Research In India Research Articles

First record of the phoretic association between Pediculaster sp. (Pygmephoridae) mites and Musca crassirostris (Muscidae) flies in India

This article reports for the first time a phoretic pygmephorid mite on a muscid fly from India, with pygmephorid mites classified under the order Prostigmata and the family Pygmephoridae. The mites, identified as species of the genus Pediculaster belonging to the family Pygmephoridae, were collected in July 2019 from Khajjiar town, located in the Chamba district of Himachal Pradesh, India. The flies, identified as Musca crassirostris belonging to the family Muscidae, were also noted. While this study marks a significant step in Indian research, further investigation is warranted to comprehensively compile data on the species accuracy of mites and their habitat preferences.

The rise of Indo-German collaborative research: 1990–2022

Purpose This study aims to highlight the growth and development of Indo-German collaborative research over the past three decades. Moreover, this study encompasses an in-depth examination of funding acknowledgements to gain valuable insights into the financial support that underpins these collaborative endeavours. Together with this paper, the authors provide an openly accessible data set of Indo-German research papers for further and reproducible research activities (the “Indo-German Literature Dataset”). Design/methodology/approach The data were retrieved from the Web of Science (WoS) database from the year 1990 till the 30th of November 2022. A total of 36,999 records were retrieved against the used query. Acknowledged entities were extracted using a named entity recognition (NER) model specifically trained for this task. Interrelations between the extracted entities and scientific domains, lengths of acknowledgement texts, number of authors and affiliations, number of citations and gender of the first author, as well as collaboration patterns between Indian and German funders were examined. Findings The study reveals a consistent and increasing growth in the publication trend over the years. The study brings to light that Physics, Chemistry, Materials Science, Astronomy and Astrophysics and Engineering prominently dominate the Indo-German collaborative research. The USA, followed by England and France, are the most active collaborators in Indian and German research. Largely, research was funded by major German and Indian funding agencies, international corporations and German and American universities. Associations between the first author’s gender and acknowledged entity were observed. Additionally, relations between entity, entity type and scientific domain were discovered. Practical implications The study paves the way for enhanced collaboration, optimized resource utilization and societal advantages by offering a profound comprehension of the intricacies inherent in research partnerships between India and Germany. Implementation of the insights gleaned from this study holds the promise of cultivating a more resilient and influential collaborative research ecosystem between the two nations. Originality/value The study highlights a deeper understanding of the composition of the Indo-German collaborative research landscape of the past 30 years and its significance in advancing scientific knowledge and fostering international partnerships. Furthermore, the authors provide an open version of the original WoS data set. The Indo-German Literature Data set consists of 22,844 papers from OpenAlex and is available for related studies like literature studies and scientometrics.

Computational Mapping of Indian Organic Chemistry Research: An Analysis with Data Mining Tools

Computational Mapping of Indian Organic Chemistry Research: An Analysis with Data Mining Tools

Strengthening research capacity of early-mid career researchers: Implementation and evaluation of the Excellence in Non-COmmunicable disease REsearch (ENCORE) program.

High-quality training and networking are pivotal for enhancing the research capacity of early- to mid-career researchers in the prevention and control of non-communicable diseases. Beyond building research skills, these professionals gain valuable insights from interdisciplinary mentorship, networking opportunities, and exposure to diverse cultures and health systems. Despite the significance of such initiatives, their implementation remains underexplored. Here, we describe the implementation and evaluation of the Excellence in Non-COommunicable disease REsearch (ENCORE) program, a collaborative initiative between Australia and India that was launched in 2016 and spanned a duration of 3 years. Led by a consortium that included the University of Melbourne and leading Indian research and medical institutions, ENCORE involved 15 faculty members and 20 early-mid career researchers. The program comprised various elements, including face-to-face forums, masterclasses, webinars, a health-technology conference, and roundtable events. ENCORE successfully trained the early-career researchers, resulting in over 30 peer-reviewed articles, 36 conference presentations, and the submission of seven grant applications, three of which received funding. Beyond individual achievements, ENCORE fostered robust research collaboration between Australian and Indian institutions, showcasing its broader impact on strengthening research capacities across borders.

