Infection In Observation Group Research Articles

Effects of behavioral ecology model in healthcare-associated infection management

Objective To explore the effects of behavioral ecology model in healthcare-associated infection management. Methods By random sampling, we selected 800 medical records at Nanyang City Center Hospital of He'nan Province from June 2015 to May 2016 in control group, and 800 medical records from June 2016 to May 2017 in observation group. Control group adopted routine healthcare-associated infection management. On the basis of that in control group, observation group carried out the management with the behavioral ecology model. We compared the nosocomial infection rate, bacterial distribution, knowledge of healthcare-associated infection as well as the qualified rate of hand hygiene between two groups. Results There were 14 cases (1.75%) with healthcare-associated infection in observation group less than that in control group with a statistical difference (χ2=7.913, P=0.006) . Observation group distributed 395 nosocomial infection related pathogens, while control group distributed 475 of that. The scores of knowledge of healthcare-associated infection and hand hygiene in observation group were (96±15) and (98±12) respectively higher than those in control group with statistical differences (P<0.05) . Conclusions The application of behavioral ecology model in strengthening the interaction among consciousness, environment and behavior can improve the cognition on healthcare-associated infection, knowledge and rate of hand hygiene of nurses, reduce the rate of hand hygiene which had positive effects on healthcare-associated infection control. Key words: Nursing staff; Cross infection; Management; Behavioral ecology

Clinical efficacy and safety of linezolid in the treatment of ICU Gram-positive bacterial infections

Objective To observe the clinical efficacy and safety of linezolid in the treatment of ICU patients with Gram-positive bacterial infections. Methods 100 cases of Gram-positive bacterial infections from June 2015 to July 2016 were selected and randomly divided into two groups, including observation group (50 patients) and control group (50 patients) according to random number table.The observation group was treated with linezolid intravenous drip, 0.6g/time, each time interval of 12 hours, treated for 1 week.The control group was given intravenous vancomycin, 1g/time, each time interval of 12 hours medication for a week.The infected sites, pathogens clinical efficacy and the incidence of adverse reactions were analyzed. Results Two kinds of pathogenic bacteria with high infection rate were caused by Staphylococcus aureus infection, and the probability of infection in observation group was 32%, the infection rate was 62%, that in the control group was 24%, and the probability of Staphylococcus aureus infection was 60%.Lung infection and abdominal infection were the most easily infected organs.The lung infection rate of observation group was 46%, abdominal infection rate was 28%, in control group, lung infection rate was 38%, abdominal infection rate was 30%.After treatment, the total effective rate of the observation group was 86%, which was significantly higher than 52% of the control group (χ2=16.00, P=0.001). The incidence rate of adverse reactions of observation group was 4%, which was significantly lower than 22% of the control group (χ2=7.384, P=0.007). Conclusion Linezolid in the treatment of ICU Gram-positive bacterial infections has good effect, and it is worth to be recommended. Key words: Gram positive cocci infection; ICU; Linezolid