Individual Differences In Avoidance Research Articles

Individual differences in costly fearful avoidance and the relation to psychophysiology

Excessive avoidance behaviour is a cardinal symptom of anxiety disorders. Avoidance is not only associated with the benefits of avoiding threats, but also with the costs of missing out on rewards upon exploration. Psychological and psychophysiological mechanisms contributing to these costly avoidance decisions in prospect of mixed outcomes remain unclear. We developed a novel Fearful Avoidance Task (FAT) that resembles characteristics of real-life approach-avoidance conflicts, enabling to disentangle reward and threat effects. Using the FAT, we investigated individual differences in avoidance behaviour and anticipatory psychophysiological states (i.e. startle reflex and skin conductance) in a relatively large sample of 343 (78 females) participants. Avoidance under acute threat of shock depends on a trade-off between perceived reward and threat. Both increased startle and skin conductance in the absence of threat of shock emerged as predictors of increased avoidance (potentially indicative of fear generalization). Increased avoidance was also associated with female sex and trait anxiety, dependent on reward and threat levels. Our findings highlight distinct possible predictors of heightened avoidance and add to mechanistic understanding of how individual propensity for costly avoidance may emerge. Distinct avoidance typologies based on differential reward and threat sensitivities may have different mechanistic origins and thereby could benefit from different treatment strategies.

Avoiding information about one’s romantic partner

Research links open communication and self-disclosure to a host of beneficial outcomes in romantic relationships, including better relationship quality, relationship satisfaction, feelings of closeness and commitment, and relationship longevity. However, learning some information about a partner may evoke negative consequences. In two studies, we examined the types of information people may wish to avoid learning about their past or current romantic partners (Study 1), and individual differences in avoidance of information about a current romantic partner (Study 2). Content-coding of data from Study 1 revealed that a majority (51%) of respondents wished to avoid information related to their partner’s history of sexual behavior and/or infidelity. In Study 2, participants who were older and who scored higher on measures of anxious and avoidant attachment were more likely to want to avoid information about their partner. Furthermore, replicating and extending Study 1, participants most wished to avoid information about their partners’ prior sexual behavior and/or infidelity, as well as their partners’ prejudices. We interpret our findings in terms of a threat-management framework for information avoidance, suggesting that threats to the self and relationship may influence the decision to avoid information about a romantic partner.

The COMT Val158Met Polymorphism and Reaction to a Transgression: Findings of Genetic Associations in Both Chinese and German Samples.

After a transgression, people often either tend to avoid the transgressor or seek revenge. These tendencies can be investigated via a trait approach and surprisingly little is known about their biological underpinnings. One promising candidate gene polymorphism, which may influence individual differences in avoidance of a transgressor and vengefulness, is the COMT Val158Met (rs4680) polymorphism known to affect dopaminergic signaling and among others brain activity in situations in which people punish others for their behavior. We therefore investigated the molecular genetics of individual differences in Avoidance Motivation and vengefulness with a focus on this polymorphism. Possible genetic associations were first investigated in a sample of N = 730 Chinese participants (n = 196 females) using buccal cells to extract the DNA for genotyping. To replicate the findings we carried out a parallelized investigation in a sample of N = 585 German participants (n = 399 females). Chinese and German versions of the TRIM-12 and the Vengeance Scale were implemented to assess individual differences in tendencies to react to a transgression. Results show that Met allele carriers of the COMT Val158Met polymorphism (Val/Met and Met/Met) score significantly higher on the tendency to avoid a transgressor in the Chinese male and female samples, with an especially pronounced effect in the female subgroup. The same effect could be found in the German sample, again especially in females. Additionally, carrying a Met allele was associated with higher vengefulness in the Chinese sample only, especially in males. The present findings indicate that the COMT Val158Met polymorphism might influence individual differences in the motivation to avoid transgressors across cultures, especially in females. However, its association with vengefulness seems to be more complex and may exhibit some cultural and gender specific effects.

Assessment of individual differences in the rat nucleus accumbens transcriptome following taste-heroin extended access.

Heroin addiction is a disease of chronic relapse that harms the individual through devaluation of personal responsibilities in favor of finding and using drugs. Only some recreational heroin users devolve into addiction but the basis of these individual differences is not known. We have shown in rats that avoidance of a heroin-paired taste cue reliably identifies individual animals with greater addiction-like behavior for heroin. Here rats received 5min access to a 0.15% saccharin solution followed by the opportunity to self-administer either saline or heroin for 6h. Large Suppressors of the heroin-paired taste cue displayed increased drug escalation, motivation for drug, and drug loading behavior compared with Small Suppressors. Little is known about the molecular mechanisms of these individual differences in addiction-like behavior. We examined the individual differences in mRNA expression in the nucleus accumbens (NAc) of rats that were behaviorally stratified by addiction-like behavior using next-generation sequencing. We hypothesized that based on the avoidance of the drug-paired cue there will be a unique mRNA profile in the NAc. Analysis of strand-specific whole genome RNA-Seq data revealed a number of genes differentially regulated in NAc based on the suppression of the natural saccharine reward. Large Suppressors exhibited a unique mRNA prolife compared to Saline controls and Small Suppressors. Genes related to immunity, neuronal activity, and behavior were differentially expressed among the 3 groups. In total, individual differences in avoidance of a heroin-paired taste cue are associated with addiction-like behavior along with differential NAc gene expression.

Food risk perceptions, gender, and individual differences in avoidance and approach motivation, intuitive and analytic thinking styles, and anxiety

Risks appear to be perceived in two different ways, affectively and rationally. Finnish adult internet users were contacted via e-mail and asked to fill an internet questionnaire consisting of questions of food risks and measures of avoidance and approach motivation, analytic and intuitive information processing style, trait anxiety, and gender in order to find out (1) whether food risks are perceived two-dimensionally, (2) how individual differences in motivation, information processing, and anxiety are associated with the different dimensions of food risk perceptions, and (3) whether gender moderates these associations. The data were analyzed by factor, correlation and regression analyses. Three factors emerged: risk scariness, risk likelihood, and risks of cardiovascular disease. Personality and gender x personality interactions predicted food risk perceptions. Results showed that food risk perceptions generally form two dimensions; scariness and likelihood, but that this may depend on the nature of the risk. In addition, results imply that individuals with high avoidance motivation perceive food risks as scarier and more likely than others, and that individuals with an analytic information processing style perceive food risks as less likely than others. Trait anxiety seems to be associated with higher food risk perceptions only among men.