A CRITICAL REVIEW OF KARAVELLAKA (MOMORDICA CHARANTIA LINN.) AS A VISHAGNA DRAVYA (ANTI POISONOUS DRUG)

BACKGROUND: Our ancestors know the day-to-day common and medicinal uses of Karavellaka (Momordica charantia Linn.). It is also known to be utilised by folklore practitioners for medicinal purposes. MATERIALS AND METHODS: Here is an attempt made to gather information about Karavellaka as Vishagna through the literary resources from various classical and contemporary texts and other publications like Kriyakaumudi, Indian Medicinal Plants, Rasatarangini and research updates. OBSERVATION AND RE-SULT: The reference to Vishagna property is available in the classics and is supported by research articles. CONCLUSION: Studies prove the (Vishagna) anti-poisonous activity of Karavellaka utilised either Ekamoolika Dravya or another form of Aushadhi Yoga and expanded the scope of exploration of its medicinal benefits.

Authenticity: Conceptual Analysis and Relevance in the Indian Sociocultural Context

This article attempts to understand the concept of psychological authenticity, identifies gaps in the literature, and emphasizes its significance in the Indian context. Studies on authenticity in global and Indian contexts were reviewed for this purpose and the multifacetedness of the concept was specifically highlighted. A comparison of Indian and Western accounts of authenticity shows that Indian researchers are more prescriptive while defining the authentic self than their Western counterparts, who have provided descriptive accounts of authenticity. Sociocultural factors impact authenticity, but whether they enrich or hinder authenticity across contexts is unclear. Factors such as fear of negative evaluation or the need for belongingness are expected to impact the expression of authenticity at the behavioral level in the unique sociocultural context of India. Considering context-specific factors, the process of becoming authentic is more central to understanding authenticity than perceiving it as an end state of being. This discussion shows that authenticity as a construct is yet to be adequately explored globally, as well as in the Indian sociocultural context. Future research on authenticity holds great promise in areas related to mental health and personality.

Sexual dysfunction in men with young onset Parkinson's disease.

Sexual dysfunction (SD) is a common, yet under-reported non-motor symptom of PD. Common sexual symptoms among male PD patients include erectile dysfunction, premature ejaculation, and decreased sexual desire. Few research papers have examined sexual dysfunction in PD, especially in YOPD male patients, and there is no Indian research study on sexual dysfunction in YOPD. In this study, we determined the frequency of sexual dysfunction in men with YOPD, and its correlation with other motor and NMS. This prospective cross-sectional study was conducted on YOPD males who presented to the Department of Neurology, NIMHANS, Bangalore, India, from May 2021 to April 2023. The diagnosis of YOPD was made based on MDS criteria for IPD 2015. Sexual functions were evaluated by ASEX, PEDT, QUIP-RS, and sex hormone assay. The patients also underwent other motor and non-motor assessments. Statistical analysis was done using SPSS version 22.0. The study was funded by the PDMD fund. This study included 62 male YOPD patients. The mean age of cases was 44.74 ± 8.54years. The mean duration of symptoms was 8.45 ± 6.23years. 43.5% of the cases of PD were Akinetic rigid type. By ASEX Score grading, 46.8% of the cases had erectile dysfunction and 71% of the cases of YOPD had premature ejaculation by PEDT Score grading. 9.7% of the cases had hypersexuality by QUIP-RS.Duration of YOPD was a better predictor of Erectile Dysfunction and premature ejaculation when compared with other variables. SD was related to anxiety and depression and it had a negative impact on the patient's health-related quality of life (HR-QoL). SD should be investigated and treated as an integral part of the neurological assessment in YOPD.

