In recent years, the emergence of Cyber-Physical systems (CPS), big data, cloud computing, and industrial wireless networks have promoted the development of Industry 4.0. Intelligent manufacturing systems are the leaders of this change. In smart manufacturing, the emphasis will be placed on using technologies such as big data analytics, cloud computing, edge computing, and artificial intelligence (AI). The advantages of new technologies are significantly reflected in the comparison of preventive maintenance and traditional maintenance based on intelligent technology: preventive maintenance significantly reduces the cost of prevention and, at the same time, dramatically improves the accuracy and timeliness of maintenance, bringing inestimable value to intelligent manufacturing. This paper will analyze new technologies’ innovative advantages and technical prospects through big data analysis and specific application scenarios of AI technology in preventive maintenance. Firstly, in data acquisition, this paper examines the architecture of preventive maintenance systems based on big data. Then, it analyzes the composition of the data pipeline: in the realization of data collection and processing in the field of cloud computing and edge computing, and the aspect of data processing, it discusses the participation of AI technology in data understanding and processing and the unprecedented changes it brings.