Intense Activity Research Articles

Overlooked effects of chlorides and bicarbonates on the intensity of peroxydisulfate activation in Fe(II)/citric acid-S2O82− process

The influence of chlorides (Cl−) and bicarbonates (HCO3−) on the Fe(II)/citric acid peroxydisulfate based (Fe(II)/CA-S2O82−) process has been commonly attributed to the formation of secondary reactive species, such as Cl• and CO3•, and their different reactivity with the target pollutant compared to primary reactive species (e.g., SO4•−). However, this conclusion has been entirely based only on analyzing target pollutants removal without the context of S2O82− consumption and dissolved Fe concentration throughout the process. To address this knowledge gap, we conducted a series of batch experiments to investigate the influence of Cl− (2 mmol∙L-1) and HCO3− (1 mmol∙L-1) on the intensity of S2O82− activation within the Fe(II)/CA-S2O82− process with tetrachloroethene (PCE) as the target pollutant. Throughout the experiments, PCE removal efficiency, S2O82− consumption, pH, redox potential, and dissolved Fe were analyzed. Equilibrium hydrochemical modelling (Visual MINTEQ 4) and high-resolution transmission electron microscopy (TEM) were employed to analyze and interpret the data obtained. We found that both Cl− and HCO3− significantly affected the intensity of S2O82− activation. While Cl− influenced the steady-state dissolved Fe(II) concentration, HCO3− primarily increased solution pH, which led to the formation of CA-stabilized ferrihydrite nanoparticles. This resulted in the inaccessibility of dissolved Fe(III) to the Fe(III)/Fe(II) regeneration cycle, consequently suppressing S2O82− activation intensity and PCE removal. Overall, the findings in this study have deepened the fundamental knowledge of how Cl− and HCO3− influence the Fe(II)/CA-S2O82− process, which may help improve the design and operation of S2O82−-based advanced oxidation processes using the Fe(II)/CA activation method.

Prevalence and determinants of low QRS voltages and QRS fragmentation in children and adolescents undergoing sports preparticipation screening.

Low QRS Voltages (LQRSV) in limb leads and QRS fragmentation (FQRS) are possible electrocardiographic signs of myocardial fibrosis and cardiomyopathy, but they are not listed in current criteria for interpretating athlete's ECG. We investigated the prevalence and determinants of LQRSV and FQRS in a cohort of young apparently healthy athletes undergoing preparticipation screening (PPS). We analysed a consecutive series of 2140 ECG obtained during PPS of young athletes (mean age 12.5±2.6 years, 7-18 year-old, 49% males). The peak-to-peak QRS voltage was measured in all limb leads and LQRSV were defined when maximum value was <0.5 mV. Fragmented QRS morphologies were grouped into five patterns. Lead aVR was not considered. Maximum peak-to-peak QRS voltage in limb leads was 1.4±0.4 mV, similar between younger and older athletes, but significantly lower in females than males (1.35±0.38mV vs 1.45±0.42mV; p<0.001). There was a weak correlation between maximal QRS voltages and body mass index (BMI), but not with type of sport or training load. Only 5 (0.2%) individuals showed LQRSV. At least one fragmented QRS complex was identified in 831 (39%) individuals but excluding the rSr' pattern in V1-V2, only 10 (0.5%) showed FQRS in ≥2 contiguous leads. They were older than those without FQRS, but did not differ in terms of gender, BMI, type of sport or training load. LQRSV in limb leads and FQRSV in ≥2 contiguous leads excluding V1-V2 are rare in young apparently healthy athletes and are not related to the type and intensity of sport activity. Therefore, they may require additional testing to rule out an underlying disease particularly when other abnormalities are present.

