Individual-level Differences Research Articles

Community disadvantage, family socioeconomic status, and racial/ethnic differences in maltreatment reporting risk during infancy

BackgroundChildren are reported for maltreatment during infancy at elevated rates; research has established persistent racial/ethnic differences in the likelihood of reporting to the child protection system (CPS). ObjectiveTo model the influence of race/ethnicity and community disadvantage in CPS reporting during infancy. Participants/settingA population-based dataset consisting of more than 1.2 million children born in California between 2012 and 2014. Vital birth records were probabilistically linked to administrative CPS records. American Community Survey data were used to measure community disadvantage. MethodsFor each child, we coded sociodemographic information from the birth record, assigned the child to a community using their residential address at birth, and captured maltreatment reports from child protection records. We employed a modified Poisson regression model to examine an infant's likelihood of being reported to CPS by race/ethnicity across levels of community disadvantage and after adjusting for individual-level covariates. ResultsInfants born in neighborhoods with the most concentrated disadvantage were reported to CPS at 7 times the rate of children born in the most advantaged neighborhoods (12.3% vs. 1.8%). After adjusting for individual-level covariates, we found that both Black and Hispanic infants born on public insurance were significantly less likely than White infants to be reported for maltreatment overall — and Black and Hispanic infants had a statistically equivalent or lower likelihood of reporting at the two extremes of neighborhood disadvantage. Among privately insured families, Hispanic infants continued to have a lower likelihood of reporting, but Black infants were reported at higher rates than White infants. This Black-White difference persisted in the most advantaged neighborhoods, but disappeared in the most disadvantaged neighborhoods. ConclusionsCapturing individual-level differences in socioeconomic status and associated risk factors is critical to understanding sources of racial/ethnic differences in CPS reporting, including when there is unwarranted variation or disparate treatment. Our findings suggest an elevated likelihood of maltreatment reporting among privately insured Black infants not explained by differences in observed risk or neighborhood, but no such differences were documented for Black or Hispanic infants on public insurance.

Use of Race in Kidney Research and Medicine: Concepts, Principles, and Practice.

Black Americans and other racially and ethnically minoritized individuals are disproportionately burdened by higher morbidity and mortality from kidney disease when compared with their White peers. Yet, kidney researchers and clinicians have struggled to fully explain or rectify causes of these inequalities. Many studies have sought to identify hypothesized genetic and/or ancestral origins of biologic or behavioral deficits as singular explanations for racial and ethnic inequalities in kidney health. However, these approaches reinforce essentialist beliefs that racial groups are inherently biologically and behaviorally different. These approaches also often conflate the complex interactions of individual-level biologic differences with aggregated population-level disparities that are due to structural racism (i.e., sociopolitical policies and practices that created and perpetuate harmful health outcomes through inequities of opportunities and resources). We review foundational misconceptions about race, racism, genetics, and ancestry that shape research and clinical practice with a focus on kidney disease and related health outcomes. We also provide recommendations on how to embed key equity-enhancing concepts, terms, and principles into research, clinical practice, and medical publishing standards.

Effects of 4G-beta-D-Galactosylsucrose in patients with depression: A randomized, double-blinded, placebo-controlled, parallel-group comparative study

