Inhibition Of Return Research Articles

Does Self-Associating a Geometric Shape Immediately Cause Attentional Prioritization?

In many cognitive tasks, stimuli associated with one's self elicit faster responses than stimuli associated with others. This is true for familiar self-representations (e.g., one's own name), for new self-associated stimuli, and for combinations of both. The current research disentangles the potential of self- versus stranger-representations for familiar, new, and paired (familiar + new) stimuli to guide attention. In Study 1 (N = 34), responses to familiar and new self- versus other representations were tested in a dot-probe task with a short stimulus-onset asynchrony (SOA; 100 ms). Study 2 (N = 31) and Study 3 (N = 35) use a long SOA (1,000 ms) to test whether the findings are mirrored in inhibition of return (IOR). We observe significant performance differences for targets following self- versus stranger-associated stimuli (i.e., a cuing effect or IOR depending on the SOA length), yet only when familiar representations are present. This indicates that, under conditions of attentional competition between self- and stranger-representations, familiar self-representations impact the distribution of attention while new self-representations alone do not.

Exogenous Attention and Inhibition of Return in the Foveola

Exogenous Attention and Inhibition of Return in the Foveola

Human electrophysiology reveals delayed but enhanced selection in inhibition of return

Visual environment tends to be stable over the short run. An immediately visited location often doesn't provide new information and can be safely inhibited, as exemplified by inhibition of return (IOR)—attention takes longer to return to a previously cued location. Attention selection at this inhibited location has been widely characterized as inferior, in which the target at the cued location has diminished salience, with lower rate of accumulation in the priority map for attention selection. We demonstrate here that an electrophysiology index of visual selection—the N2pc component—is delayed but enhanced at the cued than uncued location, and this enhancement in the N2pc amplitude predicts reduction in the behavioral IOR effect. By isolating a pure target N2pc, these results reveal an active attention enhancement mechanism that facilitates adaptive allocation of attention when a target appears at a previously cued location, potentially acting as a compensation mechanism for inhibition.

Contextual Similarity Between Successive Targets Modulates Inhibition of Return in the Target-Target Paradigm

Inhibition of return (IOR) refers to slower responses to a target presented at a previously cued vs. uncued location. The present study investigated the role of memory retrieval in IOR by manipulating the contextual similarity between two successive targets in the target-target IOR paradigm. Successive targets were presented in either the same color (same-context condition) or different colors (different-context condition). Results of two experiments showed that IOR was greater in the same-context than the different-context condition. In addition, Experiment 2 showed that this context effect occurs with long response times (RTs), suggesting that memory retrieval, which requires time to manifest, plays an important role in IOR.

The Influence of Inhibition of Return and Level-Priming on the Global Precedence Effect.

The aim of the reported experiment was to investigate the effects of inhibition of return (IOR) and level-priming on the global precedence effect (GPE). The classical hierarchical stimuli combined with IOR and the level-priming paradigm were used. The participants selectively attended to the global or local features of compound numerals. The results showed that IOR inhibited the response to the global and local features; moreover, the inhibition effect on the perception of the global features was stronger than that of the local features in the stage of inhibitory processing, resulting in the disappearance of GPE. However, level-priming promoted the response to global and local features, and the promotion effect was stronger on local features, leading to the disappearance of GPE as well. These findings suggested that hierarchical processing was affected by IOR and level-priming, which were correlated with selective attention. Thus, it indicated that global precedence could be involved in attentional mechanisms.

Bilingualism modifies disengagement of attention networks across the scalp: A multivariate ERP investigation of the IOR paradigm

A recent approach to explaining the domain-general cognitive outcomes of bilingualism is to consider the role of disengagement of attention, rather than the engagement of focused attention or inhibition as typical in most accounts. The present study pursues this approach by examining the neurophysiological changes associated with disengagement of attention in young adults performing an inhibition of return (IOR) paradigm while EEG was recorded. Participants were drawn from a diverse community and varied widely in their bilingual experience. There were three main findings. First, dividing the sample into dichotomous groups based on language proficiency did not lead to reliable group differences on the task. Second, using instead continuous measures of bilingualism across the sample indicated that greater bilingual experience and proficiency were associated with the magnitude of the IOR effect, with more bilingual individuals showing larger and earlier IOR effects. Finally, a network of processes that are temporally and spatially distinct were found to work together to produce facilitation, disengagement of attention, and inhibition of return. These findings contribute to debates regarding the electrophysiological correlates of the IOR effect and provide additional evidence for how bilingualism affects domain-general cognition.

