Ingredients Of Traditional Medicine Research Articles

Agastache rugosa Extract and Its Bioactive Compound Tilianin Suppress Adipogenesis and Lipogenesis on 3T3-L1 Cells

Agastache rugosa, or Korean mint, is an herb used as a spice, food additive and traditional medicinal ingredient. It has desirable effects, such as its antibacterial, antifungal and antioxidant properties. A. rugosa contains many phenolic compounds studied for their various health benefits, with the primary components being tilianin. A. rugosa extract (ARE), which was extracted with ethanol and freeze-dried, contained 21.14 ± 0.15 mg/g of tilianin with a total polyphenol content of 38.11 ± 0.88 mg/g. Next, the antiadipogenic effect of A. rugosa and tilianin was clarified using 3T3-L1 cells, which differentiate into adipocytes and develop lipid droplets. 3T3-L1 cells were treated with ARE or tilianin and lipid accumulation (%) was calculated through oil red O staining. Tilianin elicited dose-dependent decrease in lipid accumulation (% of positive control) (30 μM 92.10 ± 1.19%; 50 μM 69.25 ± 1.78%; 70 μM 54.86 ± 1.76%; non-differentiation 18.10 ± 0.32%), assessed by oil-red-O staining, whereas ARE treatments caused consistent diminution in lipid accumulation regardless of dose (100 μM 86.90 ± 4.97%; 200 μM 87.25 ± 4.34%; 400 μM 88.54 ± 2.27%; non-differentiation 17.96 ± 1.30%), indicating that both compounds have anti-obesity effects on adipocytes. Treatment with ARE lowered the mRNA (PPARγ; C/EBPα; FABP4; SREBP1; ACC; FAS) and protein (PPARγ; C/EBPα; SREBP1) levels of adipogenesis and lipogenesis-related factors. Tilianin showed a greater effect on the mRNA levels compared with ARE. Thus, tilianin and ARE may have anti-adipogenic and anti-lipogenic effects on 3T3-L1 cells and be possible candidates of obesity-related supplements.

Phytochemical Screening and Antihypertensive Testing of Traditional Medicinal Ingredients of Indonesia

Traditional medicinal ingredients originating from the Province of East Kalimantan (Indonesia) with the composition of meniran leaves (Phyllanthus niruri L.), cat whiskers leaves (Orthosiphon aristatus), ceplukan leaves (Physalis minima L.), and lempuyang emprit rhizome (Zingiberis amaricana Bl.) are used to help lower blood pressure by the local community. This study aimed to analyze the content of chemical compounds, determine the levels of chemical compounds, and the antihypertensive effect of these traditional medicinal ingredients. This traditional medicinal herb is made into a fine powder and then brewed with boiling water. Phytochemical screening and determination of levels of phytochemical compounds were carried out on these traditional medicinal ingredients. Testing the antihypertensive effect of these traditional medicinal ingredients was carried out on white male rats. The results of the qualitative analysis showed that the chemical compounds contained in the traditional medicinal ingredients were flavonoids, phenols, tannins, and carbohydrates. Quantitative analysis of the traditional medicinal ingredients showed that the content of flavonoid compounds was 0.6375%, phenolic compounds were 3.2412%, and tannin compounds were 0.6593%. Testing the antihypertensive effect of this traditional medicinal herb on rats can reduce systolic, diastolic, and arterial blood pressure. The conclusion is that this traditional medicinal herb contains phytochemical compounds that can help lower blood pressure in rats.

The Utilization of Tokulo (Kleinhovia hospita L.) as Traditional Medicine by Wawonii Community in Lampeapi Village, Wawonii Island, Southeast Sulawesi

Tokulo (Kleinhovia hospita L.) is an herbal plant, it is widely used as a vegetable and alternative drink for tea by Wawonii community. Tokulo has various benefits to support body health. This plant, especially its leaves have active compounds that is used as ingredients in traditional medicine. This study aims to determine the utilization of this plant as traditional medicine by Wawonii community, the origin of cultivation process and its uses as herbal medicine, as well as it can be used as a basis for policy making by local government for increasing local people’s income.

