As part of the Fabaceae project of northeastern Mexico and based on field work, collection of botanical samples over the past 37 years, and reviewing botanical materials in national and international herbaria, the diversity of legumes of the subfamilies Caesalpinioideae (excluding tribe Mimoseae), Cercidoideae, and Detarioideae in northeastern Mexico has been recorded. New nomenclatural changes in tribes and genera of the subfamily Caesalpinioideae found in the new scientific bibliography are included. The subfamily Caesalpinioideae (excluding the tribe Mimoseae) includes five tribes: tribe Caesalpinieae, with eight genera (Caesalpinia, Coulteria, Denisophytum, Erythrostemon, Guilandina, Hoffmannseggia, Haematoxylum, and Pomaria) and 21 species; tribe Cassieae with three genera (Cassia, Chamaecrita, and Senna) and 28 species; tribe Ceratonieae with one genus (Ceratonia) and 1 species; tribe Gleditsieae with one genus (Gleditsia) and 1 species. The subfamily Cercidoideae includes two genera (Bauhinia and Cercis) and eight species, and the subfamily Detarioideae includes only one genus and one species (Tamarindus indicus). The total flora of these three subfamilies comprises 18 genera and 63 species, including 56 native species and 7 exotic ones: Bauhinia variegata, Cassia fistula, Ceratonia siliqua, Delonix regia, Erythrostemon gilliesii, Senna alata, and Tamarindus indicus. Endemism includes a total of 22 species and nine infraspecific categories.