and 9 were determined by X‐ray diffraction analysis. The distorted tetrahedral geometry around the Sn center in the monocrystals of 8 was revealed, the Schiff base is coordinated to the tin(IV) atom by electrostatic interaction and formation of short contact Sn–O 2.805 Å. In the case of complex 9 the distorted octahedron coordination of Sn atom is formed. The antioxidant activity of compounds as radical scavengers and reducing agents was proved spectrophotometrically in tests with stable radical DPPH, reduction of Cu2+ (CUPRAC method) and interaction with superoxide radical‐anion. Moreover, compounds have been screened for in vitro cytotoxicity on eight human cancer cell lines. A high activity against all cell lines with IC50 values 60–160 nM was determined for the triphenyltin complex 7, while the introduction of Schiff base decreased the cytotoxicity of the complexes. The influence on mitochondrial potential and mitochondrial permeability for the compounds 8 and 9 has been studied. It is shown that studied complexes depolarize the mitochondria but don't influence the calcium‐induced mitochondrial permeability transition.

Organotin‐Functionalized Crown Ethers as Ditopic Hosts for Lithium Salts: Synthesis, Structures and Complexation Studies of X3SnCH2[16]‐crown‐5 (X = I, Br, Cl)

The syntheses of the organotin‐substituted crown ethers X3SnCH2[16]‐crown‐5 (2, X = I; 3, X = Br; 4, X = Cl), and the organostannate complex Ph4P[4·Cl] are reported. These compounds are characterized by 1H, 13C, and 119Sn, NMR spectroscopy, elemental analyses, electrospray ionization mass spectrometry, and single‐crystal X‐ray diffraction studies. The solid‐state structure of 2 is characterized by two intramolecular O→Sn interactions, whereas 3 and 4 each contain one intra‐ and one intermolecular O→Sn interactions involving crown ether and water oxygen atoms. The tin atoms are six‐coordinate showing each a distorted octahedral environment. NMR spectroscopic studies indicate that hexacoordination is retained in solution. The compounds 3 and 4 are ditopic hosts for LiBr and LiCl, and have the ability to solubilize these salts in acetonitrile. The preferred selectivity of these compounds containing [16]‐crown‐5 moieties (known to be selective for sodium salts), towards lithium salts is credited to the increased Lewis acidity of the tin atom and hence the strong intramolecular O→Sn interactions.

The influence of temperature on interaction of Sn–Cu–Co–W binders with diamond in sintering the diamond-containing composite materials

The influence of sintering temperature on interaction of Sn–Cu–Co–W metallic binders with diamond for diamond-containing composite materials has been studied. The powdered components of metallic binders and synthetic diamonds AS150 were mixed with the organic binder and applied on a steel base. Sintering was performed in vacuum at 820–1100°C. It has been found out that in the composite materials, tungsten carbide (WC) is formed at sintering temperatures exceeding 900°C. Catalytic phase transformation of diamonds into graphite under the effect of the liquid phase containing dissolved cobalt and tungsten occurs at the same temperatures.

Oxidative dehydrogenation of propane over Pt–Sn/Si-beta catalysts: key role of Pt–Sn interaction

Bimetallic Pt–Sn catalysts supported on dealuminated Si-beta zeolite were prepared via wet impregnation and the nanoscale close contact between Pt and Sn species in Pt–Sn/Si-beta was confirmed by electron microscopy analyses.

Triphenylbismuth(v) di[(iso)nicotinates] - transmetallation agents or divergent organometalloligands? First organobismuth(v)-based silver(i) coordination polymers.

The reaction of Ph3BiCl2 with alkali salts of isonicotinic and nicotinic acids afforded Ph3Bi[O(O)CC5H4N-4]2 (1) and Ph3Bi[O(O)CC5H4N-3]2 (2), respectively, which were characterized by multinuclear NMR spectroscopy in solution, mass spectrometry and IR spectroscopy in the solid state. Their molecular structures were established by single-crystal X-ray diffraction. For both 1 and 2 the molecules contain a trigonal bipyramidal C3BiO2 core, with the phenyl groups in equatorial positions. The potential use of 1 and 2 as ditopic organometalloligands was investigated. The reaction of 1 or 2 with Me3SnCl (1 : 2 molar ratio) resulted in carboxylato ligand exchange and the formation of Me3Sn[O(O)CC5H4N-4] (3) and Me3Sn[O(O)CC5H4N-3] (4) besides Ph3BiCl2. The crystals of both 3 and 4 contain 1-D coordination polymers built through intermolecular N → Sn interactions. The treatment of Ni[S2P(OiPr)2]2 with 1 and 2, respectively, resulted, in addition to di(carboxylato)nickel(ii) derivatives, in isolation of Ph3Bi and the disulphane [(iPrO)2P(S)S]2. New coordination polymers were obtained by reacting 1 and 2 with various silver(i) salts: [Ag{Ph3Bi[O(O)CC5H4N-4]2}(OTf)] (5), [Ag{Ph3Bi[O(O)CC5H4N-3]2}(OTf)]·CH2Cl2 (6·CH2Cl2), [Ag{Ph3Bi[O(O)CC5H4N-4]2}](SbF6)·2THF (7·2THF), [Ag{Ph3Bi[O(O)CC5H4N-3]2}](SbF6)·CH2Cl2 (8·CH2Cl2) and [Ag{Ph3Bi[O(O)CC5H4N-3]2}(NO3)]·CH2Cl2 (9·CH2Cl2). The crystal structures of 5 and 6 can be described as 1-D chains linked by triflate bridges in pairs of chains and 2-D networks, respectively. Compound 7 features a 2-D grid-like topology of the network, with tecton 1 acting as a tridentate ligand through both nitrogen and one oxygen atoms. The linker 2 molecules adopt either cis (compound 6) or trans (compounds 8 and 9) conformation. Complexes 8 and 9 are 1-D chain polymers exhibiting zig-zag and wavy motifs, respectively. The dimensionality of the structures is extended by the presence of supramolecular interactions (ππ, AgAg, AgO).