Artificial intelligence is characterized as non-living intelligence, although attempts are being made to pass from the principles of biological neural networks to artificial living neural networks. The human brain is assumed to be a complex system of physicochemical neurophysiological biochemical integration of neural networks, which encodes a specific type of biological information, cognitive information. Intelligence is a specific quality of the process of thinking as an expression based on the neurophysiological mechanism of prediction. Nowadays, people more and more often speak about the anthropological, axiological crisis, modification and transformation of human nature, the creation of biological hybrids that compete with natural ones. It will hardly be possible to formalize the complexities of the human brain and mind into digital code in artificial intelligence.