TRAILBLAZERS OF MEDICAL KNOWLEDGE IN ANCIENT INDIA, WHO HAVE SHAPED THE MEDICAL SCIENCE

The ancient sages contributed intricate knowledge of disease’s causes and even described the likelihood of hereditary transmission pathways and how to cure the diseases. Ayurveda, ‘a natural medicine system’ for health care practices through the application of herbs and other materials, originated more than 5,000 years ago in India. The objective of the study is to examine the contributions of Sages, Acharyas, Maharishis, and Rishis in the medical field of ancient India and their impact on modern medicine. Method: The study is descriptive type by nature based basically on the data collected from different secondary sources. Findings: Indian medical knowledge spread throughout the world and it has remained and used as it was in the past or used in a modified way but remains its originality in some places of the world. Conclusion: Numerous Baidyas (Doctors) and Surgeons have made significant contributions to India's healthcare systems in ancient India. These outstanding ancient Indian medical researchers have made a lasting impact on a number of scientific fields. Their significant discoveries, ground-breaking theories, and profound insights continue to influence how we develop our healthcare practices.

Measuring the growth and impact of library and information science research in India: a multidimensional scientometric assessment

Purpose This study aims to provide insight into Library and Information Science (LIS) research in India using scientometric approaches. Web of Science (WoS) and SCOPUS databases were used for data retrieval. The study examines productivity in terms of source types, gender distribution, document formats, authorship and other factors. In addition, this study sought to identify trends or patterns in the research preferences of LIS scientists through text analysis. Design/methodology/approach Data were downloaded from the WoS and Scopus databases over 22 years and analysed using VOSviewer, Orange, Biblioshiny and CRExplorer softwares. Findings The findings reveal that 5,692 out of the 9,384 documents in both databases underwent the final examination. In total, 466 different sources produced all of those papers. Author analysis revealed that 6,603 different authors authored 5,692 documents. There were 4,209 male and 1,063 female authors. Furthermore, India shares maximum collaborations with the USA and England. The spectrogram features nine significant peaks corresponding to Lotka’s, Bradford’s and similar laws. Text analysis revealed that Indian LIS researchers have consistently investigated open access and digital or open libraries. Research limitations/implications The findings of this study will provide readers with a better understanding of India’s contribution to LIS. In addition, the study will help academics identify research gaps and undiscovered areas in the Indian context that require further investigation. Originality/value Not many studies highlight Indian research trends and international collaboration in LIS. This study highlights research trends, collaboration and gender productivity in LIS. The most cited references and trending topics were also identified using reference publication year spectroscopy and text analysis techniques.

Do Indian Researchers Consider Functioning Issues of Lower Extremity Osteoarthritis: A Scoping Review

Lower extremity osteoarthritis (LEOA) is a noncommunicable disease with an increasing burden globally, especially the developing countries like India. Understanding the functioning issue is needed to address individuals’ daily problems. Knowing how Indian researchers consider functioning will aid in understanding the current research trend. This scoping review describes the nature and extent to which the Indian researchers considered the functioning issues of LEOA individuals and linked them with the International Classification of Functioning, Disability, and Health (ICF) categories. We conducted an electronic database search of PubMed, Cochrane Library, and Pedro for Indian studies related to the functional issue of LEOA. Keeping the standard of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses- extension for scoping reviews (ScR) guidelines, we identified 102 related articles and included 28 that match the selection criteria. We observed a limited focus on functioning issues by Indian researchers. The researchers mainly rely on functional outcome measures while considering the functioning issue of LEOA. Most Western sociocultural influence outcome measures used by the studies were linked with activity limitation and participation restriction of ICF categories only. There is an urgent need for Indian researchers across professions to employ the ICF as a conceptual framework to understand and address the functioning issues associated with LEOA comprehensively.

Addressing the Pervasive Issue of Predatory Journals and Conferences: An Indian Researcher's Perspective.

