Influence Of Different Methods Research Articles

The influence of different methods of hysteroscopic metroplasty using a bipolar resectoscope on the restoration of reproductive function in women with a septate uterus

Uterine septum is the most common congenital anomaly of the uterus, accounting for 35% of all diagnosed malformations. Data on the effectiveness of restoring reproductive function in women with a septate uterus after hysteroscopic metroplasty are contradictory, there are no data on the comparison of reproductive results after removal and dissection of the septum using a bipolar hysteroresectoscope. The purpose of the study was to assess the effectiveness of reproductive function recovery after dissection and removal of the uterine septum using a bipolar hysteroresectoscope. Material and methods. 78 patients of group B with uterine septum, reproductive failure, bipolar hysteroscopic metroplasty were under observation. Among the examined patients, 39 suffered from miscarriage and 39 suffered from infertility. 37 women of the BI group underwent hysteroscopic bipolar dissection of the uterine septum; 41 women of the BII group underwent hysteroscopic bipolar resection of the septum. Results and their discussion. Within 2 years after metroplasty, pregnancy occurred in 86.49% of women in the BI group and in 100% of women in the BII group (p>0.05); the specific weight of miscarriages was 9.38% and 0.00%, respectively (p>0.05); childbirth - 58.88% and 70.97% (p>0.05); premature births – 17.65% and 6.45% (p>0.05); term deliveries - 38.24% and 64.52% (p<0.04, SD 0.34 [0.12-0.93]). In women with initial infertility, pregnancy occurred in 61.54% of women in the BI group (n=13) within 2 years after the operation, in 69.23% in the BII group (n=13) (p>0.05); the specific weight of miscarriages was 25.00% and 22.22%, respectively (p>0.05); childbirth - 75.00% and 77.78% (p>0.05); premature births – 12.50% and 11.00% (p>0.05); term deliveries - 62.50% and 66.67% (p>0.05). Analysis of recovery of reproductive function 2 years after surgery in women with initial miscarriage showed that 90.48% of women in the BI group became pregnant, 94.44% in the BII group (p>0.05); the specific weight of miscarriages was 31.58% and 11.76%, respectively (p>0.05); childbirth - 68.42% and 88.24% (p>0.05); premature births – 26.32% and 5.88% (p>0.05); term deliveries - 42.11% and 82.35% (p<0.02, SD 0.16 [0.03-0.73]). Conclusions. The use of the technique of removal of the uterine septum during bipolar hysteroresectoscopy compared to the technique of its dissection in women with a septate uterus and reproductive failure leads to a probable increase in the termination of pregnancy by term delivery both in the general group and in the group of patients with initial miscarriage.

Meta-heuristic Techniques in Microgrid Management: A Survey

As a small energy system, microgrid plays an important role in utilizing distributed energy resources, improving traditional energy networks, and building intelligent integrated energy systems. However, microgrid management is always a challenging optimization problem due to different factors. Meta-heuristics have been widely used to solve complex optimization problems in many fields, including energy systems. However, there is a lack of a systematic summary of the application of meta-heuristics in microgrid management. This paper aims to review the application of meta-heuristics in microgrid management, summarize the contributions and influences of different methods, and provide further insights and suggestions for future research.

Influence of different methods for calculating gestational age at birth on prematurity and small for gestational age proportions: a systematic review with meta-analysis

