Objectives: This study investigates the potential use of the Quintuple Helix Model in strengthening Research, Innovation and Extension (RIE) functions among State Universities and Colleges (SUCs) in the Philippines. It assesses the dynamics between SUCs, the government, industry, and civil society, as well as the natural environment. Method: This study conducts a systematic review of literature and government reports: data from peer-reviewed journals, policy documents, and publications of various key agencies such as the Commission on Higher Education (CHED), Department of Science and Technology (DOST), and National Economic and Development Authority (NEDA) are analyzed. Patterns, gaps and opportunities based on Quintuple Helix were coded using thematic and content analysis. Results and Discussion: SUCs are identified as central to knowledge generation and transformation of society, but their potential is dependent on three interlinked factors; inadequate infrastructures, limited funding and fragmented policies. Theoretical collaborations, from technology transfer processes to community engagement efforts, shed light on the potential of partnerships across different sectors manifested as experimental projects, though persistent challenges present as intellectual property troubles or misaligned interests often hinder successful cooperation. Research Implications: The research highlights the need for coordinated investments in infrastructure, skills and governance reforms. Public-private Partnerships and inter-disciplinary research are then recommended to maximize SUCs contribution to sustainable development. Originality/Value: This study presents a corroborated discourse on the application of the Quintuple Helix Model in the Philippine context of SUCs, its results can yield practical insights, and scalable strategies to enhance the functions of RIE, thus serving as a valuable reference for policymakers, educators, and researchers.
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