Abstract Extract Reviews of the literature dealing with the interrelationships of nutrition and helminth infestation have been given by Whitlock (1949), Chandler (1953), Hunter (1953), and Frye (1955). Much of the evidence concerning the effects of nutrition on helminth infestation in sheep is the result of field observations. As Stewart and Gordon (1953) have pointed out, especially in the case of infestations with Trichostrongylus colubriformis, the opinion, based on such observations, that nutrition is of prime importance in the resistance of sheep to infestation possibly overlooks other factors concerned. Furthermore, as stressed by Gordon (1960), the distinction between resistance to the establishment of an infestation and resistance to the effects of an infestation is not always clearly stated. However, this differentiation is essential to the understanding of the effect of nutrition on immunity.