Informatics Support Research Articles

Informatics support of thin film deposition with specified structure development

Virtual experiment method which consists of acquisition, systematization, and analysis of large experimental results of thin film deposition technology is described. The data base examples and thin film deposition of any materials result analysis are adduced. Dependence of thin films structure from thin film deposition rate and method and substrate temperature is shown. DLC thin films with amorphous and crystalline structures deposition regimes are represented. WSi thin films for using as thin film resistor in microcircuit and as a superconductor coating in one photon detectors are described. It is shown that the elaborated method of informatics support of research and development in the field of thin film deposition technology dives opportunity to analysis and choose of thin film deposition method and regimes for manufacturing of thin films with specified structure and characteristics.

International Conference on Mechanical, Electronics, Computer, and Industrial Technology

PrefaceInternational Conference on Mechanical, Electronics, Computers, and Industrial Technology (MECnIT 2017) was held in Medan, Indonesia. MECnIT 2017 was hosted by Faculty of Technology and Computer Sciences, Universitas Prima Indonesia. This conference is co-organized by TIMERS (Technology, Informatics, Management, and Engineering Research Support), Universiti Utara Malaysia, National Taiwan University of Science and Technology, Universitas Sumatera Utara, Institut Teknologi Bandung, Universitas Padjajaran, and Asosiasi Perguruan Tinggi Informatika dan Ilmu Komputer (APTIKOM).The MECnIT 2017 have attracted many academicians, scientists, engineers, postgraduates, and other professionals from many countries. These conferences aim to promote interaction among engineers, researchers, and scientists active in the related areas. The events are intended to provide a high-level international forum to present, to exchange, and to discuss recent advances, new techniques, and applications in the field of knowledge discussed in this conference.List of committees and Conferences Photographs are available in this pdf.

Italian Registry of Therapeutic Apheresis

Since the 80s the Italian Society of Apheresis and Cell Manipulation (SIdEM) started to monitor the adverse events of therapeutic apheresis (TA) procedures. In subsequent years other variables were added and a national TA registry was created, with a fluctuating adhesion over the years. From 2010 to 2013 the Registry was shared with the Italian Society of Nephrology (SIN): the collection method required data of each patient and a lack of adhesion was observed, mainly because of a heavy workload needed to fill out all the fields. SIdEM was then forced to simplify the form by collecting aggregated data. At the same time, the Italian Privacy Authority (IPA) gave a negative opinion on the use of the SIdEM-SIN registry because it did not prevent the possibility to identify the patients and raised the question whether a national registry could be managed by a scientific society or if it should be under the control of the Regulatory Authority (CNS - National Blood Centre). Since 2015 SIdEM has continued to collect aggregated data, with a simple form sent to each Italian TA unit. Today the main limitation of our Registry is the absence of informatic and financial support and the main limit of all TA Registries is represented by the voluntary adhesion, which can be limited by lack of time and interest or reluctance to show and share own data. In the last year SIdEM has started to work with the CNS in order to implement and integrate the Registry into the Information System of the Transfusion Units (SISTRA), a system that monitors the activities of the whole Italian blood system.The hypothesis of a Global Registry is fascinating. In order to have the greatest adhesion it should be easy and fast to fill in and, possibly, based on aggregated data.

Penentuan Topik Judul Tugas Akhir Mahasiswa Menggunakan Fuzzy Inference System Tsukamoto

At the end of the study, every student at all levels of public and private universities is required to complete the final project as a condition of graduated students. In the process of final work is not uncommon students experience many difficulties to determine the topic and research title. Therefore it takes a method that can be used to assist students in choosing the topic of the final project in accordance with the value of the courses obtained. Fuzzy Inference System (FIS) Tsukamoto is one method that can be used for decision making with many attributes or criteria. Therefore, in this study used FIS Tsukamoto to determine the topic of the final assignment of students. The attributes used as input criterion are the preliminary final course subject value of Decision Support System (SPK), Artificial Intelligence (AI), Image Processing and Pattern (PCP), Computer Network 1, Computer Network 2, Network Security, Data Mining and Expert System. There are 4 output topics titles final titles used are Intelligent System, Computer Networking, Bio Informatic and Decision Support System (SPK). By using the value data will be modeled method to determine the topic of the final project in accordance with the value obtained. Testing is done by comparing the ranking of predictions with the actual data rank on 100 student value data using Spearman rank correlation test. Spearman rank correlation value of test result that is equal to 0,998. If viewed from the Spearman rank correlation table the results are categorized very well.