Ethnobotanical Study of Zingiberaceae Rhizomes as Traditional Medicine Ingredients by Medicinal Plant Traders in the Pancur Batu Traditional Market, North Sumatera, Indonesia

Traditional markets are places for buying and selling medicinal plants and are a source of ethnobotany research data. This study aims to determine the uses and characteristics of Zingiberaceae rhizomes have been used as traditional medicine and traded in the traditional market of Pancur Batu, North Sumatra. This research was conducted with an ethnobotany approach through surveys, interviews and observation participatory. The respondents are all medicinal plants traders in the Pancur Batu traditional market. The things that were asked of the traders included local names, special characters, benefits, and how to recognize the rhizome. The medicinal plant traders in the Pancur batu traditional market have been utilized and traded as many as 10 species of Zingiberaceae rhizome, most of them belonging Curcuma and Zingiber genera. The characteristics of rhizomes are recognized by traders through their size, color, and aroma. The cross-section of the rhizomes of each species is different in structure and color which is used as the main marker for each species. Rhizoma Zingiberaceae is used as the main ingredient for tawar (semi-solid medicinal herbs consumed by brewing), parem (solid medicinal ingredients), and oukup (traditional Karo sauna). The rhizome aroma of each species belonging Zingiberaceae is very distinctive which is related to the content of essential oils. The use of Zingiberaceae rhizomes as tawar and parem ingredients needs to be studied further so that they are developed into standardized herbs.

Phytochemical Screening, Antioxidant and Sperm Viability of Nelumbo nucifera Petal Extracts.

Sacred lotus (Nelumbo nucifera Gaertn.; N. nucifera) is a common ingredient in traditional medicine and Thai recipes. Its petal is an agricultural waste from stamen production. There are limitations in the used and pharmacological data of the petals resulting in more petals waste. The aims of this study were to investigate the phytochemical contents, antioxidant activity, and potential effects on sperm viability of aqueous (NAE) and ethanolic extracts (NEE) of both red and white N. nucifera petals. The white NAE had the highest total phenolics content, total tannins content and maximal antioxidant activity. The white NEE had the highest concentration of total flavonoids. Quercetin was a major flavonoid and was found in the aqueous extracts. Both red and white of NAE in the range of 0.22 to 1.76 mg/mL increased sperm viability. The white NAE was prominent in phytochemical content, antioxidant activity, and both red and white NAE effectively increased rat sperm viability in the in vitro model. The white NAE enhanced sperm viability by decreasing oxidative stress. It might be suggested that the N. nucifera petals have benefits for sperm viability health promotion and may increase the economic value of agricultural waste.

Ethnobotany of Medicinal Plants for Internal Diseases in the Village Community of Fatulotu of Lasiolat District of Belu Regency

ABSTRACT: this research aims to study kinds of plants that have medicinal properties, traditional ways to use the plants as traditional medicinal ingredients, and traditional rituals performed in curing internal diseases in the Fatulotu village community of Lasiolat district of Belu regency. This research was carried out between October and November 2013 in the Fatulotu village community of Lasiolat district of Belu regency. The method of this research is field observation. Data were collected by survey and interview tecnique. Survey tecnique is used to obtain data about the kinds of plants that have medicinal properties. While, interview tecnique is used to obtain data about the rituals performed in healing internal diseases. The results showed that there were 22 species of plants that have medicinal properties that could be group into 16 plant families and could cure 16 kinds of internal diseases. The ways of processing plants to be used as traditional medicine ingredients varies depending on the types of diseases. Shaman is accompanied by several villagers performing rituals when taking natural materials. The rituals are carried out in the form of certain treatments on the plants and the recitation of spells by shaman.

The Role of Master Teacher Babussalam (Syekh Hasyim Al-Syarwani) and the Khalifah in Overcoming Public Problems

This study aims to find out The Role of Master Teacher Babussalam (Syekh Hasyim Al-Syarwani) and the Khalifah in Overcoming Public Problems. The type of research used in this research is field study research (qualitative descriptive). Researchers will qualitatively review and describe the results of the reality interviews found in the field, namely by interviewing Tuan Guru / Syekh Babussalam, the caliphs, congregations, and the community around the Sufi institution Tareqat Naqsyabandiyah Babussalam, related to various problems of the ummah and their alleviation. The roles of Tuan Guru Babussalam (Syekh Hasyim Syarwani) and the caliphs are as Islamic counselors, Al- Quran teachers (educators), healers, priests or leaders, caregivers and guides. As an Islamic Counselor, the main task of the master teacher and the caliph is to develop the teachings of the Naqsyabandiyah Order. However, because many people expect assistance and advice on solutions to various life problems. So that master teachers and caliphs help with advice, approaches and wisdom so that people enter the following dimensions. (1) The spiritual dimension, by directing the people to ask forgiveness from Allah SWT, as well as practicing the practices of the Shari'a such as guarding congregational prayers, praying tahajjud to serve parents, giving alms while asking Allah SWT for help. It is different if the problems of life are experienced by the congregation of the Naqsyabandiyah Order, the teacher and the caliphs recommend that they talk and practice the dhikr that is taught. As a healer, it can be seen in the service to the people who come. With the aim of asking for help in healing various diseases, namely to ask for recovery from psychological, medical and non-medical illnesses. With given traditional medicinal ingredients, as well as help with water therapy that has been prayed for by the teacher or the caliph.