No evidence for an independent retinotopic reference frame for inhibition of return

Inhibition of return (IOR) represents a delay in responding to a previously inspected location and is viewed as a crucial mechanism that sways attention toward novelty in visual search. Although most visual processing occurs in retinotopic, eye-centered, coordinates, IOR must be coded in spatiotopic, environmental, coordinates to successfully serve its role as a foraging facilitator. Early studies supported this suggestion but recent results have shown that both spatiotopic and retinotopic reference frames of IOR may co-exist. The present study tested possible sources for IOR at the retinotopic location including being part of the spatiotopic IOR gradient, part of hemifield inhibition and being an independent source of IOR. We conducted four experiments that alternated the cue-target spatial distance (discrete and contiguous) and the response modality (manual and saccadic). In all experiments, we tested spatiotopic, retinotopic and neutral (neither spatiotopic nor retinotopic) locations. We did find IOR at both the retinotopic and spatiotopic locations but no evidence for an independent source of retinotopic IOR for either of the response modalities. In fact, we observed the spread of IOR across entire validly cued hemifield including at neutral locations. We conclude that these results indicate a strategy to inhibit the whole cued hemifield or suggest a large horizontal gradient around the spatiotopically cued location. Public significance statementWe perceive the visual world around us as stable despite constant shifts of the retinal image due to saccadic eye movements. In this study, we explore whether Inhibition of return (IOR), a mechanism preventing us from returning to previously attended locations, operates in spatiotopic, world-centered or in retinal, eye-centered coordinates. We tested both saccadic and manual IOR at spatiotopic, retinotopic, and control locations. We did not find an independent retinotopic source of IOR for either of the response modalities. The results suggest that IOR spreads over the whole previously attended visual hemifield or there is a large horizontal spatiotopic gradient. The current results are in line with the idea of IOR being a foraging facilitator in visual search and contribute to our understanding of spatiotopically organized aspects of visual and attentional systems.

Behavioral and neuronal study of inhibition of return in barn owls

Inhibition of return (IOR) is the reduction of detection speed and/or detection accuracy of a target in a recently attended location. This phenomenon, which has been discovered and studied thoroughly in humans, is believed to reflect a brain mechanism for controlling the allocation of spatial attention in a manner that enhances efficient search. Findings showing that IOR is robust, apparent at a very early age and seemingly dependent on midbrain activity suggest that IOR is a universal attentional mechanism in vertebrates. However, studies in non-mammalian species are scarce. To explore this hypothesis comparatively, we tested for IOR in barn owls (Tyto alba) using the classical Posner cueing paradigm. Two barn owls were trained to initiate a trial by fixating on the center of a computer screen and then turning their gaze to the location of a target. A short, non-informative cue appeared before the target, either at a location predicting the target (valid) or a location not predicting the target (invalid). In one barn owl, the response times (RT) to the valid targets compared to the invalid targets shifted from facilitation (lower RTs) to inhibition (higher RTs) when increasing the time lag between the cue and the target. The second owl mostly failed to maintain fixation and responded to the cue before the target onset. However, when including in the analysis only the trials in which the owl maintained fixation, an inhibition in the valid trials could be detected. To search for the neural correlates of IOR, we recorded multiunit responses in the optic tectum (OT) of four head-fixed owls passively viewing a cueing paradigm as in the behavioral experiments. At short cue to target lags (<100 ms), neural responses to the target in the receptive field (RF) were usually enhanced if the cue appeared earlier inside the RF (valid) and were suppressed if the cue appeared earlier outside the RF (invalid). This was reversed at longer lags: neural responses were suppressed in the valid conditions and were unaffected in the invalid conditions. The findings support the notion that IOR is a basic mechanism in the evolution of vertebrate behavior and suggest that the effect appears as a result of the interaction between lateral and forward inhibition in the tectal circuitry.