Development and validation of a generic methyltransferase enzymatic assay based on an SAH riboswitch

Methylation of proteins and nucleic acids plays a fundamental role in epigenetic regulation, and discovery of methyltransferase (MT) inhibitors is an area of intense activity. Because of the diversity of MTs and their products, assay methods that detect S-adenosylhomocysteine (SAH) – the invariant product of S-adenosylmethionine (SAM)-dependent methylation reactions - offer some advantages over methods that detect specific methylation events. However, direct, homogenous detection of SAH requires a reagent capable of discriminating between SAH and SAM, which differ by a single methyl group. Moreover, MTs are slow enzymes and many have submicromolar affinities for SAM; these properties translate to a need for detection of SAH at low nanomolar concentrations in the presence of excess SAM. To meet these needs, we leveraged the exquisite molecular recognition properties of a naturally occurring SAH-sensing RNA aptamer, or riboswitch. By splitting the riboswitch into two fragments, such that SAH binding induces assembly of a trimeric complex, we engineered sensors that transduce binding of SAH into positive fluorescence polarization (FP) and time resolved Förster resonance energy transfer (TR-FRET) signals. The split riboswitch configuration, called the AptaFluor™ SAH Methyltransferase Assay, allows robust detection of SAH (Z’ > 0.7) at concentrations below 10 nM, with overnight signal stability in the presence of typical MT assay components. The AptaFluor assay tolerates diverse MT substrates, including histones, nucleosomes, DNA and RNA, and we demonstrated its utility as a robust, enzymatic assay method for several methyltransferases with SAM Km values < 1 µM. The assay was validated for HTS by performing a pilot screen of 1,280 compounds against the SARS-CoV-2 RNA capping enzyme, nsp14. By enabling direct, homogenous detection of SAH at low nanomolar concentrations, the AptaFluor assay provides a universal platform for screening and profiling MTs at physiologically relevant SAM concentrations.

Metabolic equivalents intensity thresholds for physical activity classification in older adults

BackgroundAlthough the metabolic equivalents (METs) system is a common procedure to quantify the intensity of physical activity in older adults, it remains unclear whether the conventional METs intensity thresholds (CTs) used for this purpose are appropriate in this population. Therefore, this study aimed (i) to derive overall and fitness-specific METs intensity thresholds in older adults ≥ 60 years old (OATs) expressed both in standard METs (VO2/3.5 mL O2·kg−1·min−1) and older adults METs60+ (VO2/2.7 mL O2·kg−1·min−1), and (ii) to compare them with the CTs.MethodsA total of 93 subjects were assessed for cardiorespiratory fitness. Graded exercise test protocols using indirect calorimetry were performed to calculate individual VO2max and categorize subjects as "very poor/fair" or "good/superior" fitness. Overall and fitness-specific OATs expressed in standard METs (OATsstandard) and METs60+ (OATs60+) were derived based on the %VO2max and the ventilatory thresholds (VTs) physical intensity categories.ResultsSignificantly higher VO2max, VO2 at VT1 and VO2 at VT2 (p < 0.001) were obtained in the "good/superior" subgroup compared to the "very poor/fair" fitness subgroup. Accordingly, OATs were approximately 69% higher in individuals with a "good/superior" fitness compared to those with a "very poor/fair" fitness. Furthermore, this study showed that OATsstandard were approximately 21–24% lower than OATs60+, and 10–22% higher OATs were observed when following the VTs intensity categories (heavy-intensity physical activity [HPA] and severe-intensity physical activity [SPA]) compared to the %VO2max categories (moderate-intensity physical activity [MPA] and vigorous-intensity physical activity [VPA]). When compared with the CTs, similar or higher OATsstandard and OATs60+ for MPA, and HPA were obtained compared to the conventional MPA threshold (3.0 METs). Conversely, for VPA and SPA, lower, similar, or higher OATs were obtained depending on the METs derivation approach (OATsstandard or OATs60+) or the intensity categories (VO2max or VTs), compared to the conventional VPA threshold (6.0 METs).ConclusionsNone of the derived OATs were concurrently similar to the CTs, suggesting that fitness-specific METs intensity thresholds adapted to the METs derivation approach should be used in older adults.Trial registrationFenotipAGING (Non-health-care intervention study), PRO-Training (NCT05619250).