Identification and characterization of piperine synthase from black pepper, Piper nigrum L.

Black pepper (Piper nigrum L.) is the world’s most popular spice and is also used as an ingredient in traditional medicine. Its pungent perception is due to the interaction of its major compound, piperine (1-piperoyl-piperidine) with the human TRPV-1 or vanilloid receptor. We now identify the hitherto concealed enzymatic formation of piperine from piperoyl coenzyme A and piperidine based on a differential RNA-Seq approach from developing black pepper fruits. This enzyme is described as piperine synthase (piperoyl-CoA:piperidine piperoyl transferase) and is a member of the BAHD-type of acyltransferases encoded by a gene that is preferentially expressed in immature fruits. A second BAHD-type enzyme, also highly expressed in immature black pepper fruits, has a rather promiscuous substrate specificity, combining diverse CoA-esters with aliphatic and aromatic amines with similar efficiencies, and was termed piperamide synthase. Recombinant piperine and piperamide synthases are members of a small gene family in black pepper. They can be used to facilitate the microbial production of a broad range of medicinally relevant aliphatic and aromatic piperamides based on a wide array of CoA-donors and amine-derived acceptors, offering widespread applications.

Antibacterial activity of Vitex trifolia methanol extract against pathogenic bacteria

Vitex trifolia (Legundi plants) is a plant that is widely used as an ingredient of traditional medicine in Lombok Island for a variety of microbial infections. In this study, a qualitative test of V. trifolia methanol extract was shown to contain secondary metabolites, such as steroids, saponins, alkaloids, flavonoids, terpenoids, and tannins. The inhibitory test of methanol extract of roots, stems and leaves of V. trifolia against pathogenic bacteria (Staphylococcus aureus, Staphylococcus epidermidis, Escherichia coli, and Klebsiella pneumoniae) has been carried out. The experimental design used was a Completely Randomized Design. The treatment factor was the concentration of methanol extract with 4 levels (C1 = 7.5%, C2 = 15%, C3 = 30%, C4 = 60%). The extraction method used was methanol maceration, and the well diffusion method was used in antibacterial activity assay. Data were analyzed by using Anova followed by DMRT test. Anova analysis results showed that differences in the concentration of methanol extract of leaf have a significant effect in inhibiting the growth of all tested bacteria. The DMRT showed that the best treatment was with 60% methanol extract. In this study, S. aureus was the most sensitive bacterium to V. trifolia methanol extract, compared to other test bacteria. It can be concluded that the methanol extract of V. trifolia is an effective antibacterial source, especially against S. aureus.

Animal Forensic Genetics.

Animal forensic genetics, where the focus is on non-human species, is broadly divided in two: domestic species and wildlife. When traces of a domestic species are relevant to a forensic investigation the question of species identification is less important, as the material comes from either a dog or a cat for instance, but more relevant may be the identification of the actual pet. Identification of a specific animal draws on similar methods to those used in human identification by using microsatellite markers. The use of cat short tandem repeats to link a cat hair to a particular cat paved the way for similar identification of dogs. Wildlife forensic science is becoming accepted as a recognised discipline. There is growing acceptance that the illegal trade in wildlife is having devasting effects on the numbers of iconic species. Loci on the mitochondrial genome are used to identify the most likely species present. Sequencing the whole locus may not be needed if specific bases can be targeted. There can be benefits of increased sensitivity using mitochondrial loci for species testing, but occasionally there is an issue if hybrids are present. The use of massively parallel DNA sequencing has a role in the identification of the ingredients of traditional medicines where studies found protected species to be present, and a potential role in future species assignments. Non-human animal forensic testing can play a key role in investigations provided that it is performed to the same standards as all other DNA profiling processes.

