The performance of high-speed intensity modulation direct detection (IM-DD) transmissions is severely degraded by the linear inter-symbol interference (ISI), due to both bandwidth-constrained optoelectrical components and the chromatic dispersion (CD). Meanwhile, nonlinear ISI due to intensity modulation and square-law detection can further deteriorate the IM-DD system performance significantly. Here, we first propose three metrics to quantify those impairments in IM-DD transmissions. Then, we compare both the BER performance and computational complexity of different DSP schemes to enable short-reach high-speed IM-DD transmissions with severe bandwidth constraint, using a C-band PAM-4 experimental test-bed with an end-to-end 10-dB bandwidth of 17 GHz. Those DSP schemes include receiver-side feedforward equalization (FFE), receiver-side Volterra filter equalization (VFE), transmitter-side Tomlinson-Harashima precoding (THP) together with receiver-side FFE, transmitter-side THP together with receiver-side VFE, channel-shortening filter (CSF) together with maximum likelihood sequence estimation implemented with linear branch metrics (MLSE-LI-BM), and CSF together with MLSE implemented with nonlinear branch metrics (MLSE-NL-BM). Our experimental results indicate that, only the combination of CSF and MLSE-NL-BM enables a 112 Gbit/s transmission over 5 km fiber at the KP4-FEC threshold, but with an increased computational complexity.