Orbital global change drove fluvial aggradation and incision in Tibetan upper Mekong river: Chronological perspectives

The Tibetan Plateau (TP), often known as the “Asia Water Tower”, is the source region of several continental-scale rivers. However, due to the extremely difficult access and harsh living conditions in the interior plateau, fluvial processes in the headwaters of these large rivers and their connections to global climate changes remain unknown. In this study, the luminescence (using both quartz and K-feldspar) and AMS 14C dating techniques were employed to date the four terraces of the Zado Basin in order to elucidate the aggradation and incision history of the initial intermontane basin in the headwater of the Mekong River. One sample from the upper part of T4 terrace (which features a 12 m thick gravel layer, the base of which is unexposed) provides a K-feldspar pIR50IR225 age of 125 ± 10 ka, indicating that the initial deposition of this terrace could predate marine isotope stage (MIS) 5. Considering the margin of error, this age also suggests that the onset of incision on T4 terrace during the climate transition from MIS 6 (glacial) to early MIS 5 (interglacial). This incision likely occurred due to increased meltwater and precipitation, causing the Mekong carving into the bedrock for more than 50 m. Eight luminescence samples are collected from T3 terrace (26.5 m in thickness) with ages ranging from 83 ± 7.6 ka to 22.3 ± 1 0.2 ka, indicating T3 formation/aggradation from late MIS 5 to the Last Glacial Maximum (LGM), possibly owing to reduced precipitation and enhanced sediment supply from intensive glacial activities. At around 22 ka, the Mekong once again shifted towards incision, crafting the T3 terrace, situated roughly 28 m above the current floodplain. This incision event was recorded by two luminescence samples from a sandy lens located at the top of gravel layer of T3, with OSL ages of about 22 ka. Floodplain samples from T2 and T1, dated at 16 ka and 2.8 ka respectively, demonstrate that from the last deglaciation to the Holocene, the Mekong continued its downward incision. This erosion developed two cut and fill terraces at elevations of 22 m and 11 m above the present floodplain, likely due to increased precipitation and enhanced vegetation at that time. Overall, the glacial–interglacial climate changes were the most likely driving force behind fluvial processes in the upper Mekong basin since the Late Pleistocene, with aggradation occurring during the glacial period while incision in deglacial and interglacial periods, suggesting a close link between the fluvial geomorphic evolution and orbital-scale climate changes.

Quantification of Bed Load Transport in the Northern Part of the Central Plateau of Morocco: Case of Wadi Skhirate

Rivers play a vital role in our ecosystems, providing fresh water, supporting rich biodiversity, and contributing to human well-being. However, in the face of climate change and intensive human activities, the sediment load in rivers can reach critical levels, presenting a complex set of challenges that require immediate action. The increased sediment load can alter aquatic habitats, clog channels, reduce reservoir storage capacity, and increase the risk of flooding. These direct threats entail high costs in terms of material and ecological damage, loss of life, and expenditure on rebuilding damaged infrastructure. The quantification of bedload in watercourses is therefore crucial for maintaining water and soil resources, safeguarding riparian communities, and preserving ecological balance. The study reports the findings of a three-year monitoring of the bed load of Skhirate Wadi, a river that drains a part of the western Moroccan Meseta. The study used the colorimetric monitoring method, which quantifies the volumes of coarse sediment that were transported by monitoring topographic variations in the riverbed and measuring the distances covered by the sediment. The study showed the sediment was found to move around seven times annually on average. However, the frequency and magnitude of floods and the size of particles affect the variation in this displacement. It also showed sediments travel an average distance ranging from 649 to 883 meters per year, and that the average specific bedload at the watershed scale is 30 m3/ Km2/ year. Relationships between flood peaks mobilized sediment volumes, and average particle distances are established and discussed. These results are fundamental to understanding of coarse sediment transfer processes in the small rivers of the central plateau. They are also essential for assessing the impact on the aquatic ecosystem, on downstream dams, and on the various existing road and hydro-agricultural infrastructures. This assessment will enable the implementation of appropriate management strategies to anticipate changes and plan the planning of the river and its watershed.

