Abstract The full surface digitization of real samples plays a crucial role in fields such as object recognition, industrial quality control, and reverse modeling. To achieve panoramic three-dimensional (3D) reconstruction of samples in complex scenes, we propose an advanced panoramic laser scanning system, consisting of a laser rotation scanning system and a pair of plane mirrors. With the assistance of mirrors, the projected line laser beam can illuminate the sample from full angles in a single scanning sequence, and the camera can capture the 3D information of the sample from several specific viewpoints. The scanning method of rotating allows us to achieve more efficient and larger-scale 3D scanning. After obtaining the sample’s 3D information from different viewpoints using the same calibration parameters, the sample’s full-surface 3D data in the global coordinate can be obtained using mirror reflections. We conducted precision and effectiveness tests on samples with different sizes, materials, shapes, and textures to demonstrate the ability of the proposed method to perform full-surface 3D reconstruction under different scenarios. The experimental results of accuracy evaluation demonstrate that the proposed system can achieve a measurement accuracy at the level of 100 μm. Additionally, the robust experimental results in different scenarios also indicate that the proposed panoramic laser scanning system is capable of accurately obtaining full-surface 3D data of various types of samples, providing a cost-effective, easy-to-use, efficient, high-resolution, and effective approach for achieving panoramic 3D reconstruction.