Transcatheter aortic valve replacement (TAVR) and transcatheter mitral valve replacement (TMVR) are catheter-based interventional techniques for treating patients having high risk for surgical aortic or mitral valve replacement, respectively. While TAVR is a technique for treating severe aortic stenosis, TMVR is primarily used for treating mitral regurgitation. Echocardiography is the initial imaging modality used for a detailed assessment of the mitral and aortic valve lesions. Multidetector computed tomography (MDCT) is then used as a complementary tool to provide additional information essential for pre-procedure planning. High spatial resolution and good temporal resolution of MDCT along with multiplanar reconstruction technique permit a comprehensive assessment relevant for the multiple aspects of preprocedural planning. The current article outlines the MDCT acquisition protocols, reconstruction techniques, and assessment of various essential parameters for TAVR and TMVR.