Advances in genetic research on microbiome have led to several trials on the effectiveness of synbiotics or probiotics in patients with depression; however, none have evaluated the efficacy of prebiotics. 4G-beta-D-Galactosylsucrose (Lactosucrose, LS) is selectively assimilated by Bifidobacterium as a prebiotic and improves microbiome diversity. However, as it is not clear if LS consumption can improve symptoms of depression, we investigated whether LS intake can improve depressive symptoms, quality of life (QOL), and self-efficacy by conducting a single cite, double-blinded, randomized controlled trial in 20 outpatients with depressive episodes (F32, ICD-10) for 24 weeks. Participants (age range, 36–72 years) were randomized to the LS (n = 9) or placebo groups (n = 11). Primary outcome was improvement in total Montgomery Asberg Depression Rating Scale (MADRS) score, and the secondary outcomes were MADRS subscores, global self-efficacy scale (GSES) score, World Health Organization QOL (WHO/QOL-26) score, and 16S rRNA analysis of the fecal microbiome. LS consumption did not significantly improve total MADRS scores (−2 (−16 to 16) vs 0 (−6 to 10), p = 0.552), but GSES tended to improve in the LS group (2.00 ± 4.24 vs −1.36 ± 4.15, p = 0.091) with a large effect size (Cohen's d = 0.802). Sequencing of 16S rRNA revealed individual-level differences in microbiome diversity changes due to the intervention. Thus, we show that LS intake can improve self-efficacy, but not depressive symptoms, even in a small sample. Additional studies that also regulate diet and ensure adherence may help determine a correlation between depression and the gut microbiome.

Partial migration of Brolgas (Antigone rubicunda) within a restricted range is revealed by GPS tracking

ABSTRACT No quantitative information exists on the movement patterns of Brolga, Antigone rubicunda (Gruidae) although the species is considered to undertake seasonal movements between breeding and non-breeding areas, and has been also described as both non-migratory and partly migratory. Information on this species’ movement behaviour is required to understand its basic ecology and inform conservation management across its range. Thus, we sought to investigate whether Brolgas in southern Australia undertake seasonal movements, to define routes travelled by individuals, and to clarify the species’ migratory status. Here, for the first time for this species, we quantified the distances travelled, timing of movements between breeding and non-breeding areas, and individual-level differences in movement patterns. We deployed GPS transmitters on five adults, six juvenile and 12 unfledged 6–9 week chicks in Victoria, Australia. Individuals were monitored for 71–646 days. These Brolgas showed partial migratory behaviour, with the south-west Victorian population including resident and migrating individuals, moving 6–30 km and 96–111 km between breeding and non-breeding areas respectively and some remaining resident throughout the year. Brolgas moved 1.6 km from roost to foraging areas on average throughout the year, the majority (95%) of these movements were within 5.2 km and overall Brolgas moved shortest distances during the non-breeding season. We discuss the main potential drivers for these movement patterns. These findings may assist local conservation planning and add to our understanding of Australian waterbird movements more broadly.

Association Between Regional Levels of Particulate Matter and Recurrent Falls in Korea.

We investigated the extent of regional disparity of recurrent falls. In addition, we examined the association between particulate matter (PM) and recurrent falls and the association between regional disparity of recurrent falls and regional PM levels. We used data from Korea Community Health Survey 2019 that included 204,395 participants from 237 municipal districts. The independent variables were the annual average PM10 and PM2.5 concentrations measured at the air quality measuring stations in each municipal district. The outcome variable was the experience of falls more than twice in the previous year. Multilevel analyses were conducted to estimate the association between regional PM10 and PM2.5 levels and recurrent falls. The regional variation was greater in the young people than that in the older people. PM10 and PM2.5 levels were positively associated with recurrent falls after adjusting for individual and regional covariates. These associations were more evident in the older group than in the young. PM10 and PM2.5 explained 2.82% and 3.33% of the remaining regional variance in models with individual and regional confounders, respectively. These proportions were greater in the older group (PM10 and PM2.5; 4.73% and 5.27%) than those in the younger age group (PM10 and PM2.5, 0.80% and 1.39%). PM concentration was associated with recurrent falls even after accounting for other regional variables and individual-level differences. Moreover, there were regional differences in the occurrence of falls, and the PM concentration explained a part of the gap, but the gap was explained more in the older group than in the young.

