This article addresses the issue of reduced models to describe turbulent two-phase flows in industrial applications. This work is an application based on Bois (2021) theoretical derivations to connect the spatially-averaged drift-flux model (DFM) to the local Reynolds-averaged two-fluid model (TFM). It presents new opportunities to calibrate closure laws or propose new models based on finer-scale descriptions. Highly convective steady bubbly flows with wall-peaking void fraction profiles are considered. Dispersed bubbles are weakly deformable. A new model dedicated to void fraction dispersion in flat rectangular channels is developed for application into the DFM. The model is calibrated based on reference local Euler-Euler two-fluid simulations of pressurised water and steam mono-dispersed bubbles, in adiabatic conditions. 64 conditions are considered to cover regularly the 3D parameter space in void fraction, Reynolds and Eötvös numbers. The new formulation proposed shows a very good fit with the post-processed predictions of local CFD simulations along with a substantial reduction in grid requirement. The model contains sub-filter correlations between vapour concentration and mixture or relative velocities. This model derived from local simulations is validated a posteriori in an industrial component scale code where the full space-filtered DFM is implemented and resolved. This work proves the benefits and feasibility of one-by-one model development and calibration based on two-fluid simulations.