Agricultureasaprimaryeconomicactivityisthemajoreconomicbaseoftheworld’spopulation. Agriculture as a primary economic activity is the major economic base of the world’s population. More than 60 percent of the world population depends on agriculture for their livelihood. This study was conducted in Dawuro Zone Essera district achieve the general objective that assessed the impacts of population growth on agricultural production and farming practices. Essera district is 102,848, of whom 51.35% are male and 48.64% are female. This district falls into three agro-ecological regions, of which, kolla within (500-1500masl), weina-dega within (1501-2500 masl) and Dega above (> 2500 masl). To conduct this study, the cross-sectional survey design with the application of both qualitative and quantitative approaches were employed. The study involved a multistage sampling, i.e. a combination of purposive, stratified, and simple random sampling procedures to select the study area and sample households. To draw the samples, the households in the study area, Stratified random sampling technique was applied to collect information from respondents. Study area districts stratified into 3 stratums based on agro ecological zone, after this stratification in agro-ecological zone, kebeles that study has been undergone, selected purposively. That is kola whose elevation ranges from 1000m-1500m above sea level, woynadega whose elevation ranges from 1500m-2000m above sea level, and dega whose elevation ranges from 2000-3000m above sea level. Data that was made available through different instruments was analyzed using quantitative and qualitative techniques. Different tables, maps and figures were also used to illustrate the various aspects of the study. In the light of the theories considered and the finding of the study indicated, both the population pessimistic views of Malthusians and neo Malthusians and the optimistic views of Boserupian could not separately provides the complete explanations regarding the population and agricultural production relationship of this study. It was observed that, increase in population growth of the area associated with an increase in usage of modern inputs which increase in total crop outputs in general and yields for some crop types such as cereals in particular. Moreover, labor intensive land investment practices including tree planting; terracing, manuring croplands were increasingly under taking by peasants as result of rapid change in population size of the area. Farmers have to be advised to plant tree at area far away from land serving agricultural activities.