Роль вербальной репрезентации в оценке категориальных суждений

The study examines the role of inner speech measured by verbal representation scale in assessment of category judgments and in transfer from the category example to the whole category. We used the conventionality effect of the category label, meaning that people perceive judgments containing commonly used category labels as more convincing even when the category itself is new, and its label is artificial [11]. We proposed that this effect can be enhanced if to use a metaphorical label for the category that emphasizes its feature. We also tested whether the metaphorical label could enhance the transfer of the feature from the category example to the whole category. We hypothesized that the conventionality effect and transfer of the trait will be different in participants depending on their level of verbal representation. In the first part of the study, we adapted the Internal Representation Questionnaire [16] and used verbal representation scale from it to divide participants into groups by their level of inner speech. The results show that participants with higher level of verbal representation were less influenced by the conventionality effect of the label. We also found that participants with lower level of verbal representation were more prone to transfer information of the metaphorical labels. Otherwise, participants with higher level of verbal representation were more inclined to transfer category information of non-metaphorical labels. The findings indicate the relationship between individual differences in verbal representation level and evaluation of category judgments.

Abstract PO-137: Comparative transcriptomic analysis of prostate cancer from African American and Caucasian American men by Gleason score and race

Abstract African American (AA) men exhibit 2-3 times higher mortality from prostate cancer compared with Caucasian American (CA) men. Factors contributing to the disparity include societal-, neighborhood- and institutional-level determinants of health. In addition, a number of studies have reported individual-level ancestry-related biological differences, including in mutations, copy number variation, aggregate gene expression and response to treatment between AA and CA prostate cancer patients. Previously, by comparing the transcriptome between 20 AA and 15 CA prostate cancer patients, we identified a large number of race-related Alternative RNA Splicing (ARS) events. Among these, we further demonstrated that an exon skipping event involving exon 20 within PIK3CD increased tumor growth rate, metastatic potential and drug resistance in prostate cancer. To expand our previous findings, we collected non-neoplastic and tumor-paired tissue from 37 AA and 40 CA prostate cancer patients with different Gleason score categories: 14 high grade (4 AA and 10 CA), 22 low grade (10 AA and 12 CA), and 41 intermediate grade (23 AA and 18 CA). DNA and RNA were isolated for ancestral genotyping and RNA seq analysis, respectively. To achieve RNA sequencing depth adequate for ARS analysis, we performed RNA seq of 150 bp paired-end and an average of 5 × 106 reads per sample. The read alignment was done using Star 2 TwoPass pipeline. The rMATS pipeline was used for ARS annotation and quantification. We identified 105,403 ARS events, including 60,657 exon skipping, 17,439 alternative acceptor, 12,737 alternative donor, 9,555 retained intron and 5,015 mutually exclusive exon. Using the Wilcoxon rank-sum test, we compared the Percent Spliced In (PSI) between AA and CA of the same Gleason score category and identified ARS events exhibiting ΔPSI > 15% and p-value < 0.05. Specifically, we identified 536 race-related ARS events in high grade, 492 race-related ARS events in low grade, and 447 race-related ARS events in intermediate grade. Gene Ontology analysis demonstrated that the genes undergoing race-related ARS events function in cellular processes relevant to cancer biology, including metabolic processes in low grade, NF-kappaB signaling in intermediate grade and cell motility in high grade. Specific examples of these genes include ERG and PARP2 in high grade, KLK2 and DNMT1 in intermediate grade, and AURKA and SEMA3A in low grade. These findings support a potential role for the ARS process in diversifying gene expression, potentially contributing to prostate cancer aggressiveness in AA patients. The race-related ARS events identified in our work represent potential biomarkers and/or therapeutic targets for precision oncology in the context of prostate cancer. Further analysis of the function of prioritized race-related ARS events and their association with local ancestry is ongoing. Funding: DoD Prostate Cancer Research Program Health Disparity Research Award. NIH Basic Research in Cancer Health Disparities R01 Award. Prostate Cancer Foundation Movember Challenge Award. Citation Format: Muthana Al Abo, Wen-Chi Foo, Daniel J. George, Steven R. Patierno, Jennifer A. Freedman. Comparative transcriptomic analysis of prostate cancer from African American and Caucasian American men by Gleason score and race [abstract]. In: Proceedings of the AACR Virtual Conference: 14th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2021 Oct 6-8. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2022;31(1 Suppl):Abstract nr PO-137.