Addressing the Pervasive Issue of Predatory Journals and Conferences: An Indian Researcher's Perspective.

A Bibliographic Analysis of Indian Contribution in Application of Presurgical Naso-Alveolar Molding in Cleft Lip/Palate Infants

Background: Pre-surgical nasoalveolar molding is a novel treatment modality applied in cleft lip/palate infants prior to surgery. Numerous articles have been published in the literature. Using Bibliographic analysis tt is essential to know the nation wise contribution of total research output towards PSNAM. Aim: To evaluate Indian contribution globally on the domain ‘application of presurgical naso-alveolar molding in cleft lip/palate infants’ by analysing all the studies published till date. Materials and Methods: A detailed bibliographic database search was carried out using PUBMED for a period of two months from September to October 2023. Different Mesh keywords in several combinations were used to obtain the articles. All types of published articles from inception till October 2023 and were published in English language were considered for this bibliographic analysis. The selected published articles pertaining to Indian Institutions, researchers or authors and specialties were tabulated and evaluated to obtain the overall bibliographic details. Results: India’s global contribution was 6.65% (total 31 articles). More number of case reports (n=15) were published followed by case control studies (n=5). Highest publication credit was conquered by author Thakur S (n=5) and Journal of Indian Prosthodontic Society and Contemporary clinical dentistry journals shared maximum articles published (n=5 each) having impact factor of 0.265 and 1.2 respectively. South zone contribution was highest (n=12) in that Karnataka state bagged with highest contribution. H.P. Government Dental College and Hospital and regarding specialty, Pediatric and Preventive Dentistry contributed more research work towards PSNAM. Conclusion: From the present bibliographic review, it was concluded that there is a growing demand and increasing trend in the application of PSNAM in cleft lip/palate infants. The current review provides insight into the current literature on PSNAM and paves for further research and its application in clinical practice

Identifying Employability skills for Indian doctoral researchers: A thematic analysis of the Supervisors' perception

Identifying Employability skills for Indian doctoral researchers: A thematic analysis of the Supervisors' perception

Heart rate variability and fasting plasma glucose as trait marker of psychosis: A comparative study between drug naive patients with psychosis and healthy volunteers

Abstract: BACKGROUND: To date, mixed results have been obtained regarding the metabolic and cardiovascular changes in drug-naïve psychotic patients. Moreover, very few Indian studies are available on this subject. The current study adds to the Indian research on metabolic and cardiovascular factors associated with psychotic disorders. AIM: The aim of the study is to determine that metabolic abnormalities such as “impaired glucose tolerance, abnormal lipid profile, and cardiovascular risks are associated with the pathophysiology of the disease itself, i.e., psychosis. MATERIALS AND METHODS: The present study was a hospital-based cross-sectional study conducted over 2 years that included 30 drug-naïve psychotic patients as per ICD-10 DCR and 20 healthy volunteers. Purposive sampling was done. The patients and matched healthy volunteers fulfilling the inclusion and exclusion criteria were assessed to obtain the sociodemographic data, and a mental state examination was done. Positive and Negative Syndrome Scale was applied to patients only. The required investigations, such as lipid profile, sugar profile, body mass index, and electrocardiogram (ECG) for root mean square standard deviation (RMSSD) (heart rate variability [HRV]-time domain), heart rate, and corrected QT interval, were done in both the groups after obtaining written informed consent. The ECGs of all subjects in both groups were obtained mostly in the morning between 10 am and 12 am. The subjects were asked to avoid coffee and nicotine for 1 h before the ECG recording. The patient was asked to rest for 10 min before the recording and 1 min 6-lead ECG recording was obtained in a supine position at complete rest. RMSSD was calculated from the reading of lead II on 1 min resting ECG. RESULTS: Most of the metabolic and cardiovascular factors showed no statistically significant difference between the two groups except fasting blood sugar (FBS) (t = 0.843, P = 0.033), and median value of HRV (P = 0.008). Mean FBS was higher in the patient group compared to the control, and mean HRV was lower in the patient group compared to the control. CONCLUSION: The findings of the current study, in conjunction with the findings from other methodologically similar studies, suggest that lower HRV and abnormal fasting glucose may be associated with the psychopathology of psychotic illnesses.