Traditional Medicines Prescription and the Potential of Original Indonesian Herbs as Natural Immunomodulators

Traditional medicine is an ingredient or a recipe for components in the form of plant ingredients, animal ingredients, mineral substances, galenic preparations, or mixtures of these ingredients that have been used for treatment from generation to generation and can be applied by the prevailing norms in society. Traditional medicinal herbs can be an option for health maintenance, disease prevention, and health care and strengthening a person's immune system. With low prices and easy-to-find raw materials, traditional medicinal ingredients can be made and consumed at home. This review aims to provide information that native Indonesian herbs act as traditional medicines and also have potential as immunomodulators. The way to get this information is by searching through Google Scholar. The results show that many native Indonesian herbs act as natural immunomodulators. Therefore, it can be concluded that native Indonesian herbs can be developed into phytopharmaca as immunomodulators.

Evaluation of oral toxicity and genotoxicity of Achyranthis Radix extract

Ethnopharmacological relevanceThe root of Achyranthes bidentata Blume, Achyranthis Radix (AR), is used as a traditional medicine ingredient in East Asia. It has anti-inflammatory, anti-oxidative, and anti-diabetic activities. Aim of the studyIn the present study, we aimed to evaluate the oral toxicity and genotoxicity of single-dose and 4-week repeated-doses of AR hot water extract (ARE), under the good laboratory practice principles. Materials and methodsFor oral toxicity studies, SD rats (n = 5 per sex and group) were administered ARE at concentrations of 500, 1000, and 2000 mg/kg/day once (single dose) or once per day for 4 weeks (repeated dose). The non-clinical genotoxicity study consisted of bacterial reverse mutation using Escherichia coli (WP2 uvrA) and Salmonella typhimurium (TA98, TA100, TA1535, and TA1537), in vitro chromosomal aberration test with Chinese hamster lung cells (CHL/IU), and in vivo mouse bone marrow micronucleus test using bone marrow cells collected from male ICR mice (n = 5) that were orally administered ARE. ResultsIn the single-dose oral toxicity study, mortality and treatment-related changes in body weight were not observed throughout the study, and the lethal dose was estimated to be > 2000 mg/kg in rats. In the 4-week repeated-dose oral toxicity study, ARE did not induce significant changes in body weight, organ weight, food intake, or hematological and serum biochemical parameters in any group. In the bacterial reverse mutation test, ARE did not induce gene mutations in any tested strain. In the chromosomal aberration test, ARE did not cause chromosomal aberrations. The micronucleus test showed no significant increase in the number of micronucleated polychromatic erythrocytes or the mean ratio of polychromatic to total erythrocytes. ConclusionsThese results showed that ARE does not induce oral toxicity and genotoxicity in the in vivo and in vitro test systems.

The ethnobotany of Zingibraceae as the traditional medicine ingredients utilized by Colo Muria mountain villagers, Central Java

Zingiberaceae is one of the natural resources used as a natural medicine by Colo Muria mountain villagers in Dawe District, Kudus Regency, Central Java. However, there is no particular study focusing on the use of the Zingiberaceae family in that area. This research aims to identify some species of the Zingiberaceae family utilized as a traditional medicine Colo Muria mountain villagers in Central Java. The data collection method is conducted by a semi-structured interview method, field observation, and documentation. The data was analyzed qualitatively. The result shows that there were 14 species utilized as traditional medicine by the Colo Gunung Muria villagers: Bangle (Zingiber purpureum Roxb), Ginger (Zingiber officinale), Red Ginger (Alpinia purpurata k. Schum.), Cardamom (Elettaria cardamomum (l.) Maton), Kencur (Kaempferia galanga L.), Kunci (Kaempferia pandurata Roxb.), Turmeric (Curcuma domestica Val.), Bitter Ginger (Zingiber zerumbet), Lengkuas (Alpinia galanga (L.) Swartz), Parahulu (Amomum aculeatum Roxb.), Temu Lawak (Curcuma xanthorhiza Roxb.), Temu Giring (Curcuma heyneana Val.), Temu Hitam (Curcuma aeruginosa Roxb.), and Temu Putih (Curcuma zedoaria Berg.). The processing technique of the plants was in two ways: pounded and boiled. While the methods of use were by drinking (61%), rubbed (22%), direct consumption (9%), dripped (4%), and dicethik (squeezed and dripped 4%).