РОЛЬ ПОЛИМОРФНЫХ ЛОКУСОВ ГЕНОВ МОНОАМИНЕРГИЧЕСКИХ СИСТЕМ В ФОРМИРОВАНИИ АГРЕССИВНОСТИ У ЗДОРОВЫХ ИНДИВИДОВ

Aggressive behavior is an integral part of the human psyche. However, environmental risk factors, mental illness and somatic diseases can cause increased aggression, which represents the biological basis of antisocial behavior in a human society. An important role in the development of aggressive behavior belongs to the hereditary factors, that are probably related to abnormal functioning of neurotransmitter systems in the brain. However, the underlying genetic mechanisms remain unclear. The present study aimed to assess the main effects of monoaminergic systems gene polymorphisms (serotonergic - SLC6A4 , HTR2A , HTR1B, dopaminergic - DRD4 , MAOB ) together with haplotypic and gene-environmental effects on individual differences in aggression level in 642 mentally healthy individuals with sex and ethnicity inclusion as covariates. Aggression level was assessed using the Russian version of the Buss-Perry Aggression Questionnaire. The genotyping of the SLC6A4 ( 5-HTTLPR and rs1042173 ), HTR2A ( rs7322347 ), HTR1B ( rs13212041 ), DRD4 ( rs1800955 ), MAOB ( rs6651806 ) gene polymorphisms was conducted via polymerase chain reaction (real time and restriction fragment length polymorphism analysis). Statistical analysis included multiple linear/logistic regression (PLINK v. 1.9). The correction for multiple testing was conducted by the FDR procedure (False Discovery Rate). Statistical analysis revealed the association of SLC6A4 5-HTTLPR S -allele with an increased aggression level in men (pFDR = 0.022) and in Udmurts (pFDR = 0.009). In addition, we revealed that paternal care significantly affected association of SLC6A4 rs1042173 and aggression level (p = 0.001). The study demonstrated environmental, genderand ethnicity-specific role of the SLC6A4 gene in individual differences in aggression level in mentally healthy individuals.

Use-dependent corticospinal excitability is associated with resilience and physical performance during simulated military operational stress.

Simulated military operational stress (SMOS) provides a useful model to better understand resilience in humans as the stress associated with caloric restriction, sleep deficits, and fatiguing exertion degrades physical and cognitive performance. Habitual physical activity may confer resilience against these stressors by promoting favorable use-dependent neuroplasticity, but it is unclear how physical activity, resilience, and corticospinal excitability (CSE) relate during SMOS. To examine associations between corticospinal excitability, physical activity, and physical performance during SMOS. Fifty-three service members (age: 26 ± 5 yr, 13 women) completed a 5-day and -night intervention composed of familiarization, baseline, SMOS (2 nights/days), and recovery days. During SMOS, participants performed rigorous physical and cognitive activities while receiving half of normal sleep (two 2-h blocks) and caloric requirements. Lower and upper limb CSE were determined with transcranial magnetic stimulation (TMS) stimulus-response curves. Self-reported resilience, physical activity, military-specific physical performance (TMT), and endocrine factors were compared in individuals with high (HIGH) and low CSE based on a median split of lower limb CSE at baseline. HIGH had greater physical activity and better TMT performance throughout SMOS. Both groups maintained physical performance despite substantial psychophysiological stress. Physical activity, resilience, and TMT performance were directly associated with lower limb CSE. Individual differences in physical activity coincide with lower (but not upper) limb CSE. Such use-dependent corticospinal excitability directly relates to resilience and physical performance during SMOS. Future studies may use noninvasive neuromodulation to clarify the interplay among CSE, physical activity, and resilience and improve physical and cognitive performance.NEW & NOTEWORTHY We demonstrate that individual differences in physical activity levels coincide with lower limb corticospinal excitability. Such use-dependent corticospinal excitability directly relates to resilience and physical performance during a 5-day simulation of military operational stress with caloric restriction, sleep restriction and disruption, and heavy physical and cognitive exertion.