When do response-related episodic retrieval effects co-occur with inhibition of return?

At some point, spatial priming effects more faithfully reflect response selection processes than they do attentional orienting or sensory processes. Findings from the spatial cueing literature suggest that two factors may be critical: (1) the amount of identity processing that is required in order to respond correctly (feature-based response hypothesis), and (2) the amount of spatial processing that is required in order to respond correctly (space-based response hypothesis). To test the first hypothesis, we manipulated whether observers made single keypress detection or two-choice localization responses to serially presented stimuli in peripheral vision and whether stimulus identity information processing was necessary before responding. Responses were always slowest when the target location repeated, consistent with an attentional orienting bias independent of keypress responding (i.e., inhibition of return; IOR). The localization procedure revealed a subtle additional cost for changing the target location and repeating a response, consistent with a response-related episodic retrieval effect predicted by the Theory of Event Coding (TEC). Neither effect was modulated by the need to discriminate features. To test the second hypothesis, we made spatial processing indispensable to response selection by requiring a decision between a detection and localization response, depending on where the target appeared. IOR was eliminated for detection, but not localization, responses, consistent with the TEC. Collectively, the findings suggest that the amount of space-based, but not feature-based, processing that is required to determine a response is responsible for the response retrieval effects that can co-occur with IOR.

Priming of Attentional Selection in Macaque Visual Cortex: Feature-Based Facilitation and Location-Based Inhibition of Return.

Visual search performance varies with stimulus and response history. Priming of pop-out refers to increased accuracy and reduced response time with repeated presentation of particular singleton and distractor features (e.g., a red target among green distractor stimuli), which are abruptly impaired when singleton and distractor features swap (e.g., green target among red distractors). Meanwhile, inhibition of return refers to the slowing of response time when target location repeats. Neurophysiological correlates of both these phenomena have been reported in the frontal eye field (FEF), an area in the frontal lobe contributing to attentional selection and eye movement planning. To understand the mechanistic origin of these adaptive behaviors, we investigated visual cortical area V4, an area providing input to and receiving feedback from FEF, during feature-based priming of pop-out and location-based inhibition of return. Performing a color pop-out task, monkeys exhibited pronounced priming of pop-out and inhibition of return. Neural spiking from V4 revealed earlier target selection associated with priming of pop-out and delayed selection associated with inhibition of return. These results demonstrate substantial involvement of extrastriate visual cortex in behavioral priming and inhibition of return.

The effect of bimodal divided attention on inhibition of return with audiovisual targets

The effect of bimodal divided attention on inhibition of return with audiovisual targets

Predicting Saccadic Eye Movements in Free Viewing of Webpages

Attention modeling for webpages has emerged as a new research direction in computer vision. Despite an amount of research effort, most studies have focused on estimating webpage saliency to reveal the static location of human fixations. Without temporal information, existing models cannot interpret the dynamic properties of the actual attention process in free-viewing webpages. To solve this problem, we propose a webpage-based saccadic model in this study to model dynamic visual search behaviors of humans when they view webpages. In the first stage, we utilize the support vector machine to learn the mapping from multilevel saliency features to an initial probability of being fixated. In the second stage, we combine the mechanisms of spatial bias and inhibition of return with the estimation of the initial probability to iteratively predict a sequence of successive fixations for each webpage image. Experimental results on a benchmark eye-tracking data set for webpages have demonstrated that the proposed model outperforms the state-of-the-art saccadic methods.

Visual Scanpath Prediction Using IOR-ROI Recurrent Mixture Density Network.