BackgroundRecognizing premature newborns and small-for-gestational-age (SGA) is essential for providing care and supporting public policies. This systematic review aims to identify the influence of the last menstrual period (LMP) compared to ultrasonography (USG) before 24 weeks of gestation references on prematurity and SGA proportions at birth.MethodsSystematic review with meta-analysis followed the recommendations of the PRISMA Statement. PubMed, BVS, LILACS, Scopus-Elsevier, Embase-Elsevier, and Web-of-Science were searched (10–30-2022). The research question was: (P) newborns, (E) USG for estimating GA, (C) LMP for estimating GA, and (O) prematurity and SGA rates for both methods. Independent reviewers screened the articles and extracted the absolute number of preterm and SGA infants, reference standards, design, countries, and bias. Prematurity was birth before 37 weeks of gestation, and SGA was the birth weight below the p10 on the growth curve. The quality of the studies was assessed using the New-Castle-Ottawa Scale. The difference between proportions estimated the size effect in a meta-analysis of prevalence.ResultsAmong the 642 articles, 20 were included for data extraction and synthesis. The prematurity proportions ranged from 1.8 to 33.6% by USG and varied from 3.4 to 16.5% by the LMP. The pooled risk difference of prematurity proportions revealed an overestimation of the preterm birth of 2% in favor of LMP, with low certainty: 0.02 (95%CI: 0.01 to 0.03); I2 97%). Subgroup analysis of USG biometry (eight articles) showed homogeneity for a null risk difference between prematurity proportions when crown-rump length was the reference: 0.00 (95%CI: -0.001 to 0.000; I2: 0%); for biparietal diameter, risk difference was 0.00 (95%CI: -0.001 to 0.000; I2: 41%). Only one report showed the SGA proportions of 32% by the USG and 38% by the LMP.ConclusionsLMP-based GA, compared to a USG reference, has little or no effect on prematurity proportions considering the high heterogeneity among studies. Few data (one study) remained unclear the influence of such references on SGA proportions. Results reinforced the importance of qualified GA to mitigate the impact on perinatal statistics.Trial registrationRegistration number PROSPERO: CRD42020184646.

Research on Parameter Regionalization of Distributed Hydrological Model Based on Machine Learning

In the past decade, more than 300 people have died per year on average due to mountain torrents in China. Mountain torrents mostly occur in ungauged small and medium-sized catchments, so it is difficult to maintain high accuracy of flood prediction. In order to solve the problem of the low accuracy of flood simulation in the ungauged areas, this paper studies the influence of different methods on the parameter regionalization of distributed hydrological model parameters in hilly areas of Hunan Province. According to the terrain, landform, soil and land use characteristics of each catchment, we use Shortest Distance, Attribute Similarity, Support Vector Regression, Generative Adversarial Networks, Classification and Regression Tree and Random Forest methods to create parameter regionalization schemes. In total, 426 floods of 25 catchments are selected to calibrate the model parameters, and 136 floods of 8 catchments are used for verification. The results showed that the average values of the Nash–Sutcliffe coefficients of each scheme were 0.58, 0.64, 0.60, 0.66, 0.61 and 0.68, and the worst values were 0.27, 0.31, 0.25, 0.43, 0.35 and 0.59. The random forest model is the most stable solution and significantly outperforms other methods. Using the random forest model to regionalize parameters can improve the accuracy of flood simulation in ungauged areas, which is of great significance for flash flood forecasting and early warning.

Greenhouse gas footprint assessment of wood-based panel production in China

China is one of the largest manufacturers, consumers, and traders of wood-based panels (WBPs) globally. The Chinese manufacturing process for WBPs is significantly different from that used in other countries and the greenhouse gas (GHG) footprint assessment of this process has not yet received attention. And a comprehensive evaluation of the effect of different approaches to estimate the delayed emission of biogenic carbon on the GHG footprints of different WBP types is still missing. This study aims to quantify: i) the GHG footprint of WBPs produced in China, and ii) the influence of different methods to assess the delayed emission of biogenic carbon. Cradle-to-gate life cycle models are developed for plywood (PLY), fiberboard (FB), particleboard (PB) and oriented strand boards (OSB). Based on two common end-of-life (EoL) destinations (i.e., incineration and landfill), three approaches to the estimation of the delayed emissions of biogenic carbon in cradle-to-grave assessments are compared. The cradle-to-gate results show that the GHG footprints of PLY, FB, PB and OSB without considering biogenic carbon storage are 538 kg CO2 e/m³, 406 kg CO2 e/m³, 348 kg CO2 e/m³ and 552 kg CO2 e/m³, respectively. For the four types of WBPs, resources extraction stage provides the largest contribution to the GHG footprints (55%–81%), followed by the production process (18%–31%) and raw material transportation (1%–18%). The methodologies used to assess delayed emissions in cradle-to-grave WBP GHG footprint assessments play an important role, especially for incineration scenarios. Finally, emission reduction measures are proposed based on reducing the consumption of adhesives and of energy use in the production process.

