The intercession of Health, Safety, and Environmental (HSE) risk assessments with public health strategy is crucial in mitigating occupational hazards and controlling the spread of infectious diseases. This review examines the role of Health, Safety, and Environment (HSE) risk assessments in mitigating occupational hazards and controlling the spread of infectious diseases, with a focus on public health implications. The study highlights the importance of comprehensive risk assessments in identifying and managing workplace hazards, including both physical and psychosocial risks. It discusses the integration of advanced technologies, such as artificial intelligence and big data analytics, to enhance the predictive capabilities of HSE risk assessments. The review also explores the necessity of ethical considerations in the application of these technologies, emphasizing transparency, privacy, and accountability. Furthermore, it underscores the importance of coordinated efforts between industries and public health authorities, especially in the context of infectious disease outbreaks like COVID-19. Policy recommendations include the development of robust regulations, the promotion of industry-public health collaboration, and the provision of support for small and medium-sized enterprises. The review identifies gaps in current research and suggests future directions, such as longitudinal studies on the effectiveness of HSE interventions and the inclusion of psychosocial factors in risk assessments. By addressing these gaps and implementing the proposed recommendations, policymakers and industry stakeholders can significantly enhance workplace safety and health standards, ultimately protecting workers and promoting public health resilience.