P.0110 Relationship between individual circadian rhythm and microrna level differences in mood disorders

P.0110 Relationship between individual circadian rhythm and microrna level differences in mood disorders

Breast Tissue Density Influences Tumor Malignancy Perception and Decisions in Mammography

High density breast tissue has been found to reduce radiologists’ accuracy in detecting and classifying mammogram abnormalities. The current research examines the perceptual and decisional components that underlie diagnostic classification (independent of detection) in a sample of novices. Mammograms were varied along two dimensions: Breast tissue density (low/high) and the nature of an identified mass (benign/malignant). In two experiments, participants learned to classify images into 4 categories created by factorial combination of these dimensions. In low density tissue, accuracy was higher for benign than for malignant masses. Surprisingly, and in contrast to the mammography literature, accuracy for malignant masses was higher in high-density than in low-density tissue. Cognitive modeling based in general recognition theory (GRT) indicated that low-density/benign category accuracy was largely due to high perceptual discriminability for that category. The high accuracy level for malignant masses in high density tissue was accounted for by decision bound slopes that favored the “malignant” response for items in the high-density malignant category. Because GRT can provide insight into perceptual and decisional determinants of observed classification accuracy, as well as individual-difference level parameters about attention allocation, GRT may be a means to obtain a more detailed understanding of diagnostic classification of complex naturalistic stimuli.

Ask a Political Scientist: A Conversation with Efrén Pérez about Political Psychology and the Study of Race and Ethnic Politics

Ask a Political Scientist: A Conversation with Efrén Pérez about Political Psychology and the Study of Race and Ethnic Politics

Employee motivation profiles, energy levels, and approaches to sustaining energy: A two-wave latent-profile analysis

Human energy is often viewed as a limited resource, that is depleted through effort expenditure at work, and subsequently needs to be replenished either during or after working. Self-determination theory, however, argues that individuals vary in the degree to which work is experienced as draining: autonomous motivation makes work seem effortless; while controlled motivation makes it effortful. As employees can endorse multiple motivations for work, we examined how motivation profiles are associated with energy levels directly and indirectly through approaches to sustaining energy (i.e., energy management strategies and recovery experiences). Latent profile analysis with two-wave data revealed four profiles (i.e., amotivated, amotivated/external, highly motivated, and autonomous). Time 1 employee motivation profiles were used to predict outcomes at Time 1 (N = 551) and Time 2 (N = 391). Overall, amotivated employees had the lowest energy levels and autonomous employees the highest (i.e., more vigor, less exhaustion, less need for recovery). Autonomous and highly motivated employees used more work-related energy management strategies and less detachment, compared to the other profiles. The differential use of work-related strategies partially explained differences in vigor by Time 2. Profiles that used relatively less detachment experienced less favorable energy levels over time. Interestingly, by Time 2, autonomous employees detached more than highly motivated employees, which explained their increased vigor over time. Taken together, our research shows that employee motivation can explain individual differences in energy levels as well as approaches to sustaining energy. Advice on how to manage energy and recovery would benefit from considering the configuration of employee motivation.

Do state supports for persons with brain injury affect outcomes in the 5Years following acute rehabilitation?