Visitation-based classification of urban parks through mobile phone big data in Tokyo

Urban parks, pivotal in fostering physical activity, mental well-being, and environmental stewardship, are integral to green infrastructure planning. Despite advances in georeferenced data applications, existing park classifications often overlook actual visitation patterns. This study reclassifies urban parks using over 5.9 million records from approximately 330 thousand visitors across 300 Tokyo parks, comparing with size-based park categorizations. We employed a range of analytical tools, including principal component analysis, Isolation Forest algorithm, various clustering algorithms, and the Gini index. Our findings first revealed four key visitation indicators, activity intensity, utilization efficiency, temporal occupancy, and revisit volume. These indicators uncovered parks with atypical visitation patterns within each size category, leading to three novel park classifications, everyday leisure parks, social destination parks, and seasonal activity parks. Moreover, we discovered notable disparities in distances traveled to parks, particularly during nights, weekends, and holidays, with pronounced inequalities in seasonal activity parks and smaller parks. The findings advocate for a nuanced park management strategy, prioritizing maintenance and amenity development aligned with observed visitation patterns to enhance recreational potential, thereby contributing insights to urban park research that support the advancement of green infrastructure planning and policy aimed at improving park utility and enjoyment.

Evaluating the association between lifetime physical activity and oral squamous cell carcinoma: A case-control study.

Oral cancers are the 6th most common malignancy worldwide and oral squamous cell carcinoma, comprises over 90% of oral cancers. This study investigates the relationship between physical activity level during the lifetime and oral squamous cell carcinoma risk. 100 oral squamous cell carcinoma patients and 200 healthy individuals participated in this case-control study. Physical activity level was evaluated via the Lifetime Physical Activity Questionnaire. The occupational, household, and sports domains of lifetime physical activity were determined. Case and control groups' participants were matched in terms of sex, age, smoking, and alcohol consumption by the Frequency Matching Method. Mann-Whitney U Test was applied to compare physical activity levels between groups. The Body Mass Index was higher among cases compared with controls. The average amounts of lifetime physical activity among cases and controls were approximately identical. However, only a statistically significant difference between time spent on total lifetime physical activities and the oral squamous cell carcinoma risk was discovered. Moreover, there were no statistically significant odds ratios in examining the risk associated with each domain of activities. The total time spent on lifetime physical activity may decrease the risk of oral squamous cell carcinoma; However, the total level and intensity of lifetime physical activity are not significantly associated with the oral squamous cell carcinoma risk. Further studies are required in this field.

Effects of Breaking up Sitting on Gut Hormone Responses and Subsequent Compensatory Behaviours in Physically Inactive Adults.

The effects of breaking up sitting on gut hormone responses and free-living energy compensatory behaviours are still unclear in people of Asian ethnicity. 26 Asians including 13 lean individuals (Lean) and 13 individuals with centrally overweight/obesity (OW), aged between 20 to 45 years, completed a randomized crossover study with either 5.5-h uninterrupted sitting (SIT) or 5.5-h sitting with 2 min walking at 6.4 km/h every 20 min (ACTIVE) in the laboratory. Blood samples were collected at regular time-points to examine postprandial glucagon-like peptide 1 (GLP-1), peptide YY (PYY) and glucose-dependent insulinotropic polypeptide (GIP) concentrations. Free-living physical activity and energy intake were recorded using wearable devices and weighed food diaries outside the laboratory until midnight. Paired t-tests were conducted to compare responses between trials. Postprandial GLP-1 and PYY incremental area under curve values were higher in the ACTIVE trial versus SIT in both Lean and OW groups (all, p < 0.05), but there was no difference in GIP in either group (both, p > 0.05). There were no differences in free-living physical activity (volume and intensity) or energy intake (total and macronutrients) between trials in either group (all, p > 0.05), resulting in greater total physical activity over the 24-h monitoring period in ACTIVE trial versus SIT trial (both, p < 0.05). Breaking up sitting increases postprandial GLP-1 and PYY concentrations in Asians, but does not induce subsequent behavioural compensation, resulting in greater 24-h physical activity levels and lower relative energy intake, in inactive individuals irrespective of bodyweight status.

Timing Matters: A Longitudinal Study Examining the Effects of Physical Activity Intensity and Timing on Adolescents' Mental Health Outcomes.