Use of traditional medication on the health of women and children of the Togutil tribe in North Moluccas Province

ObjectivesThe study aims to study 1) how to use traditional medicine in the health of women and children of the Togutil tribe, and describes 2) the local wisdom of forest conservation by the Toguti tribe. MethodsThe research used ethnography study with the design of multiple sites and a tick description approach (thick description and depth). ResultsTogutil women and children always rely on traditional medicine and they do this treatment since ancient times and have always been done from generation to generation. Traditional medicinal ingredients come from the leaves, stems, roots of trees, and fruit of the trees. If the medicine has been given and there is no change, the person who is sick will be taken to a doctor for consultation and recommend other traditional medicine to drink. The role of women and children of the Togutil tribe is more dominant in the home to maintaining the food security and the role of men of the Togutil tribe is outside the home to hunting and farming. ConclusionThe health of Togutil women and children is very important to maintain their survival. The pattern of maintaining their health by consuming traditional medicines.

Potential of Breadfruit Leaf Extract (Artocarpus altilis) As Functional Beverage for Patients with Hepatitis

Breadfruit leaves (Artocarpus altilis) are often used as ingredients of traditional medicine for treatment so it is recommended as a natural alternative medicine for patients with liver disease such as hepatitis. The purpose of this study is the use of breadfruit leaf extract for making syrup as a functional drink for people with hepatitis and see the panelists acceptance of the products made. Tests carried out were tests of the total content of flavonoid compounds and sensory tests on breadfruit leaf syrup. The results showed the highest total content of flavonoid compounds found in the leaves of breadfruit syrup PM (warming) 60 minutes amounted to 290.00 µgQe/mL and PM 90 amounted to 263.33 µgQe/mL while the lowest for the breadfruit leaf syrup PM 30 amounted to 240.00 µgQe/mL. The flavonoid content of all treatments showed a high amount. Based on a sensory test, the panelists preferred the syrup leaves of breadfruit PM 90 with average of 7.01. Therefore, of the three roots, PM 90 was the treatment recommendation. But to know the healing effect more than the consumption of flavonoids in syrup breadfruit leaves against hepatitis patients need to be tested in vivo.

Peningkatan produksi petani Jamur Tiram dengan teknik kultur di Kota Medan

Oyster mushrooms are one of the commodities that people are interested in to meet the needs of healthy and nutritious foods, where the demand of this fungus increases every year. In the city of Medan, oyster mushroom cultivation has begun to develop in the home industry, small to medium scale industries, but in fact it has not yet fulfilled the market demand. The low production of oyster mushrooms caused by the low knowledge of the farmer in preparation of the seed, either F-0, F-1, F-2 or F-3 and ultimately fail in baglog preparation as the final media stage for oyster mushroom production. In the seedlings and backlogs manufacturer should follow the technical culture standard preparation of seedling. Socialization has been carried out by Tim ABDIMAS with the demonstration and introducing culture and sterilization technique using saving energy autoclave, efficient in use for the mushroom farmers and expected after the program the farmers can be confident and become independent in spawn or seedling producing by themselves. The use of autoclave is very effective and significant in reducing the number of contaminated seedlings, as seen in the graph which is also presented in this paper. Knowledge of making mushroom flour with a simple method with low cost in contemporary and hygienic packaging ready to be marketed as a basic ingredient in food processed products or as an ingredient in traditional medicine is also provided.

Pemanfaatan Citrus hystrix DC oleh Pedagang Tumbuhan Obat di Pasar Tradisional Kabanjahe Kabupaten Karo

Citrus hystrix or Jeruk Purut is a type of Rutaceae family that is used as food and traditional medicinal ingredients. Various traditional dishes in Indonesia use Citrus hystrix as a cooking spice and are believed to give a distinctive and refreshing aroma. The use of plants as cooking spices or medicines is related to their bioactive compounds, especially in their use as medicine. The purpose of this study was to explain the relationship between the use of Citrus hystrix and its bioactivity. This study combines market surveys in several traditional markets in North Sumatra and literature studies on the results of research published online and offline about the bioactivity of Citrus hystrix. Respondents in this study were all medicinal plant traders who trade Citrus hystrix. Some of the keywords used for online searches are Citrus hystrix and bioactivity of Citrus hystrix, then they are synthesized so they can explain the purpose. Citrus hystrix has long been traded in the traditional markets of Kabanjahe, Berastagi, and Pancur Batu under the local name "Rimo Mungkur". The local people of North Sumatra, especially the Batak ethnic group, use Citrus hystrix as an ingredient for various ritual events and as a medicinal ingredient. In traditional medicine Citrus hystrix is used to treat fever, fractures, oukup (traditional sauna), malnutrition. Bioactivity of Citrus hystrix is antioxidant, anticancer, antimicrobial, hepatoprotective, and aromatherapy. The bioactivity of Citrus hystrix is thought to be related to its essential oil content, especially limonene, citronellal, and β-pinene. Citrus hystrix is a nautracetical plant that has the potential to be developed as a natural preservative for food and for aromatherapy.