Applying GARTNER QUADRANT FOR selecting MULTIFUNCTIONAL AUTOMATION SYSTEM for CERTIFICATION BODY Activities

Currently, informatization support of technological processes and production is a tool that allows improving the set of metrics and performance indicators for the implementation of all groups of business processes. The choice of the approach for the assessment of the advantages of the software spectrum offered on the market plays an important role in the decision-making concerning implementation of the necessary software product. Investments in project solutions for enterprise business processes automation will have a low return in case of selecting commercially inefffective automated platform. Positive economic effects can also be destroyed due to high resource consumption and a long-term payback period. Therefore, in order to make a decision concerning integration system, it is important to select the correct assessment methodology, which would take into account all the main aspects of the reengineering object domain. This work is devoted to the approach to analyzing the segment of systems that have a multifunctional nature, in particular, which make it possible to simultaneously automate the service of providing the flows of documents and customer relationship management (CRM), which, as a rule, are interrelated and complementary. There is a need for such software products for business entities operating in the services sector, including those engaged in commercial certification activities. The difficulty in analyzing this segment of activities is caused by the fact that the Russian market of information and communication technologies offers the systems of modular configuration that are delivered separately, without full functional capabilities. Nevertheless, the proposed technique gives the possibility to make a correct decision on the existence of the class of systems corresponding to certain requirements or, in case of its absence, to consider the option of developing software from scratch.

Design and Application Research of an Power Grid Safety Supervision and Management Business Integrated Platform Based On SoTower3.0

Power grid is a kind of important public infrastructure which plays an essential role in guaranteeing the normal operation of economy and society. With several decades of technological development application, State Grid Corporation of China (SGCC) has made remarkable achievements such as the Ultrahigh voltage(UHV) AC and DC hybrid power system, the widespread use of new technology and equipments and the continuing large quantities of projects construction. New problems occur due to the abovementioned new situation, especially in the power grid information technology aspect. The integrated platform for safety supervision and management of power grid enterprises can improve the informatization level of the power grid safety supervision and management and provide a solid guarantee for the reliable operation of the power grid. This paper introduces SoTower3.0 power grid safety supervision and management integrated platform software, which has8 types of functions, including safety accident analysis, potential safety hazard management, comprehensive business management, safety supervision management, safety evaluation, safety training examination, basic security construction and system management, providing informatization support for the efficiency improvement of the power grid safety supervision and management. In addition, the paper analyzes the advantages of the developed SoTower platform application, introduces the system framework design and the specific contents of the above-mentioned 8 functions. Nowadays, the platform has already been applied in power grid enterprises in China, so the network structure and the effectiveness of the applied platform have also been given in this paper.

Designing for Lived Informatics in Out-of-Clinic Physical Rehabilitation

In this article we focus on how rehabilitees make use of personal data as part of performing their prescribed physical therapy in out-of-clinic settings (e.g., home). Over the past 5 years we have been extensively involved in the design of pervasive and mobile technologies to support out-of-clinic physical rehabilitation. Two strands guide our work: situated and embodied interaction, and the practice and theory of physical rehabilitation. In particular we draw upon the latter’s practice of integrating therapy with the lived everyday settings and the model of Person–Environment–Occupation. We revisit this work from the emerging perspective of lived informatics to bring forward multiple instances of rehabilitees using personal rehabilitation data to make sense of their physical rehabilitation process. We present these instances under four categories: becoming your own standard of reference; marking your life as a rehabilitee; articulating with therapists, partners, and peers; and incorporating exercising with everyday activities. We put forward the Person–Environment–Occupation model as a generative entry point for designing digital technology in support of lived informatics in out-of-clinic physical rehabilitation. Through this article we invite researchers in the field of lived informatics to engage in the design of digital technologies for out-of-clinic physical rehabilitation.

Informatics Support for Basic Research in Biomedicine.