Physical activity is universally acknowledged for its benefits to mental health; however, the specific intensities and timings that best benefit adolescents' mental health, crucial due to their significant influence on daily schedules, have not been thoroughly investigated. This study addresses the substantive research gap by exploring the varied effects of physical activity intensity (light versus moderate to vigorous) and timing (weekdays versus weekends and holidays) on adolescent mental health. Utilizing a large-scale longitudinal dataset (NT1 = 84,054; NT2 = 44,623) from 158 schools, this research describes the current state of adolescent physical activity and investigates the effects of physical activity on mental health outcomes, including positive (i.e., life satisfaction, positive mental health) and negative indicators (depression, anxiety), over a 6-month period. Participants were adolescents aged 9-19 years (mean age = 12.73 ± 2.43 years, 48.9% female), with the analysis adjusted for potential confounding factors. Results showed that as adolescents grow older, their engagement in moderate-to-vigorous physical activity during both weekdays and weekends/holidays tends to decrease, while light physical activity during weekdays increases. Multilevel regression analysis indicated that moderate-to-vigorous physical activity during weekends/holidays at Time 1 positively correlated with better mental health outcomes at Time 2 (six months later), featuring enhanced positive indicators and reduced negative ones. Moderate-to-vigorous physical activity on weekdays at Time 1 was positively linked to mental health at Time 2. Light physical activity during weekends/holidays at Time 1 positively predicted life satisfaction and positive mental health at Time 2. In contrast, light physical activity on weekdays at Time 1 negatively correlated with life satisfaction at Time 2. The study underscores the importance of promoting moderate-to-vigorous physical activity, particularly on weekends and holidays, to improve mental health outcomes among adolescents.

Changes in the limiting nutrients and dominant phytoplankton communities of three major European rivers: Response to catchment lithologies and human activities

Catchment lithologies and human activities can cause variations in riverine carbon (C), nitrogen (N), and phosphorus (P) loads, and the ratio of these nutrients may affect the primary productivity of rivers and their phytoplankton communities. We conducted a comparative study of biogeochemical variations in three major European rivers—the Rhine, Danube, and Seine—which reveals the impacts of different carbonate outcrops and human impacts (agricultural activities and sewage input) on the changes in the limiting nutrients and phytoplankton community compositions of flowing water systems. N limitation was observed in the Rhine and Danube owing to their low average NO3– loads (4.04–6.45 mg/L). Although the extensive outcrops of carbonate rocks in the Seine catchment result in high average HCO3– concentrations of ∼ 4.68 mmol/L, the elevated inorganic C input did not match the high average NO3– loads (∼19.38 mg/L), driven by intensive agricultural activity and urban sewage input, demonstrating a potential C limitation on productivity. Our results show that the productivity of the Seine River, determined by the chlorophyll-a concentration, was significantly related to the dissolved inorganic carbon (DIC) concentration (coefficient of determination: R2 = 0.68, P < 0.05). Our results demonstrate that changes in DIC content can significantly alter the dominant phytoplankton species in the water column. The high inputs of DIC and aqueous CO2(aq) to the Seine lead to Bacillariophyta proportions that are 3.96–8.81 % and 19.87–22.56 % higher than those of the Rhine and Danube in the wet and dry seasons, respectively. This can be explained by the difference in the efficiency of carbon concentrating mechanisms (CCMs) among phytoplankton species. Therefore, to mitigate river eutrophication and improve the quality of the aquatic environment, we suggest that future water–carbon management in the flowing water systems with abundant nutrients should consider C-limitation alleviation and its potential effect for reducing the abundance of harmful algae.

Early Holocene inundation of Doggerland and its impact on hunter-gatherers: An inundation model and dates-as-data approach

