Individual Research Research Articles

"I Have Come Because I See You Care About Me": Recruiting Older Black Americans for Genomic Research.

The lack of diversity in genomic studies is a disparity that influences our understanding of human genomic variation and threatens equity in the benefits of precision medicine. Given our current genomic research with Black older adults, we conducted a qualitative study to elucidate participants' knowledge, attitudes, and beliefs about genomic research and research participation and what factors contribute to their willingness to participate and to gain insights into barriers that researchers may have in recruiting Black Americans. We conducted semistructured interviews (N=16) with previous genomic research participants, and an inductive thematic approach was used to code and interpret the data. The mean age was 70, 82% reported <$15,000 annual income, and 100% participated in genomic research. The results note that genomic research is poorly understood despite participation in prior genomic studies, and cultural beliefs about health and managing health impact an individual's research participation. Although not all participants identified with historical distrust, those who did report health system distrust also contributed distrust in research. Relationship building facilitates research participation, especially when perceived as personally relevant and meaningful. Participant incentives and convenience to engage in the study are less important if the personal benefits or relevance of the research are clear. Our results provide new context into the importance of relationship building and research literacy and highlight new considerations for engaging racially diverse populations in research.

Invaluable invisibility: academic housekeeping within the IPCC

This article discusses “academic housekeeping” undertaken within IPCC, understood as the work that is rarely made visible or rewarded, but is nevertheless essential to the success of the organization. It explores the conditions, motivations, and implications for individual researchers involved in the IPCC, with particular emphasis on the invisible, un(der)recognised and unrewarded work they engage in. The empirical material consists of an interview study of researchers involved in the IPCC assessment work. The article concludes with a discussion on the implications of unrewarded work for individual experts, expert organisations, and academic institutions.

Prospects for increasing the functionality of milk-containing products through the use of non-traditional plant raw materials

It is an undeniable fact that nutrition is an important and integral part of human life. Unfortunately, nutrition is not always complete and balanced. It has been established that only rational nutrition is the lever by which it is possible to ensure normal growth and development of the body. Food industry enterprises are trying to create exactly such conditions for adequate human adaptation to the regalia of the surrounding world, namely, they develop and produce specialized products that contribute not only to disease prevention, but also to a stable increase in mental and physical performance. Moreover, these activities do not contradict the state policy in terms of improving the health of the population, through the introduction of healthy nutrition products into the retail network, through various assistance to manufacturing enterprises (subsidies, grant support). Regarding manufacturers of milk-containing food products, the importance of which is undeniable, they quite actively promote product lines for certain segments of the population, for example, children, pregnant and lactating women and the elderly. The main objective of the research is to develop a technology for a milk-containing product (drinking yoghurt) that includes several functions important for humans, namely, functional, diabetic, probiotic ones. The product is given the specified functions by including scientifically substantiated components in the recipe, including those from non-traditional raw materials. Standard and individual research methods have been used to confirm the quality indicators of the finished product. The main results of the research include determining the type of plant material that meets the specified requirements and characteristics and contributes to giving the finished product additional properties (prebiotic, functional, diabetic). The final result of the research is obtaining a product that helps increase the body resistance to the negative environmental effects. The use of secondary plant materials for food purposes, which contributes to the design of a food product with a certain quality composition and specified consumer properties, in comparison with existing analogues, can be considered the novelty of the research.

High levels of Patient Self Advocacy may confound clinical research in understudied patient populations.

To examine the levels of patient self-advocacy in a sample of participants with Chiari Malformation (CM) and to explore how they relate to clinical outcomes. As part of a larger clinical trial addressing chronic pain in patients with CM, 111 participants completed the Patient Self Advocacy Scale (PSAS), the Depression, Anxiety, and Stress Scale (DASS-21), and the Brief Pain Inventory (BPI). PSAS scores indicated a moderately high level of patient self-advocacy (Mean = 3.86 SD = 0.50). The PSAS was not related to depression, anxiety, stress, pain intensity, or pain interference. There were no differences in PSAS according to surgical status (t(61.25) = 0.44, p = 0.66) or use of pain medication (t(109) = 1.05, p = .29). Participants in a clinical trial for CM have high levels of pre-existing patient self-advocacy. Research is needed to understand how patient self-advocacy contributes to the management of CM and how it could impact research of individuals with understudied conditions. NCT05581472.

