Integration Of Other Materials Research Articles

Nanoscale 3D spatial addressing and valence control of quantum dots using wireframe DNA origami

Control over the copy number and nanoscale positioning of quantum dots (QDs) is critical to their application to functional nanomaterials design. However, the multiple non-specific binding sites intrinsic to the surface of QDs have prevented their fabrication into multi-QD assemblies with programmed spatial positions. To overcome this challenge, we developed a general synthetic framework to selectively attach spatially addressable QDs on 3D wireframe DNA origami scaffolds using interfacial control of the QD surface. Using optical spectroscopy and molecular dynamics simulation, we investigated the fabrication of monovalent QDs of different sizes using chimeric single-stranded DNA to control QD surface chemistry. By understanding the relationship between chimeric single-stranded DNA length and QD size, we integrated single QDs into wireframe DNA origami objects and visualized the resulting QD-DNA assemblies using electron microscopy. Using these advances, we demonstrated the ability to program arbitrary 3D spatial relationships between QDs and dyes on DNA origami objects by fabricating energy-transfer circuits and colloidal molecules. Our design and fabrication approach enables the geometric control and spatial addressing of QDs together with the integration of other materials including dyes to fabricate hybrid materials for functional nanoscale photonic devices.

All chemical solution deposition of epitaxial porous BiFe0.93Mn0.07O3 thin films

BiFeO3 as a type of single-phase room temperature multiferroic materials has aroused intensive investigations in recent years. Construction of porous BiFeO3 thin films is helpful for integration of other materials with desirable functionalities. Here, epitaxial BiFe0.93Mn0.07O3 (001) thin films were prepared on SrRuO3-buffered LaAlO3 (001) single crystal substrates by an all-solution chemical solution deposition, which is beneficial for large area thin film fabrication with low cost. Through addition of F-127 copolymer into the precursor solution, pores can be effectively introduced in BiFe0.93Mn0.07O3 (001) thin films while the epitaxy can be maintained. The amount of pores is gradually increased with increasing of the F-127 addition. The leakage current density is not obviously changed and the conduction mechanism can be well fitted through Ohmic behavior. Electric field dependent polarization hysteresis loops can be effectively maintained and the room temperature magnetic moment is obviously improved with the introduction of pores in epitaxial BiFe0.93Mn0.07O3 (001) thin films. The results will provide a facile route to fabricate large area epitaxial porous BiFeO3 thin films as an effective template for integration of other materials to realize desirable functionalities.

Nanopillar-Based Light Emitting Diodes

Daily life is surrounded by the use of optoelectronics in order to provide illumination for the most basic of routines. For this reason, research into the performance enhancement of such optoelectronic devices is paramount in order to understand methods of improving efficiency and thus conserving energy and resources. This review briefly summarized various techniques to fabricate nanopillars for enhancing performance of light emitting diode (LED), using etching masks, nanosphere lithography, integration of other materials, and MOVPE manipulation.

Heterogeneous Nonlinear Integrated Photonics

Integrated photonics has been pursued on a large variety of materials and platforms over more than half a century. In recent decades, silicon has emerged as the preferred optical and substrate material. However, since many optical functionalities cannot be, inherently or conveniently, implemented on silicon-based devices, heterogeneous integration of other materials has been an inevitable constituent of silicon photonics from its inception. This paper reviews recent progress in the heterogeneous integration of dielectrics and compound semiconductors as the core optical material for ultracompact nonlinear integrated photonics, preferably on silicon substrates. Occasionally, important devices on native substrates of the core nonlinear material are also reviewed. The focus is on ultracompact photonic devices and circuits formed on submicron films of lithium niobate (LiNbO3), and the aluminium-gallium-arsenide (AlGaAs) and aluminium-gallium-nitride (AlGaN) families for second-order nonlinear processes, such as second-harmonic generation, and techniques to address phase-matching in them. Integration of second- and third-order nonlinear devices on the same chip appears to be a future trend, thus the related preliminary results are reviewed. A broader introduction to heterogeneously integrated photonics, shortcomings of conventional silicon photonics for application in nonlinear optics, as well as an overview of modeling second-order nonlinear integrated-waveguide devices are also provided for completeness.