Sea-level rise was a key factor changing environments during the Early Holocene in Northwest Europe. It affected Mesolithic hunter-gatherer communities by inundating large areas in the current North Sea, commonly referred to as Doggerland. In this paper we present novel inundation models for the southern North Sea providing visualisations of lateral inundation driven by sea-level rise and relate it to frequency analysis of radiocarbon dates from archaeological sites. These improve on previous studies that relied on bathymetric data, which includes post-inundation overprints of Holocene sedimentation and erosion, and thus significantly underestimates the timing of inundation in some areas.We constructed a paleoDEM (a composite elevation grid of the top of the Pleistocene) for the eastern part of the southern North Sea; and sea level surfaces that combine relative sea-level curves from glacio-isostatic adjustment models optimised for Britain and southern Scandinavia respectively. We corrected our paleoDEMs for tectonic background basin subsidence, and in the inundation modelling account for pre-compaction elevation of peat in coastal areas. We evaluated the impact of these model components on our results and describe the possible inundation history of Doggerland. We suggest earlier inundation than predicted by previous models, showing significant area loss around 10.5–10 ka cal BP.Palaeogeographic changes are compared with archaeological radiocarbon data using a dates-as-data approach. Composite Kernel Density Estimate and permutation tested Summed Probability Distributions are used as a proxy for the visibility, nature and intensity of human activity. Results indicate key periods of growth and decline recorded in the dataset, as well as regional differences in growth rate, some correlating with inundation phases. Chiefly, we find elevated growth rates around 10.5–10 ka in northwest Germany and the Netherlands, contemporaneous with the abovementioned phase of extensive area loss, and moreover, with changes in culture and practices on Early Mesolithic sites.However, the spatiotemporal distribution of archaeological data is significantly influenced by accessibility and preservation of sediments of a certain age. We discuss the importance of inundation modelling and sediment data in understanding how landscape taphonomy affects archaeological patterning, especially in dates-as-data approaches.

Comparison of Fruit Texture and Storage Quality of Four Apple Varieties.

Fruit texture and storage properties of various apple varieties exhibit significant variation. The rate of fruit softening post-harvest plays a crucial role in determining fruit quality and shelf life. This research utilized four apple varieties as test subjects to investigate the internal factors influencing fruit texture changes among different varieties. By monitoring changes in relevant physiological indicators during the post-harvest texture softening process, the study examined fruit quality, cell wall material content, hydrolase activity, and gene transcription levels during storage of 'Orin', 'RX', 'RXH', and 'Envy' apples. Initial fruit softening was primarily linked to heightened post-harvest fruit respiration intensity, ethylene production, and rapid amylase activity. Subsequent softening was associated with increased activity of water-soluble pectin (WSP), cellulose (CEL), and other hydrolases. With the extension of the storage period, the fruit cells of the four varieties became more loosely arranged, resulting in larger intercellular gaps. Variations in WSP and cellulose content, CEL activity, and relative expression of Mdβ-gal were observed among the different apple varieties, potentially accounting for the disparities in fruit texture.

Spatiotemporal dynamic evolution and influencing factors of land use carbon emissions: evidence from Jiangsu Province, China

Land use/cover change has an important impact on global climate change and carbon cycle, and it has become another major source of carbon emission after energy consumption. Therefore, this study focuses on the main line of “land use carbon emissions-spatial and temporal patterns-influencing factors,” and selects 13 cities in Jiangsu Province as the research object. Based on the data of land use and energy consumption, combined with the method of land use carbon emissions and ArcGIS technology, this study conducted a quantitative analysis of the spatio-temporal distribution of carbon emissions in Jiangsu Province. The factors affecting the spatial distribution of carbon emissions from land use in Jiangsu Province were discussed by using Geographic detector. The results show that: 1) Carbon emissions in Jiangsu Province showed an overall growth trend, from 16215.44 ×104tC in 2010–23597.68 ×104tC in 2020, with an average annual growth rate of 4.55%, of which the construction land and watersheds had a greater impact on carbon sources and sinks, respectively. 2) During the period, there were significant differences in carbon emission levels among different cities in Jiangsu Province, and the land use carbon emission in Jiangsu Province showed a stable spatial pattern of “northwest—southeast.” The southern part of Jiangsu is always the hot area of carbon emission, while the cold spot area is mainly distributed in the northern and central parts of Jiangsu. 3) The interaction of factors such as economic development, industrial structure, energy intensity, land use and human activities is an important reason for the spatio-temporal differences of land use carbon emissions in Jiangsu Province. Among them, the level of urbanization, population size and economic aggregate have significant effects on carbon emissions.

Measuring Physical Activity in Children Who Do Not Walk and With Cerebral Palsy: An Exploratory Case Series.

