The Ganga River, a lifeline for millions of people in the Indian subcontinent, is facing significant environmental challenges due to the construction of barrages and various anthropogenic activities along its course. This review paper examines the effects of barrages and human interventions on the ecological integrity of the Ganga and explores current issues surrounding its deteriorating ecosystem. Furthermore, it discusses the restoration efforts undertaken to mitigate the ecological impacts and restore the river's health. The construction of dams and barrages can aggravate the situation in the context of the Ganga, which is already suffering from the discharge of industrial and agricultural wastes. The construction of various dams, barrages, and hydroelectric projects is affecting the water flow of the Ganga. These affect the water flow, resulting in the accumulation of solid waste on the river bed. Barrages not only affect the water flow but also restrict the migration of aquatic fauna. This affects the hydrological balance of the Ganga as well as the survival and existence of several fish species. This review provides a comprehensive analysis of the effects of barrages and anthropogenic activities on Ganga's ecological integrity, sheds light on the current issues plaguing the river, and highlights the ongoing restoration efforts. By understanding the complex interplay between human activities and ecosystem dynamics, stakeholders can work towards safeguarding Ganga's ecological health and ensuring its sustainable future.