Informatics methodologies exploit computer-assisted techniques to help biomedical researchers manage large amounts of information. In this paper, we focus on the biomedical research literature (MEDLINE). We first provide an overview of some text mining techniques that offer assistance in research by identifying biomedical entities (e.g., genes, substances, and diseases) and relations between them in text.We then discuss Semantic MEDLINE, an application that integrates PubMed document retrieval, concept and relation identification, and visualization, thus enabling a user to explore concepts and relations from within a set of retrieved citations. Semantic MEDLINE provides a roadmap through content and helps users discern patterns in large numbers of retrieved citations. We illustrate its use with an informatics method we call "discovery browsing," which provides a principled way of navigating through selected aspects of some biomedical research area. The method supports an iterative process that accommodates learning and hypothesis formation in which a user is provided with high level connections before delving into details.As a use case, we examine current developments in basic research on mechanisms of Alzheimer's disease. Out of the nearly 90 000 citations returned by the PubMed query "Alzheimer's disease," discovery browsing led us to 73 citations on sortilin and that disorder. We provide a synopsis of the basic research reported in 15 of these. There is wide-spread consensus among researchers working with a range of animal models and human cells that increased sortilin expression and decreased receptor expression are associated with amyloid beta and/or amyloid precursor protein.

Informatics support for clinical decisions

The utilization of Clinical Decision Support (CDS) systems is increasing with implementation of Electronic Health Record (EHR) systems across the USA. One of the first and most studied CDS applications has been computerized provider order entry (CPOE), particularly CPOE related to medications. Many EHR systems check drug dosage, allergies, and drug-drug interactions as clinicians enter their orders, and issue alerts as needed. However, alert overriding in CPOE systems is common practice. Nanji et al ( see page 487 ) reports that over 50% of alerts are overridden at a particular academic health center and proposes how to decrease unintended CPOE effects on workflows and communications ( see page 481 ). Related to workflows, Coiera ( see page 414 ) offers a model to study workspaces in which critical communications among clinicians occur. Many articles in this issue focus on medication management, including three systematic reviews that address barriers and facilitators …

Implementing lung cancer screening: a checklist

1 ISSN 1758-1966 10.2217/LMT.13.76 © 2014 Future Medicine Ltd Lung Cancer Manage. (2014) 3(1), 1–4 Based on the results of the NLST [1], the US Preventative Services Task Force (USPSTF) has affirmed its recommendation regarding the value of low-dose computed tomography (CT) scans in finding early lung cancer [2]. The next steps entail ensuring provisions for appropriate reimbursement followed by national implementation of this screening service. From a clinical perspective, low-dose CT management is quite different from existing management strategies of clinically detected lung cancer. Therefore the transition to this new management approach may be challenging. Inherent in the emergence of lung cancer screening as a recommended service is that the optimal organizational structure to provide this service is not fully defined. Recent articles have outlined how risk stratification and diagnostic workups as well as surgical interventions can be refined to further improve screening outcomes [1,3,4]. For a new multidisciplinary team beginning to provide lung cancer screening care what is the best strategy for rapidly implementing the delivery of safe, quality screening service? Recently, the ‘checklist’ approach has been advocated as a mechanism that decreases harm and enhances the favorable outcomes of complex pathways of care [101]. In this editorial, we will use a checklist as a metaphor to propose how to facilitate the evolution of high-quality lung cancer screening. So what is the checklist to ensure prudent attention to core issues as institutions consider implementation of a lung cancer screening program (Box 1). A critical initial factor is to coordinate this process with the appropriate institutional administrators. An institutional commitment to finance the necessary infrastructure should include space allocation and the provision of the informatic and ancillary staff support required for a successful inception of a screening program. The USPSTF has finalize their recommendation for lung cancer screening services, but a number of private insurers have not yet added this service to their coverage provisions. Therefore, for the intermediate term, such reimbursement issues need to be addressed proactively, so that appropriate financial provisions can be arranged so that individuals that require further

Effective Integration of Informatics Tools to Enhance the Drug Discovery Process

Effective integration of data and laboratory informatics tools promises the ability for organizations to make better informed decisions about resource allocation during the drug discovery and development process, and for more informed decisions to be made with respect to the market opportunity for compounds. There are technologies on the horizon that could dramatically change how informatics organizations design, develop, deliver, and support applications and data infrastructures to deliver maximum value to drug discovery organizations. There are numerous benefits of integrating laboratory informatics tools like Laboratory Information Management System (LIMS), Chromatographic Data Systems (CDS), Electronic Laboratory Notebooks (ELN), and Analytical Instrumentation and Scientific Data Management Systems (SDMS) for drug discovery processes, but there is no well-established path for effective integration of these tools. We propose in this article four new integration models for effective integration of labor...