The purpose of this case series was to describe physical activity (PA) amount and intensity in the home and school environment. Accelerometers and heart rate (HR) monitors are reliable and valid measures of PA in children with cerebral palsy (CP) who can walk. There is limited research on PA measures in children with CP who cannot walk. Three 9-year-old boys with CP, Gross Motor Function Classification System levels IV and V, participated in a 1-week measurement period wearing waist- and wrist-worn triaxial accelerometers to measure PA counts and a wrist-worn HR monitor to measure PA intensity. PA intensity was calculated using an estimated HR max. Accelerometer counts were reported. Parents and school staff completed activity and eating journals. Six days of PA and HR data were analyzed. Two participants spent more time in moderate/vigorous PA intensity during school compared to at home. Activities with greatest PA intensity included oral eating, communication, and social engagement. Higher activity counts were recorded from the wrist compared with the waist accelerometers. PA and eating journal adherence were high in both settings. The findings provide preliminary data to evaluate PA amount and intensity in children with CP who have little walking ability. It is important to consider PA levels in daily activity for youth with CP when designing plans of care.

Peisistratus' exiles and the strategic international network

AbstractFrom ancient sources, we learn that typically, a politician condemned to exile would withdraw to private life, waiting for the period of interdiction to end. For Pisistratus, on the contrary, sources tell us that during his exiles, he distinguished himself by conducting intense activity, both politically and economically.My contribution aims to demonstrate, in particular, how the periods of exile were exploited by the future tyrant of Athens to intensify his expansionist activity. The fruits of this activity, detached from the actions of the city and configured as a ‘private' initiative, were made available to the entire citizenry upon ‘return' to the city and proved to be particularly valuable for the growth of the city of Athen.

Physical activity levels of pregnant women at the time of diagnosis with gestational diabetes attending a tertiary care hospital in Lucknow City, Uttar Pradesh

: Gestational Diabetes Mellitus (GDM) is one of the pregnancy complications characterized by carbohydrate intolerance that develops or is discovered during pregnancy. Physical inactivity and excessive gestational weight gain have been identified as independent risk factors for maternal obesity and pregnancy-related disorders, such as gestational diabetes. Awareness of the significance of physical activity for bodily and psychological health is vitally essential. The woman and her family members need to be swayed to change with time and let go of their myths and false cultural perceptions that exercise can harm the baby. : To determine the physical activity pattern of pregnant women at the time of diagnosis with GDM. : 188 pregnant women diagnosed with gestational diabetes mellitus was selected for the study. Pregnancy Physical Activity Questionnaire was used to calculate the duration; frequency, intensity, and type of physical activity during current gestational period. An average weekly energy expenditure in Metabolic Equivalent of Task (MET-h-week) was calculated. Demographic data including age, socioeconomic status, parity, literacy and working status were collected. Data was analysed on 188 pregnant women diagnosed with GDM. The physical activity of moderate intensity was less performed by the pregnant women. None of the pregnant women were involved in vigorous type of physical activity. Only light intensity activities were performed by the study participants. The study concluded light intensity activity was commonly carried by pregnant women thus a low level of physical activity was observed during the pregnancy.

The influence of perceived stress and motivation on telomere length among NCAA swimmers.

Telomere length (TL) shortening is associated with increased cellular senescence and functional decline with age. Regular physical activity is posited to safeguard against TL shortening, but there is disagreement on how concurrent psychosocial stress may influence this relationship. The current analysis explored whether psychosocial stress is associated with TL differences in highly physically active individuals. TL was measured from capillary dried blood spots collected from Division-I (D-1) and Division-III (D-3) National Collegiate Athletics Association (NCAA) swimmers (N = 28) and non-athlete students from the same schools (N = 15). All participants completed Cohen's Perceived Stress Scale (PSS) and student-athletes completed an additional questionnaire to assess psychosocial factors associated with their lifestyle; The Student Athletes' Motivation towards Sports and Academics Questionnaire (SAMSAQ). Semi-structured interviews further contextualized how student-athletes internalize their stress. There was no significant difference in TL or PSS scores between swimmers and controls. D-1 swimmers reported significantly higher career and student-athlete motivation scores compared to D-3, but non-significantly higher PSS and similar academic motivation scores. Themes from interviews with collegiate swimmers included COVID-19 stress, fear of injury, pressure from academics, expectations to perform, and financial pressures. These themes may have contributed to higher PSS scores in D-1 swimmers compared to D-3 but did not appear to impact their TL. Given differences in perceived stress, sources of stress, and SAMSAQ scores, further analyses with larger sample sizes are needed to better understand how these factors influence human biology and health while engaged in intense physical activity.

