To address the problem that the hydraulic turbine governing system (HTGS) exhibits poor anti-disturbance ability and instability phenomena under traditional PID control, an improved new integral sliding mode control strategy based on a nonlinear disturbance observer (NISMC-NDO) is designed for the HTGS. This study first establishes a nonlinear mathematical model of HTGS and analyzes its dynamic characteristics. The uncertain disturbances of the system are then accurately estimated using a disturbance observer, and a suitable nonlinear gain function is designed to achieve feedforward compensation of the controller by ensuring that the disturbance observation error converges. To design the controller, a proportional-integral sliding mode surface is selected, and the sliding mode exponential convergence law is improved by using the nonlinear power combination function fal instead of sign or sat. This improves the system’s stability, convergence speed, and tracking accuracy. The simulation results demonstrate that the equilibrium point can be quickly reached and stabilized by the HTGS with chaotic phenomena under the influence of NISMC-NDO. Furthermore, this paper also verifies that the designed controller has good dynamic performance. The findings of this study can serve as a valuable reference for optimizing the operation of hydraulic turbine regulation systems in control applications.