You have accessJournal of UrologyKidney Cancer: Evaluation and Staging II1 Apr 2012707 EXAMINING THE UTILITY OF THE R.E.N.A.L. NEPHROMETRY SCORING SYSTEM AS A PREDICTOR OF THE EFFICACY OF NEPHRON-SPARING SURGERY IN THE SOLITARY KIDNEY David Buethe, Sammy Moussly, Hui-Yi Lin, Xiuhua Zhao, Philippe Spiess, and Wade Sexton David BuetheDavid Buethe Tampa, FL More articles by this author , Sammy MousslySammy Moussly Tampa, FL More articles by this author , Hui-Yi LinHui-Yi Lin Tampa, FL More articles by this author , Xiuhua ZhaoXiuhua Zhao Tampa, FL More articles by this author , Philippe SpiessPhilippe Spiess Tampa, FL More articles by this author , and Wade SextonWade Sexton Tampa, FL More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2012.02.791AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES Recently, the R.E.N.A.L. nephrometry scoring system was introduced to objectively describe renal masses with respect to size, the degree to which they are exo/endophytic, the nearness to the collecting system, whether they are anterior or posterior and the location relative to polar lines. It is our aim to evaluate the R.E.N.A.L. nephrometry scoring system's ability to predict functional renal loss attributed to nephron−sparing surgery (NSS). METHODS We evaluated 42 patients presenting with either an anatomic (32) or functionally solitary (10) kidney undergoing partial nephrectomy (PN). Each renal unit was assigned a R.E.N.A.L. nephrometry score utilizing pre-operative cross−sectional imaging. The CKD−EPI equation was applied to serum creatinine levels to generate corresponding estimated glomerular filtration rates (eGFR). The difference between the eGFR at baseline and at post−operative time points served as a measurement of renal function loss attributed to PN. RESULTS Forty−two patients underwent PN with mean pre− operative eGFR of 61.5 mL/min/1.73m2. The median total nephrometry score was 8, ranging from 4−10. Twenty−eight (66.7%) of the renal lesions were ¡Ü 4 cm, 13 (31%) were between 4 and 7 cm, and 1 (2.4%) was >7 cm in diameter. The majority (54.8%) of the patients had tumors with more than 50% of tumor burden lying outside the expected renal border whereas 3 patients (7.1%) had tumors considered to be completely endophytic. Twenty−seven (64.3%) were within 4 mm of the collecting system. Tumor locations defined as: completely polar, interpolar, and completely central were assigned to 11, 15, and 16 lesions respectively. By post−operative month 6, the overall average eGFR of 53.9 mL/min/1.73m2 (a 12.3% reduction) was significantly less (p = 0.0293) than the pre−operative value. However, we were unable to correlate a change in eGFR with the pre-operatively assigned individual component scores nor the total R.E.N.A.L. score. CONCLUSIONS Neither the individual components of the R.E.N.A.L. nephrometry scoring system nor the total nephrometry score correlated with realized functional loss as assessed by percent change in eGFR in patients with a solitary kidney undergoing NSS. © 2012 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 187Issue 4SApril 2012Page: e290 Advertisement Copyright & Permissions© 2012 by American Urological Association Education and Research, Inc.MetricsAuthor Information David Buethe Tampa, FL More articles by this author Sammy Moussly Tampa, FL More articles by this author Hui-Yi Lin Tampa, FL More articles by this author Xiuhua Zhao Tampa, FL More articles by this author Philippe Spiess Tampa, FL More articles by this author Wade Sexton Tampa, FL More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...