Primary Care Reform in Montenegro

Abstract Background: Montenegro is a newly independent state. As with many countries of that region, the country was faced with the need to reform its health care system. The overall aims of the reform were to improve the quality of services. This paper describes the process of implementation of the reform and its first achievements in patient satisfaction and quality of services since it has been introduced. Methods: The ministry of health introduced a series of steps that included changes to legislation, financing and manpower structure. Investments in primary care have been made and informatics support was developed. Educational interventions at the undergraduate and postgraduate levels were also introduced. Results: The initial results show that the changes have improved the quality of care provided: the composition of professionals in primary care has improved; preventive activities have remained high. Primary care is more accessible and organization of services is better, which can be seen in reduced waiting times for consultation in primary care and improved satisfaction with health care. Conclusions: The initial results show some progress since the reform was put into place. New measures aimed at raising the level of health care to reach European Union standards are still to be introduced.

When Less Is More

Clinical Informatics Support CenterDepartment of PediatricsGeorge Washington UniversityChildren’s National Medical CenterWashington, DC Center for Pediatric Informatics & The Children’s IQ NetworkDepartment of PediatricsGeorge Washington UniversityChildren’s National Medical CenterWashington, DC *See also p. 413. Dr. Jacobs is a board member for HIMSS and is employed by Children's National Medical Center; has received grant support from Cerner (Adverse Event Collaborative); and additionally has received support for HIMSS, SCCM-Annual Conferences, and board meetings. Dr. Tyler-Beynum has disclosed that she has no potential conflicts of interest.

Telephone care coordination for smokers in VA mental health clinics: protocol for a hybrid type-2 effectiveness-implementation trial

BackgroundThis paper describes an innovative protocol for a type-II hybrid effectiveness-implementation trial that is evaluating a smoking cessation telephone care coordination program for Veterans Health Administration (VA) mental-health clinic patients. As a hybrid trial, the protocol combines implementation science and clinical trial methods and outcomes that can inform future cessation studies and the implementation of tobacco cessation programs into routine care. The primary objectives of the trial are (1) to evaluate the process of adapting, implementing, and sustaining a smoking cessation telephone care coordination program in VA mental health clinics, (2) to determine the effectiveness of the program in promoting long-term abstinence from smoking among mental health patients, and (3) to compare the effectiveness of telephone counseling delivered by VA staff with that delivered by state quitlines.Methods/designThe care coordination program is being implemented at six VA facilities. VA mental health providers refer patients to the program via an electronic medical record consult. Program staff call referred patients to offer enrollment. All patients who enroll receive a self-help booklet, mailed smoking cessation medications, and proactive multi-call telephone counseling. Participants are randomized to receive this counseling from VA staff or their state’s quitline. Four primary implementation strategies are being used to optimize program implementation and sustainability: blended facilitation, provider training, informatics support, and provider feedback. A three-phase formative evaluation is being conducted to identify barriers to, and facilitators for, program implementation and sustainability. A mixed-methods approach is being used to collect quantitative clinical effectiveness data (e.g., self-reported abstinence at six months) and both quantitative and qualitative implementation data (e.g., provider referral rates, coded interviews with providers). Summative data will be analyzed using the Reach Effectiveness Adoption Implementation Maintenance (RE-AIM) framework.DiscussionThis paper describes the rationale and methods of a trial designed to simultaneously study the clinical effectiveness and implementation of a telephone smoking cessation program for smokers using VA mental health clinics. Such hybrid designs are an important methodological design that can shorten the time between the development of an intervention and its translation into routine clinical care.Trial registrationClinicalTrials.gov NCT00724308

Internet of Things Based Auxiliary Control System for Smart Substation

In order to solve the present situation that auxiliary facilities in substation separate from each other and unable to achieve intelligent interactive features, this paper presents the smart substation auxiliary control system based on the IoT (Internet of Things). The system monitors and controls the production auxiliary system of substation, and in the background using IEC61850 communication protocol to achieve the auxiliary production system internal and mutual coordination linkage and information remote transmission. The system integrates all the substation auxiliary facilities, including video monitoring subsystem, security subsystem, lighting subsystem, power supply subsystem and auxiliary system optimal control subsystem, providing smart substation of informatization, automation and interaction auxiliary support.