While a substantial literature has examined the effects of individual and family-level factors on outcomes following traumatic brain injury (TBI), minimal attention has been directed to the potential influence of the larger environmental context on outcomes. The purpose of the current study was to investigate the effects of state-level resources and supports as an environmental factor influencing long-term outcomes from TBI using data from the TBI Model Systems. We examined the effects of U.S. state supports that specifically target people with TBI (federal funding for state brain injury programs, per capita revenue generated by brain injury trust funds, and expenditures for brain injury specific Medicaid waivers) and one measure of the relative quality of a state's Long-Term Services and Supports (LTSS) for all people with disabilities. The primary hypothesis was that community participation, global functioning, and life satisfaction will be higher on average among people with TBI living in states with more brain injury specific programs and resources and better LTSS. The results of multilevel and fixed-effects modeling indicated that state supports have a small but significant impact on participation and life satisfaction. The most consistent finding indicated that states with better LTSS had higher levels of community participation and life satisfaction on average for people with TBI over and above individual-level differences and fluctuations in these outcomes over time. There was some indication that more brain injury specific supports also result in better participation in the community. These findings deserve replication and extension to include other environmental factors, particularly community level characteristics, that might affect outcomes from TBI.

Individual shedder status and the origin of touch DNA

Due to improved laboratory techniques, touched surfaces and items are increasingly employed as sources of forensic DNA evidence. This has urged a need to better understand the mechanisms of DNA transfer between individuals. Shedder status (i.e. the propensity to leave DNA behind) has been identified as one major factor regulating DNA transfer. It is known that some individuals tend to shed more DNA than others, but the mechanisms behind shedder status are largely unknown. By comparing the amounts of DNA deposited from active hands (i.e. used “as usual”) and inactive hands (i.e. not allowed to touch anything), we show that some of the self-DNA deposited from hands is likely to have accumulated on hands from other parts of the body or previously handled items (active hands: 2.1 ± 2.7 ng, inactive hands: 0.83 ± 1.1 ng, paired t-test: p = 0.014, n = 27 pairs of hands). Further investigation showed that individual levels of deposited DNA are highly associated with the level of DNA accumulation on the skin of the face (Pearson’s correlation: r = 0.90, p < 0.00001 and Spearman’s ranked correlation: rs = 0.56, p = 0.0016, n = 29). We hypothesized that individual differences in sebum secretion levels could influence the amount of DNA accumulation in facial areas, but no such correlation was seen (Pearson’s correlation: r = − 0.13, p = 0.66, n = 14). Neither was there any correlation between DNA levels on hands or forehead and the time since hand or face wash. We propose that the amount of self-DNA deposited from hands is highly influenced by the individual levels of accumulated facial DNA, and that cells/DNA is often transferred to hands by touching or rubbing one’s face.

How do policy levers shape the quality of a national health system?

Poor quality of care may have a detrimental effect on access and take-up and can become a serious barrier to the universality of health services. This consideration is of particular interest in view of the fact that health systems in many countries must address a growing public-sector deficit and respond to increasing pressures due to COVID-19 and aging population, among other factors. In line with a rapidly emerging literature, we focus on patient satisfaction as a proxy for quality of health care. Drawing on rich longitudinal and cross-sectional data for Spain and multilevel estimation techniques, we show that in addition to individual level differences, policy levers (such as public health spending and the patient-doctor ratio, in particular) exert a considerable influence on the quality of a health care system. Our results suggest that policymakers seeking to enhance the quality of care should be cautious when compromising the level of health resources, and in particular, health personnel, as a response to economic downturns in a sector that traditionally had insufficient human resources in many countries, which have become even more evident in the light of the current health crisis. Additionally, we provide evidence that the increasing reliance on the private health sector may be indicative of inefficiencies in the public system and/or the existence of features of private insurance which are deemed important by patients.

Regulating mirroring of emotions: A social-specific mechanism?