Influence of extraction methods on navel orange peel pectin: structural characteristics, antioxidant activity and cytoprotective capacity

SummaryTo make high‐value utilisation of citrus peel waste, three simple extraction techniques (acidic, alkaline and hydrothermal methods) were used to prepare pectins from navel orange peel. The influence of different methods on the structure and antioxidant capacities of all pectin preparations was investigated and compared. All findings revealed that the yield, degree of esterification, molecular weight, monosaccharide composition and antioxidant activities of all samples were significantly different. Alkali‐extracted pectin exhibited highest yield (22.6%), acid‐extracted pectin belonged to high‐ester pectin and hydrothermal‐extracted pectin had lowest molecular weight (109.2 kDa). Interestingly, due to the superior proportion of side‐chain structure, alkali‐extracted pectin possessed a better ability to scavenge free radicals than other samples. More importantly, alkali‐extracted pectin could protect macrophages from H2O2‐induced oxidative damage by enhancing SOD activity and reducing MDA levels. All results contributed to our knowledge of the association among extraction techniques, structural characteristics and resultant bioactivities for pectic polysaccharides.

Агрофізичні властивості та продуктивність сорго зернового за різних способів обробітку ґрунту та доз азотних добрив

The article presents the results of experimental research on the influence of different methods and depth of main tillage and doses of nitrogen fertilizers on the agrophysical properties of the soil and the productivity of grain sorghum. The purpose of the research is to investigate the peculiarities of the formation of the productivity of grain sorghum under different methods of main processing and doses of nitrogen fertilizers during cultivation. Research methods: field quantitative-weight, visual, and laboratory methods. Mathematical and statistical methods are used to systematize and generalize the obtained results. To determine the effectiveness of the application of the main tillage and doses of nitrogen fertilizers on the productivity of grain sorghum, three variants of the methods and depth of the main tillage and three variants of the doses of nitrogen fertilizers were laid. The results. The best agrophysical properties of the dark-chestnut soil under grain sorghum crops both at the beginning of the growing season and at harvest were observed under shelf tillage. Under the influence of the methods, depth, and systems of the main cultivation and fertilization in the crop rotation, changes in agrophysical properties occurred, which led to the creation of various conditions for the growth and development of the culture and the formation of the crop. The yield of grain sorghum for plowing to a depth of 28-30 cm with the application of nitrogen fertilizers with a dose of N60 amounted to 5.44 t/ha on average over the years of research. 3.89 and 2.54 t/ha of harvest were obtained for chisel tillage at the same depth, and for disc tillage – 2.54 t/ha. Conclusion. In the conditions of the southern Steppe of Ukraine, in order to fully realize the adaptive and genetically determined productivity potential of grain sorghum, the most favorable conditions for the growth, development, and formation of the crop are created with the main shelf cultivation of the soil to a depth of 28-30 cm and the application of nitrogen fertilizers with a dose of N60. Keywords: grain sorghum, method and depth of tillage, nitrogen fertilizers, agrophysical properties, productivity.

Application of sodium selenite in the growing technology of white lupin (Lupinus albus L.)