Accelerating Museum AI Research and Application at the UK Natural History Museum: The NHM AI Lab Programme

The United Kingdom's Natural History Museum (NHM) AI Lab Programme represents a pioneering initiative aimed at harnessing the power of artificial intelligence (AI) to bridge the gap between the museum's extensive collection and cutting-edge AI technologies. Despite its immense potential, the application of AI in museum research remains nascent (e.g., He et al. 2024), with some individual research groups pursuing independent projects without cohesive collaboration with AI experts who know or have experience in similar endeavours. Moreover, differing standards in utilising AI among researchers add complexity to the field. The NHM AI Lab Programme addresses these challenges by co-creating AI pilot projects that bring together the NHM's collection, academic researchers, and AI experts. The NHM AI Lab Programme serves as a nexus for interdisciplinary collaboration, offering expertise in AI, machine learning, data science, and software engineering to support NHM researchers. Through one-to-one consultations and collaborative research projects, the NHM AI Lab Programme facilitates the integration of innovative AI-driven technologies into streamlining digitisation workflows and enhancing Earth and Life Science research at the NHM. In less than a year since its inception, our Programme has achieved several milestones, hosting around 20 diverse projects. These include research projects such as the application of AI for the automatic detection and identification of nannofossils in chalk, the classification of ancient shark and dinosaur teeth, the prediction of mammal disease outbreaks, and the extraction of data from historical bird egg records. Additional projects focus on the automation of mineral analysis and the detection of secondary impact craters on planetary surfaces using AI. Some led to journal publications (e.g., He et al. 2024), while others streamlined NHM researchers' workflows, enhancing their processes of research and digitisation. Moreover, several initiatives have paved the way for new funding streams and collaborative ventures, as well as promising commercial prospects. Certain projects have pioneered the creation or transformation of datasets to meet AI-ready standards, such as data quality, consistency, accessibility, usability, and data governance protocols, helping to embed AI practices into NHM research. This AI Lab Programme can act as a model for other institutions addressing a similar challenge of bridging the gap between AI and their research and collections. This presentation provides insights into the establishment and operation of the NHM AI Lab Programme, shares experiences, highlights successful collaborations, discusses challenges encountered, and outlines future directions.

Conducting fieldwork amidst earthquakes in Nepal: insights from a tourism researcher

This study presents a comprehensive account of the first-hand experiences encountered by a doctoral researcher during fieldwork conducted in Kathmandu, Nepal, in 2015, where two significant earthquakes struck. While existing literature extensively examines the vulnerability of participants, little attention has been given to the challenges faced by researchers themselves within such disaster settings. To address this gap, this study employs an autoethnographic approach to provide a personal and experiential narrative of the researcher’s time in the field. The results of this study shed insight on the difficulties that individual researchers face when working in disaster-affected areas, which is a major contribution to the field of tourism and disaster research. Moreover, it unveils the interplay between individual experiences, logistical intricacies and psychological well-being. This study delves into the practical implications associated with conducting research amidst volatile and uncertain conditions, emphasizing the pivotal role of robust disaster preparedness and response strategies in regions affected by calamities.

The impact of high-intensity interval training on women's health: A bibliometric and visualization analysis.

High-intensity interval training (HIIT) can significantly improve health indicators such as cardiopulmonary function, metabolic efficiency, and muscle strength in a short period. However, due to significant physiological and metabolic differences between males and females, the effects of HIIT vary between genders. Therefore, exploring the specific impacts of HIIT on women's health is crucial. Although there is a considerable amount of individual research on the impact of HIIT on women's health, a systematic bibliometric analysis is still lacking. Publications related to HIIT in women's health were retrieved from the Web of Science Core Collection database, and tools like Microsoft Office Excel 2021, VOSviewer, and Citespace were used to create visualized tables and views. The study included 808 publications distributed across 1234 institutions in 61 countries, authored by 3789 researchers. The United States, Australia, and Canada lead in this domain. Researchers like Astorino TA and Gibala MJ are notably influential in this field. The research has been prominently published in specific academic journals and widely cited by high-impact journals. Highly cited and bursting documents primarily discuss the effects of HIIT on metabolic adaptation, muscle adaptation, cardiovascular health, insulin sensitivity, and exercise performance. Frequent keywords include "aerobic exercise," "sprint interval training," "resistance training," "obesity," "body composition," "aging," and "insulin resistance." Keyword burst analysis reveals that early studies focused primarily on basic concepts and training models, which then expanded to specific physiological responses, applications in particular populations, and impacts on specific diseases. This field has emerged as a research hotspot with international characteristics and extensive academic productivity. Journals and cited journals hold high academic influence, with highly cited and bursty references laying a solid theoretical and practical foundation for the field. In the rapid development of the past decade, research hotspots and frontier directions such as metabolic adaptation, muscle adaptation, cardiovascular health, exercise performance, and personalized training plans have been formed.