There is evidence that humans mirror others’ emotional responses: brain responses to observed and experienced emotion overlap, and reaction time costs of observing others’ pain suggest that others’ emotional states interfere with our own. Such emotional mirroring requires regulation to prevent personal distress. However, currently it is unclear whether this “empathic interference effect” is uniquely social, arising only from the observation of human actors, or also from the observation of non-biological objects in “painful” states. Moreover, the degree to which this interference relates to individual differences in self-reported levels of empathy is yet to be revealed. We introduce a modified pain observation task, measuring empathic interference effects induced by observation of painful states applied to both biological and non-biological stimuli. An initial validation study (N = 50) confirmed that painful states applied to biological stimuli were rated explicitly as more painful than non-painful states applied to biological stimuli, and also than both painful and non-painful states applied to non-biological stimuli. Subsequently, across two independent discovery (N = 83) and replication (N = 80) samples, the task elicited slowing of response times during the observation of painful states when compared to non-painful states, but the magnitude of this effect did not differ between biological and non-biological stimuli. Little evidence was found for reliable relationships between empathic interference and self-reported empathy. Caution should therefore be taken in using the current task to pursue an individual differences approach to empathic interference, but the task shows promise for investigating the specificity of the mechanism involved in regulating emotional mirroring.

Assessing individual environmental exposure derived from the spatiotemporal behavior context and its impacts on mental health.

Research on the associations between environmental exposures and mental health has attracted considerable attention. Most studies to date have mainly estimated environmental health effects based on static geographic contexts (e.g., residential neighborhoods, administrative units), ignoring the dynamic nature of individual spatiotemporal behavior, which may lead to unreliable results. To address this limitation, this study collects survey data from 1003 adults in Guangzhou, China. Then, it delineates dynamic geographic context to capture individual daily activity and travel and assesses individual exposure to environmental factors derived from the home buffer (HB) and the time-weighted activity and travel buffer (TATB). Finally, multiple linear regression models are used in this paper to examine and compare the relationships between individual environmental exposure and mental health based on the HB and TATB. The results of this study indicate that there are great differences in individual environmental exposure levels based on the HB and TATB. The explanatory power of the environmental factors obtained from the TATB on mental health is greater than that derived from the HB. Specifically, exposures to some environmental factors (i.e., green space coverage, blue space coverage, fitness facility density, and recreational facility density) derived from the TATB have mental health-promoting effects, while exposures to the other environmental factors (i.e., public transit station density) have mental health-constraining effects. These findings enrich our knowledge of spatiotemporal behavior and the effects of the dynamic contextual environment on mental health, as well as provide valuable implications for urban planning and public health service.

Individual differences in representational similarity of first and second languages in the bilingual brain.

Current theories of bilingualism disagree on the extent to which separate brain regions are used to maintain or process one's first and second language. The present study took a novel multivariate approach to address this question. We examined whether bilinguals maintain distinct neural representations of two languages; specifically, we tested whether brain areas that are involved in processing word meaning in either language are reliably representing each language differently, and whether language representation is influenced by individual differences in proficiency level and age of acquisition (AoA) of L2. Thirty‐one English–Mandarin bilingual adults performed a picture–word matching task in both languages. We then used representational similarity analysis to examine which brain regions reliably showed different patterns of activity for each language. We found that both proficiency and AoA predicted dissimilarity between language representations in several brain areas within the language network as well as several regions of the ventral visual pathway, demonstrating that top‐down language knowledge and individual language experience shapes concept representation in this processing stream. The results support the model of an integrated language system in bilinguals, along with a novel description of how representations for each language change with proficiency level and L2 AoA.

Linked fate among underrepresented groups: Investigating the relationships between Black college students’ perceptions of institutional diversity climate and mental health

Objective: Negative perceptions of institutional racial climate relate to worse mental health outcomes for Black college students. Yet, few scholars have considered how Black students’ perceptions of the institutional climate for other underrepresented groups may impact mental health. Participants and Methods: We drew on a national sample of Black college students across 15 institutions (n = 1188) to examine the effects of institutional diversity climate on students’ anxiety, depression, and positive mental health. Results: Black students who perceived the campus as more welcoming to first-generation reported higher positive mental health. Black students who perceived the campus as more welcoming to racial minorities, lesbian, gay, bisexual (LGB), and low socioeconomic status (SES) students reported lower levels of depression and anxiety. Conclusions: Black students’ perceptions of the institutional diversity climate for other groups influences their mental health outcomes, and underscores the need for more research on individual-level differences in students’ mental health processes.