Lupinus is a very diverse genus with many species. The aim of this study was to determine the influence of different methods of application of sodium selenite on the nutritional value of white lupine variety Degas. The highest effect on the content of crude protein was obtained by spraying vegetating plants before the beginning of the flowering phase. In this variant, a class 1 grain was obtained while meeting other requirements of the feed lupin quality standard. This study reveals that the use of selenium contributed to increasing the collection of crude protein at the harvest of white lupin. It is assumed that selenium stimulated the processes of nitrogen entering plants and its redistribution from vegetative to generative organs, as well as activated the synthesis of proteins and their accumulation in the grain of white lupin. It was found that the content of alkaloids in the resulting crop of white lupin did not exceed acceptable levels, which allows it to be used for feed purposes and the preparation of various types of feed. The use of selenium contributed to the increase in the collection of crude protein content at the harvest of above-ground plant mass as it stimulates nitrogen processes in plants and its redistribution from vegetative organs to generative organs, as well as the synthesis of protein compounds in the lupin grain.

ANALYSIS OF COOLING SYSTEM EFFICIENCY

Introduction: The main task of cooling systems in the machine room of a data center is to maintain optimal air parameters at the inlet to IT equipment in accordance with the applicable regulatory documents. If the value of air temperature at the inlet to IT equipment exceeds the optimal value, then so-called hot spots occur — the operation of IT equipment in such places can lead to its overheating and failure. The main reason for the occurrence of hot spots is the violation of air circulation between the hot and cold aisles. Purpose of the study: We aimed to analyze the influence of different methods of hot aisle isolation on the efficiency of IT equipment cooling. Methods: We performed modeling of different methods of hot aisle isolation at different capacity values of IT equipment in the STAR-CCM+ program. Result: As a result of studying temperature and air conditions in a data center, we found the most rational way of isolating the hot aisle — top horizontal containments with vertical blind panels in the free rack space.

An improved competitive particle swarm optimization algorithm based on de-heterogeneous information

The problem of influence dissemination under competitive conditions can truly reflect the form of information in social networks, make reasonable decisions, and analyze the impact gain of different types of messages on users, so as to maximize the benefits of users. How to accurately simulate the spread of competitive influence is still a challenging problem. In such conditions to carry out the information dissemination, viral marketing, disease prevention and other works has a more reasonable significance. However, it is NP-hard to find the most influential node set in a competitive environment. Although an approximate optimal solution can be obtained by using a greedy algorithm to simulate influence propagation under competitive conditions, the time efficiency of the process is very low. Therefore, this paper designs a bionic optimized solution to explore the above problems. Firstly, We set optimization measures to balance the convergence and diversity of the optimization algorithm in the target space, and based on this, we propose a local impact ability evaluation metric based on the de-heterogeneous information within the 2-hop neighborhood of the node set to measure the propagation ability of the node set under competitive conditions. Secondly, the proposed evaluation index is applied to the improved particle swarm optimization algorithm to realize the screening of global optimal particles. Finally, we build a game model to simulate the interest-driven information ownership and dissemination of nodes. The effectiveness and efficiency of our method are verified by comparing the propagation range of competitive influence of different methods and the time complexity of each algorithm on real data sets.

Հողի մշակման տարբեր եղանակների և հողաբարելավիչների ազդեցությունը աշնանացան ցորենի ձմեռադիմացկունության և բերքի կառուցվածքային տարրերի վրա

The article presents the results of the studies on the winter resistance, growth, development, and changes in the structural elements of the crop under the influence of different methods of soil cultivation, equivalent amounts of mineral fertilizers, and biohumus and bentonite application dates against their background. The research conducted in the conditions of waterless agriculture in the Fantan community of the Kotayk region revealed that the cultivation of winter wheat in black soils, out of the three tested methods of soil cultivation (no-till, only loosening: 10-12 cm, deep plowing: 22-25 cm), only loosening with soil discing is the most effective, and the best fertilizing technology is the autumn application of bentonite 3 t/ha on the background of mineral fertilizers N60P60K60 or biohumus equivalent to 3.5 t/ha, in which cases the winter resistance of plants increases, an improved environment for the normal growth and development of autumn crops is created and as a result 51.3 - 54.9 c/ha of grain and 98-102 c/ha of straw yield․