Public Perspectives on Consent for and Governance of Biobanking in Japan.

Through strengthened biobank governance, broad consent has been widely accepted as a means to replace donors' discretion based on the information of individual research protocols. Trust and other ethical and social notions, such as reciprocity and solidarity, are key concepts that support biobank governance. The types of allowed broad consent are several; however, they remain unclear, and whether these ethical and social notions are associated with public attitudes toward the consent model is not fully understood. This quantitative study examined two hypotheses: narrower and limited broad consent are more accepted by the public, and acceptance rates for broad consent increase with established measures related to biobank governance. This analysis supported both hypotheses, implying that the limited type of broad consent should be considered an important option, and that a specific type of governance is critical in promoting trust, reciprocity, and solidarity between biobanks and the public.

Utilizing Relative Citation Ratio to Compare Academic Productivity by Gender in Plastic Surgery

IntroductionThe relative citation ratio (RCR) is a bibliometric index utilized to assess research productivity. Mean relative citation ratio (m-RCR) and weighted relative citation ratio (w-RCR) can be utilized to assess individual research quality as well as career-long productivity, respectively. We sought to determine differences in academic productivity between genders and identify demographic variables associated with increased academic productivity. MethodsA list of Plastic and Reconstructive Surgery residency programs was compiled utilizing the American Council of Academic Plastic Surgeons website. Each program department's website was utilized to generate a list of practicing surgeons and respective demographic information. Both mean and weighted RCR were obtained using the iCite, a National Institutes of Health bibliometric tool. Surgeons were excluded if any demographic or RCR data was not accessible. Chi-squared test, Mann–Whitney U test, Kruskal–Wallis test, and multivariable linear regressions were performed. ResultsA total of 785 academic plastic surgeons met the criteria and were included in the analysis, 186 of whom were women and 599 men. Both academic rank and model of residency training were significantly associated with gender in chi-squared analysis (P < 0.05). Mean relative citation ratio was higher among men in departments. Mean w-RCR was higher among men of assistant professor status, chief/chairperson status, integrated model of residency training, faculty size ≥six and in departments and divisions. Academic rank and faculty size were associated with higher w-RCR upon multivariable linear regression. ConclusionsAlthough differences exist in mean w-RCR between men and women in plastic surgery, gender is not a predictor of increased academic productivity. RCR is an accurate means of assessing gender differences in academic productivity as it comprehensively considers both quality and quantity of research and may be superior to other, older bibliometric indices.

Inhaled analgesics for the treatment of prehospital acute pain-A systematic review.

Many prehospital emergency patients receive suboptimal treatment for their moderate to severe pain. Various factors may contribute. We aim to systematically review literature pertaining to prehospital emergency adult patients with acute pain and the pain-reducing effects, adverse events (AEs), and safety issues associated with inhaled analgetic agents compared with other prehospital analgesic agents. As part of an initiative from the Scandinavian Society of Anaesthesia and Intensive Care Medicine, we conducted a systematic review (PROSPERO CRD42018114399), applying the PRISMA guidelines, Grading of Recommendations Assessment, Development, and Evaluation (GRADE), and Cochrane methods, searching the Cochrane Library, Epistemonikos, Centre for Reviews and Dissemination, PubMed, and EMBASE databases (updated March 2024). Inclusion criteria were the use of inhaled analgesic agents in adult patients with acute pain in the prehospital emergency care setting. All steps were performed by minimum of two individual researchers. The primary outcome was pain reduction; secondary outcomes were speed of onset, duration of effect, and relevant AEs. We included seven studies (56,535 patients in total) that compared inhaled agents (methoxyflurane [MF] and nitrous oxide [N2O]) to other drugs or placebo. Study designs were randomized controlled trial (1; n = 60), randomized non-blinded study (1; n = 343), and randomized open-label study (1; n = 270). The remaining were prospective or retrospective observational studies. The evidence according to GRADE was of low or very low quality. No combined meta-analysis was possible. N2O may reduce pain compared to placebo, but not compared to intravenous (IV) paracetamol, and may be less effective compared to morphine and MF. MF may reduce pain compared to paracetamol, ketoprofen, tramadol, and fentanyl. Both agents may be associated with marked but primarily mild AEs. We found low-quality evidence suggesting that both MF and N2O are safe and may have a role in the management of pain in the prehospital setting. There is low-quality evidence to support MF as a short-acting single analgesic or as a bridge to IV access and the administration of other analgesics. There may be occupational health issues regarding the prehospital use of N2O.

