This study introduces an empirical model designed to predict the maximum values of time-dependent data across four turbulence-related fields: hydrogen combustion in renewable energy systems, urban microclimate effects on cultural heritage, shipping emissions, and road vehicle emissions. The model, which is based on the mean, standard deviation, and integral time scale, employs two parameters: a fixed exponent ‘ν’ (0.3) reflecting time scale sensitivity, and a variable parameter ‘b’ that accounts for application-specific uncertainties. Integrated into the Computational Fluid Dynamics (CFD) framework, specifically the Reynolds-Averaged Navier–Stokes (RANS) methodology, the model addresses the RANS approach’s limitation in predicting extreme values due to its inherent averaging process. By incorporating the empirical model, this study enhances RANS simulations’ ability to predict critical values, such as peak hydrogen concentrations and maximum urban wind speeds, which is essential for safety and reliability assessments. Validation against experimental and numerical data across the four fields demonstrates strong agreement, highlighting the model’s potential to improve CFD-RANS predictions of extreme events. This advancement offers significant implications for future CFD-RANS applications, particularly in scenarios demanding fast and reliable maximum value predictions.