The recent advancements in wearable exoskeletons have highlighted their effectiveness in assisting humans for both rehabilitation and augmentation purposes. These devices interact with the user; therefore, their actuators and power transmission mechanisms are crucial for enhancing physical human–robot interaction (pHRI). The advanced progression of 3D printing technology as a valuable method for creating lightweight and efficient gearboxes enables the exploration of multiple reducer designs. However, to the authors’ knowledge, only sporadic implementations with relatively low reduction ratios have been reported, and the respective experimental validations usually vary, preventing a comprehensive evaluation of different design and implementation choices. In this paper, we design, develop, and examine experimentally multiple 3D-printed gearboxes conceived for wearable assistive devices. Two relevant transmission ratios (1:30 and 1:80) and multiple designs, which include single- and double-stage compact cam cycloidal drives, compound planetary gearboxes, and cycloidal and planetary architectures, are compared to assess the worth of 3D-printed reducers in human–robot interaction applications. The resulting prototypes were examined by evaluating their weight, cost, backdrivability, friction, regularity of the reduction ratio, gear play, and stiffness. The results show that the developed gearboxes represent valuable alternatives for actuating wearable exoskeletons in multiple applications.
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