In Reply. —We would like to thank Drs Cherry and Falcon for bringing this point to our attention and are grateful for their interest in our article. Looking through the chart, however, we find that idoxuridine was first used on Nov 8, 1963, and then only in the left eye. This therapy was continued through the month. The records show that probing of both inferior canaliculi was unsuccessfully attempted on April 20, 1964. Since the punctal obstruction was bilateral, whereas idoxuridine was used only for the left eye, and since it appeared five months after the use of idoxuridine and not two to three weeks as reported after idoxuridine toxicity, we believe that the punctal stenosis in our patient represents a sequela of acrodermatitis enteropathica and is not due to idoxuridine toxicity.