Pemanfaatan Rumput Laut Bagi Masyarakat Kecamatan Pontianak Utara Kota Pontianak

Seaweed is one of the fishery commodities which can be used as a mainstay source of the national fisheries economy. Seaweed has long been known in Indonesia as a food, beverage, vegetable and traditional medicine ingredient. The target area for this community service program (PKM) is North Pontianak District, Pontianak City, which is also one of the tourism destinations for the equatorial monument in Indonesia. The partner group selected in this community service program (PKM) is the people of Batulayang Village, North Pontianak District, who are members of the village PKK group of 20 people divided into 5 small groups. The main objective of this PKM activity is to transfer seaweed utilization science and technology through training and assistance in processing food and beverages made from seaweed. In general, the results of this PKM activity run smoothly and thoroughly. After participating in this PKM activity, the training participants gained new skills about seaweed processing, how to make small-scale business feasibility, and how to market the seaweed products that have been produced. There are ten types of processed seaweed products, namely: seaweed brownies, seaweed pudding, seaweed drinks, seaweed bingke cake, seaweed ointment, seaweed sticks, seaweed crackers, seaweed lunkhead, seaweed jely, and sweets. seaweed. Increasing community skills in the use of seaweed is one of the efforts to support the community's economy and stretch tourism in the North Pontianak District.
 Key words: economy, livelihood, processing, empowerment

Keragaman Familia Tumbuhan Obat Masyarakat Kota Parepare Sulawesi Selatan

Abstract. The research is Diversity of Medicinal Plants Families in the Community of Parepare City, South Sulawesi was conducted in Parepare city on September-October 2020. The ethnobotany research of the Parepare’s people to uncover the local knowledge of the community in utilizing the diversity of plants as medicinal plants. The method used in this research is interview, observation and documentation. Data was collected in four subdistricts in Parepare City, namely Ujung subdistrict, Soreang subdistrict, Bacukiki subdistrict and West Bacukiki subdistrict. The number of informants in this study were 100 people. Ethnobotany data collected in the form of community knowledge about natural resources of plants used as traditional medicinal ingredients. The Parepare’s people use 86 species of plants consisted of 40 families as medicinal materials. Zingiberaceae is the most widely uses species. Parepare’s people used 10 species medicinal plants from Zingiberaceae.Keywords: Diversity, Familia, medicinal plants, inventory, Parepare City, South Sulawesi.

Indigenous knowledge of the people in Karya Usaha Hamlet (Kubu Raya, West Kalimantan, Indonesia) on the processing and diversity of plants that enhance toddler's appetite

Abstract. Panjaitan RGP, Mitalia, Partasasmita R. 2020. Indigenous knowledge of the people in Karya Usaha Hamlet (Kubu Raya, West Kalimantan, Indonesia) on the processing and diversity of plants that enhance toddler's appetite. Biodiversitas 21: 4284-4290. Traditional medicines derived from plants are widely consumed daily by the people of Karya Usaha Hamlet in Indonesia. Not only it is used by adults but also children under the age of five, to increase their appetites. This information was the key to a scientific assessment as it was an effort for health resilience in the community. Therefore, this study aimed to understand the diversity of plant species that is prospective to enhance the toddler's appetite and its process. The method used in this study was a qualitative analysis using a semi-structured interview technique with several informants, which consisted of midwives, health service workers, Posyandu cadres, and people from the ethnic origin. The parts of the plants used as traditional medicinal ingredients were subjected to a qualitative phytochemical screening. The results revealed that seven species were potential as appetite enhancers for toddlers. Furthermore, sixty percent of the informants exhibited Javanese turmeric (Curcuma xanthorrhiza Roxb.) mainly as herbal medicine, while 25.8% and 14.2% chose the fingerroot (Boesenbergia pandurata (Roxb.) Schlecht.) and common turmeric (Curcuma domestica L.), respectively, as main herbal medicine. On the other hand, flavor enhancers on food from the diversity of plants used mostly by midwives in the village were on average of 2.19 species. Medicinal plants were generally processed by boiling and further adding honey or sugar so that children under the age of five will have a sweet flavor as they drink it.