STATUS PEMANFAATAN IKAN KAKAP (Lutjanus spp.) BERBASIS DATA PANJANG IKAN DI PERAIRAN TAMAN NASIONAL TAKA BONERATE

Snappers (Lutjanus spp.) are the most common reef fish caught in Taka Bonerate National Park due to its high economic value and primarily targeted species. Without proper management measures, intensive fishing activities might result in unsustainable fish stocks. Therefore, in order to maintain sustainable utilization, it is important to understand the stock status of snapper fisheries. This study aimed to analyze the snappers' stock status in Taka Bonerate National Park's waters. Data were collected from January to December 2022 at three small-scale fisheries landing sites. The results showed that snappers are classified as slow-growing species with growth rates for species L. bohar, L. quinquelineatus, L. gibbus respectively 0,12, 0,39, and 0,35 per year to reach their respective asymptotic lengths of 83,41 cm, 29,5 cm, and 46,80 cm. The stock status of L. gibbus and L. bohar were indicated at overfished status where the exploitation rate (E) was &gt; 0.5 and the SPR was &lt; 0.3, hence a proper management measures is required. Furthermore, the species of L. quinquelineatus has a value of E is 0.5 and SPR is at 0.3, indicating that the utilization level of this species was at an optimal level. Keywords: Snapper, Taka Bonerate, Fisheries Management.

Assessment of particulate Zn and Pb sources in the Orne watershed (Northeast France) using geochemical tools.

The Orne River, a tributary of the Moselle River, was highly impacted by industrial activities for more than one century. Land use along the Orne River is highly contrasted, with local specificity from its source to its junction with the Moselle River. The intense industrial activity left behind tons of steelmaking wastes (SMW) on the land surface and within the Orne riverbed. To assess the sources of particulate Zn and Pb transported as suspended sediment in the Orne River, different sets of samples from likely Zn- and Pb-bearing particle sources within the Orne watershed were collected. Three sets of samples were taken from potential sources representing detrital, urban, and inherited industrial particles. Mineralogy, element contents, and Zn and Pb isotope compositions were obtained to characterize and reveal the fingerprint of each set of samples. Soil samples were collected on distinct geomorphological areas characterized by different soil types and land uses. They all display detrital minerals assigned to the geological background. Urban dusts and steelmaking residues display specific mineral phases (sulfates and iron oxides, respectively). Element compositions present strong discrepancies between the distinct sets of samples. SMWs are particularly enriched in Fe, Zn, and Pb. Concerning isotopic composition, SMWs exhibit δ66Zn values ranging from - 0.67 to 1.66‰. Urban samples display δ66Zn values between - 0.11 and 0.13‰, and soils present δ66Zn values between - 0.24 and 0.47‰. The 206Pb/204Pb ratio was estimated to range from 17.550 to 18.807 for soils, from 17.973 to 18.219 for urban samples, and from 18.313 to 18.826 for SMWs. For each of the three sets of samples (soils, urban, industrial), variations of geochemical fingerprint were observed. For soils, the relatively large variations of Zn and Pb isotopic compositions were attributed to distinct land use and the contribution of atmospheric deposition. For industrial samples, the variations were more intense and may be attributed either to distinct industrial processes in the production of pig iron or to distinct furnace-flume treatment modes. The three sets of samples (urban, industrial, and detrital) could be distinguished based on Zn and Pb contents and isotopes. Finally, this study not only highlighted the sources that released particulate Zn and Pb into the Orne River system, it also demonstrated that urban particles are well defined in terms of Zn and Pb isotopic signatures, and those isotopic signatures could be extrapolated to other case studies.