Reusable glassware for routine cell culture—a sterile, sustainable and affordable alternative to single-use plastics

Cell culture is a cornerstone of in vitro biological research. Whilst glassware was once commonplace in tissue culture facilities, in recent decades laboratories have moved towards a heavy reliance on single use plastics for routine procedures. Single use plastics allow for accessible, sterile, and often affordable equipment that comes at a high environmental cost. We developed a glassware preparation and cleaning process that allowed the comparison of “traditional” plastic-heavy, and adapted “sustainable,” cell culture practices, to empirically compare the sterility, viability, and proliferative capacity of cells cultured with differing techniques, by observing IL-6 production, morphology, and proliferation rate of cultured human pulmonary fibroblast cells. During which, we calculated the carbon footprint of traditional versus sustainable methods. We additionally endeavored to provide a realistic overview of the steps required to transition to more sustainable cell culture practices and make suggestions to ease the cost, labor, and time required to uptake similar practices in other laboratories. Cells cultured using reusable glassware did not show signs of contamination or stress compared to cells grown solely with plasticware, and glassware baked at 180°C for 120 min was sufficiently decontaminated and depyrogenated for culturing these cells. An individual researcher adopting the same methodology could reduce their carbon footprint by 105.92 kg of Carbon dioxide equivalent (CO2e) whilst also saving money (£408.78) over a 10-year period. We predict that these benefits would be greater if more researchers were to uptake these adapted practices. We intend for this paper to reassure researchers that viable, sterile, and sustainable routine cell culture can be achieved with little upfront cost to the researcher, with the prospective benefit of greatly reducing the cost to the environment. We additionally hope that increased uptake, and thus demand of more sustainable practices, encourages suppliers, policy makers, and funding bodies to make sustainable practices more accessible to individual researchers and institutions worldwide.

A guide to the use of the Inter-University Bio-Backup Project (IBBP) for the sustainability of individual research, even in the event of natural disasters or other unexpected accidents

A guide to the use of the Inter-University Bio-Backup Project (IBBP) for the sustainability of individual research, even in the event of natural disasters or other unexpected accidents

JPaleoDB: One-Stop Search for Japan's Paleontological Collections

The Japan Paleobiology Database (jPaleoDB)*1*2 is a portal website for one-stop searching of paleontological specimens housed in museums across Japan. It contains data for over 430,000 specimen records from 50 museums and institutions as of July 2024 (Table 1). These records include over 7,000 holotypes, more than 100,000 voucher specimens, and represent over 13,000 genera in the Animalia kingdom, over 1,100 genera in the Plantae kingdom, and over 980 genera from other groups. This portal site allows users to search for paleontological specimens from various museums simultaneously, eliminating the need to navigate individual museum databases with different formats and search systems. Search results provide users with detailed information about each specimen, including scientific name, locality, repository, catalog number, type status, and publication. Additionally, results link directly to the corresponding specimen page on each museum's website. jPaleoDB's mission is to establish a network that facilitates the use of paleontological specimens in Japan for research and education. It has further expanded to support curatorial work in each museum by digitizing catalogs to create datasets of currently hidden paleontological collections. jPaleoDB is a research project built and operated by a group of individual researchers from universities and museums, not by a large organization like a national agency or academic society. Integrating data from museums that house specimens is challenging due to the difficulty of automation. As a result, much of the data requires manual curation. In addition, data for voucher specimens described in publications (paleontological papers, illustrated books, catalogs) are incorporated into jPaleoDB by analyzing publicly available resources and examining actual specimens at museums. Because of these reasons, jPaleoDB is still under development. We believe this portal site will be valuable for exploring the comprehensive record of paleontological specimens in Japan and helping users locate specific specimens of interest.