Properties of Microorganisms Isolated from Soils under Conventional and Organic Farming

Оbjective. The article presents the results of research aimed at determining the influence of different methods of tillage on the functional diversity of the soil microbiota. Soil samples containing plant residues from agricultural plots under conventional and organic farming in the Kyiv oblast were used for the study. Methods. Analysis of soil microbiota using differential diagnostic nutrient media by serial dilutions of soil suspension was performed. To quantify the phosphate-mobilizing properties of the isolated microorganisms, the concentration of phosphorus in the solution was measured (grown in NBRIP liquid medium) and detected by the Arenius spectrophotometric method on a Ulab 102UV Spectrophotometer. Results. Th e soil of the plots under organic agrotechnology of cultivation was marked by a greater number of microorganisms of all ecological and trophic groups, except oligonitrophilic and phosphate-solubilizing bacteria. The vast majority of phosphate-transforming bacteria were isolated from the soil of agricultural plots under convection farming. The largest number of cellulose-degrading isolates was isolated from the soil under organic farming plots. Five isolates have the widest range of agronomically useful properties, in particular, the ability to mobilize organic and inorganic phosphates and cellulosolytic activity: 6b, 13b, 18b, 19b, and 8m. After incubation of the isolates on an NBRIP medium at 28°C and 200 rpm for 72 hr, special analyzes for dissolved phosphorus content and pH level in the culture fluid were performed. Isolate 8m selected from chornozem (black soil) under convection agriculture and classified by us as Trichoderma sp. exhibited the highest phosphate-mobilizing activity. The vast majority of bacteria capable of phosphate transformation were isolated from the soil of agricultural areas affected by convection agriculture; and isolates capable of dissolving cellulose — from the soil of organic farming. Conclusions. The initial identification of certain isolates allowed us to classify them as Bacillus and Trichoderma. These isolates are important for further research with the prospect of creating a complex biological preparation with fungicidal properties and the ability to mobilize organic and inorganic phosphorus compounds.

Influence of different methods for classification of lymph node metastases on the survival of patients with oral squamous cell carcinoma

BackgroundDespite the advances in the classification of oral squamous cell carcinoma (OSCC) based on its extension by the TNM system, there is still a need for methods to better classify the patients to predict prognosis and indicate adjuvant therapy. ObjectivesTo analyze the influence of the number of positive lymph nodes (PN), lymph node ratio (LNR), and log odds of positive lymph nodes (LODDS) in survival of patients with OSCC. MethodsClinicopathologic data from patients with OSCC who were treated with curative purposes by surgery and neck dissection (ND) with or without subsequent adjuvant therapies from 1991 to 2015 was retrospectively assessed. The impact of the PN, LNR, LODDS, and other variables on overall survival (OS) and disease-free survival (DFS) was analyzed in univariate and multivariate analyses. ResultsOne hundred nineteen patients were included in this study. In the univariate analysis the PN had a significant impact on OS (p = 0.001) and DFS (p = 0.020), and the LNR had a significant impact on the OS (p = 0.042). In the multivariate analysis with other relevant clinicopathologic variables, the PN was the only significantly independent factor influencing in the OS (p = 0.017) but not in DFS (p = 0.096). ConclusionsThe PN is an independent prognostic indicator for OS and DFS in patients with OSCC and has the potential to aggregate the current AJCC classification. The LNR has potential to be an important prognostic indicator, but the methods for this classification require lapidation. The LODDS did not demonstrate prognostic potential.

