There is global interest in decreasing methane (CH4) emissions from ruminants due to their negative impacts on the efficiency of the livestock industry and the environment. The present study was conducted to evaluate the effects of a natural combination of garlic and citrus, Mootral, as a novel feed supplement on behavior, feed intake (FI), rumen fermentation, digestibility, growth performance, and CH4 reduction in sheep. Four Corriedale wether sheep, kept in individual metabolic cages and used in a 4 × 4 Latin square design, were fed a 50 : 50 grass hay : concentrate ratio diet at 55 g dry matter/kg BW0.75/day. Mootral was supplemented at four concentrations: 0 (control), 1, 5, and 10 g/kg on a dry matter (DM) basis. The experiment was performed over four 21-day periods, each consisting of 14 days for the adaptation period and 7 days for sample collection. Health status was checked daily, while body weight was recorded weekly. Refusal feed, fecal, and urine samples were collected for 5 days. Behavioral observations were performed for 2 continuous days. CH4 and carbon dioxide (CO2) emissions were quantified by an open-circuit respiratory system on days 19 and 20, while rumen fluid was collected three times, both before (0 h) and after (3 and 6 h) morning feeding on day 21. The results of the current study showed that animals supplemented with Mootral dedicated more time to eating (P < 0.05) and had a higher frequency of lying around feeding time (P < 0.001) than non-supplemented animals. Continuous observation revealed that Mootral supplementation decreased the incidence of oral non-nutritive behaviors (P < 0.001) and abnormal behavior (P = 0.016) of the sheep around feeding times compared with the control group. Moreover, rumination activity was observed to be higher for supplemented animals through instantaneous scan sampling data (P < 0.001). Mootral supplementation did not affect total FI or any rumen fermentation parameters, digestibility, or growth performance. Compared with the control group, 5 and 10 g Mootral/kg DM decreased the CH4 emission yield per digestible DM intake up to 7 % (P < 0.05) and 12.8 % (P < 0.01), respectively, while no effect on CO2 emissions was observed. In conclusion, Mootral, a combination of garlic and citrus, is a promising natural feed supplement that can be used to reduce CH4 emissions from ruminants without causing any negative impact on FI, rumen fermentation, or digestibility, thereby leading to improved animal welfare.