A classification of errors in lay comprehension of medical documents

Emphasis on participatory medicine requires that patients and consumers participate in tasks traditionally reserved for healthcare providers. This includes reading and comprehending medical documents, often but not necessarily in the context of interacting with Personal Health Records (PHRs). Research suggests that while giving patients access to medical documents has many benefits (e.g., improved patient–provider communication), lay people often have difficulty understanding medical information. Informatics can address the problem by developing tools that support comprehension; this requires in-depth understanding of the nature and causes of errors that lay people make when comprehending clinical documents. The objective of this study was to develop a classification scheme of comprehension errors, based on lay individuals’ retellings of two documents containing clinical text: a description of a clinical trial and a typical office visit note. While not comprehensive, the scheme can serve as a foundation of further development of a taxonomy of patients’ comprehension errors. Eighty participants, all healthy volunteers, read and retold two medical documents. A data-driven content analysis procedure was used to extract and classify retelling errors. The resulting hierarchical classification scheme contains nine categories and 23 subcategories. The most common error made by the participants involved incorrectly recalling brand names of medications. Other common errors included misunderstanding clinical concepts, misreporting the objective of a clinical research study and physician’s findings during a patient’s visit, and confusing and misspelling clinical terms. A combination of informatics support and health education is likely to improve the accuracy of lay comprehension of medical documents.

Laboratory Informatics Tools Integration Strategies for Drug Discovery: Integration of LIMS, ELN, CDS, and SDMS

There are technologies on the horizon that could dramatically change how informatics organizations design, develop, deliver, and support applications and data infrastructures to deliver maximum value to drug discovery organizations. Effective integration of data and laboratory informatics tools promises the ability of organizations to make better informed decisions about resource allocation during the drug discovery and development process and for more informed decisions to be made with respect to the market opportunity for compounds. We propose in this article a new integration model called ELN-centric laboratory informatics tools integration.

A Decade After the Genome, Bioinformatics Comes of Age

A Decade After the Genome, Bioinformatics Comes of Age

CaTIES: a grid based system for coding and retrieval of surgical pathology reports and tissue specimens in support of translational research

The authors report on the development of the Cancer Tissue Information Extraction System (caTIES)--an application that supports collaborative tissue banking and text mining by leveraging existing natural language processing methods and algorithms, grid communication and security frameworks, and query visualization methods. The system fills an important need for text-derived clinical data in translational research such as tissue-banking and clinical trials. The design of caTIES addresses three critical issues for informatics support of translational research: (1) federation of research data sources derived from clinical systems; (2) expressive graphical interfaces for concept-based text mining; and (3) regulatory and security model for supporting multi-center collaborative research. Implementation of the system at several Cancer Centers across the country is creating a potential network of caTIES repositories that could provide millions of de-identified clinical reports to users. The system provides an end-to-end application of medical natural language processing to support multi-institutional translational research programs.

Galaxy: A Web‐Based Genome Analysis Tool for Experimentalists

High-throughput data production has revolutionized molecular biology. However, massive increases in data generation capacity require analysis approaches that are more sophisticated, and often very computationally intensive. Thus, making sense of high-throughput data requires informatics support. Galaxy (http://galaxyproject.org) is a software system that provides this support through a framework that gives experimentalists simple interfaces to powerful tools, while automatically managing the computational details. Galaxy is distributed both as a publicly available Web service, which provides tools for the analysis of genomic, comparative genomic, and functional genomic data, or a downloadable package that can be deployed in individual laboratories. Either way, it allows experimentalists without informatics or programming expertise to perform complex large-scale analysis with just a Web browser.