Ocular surface and the upper eyelid contour after surgical treatment of upper eyelid retraction in thyroid eye disease

BACKGROUND: Most of the thyroid eye disease (TED) patients have dry eye syndrome. Upper eyelid retraction (UER) is the most common TED symptom and one of dry eye causes. There are two groups of UER surgical treatment methods: transconjunctival and transcutaneous, which can influence on upper eyelid contour, tear film and ocular surface.
 AIM: To evaluate the influence of different methods of UER surgery on upper eyelid contour and ocular surface.
 MATERIALS AND METHODS: 12 patients (19 eyes) were included in the study. Visual acuity test, measurements of UER and palpebral fissure height, Shirmer 1 test, LIPCOF-test and tear break-up time test, Meibomian gland dysfunction staging, corneal and conjunctival fluorescein staining and determination of the ocular surface disease index (OSDI) were performed before surgery and 1 week, 1 and 3 months after. Patients were divided into two groups. Patients of group 1 had UER less than 4 mm and they underwent an upper tarsal muscle extirpation. Patients of group 2 had UER 4 mm and more and they underwent a recession of the levator palpebrae superioris muscle apouneurosis.
 RESULTS: In all patients UER and the height of the palpebral fissure decreased 7 days after surgery and increased again after 3 months, and the dynamics of this change was more pronounced in group 2. There was one patient (both sides) with poor upper eyelid contour after surgery in both groups. BCVA and OSDI improved, while other parameters had a large scatter of data.
 CONCLUSIONS: We have found that surgical treatment of UER caused by TED improves the contour of the eyelid, increases visual acuity and leads to a subjective improvement in the condition of the ocular surface.

Effect of assessment methods on the determination of the critical wind speeds of high-speed trains

Abstract Critical wind speed can play an important guiding role in developing an initial train operation schedule and knowledge of it may prevent safety risks for a train. Hence, the efficient and accurate calculation of the critical wind speeds of trains is critical. This study addresses this topic and focuses on the influence of different methods on the calculation of the critical wind speed. The result reveals that the five-mass and three-mass methods can both be used to determine the critical wind speed of a train more quickly with acceptable accuracy, but these two methods overestimate the crosswind safety risk of the train. With the increase of the train's operating speed, the nonlinearity of the vehicle system is further enhanced. In particular, the influence of the rolling motion between the car body and the bogie is more prominent, and the results of the five-mass method and the multi-body simulation method tend to be the closest. Last but not least, the damping parameters and inertial forces ignored by the quasi-static method will effectively reduce the wind forces transmitted to the track, resulting in a smaller overturning coefficient and higher critical wind speed.

Analysis and visualization methods for detecting functional activation using laser speckle contrast imaging.

Previous studies have used regional cerebral blood flow (CBF) hemodynamic response to measure brain activities. In this work, we use a laser speckle contrast imaging (LSCI) apparatus to sample the CBF activation in somatosensory cortex (S1BF) with repetitive whisker stimulation. Traditionally, the CBF activations were processed by depicting the change percentage above baseline; however, it is not clear how different methods influence the detection of activations. Thus, in this work we investigate the influence of different methods to detect activations in LSCI. First, principal component analysis (PCA) was performed to denoise the CBF signal. As the signal of the first principal component (PC1) showed the highest correlation with the S1BF CBF response curve, PC1 was used in the subsequent analyses. Then, we used fast Fourier transform (FFT) to evaluate the frequency properties of the LSCI images and the activation map was generated based on the amplitude of the central frequency. Furthermore, Pearson's correlation coefficient (C-C) analysis and a general linear model (GLM) were performed to estimate the S1BF activation based on the time series of PC1. We found that GLM performed better in identifying activation than C-C. Additionally, the activation maps generated by FFT were similar to those obtained by GLM. Particularly, the superficial vein and arterial vessels separated the activation region as segmented activated areas, and the regions with unresolved vessels showed a common activation for whisker stimulation. Our research analyzed the extent to which PCA can extract meaningful information from the signal and we compared the performance for detecting brain functional activation between different methods that rely on LSCI. This can be used as a reference for LSCI researchers on choosing the best method to estimate brain activation.

Influence of Rehabilitation Aid with Biofeedback on the Rehabilitation Process during Remote Home-Based Rehabilitation.

