Pre-tensing the CFRP strip strengthening RC column can improve the strain lag of the confined concrete and avoid unloading of column in advance. The pre-stress of strip has an important influence of strengthen. Stress loss of the strip pre-tensed by using the device proposed were investigated by using an experimental test. Firstly, the reasons for the stress loss of strip were analyzed according to the working principle of the device and the strengthening procedure. Then the primary causes of the stress loss, such as friction, relaxation and removing device, were experimentally tested. The influence of the pretension, detail and sectional geometric dimension on the stress loss of the strip were studied. The results show that all three types of pre-stress losses increase significantly with the initial stress. Increasing the cross-sectional size would reduce the relaxation and unwinding losses, but it has little effect on friction losses. The influence of fillet radius on the pre-stress loss was negligible, but in order to avoid premature tearing of local CFRP caused by stress concentration, the chamfer should be made as large as possible within the thickness of concrete protective cover. The test also found that friction was the main cause of stress loss, and friction loss accounts for more than 90% of the total loss.