It is widely predicted that climate change’s adverse effects will intensify in the future, and along with inadequate agricultural practices, settlement development, and other anthropic activities, could contribute to rapid wetland degradation and thus exert significant negative effects on local communities. This study sought to develop an approach based on the Integrated Water Resource Management (IWRM) in the Ruzizi Plain, eastern Democratic Republic of Congo (DRC), where adverse effects of the climate change are increasingly recurrent. Initially, we analyzed the trends of climate data for the last three decades (1990–2022). Subsequently, the Water Evaluation and Planning (WEAP) approach was employed on two contrasting watersheds to estimate current and future water demands in the region and how local wetlands could serve as reservoirs to meeting water demands. Results indicate that the Ruzizi Plain is facing escalating water challenges owing to climate change, rapid population growth, and evolving land-use patterns. These factors are expected to affect water quality and quantity, and thus, increase pressure on wetland ecosystems. The analysis of past data shows recurrence of dry years (SPI ≤ − 1.5), reduced daily low-intensity rainfall (Pmm < 10 mm), and a significant increase in extreme rainfall events (Pmm ≥ 25 mm). The WEAP outcomes revealed significant variations in future water availability, demand, and potential stressors across watersheds. Cropland and livestock are the main water consumers in rural wetlands, while households, cropland (at a lesser extent), and other urban uses exert significant water demands on wetlands located in urban environments. Of three test scenarios, the one presenting wetlands as water reservoirs seemed promising than those considered optimal (based on policies regulating water use) and rational (stationary inputs but with a decrease in daily allocation). These findings highlight the impact of climate change in the Ruzizi plain, emphasizing the urgency of implementing adaptive measures. This study advocates for the necessity of the IWRM approach to enhance water resilience, fostering sustainable development and wetland preservation under changing climate.
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