Ensuring the regularity and correctness of rehabilitation exercises in the home environment is a prerequisite for successful treatment. This clinical study compares balance therapy in the home environment on a conventional balance mat and an instrumented wobble board, with biofeedback supported by a rehabilitation scheme realized as web-based software that controls the course of rehabilitation remotely. The study included 55 patients with knee injuries. The control group consisted of 25 patients (12 females and 13 males, mean age 39 ± 12 years) and the study group of 30 patients (19 females and 11 males, mean age 40 ± 12 years). Treatment effects were compared using the ICS Balance Platform measurement system. Measurements showed significant differences in the change in ICS Balance platform parameters representing the dynamic stability of the patients. The dynamic stability improved more with the instrumented wobble board. The study did not show an influence of different methods of communication with patients during home-based rehabilitation.

The Relationship Between Composition and Structure: The Influence of Different Methods of Adding CaF2 on the Melt Structure of CaO-SiO2 Slags by Molecular Dynamics Simulations

The Relationship Between Composition and Structure: The Influence of Different Methods of Adding CaF2 on the Melt Structure of CaO-SiO2 Slags by Molecular Dynamics Simulations

Study of endothelin-1 dynamics in the pathogenesis of experimental peritonitis and under the influence of different methods of correction

Background. Currently, one of the most serious complications of acute inflammatory diseases of the abdominal cavity is peritonitis. Objective: to study the development of endothelial dysfunction in experimental peritonitis and compare its correction with a solution of decamethoxine, aminoguadine and L-arginine.
 Materials and methods of research. The study was conducted on 260 white rats of reproductive age (3 months), animal weight — 180–220 g. Animals were divided into 4 groups. Fecal peritonitis was simulated by introducing a 10 % fecal suspension at a dose of 0.5 ml per 100 g of animal weight to the abdominal cavity of laboratory animals by puncture method.
 Research results. Pathological increase in vasoconstriction caused by experimental peritonitis was revealed. It was found that the use of solution, consisting of decamethoxine (10 mg/50 ml of solution) and sodium hyaluronate, is an effective method of rehabilitation and the basis for further correction of complications of experimental fecal peritonitis.The use of aminoguadine in combination with the rehabilitation of the abdominal cavity with a solution of decamethoxine had a positive effect on reducing the level of endothelin-1 in the simulated peritonitis. Combination of nitric oxide donor with decamethoxine solution and sodium hyaluronate nitric oxide donor effect on reducing the level of endothelin-1 in the simulated peritonitis.
 Conclusions: Given the influence of endogenous intoxication on the increase of the marker of vasoconstriction, rehabilitation of the abdominal cavity, the choice of decamethoxine solution (10 mg/50 ml of solution) in the conditions of our study is justified.

Exploring training dental implant placement using static or dynamic devices among dental students.

Static computer-assisted surgery (s-CAIS) and dynamic computer-assisted implant surgery (d-CAIS) are the main digital approaches in guiding dental implant placement. The aim of this study was to explore and compare the learning curves for s-CAIS and d-CAIS by beginners. Three dental students used each dental model for drilling five positions with missing teeth. Operators performed the drilling test for five sets of dental models with an interval of 7 ± 1 days assisted by the d-CAIS system. After a six-month break, the same students performed the drilling test again in the same way but with the s-CAIS system. A total of thirty models were used, and 150 implants were inserted. The operation time and relative deviations were recorded and calculated. Correlations between various deviation parameters and attempts were tested with independent-samples Kruskal-Wallis tests. A significant difference between the two groups was found in the operation time (p < .001). For accuracy, the difference was found in the first attempt of coronal and apical deviations but disappeared as the training went on. As the practice progressed, improvement was evident in the d-CAIS group but not in the s-CAIS group. When reaching the plateau stage of the learning curve of the d-CAIS group (after five attempts), the influence of different methods of guidance was limited between the two groups. A learning curve effect was found in d-CAIS but not in s-CAIS in vitro tests by beginners. The operating procedure of dynamic navigated and static template-guided implant placement was easy to master.