This research aims to examine and analyze share prices in basic industrial and chemical companies listed on the Indonesian Stock Exchange. The variables tested include Price To Book Value and Return On Equity on Share Prices with Debt To Equity Ratio as an intervening variable. The method used in sampling was purposive sampling. The data used was secondary data obtained from the official IDX website, namely www.idx.co.id and the official website of each company. The research results show that Price To Book Value has an effect on Stock Prices, Return On Equity has no effect on Stock Prices, Debt To Equity Ratio has a positive effect on Stock Prices, Price To Book Value and Return On Equity have no effect on Debt To Equity Ratio. With the Debt To Equity Ratio it is unable to mediate the influence of Price To Book Value and Return On Equity on Share Prices.