A visual scanpath represents the human eye movements when scanning the visual field for acquiring and receiving visual information. Predicting visual scanpaths when a certain stimulus is presented plays an important role in modeling overt human visual attention and search behavior. In this paper, we presented an 'Inhibition of Return - Region of Interest' (IOR-ROI) recurrent mixture density network based framework learning to produce human-like visual scanpaths under task-free viewing conditions. The proposed model simultaneously predicts a sequence of ordered fixation positions and their corresponding fixation durations. Our model integrates bottom-up features and semantic features extracted by convolutional neural networks. Then the integrated feature maps are fed into the IOR-ROI Long Short-Term Memory (LSTM) which is the core component of the proposed model. The IOR-ROI LSTM is a dual LSTM unit, i.e., the IOR-LSTM and the ROI-LSTM, capturing IOR dynamics and gaze shift behavior simultaneously. IOR-LSTM simulates the visual working memory to adaptively maintain and update visual information regarding previously fixated regions. ROI-LSTM is responsible for predicting the next possible ROIs given the spatially inhibited image feature maps on the feature-wise basis. Fixation duration is predicted by a regression neural network given the viewing history and image feature maps corresponding to currently fixated ROI. Considering the eye movement pattern variations among subjects, a mixture density network is adopted to model the next fixation distribution as Gaussian mixtures and the fixation duration is also modeled using Gaussian distribution. Our model is evaluated on the OSIE and MIT low resolution eye-tracking datasets and experimental results indicate that the proposed method can achieve superior performance in predicting visual scanpaths. The code will be publicly available on URL: https://github.com/sunwj/scanpath.

P.443 Does alcohol use provoke relapse in patients with opioid use disorder stabilized on naltrexone?

Attention resources can be allocated in both space and time. Exogenous temporal attention can be driven by rhythmic events in our environment which automatically entrain periods of attention. Temporal expectancies can also be generated by the elapse of time, leading to foreperiod effects (the longer between a cue and imperative target, the faster the response). This study investigates temporal attention in touch and the influence of spatial orienting. In experiment 1, participants used bilateral tactile cues to orient endogenous spatial attention to the left or right hand where a unilateral tactile target was presented. This facilitated response times for attended over unattended targets. In experiment 2, the cue was unilateral and non-predictive of the target location resulting in inhibition of return. Importantly, the cue was rhythmic and targets were presented early, in synchrony or late in relation to the rhythmic cue. A foreperiod effect was observed in experiment 1 that was independent from any spatial attention effects. In experiment 2, in synchrony were slower compared to out of synchrony targets but only for cued and not uncued targets, suggesting the rhythm generates periods of exogenous inhibition. Taken together, temporal and spatial attention interact in touch, but only when both types of attention are exogenous. If the task requires endogenous spatial orienting, space and time are independent.

On the putative role of intervening events in exogenous attention.

In exogenous attention, two main behavioural effects are usually observed across time: facilitation at short cue-target onset asynchronies (CTOAs), and Inhibition of Return (IOR) at longer CTOAs. The presentation of an intervening event (IE)-i.e., a cue presented at fixation between the peripheral cue and target period-favours the appearance of IOR. However, although there is a general consensus on this empirical modulation, there is no agreement about the putative role of IEs and/or the mechanism/s underlying their effect. While some authors consider IEs as a "cue-back", automatically reorienting attention to fixation, thus allowing IOR to occur, others have considered IEs as events modulating cue-target integration processes, consequently affecting exogenous cueing. Even in this later case, it is not clear whether IEs modulate cueing by inducing an attentional set (top-down) modulation or by inducing a trial-by-trial (bottom-up) online modulation. To disentangle this issue, in two experiments, we manipulated the proportion of trials in which the IE was presented, thus being able to measure the effect of the presence/absence and proportion of IEs. We observed a gradual influence of the % of IEs over cueing effects, which becomes less positive or more negative as the % of IEs increases. This pattern of findings fits well with the idea that facilitation and IOR depend on cue-target integration processes, and presents critical implications for the open debate about the mechanism/s underlying exogenous spatial cueing effects.