Towards policy impact – an exploration of Clinical Toxicology research cited in policy documents and patents

Introduction Individual researcher impact through scientific citations is carefully monitored, with little attention to the impact of individual journals through policy and patent mentions. We aimed to describe policy and patent mentions for articles published in Clinical Toxicology. Methods Using Altmetric Explorer, we extracted mentions from 1 January 2013 to 31 December 2023, noting the citing source, Clinical Toxicology article title, and author-generated keywords. We used descriptive statistics to analyse the data. Results We identified 165 individual policy documents (n = 139) and patents (n = 26), citing 146 articles with median of 6.4 years between publication and mention. The highest number of citing documents were by the World Health Organization (n = 45), European Monitoring Centre for Drugs and Drug Addiction (n = 22), and United States Centers for Disease Control and Prevention (n = 16). Most patents were registered in the United States (n = 17) and by the European Patent Office (n = 10), with the main classification of human necessities (n = 23). The commonest subjects of papers cited in policy and patents, from keywords, related to medical conditions and symptoms (26%) and recreational drugs (22%). The most cited article was “A systematic review of adverse events arising from the use of synthetic cannabinoids and their associated treatment.” Discussion Clinical Toxicology articles are cited in policy documents and patents, with a comparable number of mentions to the top-ranked journals in the field. This likely contributes to policy impact, but further work is needed to understand how cited articles are used and ripple effects through onwards citations of policy documents. Conclusions Clinical Toxicology is a toxicology journal for which published research gets recognised within influential policy sources. The Journal can play a key role in guiding public health policy through its selection and development of submitted publications.

Commercialisation Tools in Network Research Organisations

The paper aims to identify which commercialisation tools (CT) are employed in network research organisations as exemplified by the Łukasiewicz Research Network, Poland. The authors analyse the state of the art by studying publications in the Web of Science database and present a longitudinal case study. The commercialisation tools identified as a result of the literature review are classified according to an original approach proposed by the authors. Then, the proposed classification is applied to indicate the commercialisation tools used in the Łukasiewicz Research Network, one of the largest recognised research networks in Europe. A longitudinal single case study is used. The data is analysed at two points in time, i.e., for periods before and after the establishment of the Łukasiewicz Research Network. Namely, the tools used by individual research institutes before and after their inclusion in the network as well as the joint use of tools by the institutes making up the network are examined. The presentation is followed by a discussion of the contexts of applying commercialisation tools in the network organisation and individual institutes. Suggested future research includes analyses of the relationship between the use of specific commercialisation tools and commercialisation effectiveness measured by means of a set of commercialisation performance indicators.

Influence of a seed-funded community of practice on the development of academic staff research at a comprehensive University in South Africa

This study seeks to explore the influence of a seed-funded project on the research development, professional growth, and collaboration of academic staff. It employed a qualitative reflective inquiry design to elicit the views of participants in the Domain of Emerging Researcher Excellence (DERE). The DERE has a total of 13 members, but for this study, seven participants were selected as a purposive diverse sample representing various disciplines, career stages, and levels of engagement within the Community of Practice (CoP). The findings revealed two main sources of knowledge platforms that helped participants shape their individual research developments. Participants also highlighted the collaborative activities and knowledge-sharing practices prevalent in the DERE. The interdisciplinary project was considered a gateway for professional growth and career trajectories, facilitating mentorship development activities among academics involved in the project. The study concludes that providing seed funding for CoPs can enhance the growth of academic staff research within universities in emerging economies. This initiative has significant implications for fostering a vibrant research culture within institutions, enhancing research capacity among staff, and promoting collaborative engagement across disciplines. Additionally, institutional policies should outline strategies to ensure the long-term sustainability of CoPs beyond seed funding. The study acknowledges the complexity of promoting research capacity for early-career researchers; however, to ensure sustainability, seed-funded projects that influence individual professional growth and emerging researcher career trajectories should be given opportunities to develop their own funding mechanisms so that they do not become extinct once the seed-funding period elapses.

Checklist and guidance on creating codelists for routinely collected health data research.