Integrated Silicon Photonic Microresonators: Emerging Technologies

Silicon photonics is becoming the leading technology for photonic integrated circuits (PICs) due to large-scale integration, low cost, and high-volume productions enabled by complementary metal-oxide-semiconductor (CMOS) fabrication process. Thanks to various material and optical characteristics of crystalline silicon, the silicon-on-insulator platform has become the dominant material platform for silicon photonics. Meanwhile, monolithic or heterogeneous integration of other materials on silicon photonic chips, including the silicon nitride (SiN)-on-insulator platform and the III–V-on-silicon platform, are under rapid developments to enhance the functionalities of silicon photonics. Among the myriad of silicon photonic structures for passive and active components, integrated microresonators are promising for a broad range of applications due to their strong resonance field enhancement, narrowband wavelength selectivity, and compact footprints. In this paper, we review the state of the art and our perspectives on emerging technologies based on integrated silicon photonic microresonators in the technology domains of intradatacenter optical interconnects, integrated nonlinear and quantum photonics, and lab-on-a-chip optical biosensing. We specifically review recent progress and our original work in SOI microring-based crossbar switch fabrics; III–V-on-silicon microresonator lasers; silicon-based microresonator nonlinear and quantum sources; and SiN microresonator-based optical biosensors.

Fused Deposition Modeling 3D Printing for (Bio)analytical Device Fabrication: Procedures, Materials, and Applications.

In this work, the use of fused deposition modeling (FDM) in a (bio)analytical/lab-on-a-chip research laboratory is described. First, the specifications of this 3D printing method that are important for the fabrication of (micro)devices were characterized for a benchtop FDM 3D printer. These include resolution, surface roughness, leakage, transparency, material deformation, and the possibilities for integration of other materials. Next, the autofluorescence, solvent compatibility, and biocompatibility of 12 representative FDM materials were tested and evaluated. Finally, we demonstrate the feasibility of FDM in a number of important applications. In particular, we consider the fabrication of fluidic channels, masters for polymer replication, and tools for the production of paper microfluidic devices. This work thus provides a guideline for (i) the use of FDM technology by addressing its possibilities and current limitations, (ii) material selection for FDM, based on solvent compatibility and biocompatibility, and (iii) application of FDM technology to (bio)analytical research by demonstrating a broad range of illustrative examples.

Drug delivery systems based on nucleic acid nanostructures

The field of DNA nanotechnology has progressed rapidly in recent years and hence a large variety of 1D-, 2D- and 3D DNA nanostructures with various sizes, geometries and shapes is readily accessible. DNA-based nanoobjects are fabricated by straight forward design and self-assembly processes allowing the exact positioning of functional moieties and the integration of other materials. At the same time some of these nanosystems are characterized by a low toxicity profile. As a consequence, the use of these architectures in a biomedical context has been explored. In this review the progress and possibilities of pristine nucleic acid nanostructures and DNA hybrid materials for drug delivery will be discussed. For the latter class of structures, a distinction is made between carriers with an inorganic core composed of gold or silica and amphiphilic DNA block copolymers that exhibit a soft hydrophobic interior.

The making of a muscle

The skeletal musculature is usually thought of as the primary organ of locomotion, and, like the tyres of a high-performance racing car, their composition, design, preparation and plasticity can make the difference between winner and 'wannabe'. The similarities do not end there, however. Their primary components (cells of the mesodermal layer in the embryo and latex from the rubber tree) begin their existence in locations that can be quite distant from their final point of use and in forms that bear no resemblance to the final product. Their differentiation from primary material to final product entails extensive processing, and the integration of other materials and structures are essential to ensure their function. A fundamental difference, however, is that, in the case of muscle, once the embryo is formed, the progression from relatively undifferentiated mesodermal cells to the final structures is on autopilot, provided there are no contextual aberrations either from genetic or environmental causes. Our current understanding of how muscles develop is a synthesis of observations made on a wide array of organisms, including nematode worms, fruitflies, fish, frogs, birds and various mammals, as well as from the in vitro study of cells isolated from these species. The study of myogenesis in mammals, although less amenable to experimental manipulation, has been facilitated by the recent advances in mouse genetic engineering which has enabled the function of individual genes and cell types to be investigated, as well as the lineage of cells to be traced back to their origin. In this rapid trek through the life of a muscle, how the production of a mature functional muscle from its early inception is orchestrated will be outlined in exceedingly broad strokes so as to convey the wide range of processes that must be engaged in order to generate a functional muscle. Hopefully, enough information will be provided to encourage those interested to explore further.