Time course of the inhibitory tagging effect in ongoing emotional processing. A HD-tDCS study

When a cueing procedure that usually triggers inhibition of return (IOR) effects is combined with tasks that tap semantic processing, or involve response-based conflict, an inhibitory tagging (IT) emerges that disrupts responses to stimuli at inhibited locations. IT seems to involve the executive prefrontal cortex, mainly the left dorsolateral prefrontal cortex (DLPFC), in cognitive conflict tasks. Contrary to other inhibitory effects, IT has been observed with rather short intervals, concretely when the stimulus onset asynchrony (SOA) between the prime presented at the cued location, and the subsequent target is 250 ms. Here we asked whether IT is also applied to ongoing emotional processing, and whether the left DLPFC plays a causal role in IT using HD-tDCS. In two experiments with an emotional conflict task, we observed reduced conflict effects, the signature of IT, when the prime word was presented at the cued location, and once again when the prime-target SOA was just 250 ms. Also, the IT effect was eliminated when cathodal stimulation was applied to the left DLPFC. These findings suggest that the IT effect involves areas of the executive attention network and cooperates with IOR to favor attentional allocation to novel unexplored objects/locations, irrespective of their emotional content.

What Neuroscientific Studies Tell Us about Inhibition of Return.

An inhibitory aftermath of orienting, inhibition of return (IOR), has intrigued scholars since its discovery about 40 years ago. Since then, the phenomenon has been subjected to a wide range of neuroscientific methods and the results of these are reviewed in this paper. These include direct manipulations of brain structures (which occur naturally in brain damage and disease or experimentally as in TMS and lesion studies) and measurements of brain activity (in humans using EEG and fMRI and in animals using single unit recording). A variety of less direct methods (e.g., computational modeling, developmental studies, etc.) have also been used. The findings from this wide range of methods support the critical role of subcortical and cortical oculomotor pathways in the generation and nature of IOR.

From alternation to repetition: Spatial attention biases contribute to sequential effects in a choice reaction-time task

ABSTRACTObservers often take longer to respond to a visual target when it appears at a recently stimulated location than when it appears at a new location in the visual field. This behavioral impairment — known as inhibition of return (IOR) — is mirrored by a reduction of an event-related potential (ERP) component called the N2pc that has been associated with attentional selection. Together, these findings indicate that the mechanism underlying IOR operates to bias covert attention against re-visiting the most recently attended location. The goal of the present study was to determine how this inhibitory attention bias evolves across successive trials of a two-item search task. Initially, targets appearing at previously attended locations were associated with behavioral IOR and a concomitant reduction of the N2pc. After several successive trials, this initial inhibitory bias was superseded by expectancy-based biases associated with “predictable” inter-trial patterns of location repeats or location changes, in some cases leading to faster responses and a larger N2pc when the target location repeated (facilitation of return). These results provide evidence that biases in the covert deployment of attention are updated dynamically according to the recent selection history and contribute to well-known sequential effects in serial choice reaction-time tasks.

Faclilitation of return by gaze cues: compalison with inhibition of return by peripheral cues.

Faclilitation of return by gaze cues: compalison with inhibition of return by peripheral cues.

Does cultural background predict the spatial distribution of attention?

The current study aimed to explore cultural differences in the covert spatial distribution of attention. In particular, we tested whether those born in an East Asian country adopted a different distribution of attention compared to individuals born in a Western country. Previous work suggests that Western individuals tend to distribute attention narrowly and that East Asian individuals distribute attention broadly. However, these studies have used indirect methods to infer spatial attention scale. In particular, they have not measured changes in attention across space, nor have they controlled for differences eye movements patterns, which can differ across cultures. To address this, in the current study, we used an inhibition of return (IOR) paradigm which directly measured changes in attention across space, while controlling for eye movements. The use of the IOR task was a significant advancement, as it allowed for a highly sensitive measure of attention distribution compared to past research. Critically, using this new measure, we failed to observe a cultural difference in the distribution of covert spatial attention. Instead, individuals from East Asian countries and Western countries adopted a similar attention spread. However, we did observe a cultural difference in response speed, whereby Western participants were relatively faster to detect targets in the IOR task. This relationship persisted, even after controlling for individual variation in attention slope, indicating that factors other than attention distribution might account for cultural differences in response speed. Therefore, this study provides robust, converging evidence that group differences in covert spatial attentional distribution do not necessarily drive cultural variation in response speed.