Codelists are required to extract meaningful information on characteristics and events from routinely collected health data such as electronic health records. Research using routinely collected health data relies on codelists to define study populations and variables, thus, trustworthy codelists are important. Here, we provide a checklist, in the style of commonly used reporting guidelines, to help researchers adhere to best practice in codelist development and sharing. Based on a literature search and a workshop with researchers experienced in the use of routinely collected health data, we created a set of recommendations that are 1. broadly applicable to different datasets, research questions, and methods of codelist creation; 2. easy to follow, implement and document by an individual researcher, and 3. fit within a step-by-step process. We then formatted these recommendations into a checklist. We have created a 10-step checklist, comprising 28 items, with accompanying guidance on each step. The checklist advises on which metadata to provide, how to define a clinical concept, how to identify and evaluate existing codelists, how to create new codelists, and how to review, check, finalise, and publish a created codelist. Use of the checklist can reassure researchers that best practice was followed during the development of their codelists, increasing trust in research that relies on these codelists and facilitating wider re-use and adaptation by other researchers.

O-GlcNAc informatics: advances and trends.

As a post-translational modification, protein glycosylation is critical in health and disease. O-Linked β-N-acetylglucosamine (O-GlcNAc) modification (O-GlcNAcylation), as an intracellular monosaccharide modification on proteins, was discovered 40 years ago. Thanks to technological advances, the physiological and pathological significance of O-GlcNAcylation has been gradually revealed and widely appreciated, especially in recent years.O-GlcNAc informatics has been quickly evolving. Clearly, O-GlcNAc informatics tools have not only facilitatedO-GlcNAc functional studies, but also provided us a unique perspective on proteinO-GlcNAcylation. In this article, we review O-GlcNAc-focused software tools and servers that have been developed forO-GlcNAc research over the past four decades. Specifically, we will (1) survey bioinformatics tools that have facilitated O-GlcNAc proteomics data analysis, (2) introduce databases/servers forO-GlcNAc proteins/sites that have been experimentally identified by individual research labs, (3) describe software tools that have been developed to predictO-GlcNAc sites, and (4) introduce platforms cataloging proteins that interact with the O-GlcNAc cycling enzymes (i.e., O-GlcNAc transferaseand O-GlcNAcase). We hope these resources will provide useful information to both experienced researchers and new incomers to the O-GlcNAc field. We anticipate that this review provides a framework to stimulate the future development of more sophisticated informatic tools for O-GlcNAc research.

Research participant perceptions of personal utility in disclosure of individual research results from genomic analysis.

This article elaborates research participant perspectives on the communication of individual research results from genomic analyses. While most analyses focus on how to communicate results from the perspectives of clinicians or researchers, there is insufficient data on user perspectives and how this information may be used, valued, and interpreted by patients and their families. The concept of personal utility, which considers factors related to quality of life, including on how information may impact the person's future decisions, has been shown to be particularly relevant to understand research participant perspectives and to move beyond clinical and analytic utility factors such as mortality and morbidity. This article draws from qualitative research of research participants awaiting genomic results in the case of sudden cardiac death. Our results show perspectives of personal utility in communication of genomic results, including cognitive, behavioral, and affective outcomes. Cognitive outcomes include gain of information, improved knowledge of etiology and inheritance characteristics, and curiosity for what might be found. Behavioral outcomes include being able to plan life decisions, while affective outcomes include various coping strategies used. We will also discuss the value of knowing negative results and incidental findings from the research participant's perspective. This contribution gives suggestions on best practices to guide genome analysis returns, including incorporating participant wishes on individualized communication at the consent stage; developing relational autonomy approaches; and engaging them throughout the research trajectory.

Setting up an institutional OMERO environment for bioimage data: Perspectives from both facility staff and users.

Modern bioimaging core facilities at research institutions are essential for managing and maintaining high-end instruments, providing training and support for researchers in experimental design, image acquisition and data analysis. An important task for these facilities is the professional management of complex multidimensional bioimaging data, which are often produced in large quantity and very different file formats. This article details the process that led to successfully implementing the OME Remote Objects system (OMERO) for bioimage-specific research data management (RDM) at the Core Facility Cellular Imaging (CFCI) at the Technische Universität Dresden (TU Dresden). Ensuring compliance with the FAIR (findable, accessible, interoperable, reusable) principles, we outline here the challenges that we faced in adapting data handling and storage to a new RDM system. These challenges included the introduction of a standardised group-specific naming convention, metadata curation with tagging and Key-Value pairs, and integration of existing image processing workflows. By sharing our experiences, this article aims to provide insights and recommendations for both individual researchers and educational institutions intending to implement OMERO as a management system for bioimaging data. We showcase how tailored decisions and structured approaches lead to successful outcomes in RDM practices.