Historical and contemporary development of novel chemotype varieties with high essential oil of lemongrass in India: A review

Lemongrasses found in India encompass Cymbopogon flexuosus, C. citratus, C. khasianus, and C. pendulus. This fragrant perennial grass belongs to the Poaceae family and is indigenous to India as well as other tropical and subtropical regions in Southeast Asia and Africa. Pinpointing its precise place of origin is challenging due to its extensive history of cultivation and utilization across various cultures. It is believed to have originated in the maritime Southeast Asian region, encompassing countries like India, Sri Lanka, Indonesia, and Malaysia. Lemongrass thrives in these regions and has played a significant role in their culinary and medicinal traditions for many generations. Among these, Cymbopogon citratus, a tropical lemongrass variety, is native to multiple Asian regions, particularly Southeast Asia and South Asia. It is widely cultivated and employed in a range of global cuisines and traditional healing practices. Lemongrass finds extensive applications in the herbal, medicinal, cosmetic, pharmaceutical, and fragrance industries. Lemongrass oil is known for its diverse biological properties, which encompass antibacterial, immunomodulatory, and antioxidant effects. Not too long ago, India ranked as one of the world' leading exporters of lemongrass essential oil. Several prominent lemongrass cultivars have emerged, including GRL-1 (geraniol-rich), Krishna, Cauveri, Pragati, Praman, T-1, CIM Shikhar, Chirharit, CKP-25, SD-68, CIMAP Suwarna, and Krishnapriya. Among these, CIMAP Suwarna, Krishna, and CIM Shikhar stand out as the most widely favoured varieties across India developed at the CSIR-CIMAP in Lucknow, India. Indian universities and research institutions have also played a pivotal role in the development of novel lemongrass cultivars. Examples include Jor Lab L-2, OD-19, SD-68 (C. flexuosus), RRL-16 (C. pendulus), and CKP-25. Notably, there's Jor Lab L-9, a distinctive strain of C. khasianus known for its high methyl eugenol content. Furthermore, the germplasm for Malabar lemongrass (C. khasianus) is notable for its abundant herbage and elevated elemicin content, reaching up to 70%. The CSIR-NEIST in Jorhat and the CSIR-CIMAP, Lucknow have contributed to the development of new high geraniol-rich lemongrass cultivars, such as "Jor Lab L-15" (C. khasianus), GRL-1, and CIM Atal (C. flexuosus), respectively. b: citral, elemicin, geraniol, methyl eugenol content, vitamin A, Cymbopogon, flexuosus, Cymbopogon pendulus, Cymbopogon khasianus, Cymbopogon citratus, Lemongrass varieties Citral, Cymbopogon citratus, Cymbopogon flexuosus, Cymbopogon khasianus, Cymbopogon pendulus, Elemicin, Geraniol, Lemongrass varieties, Methyl eugenol content, Vitamin A

Retractions covered by retraction watch from 2017 to 2022: a perspective from Indian researchers

Purpose The purpose of this study is to examine characteristics of retracted publications from Indian authors and inspect a relationship between journal impact factor (JIF) and the number of authors (NoA). Design/methodology/approach The authors examined the general characteristics of retracted publications and investigated the correlation between JIF and NoA from Indian authors from January 1, 2017, to December 31, 2022. Data were mined from retraction watch http://retractiondatabase.org/ (n = 1,459) and determined the year of publication, year of retraction, authors, journals, publishers and causes of the retractions. A journal citation report was extracted to gather the JIFs. Findings About one-third of retracted papers were published in 2020; 2022 has the highest retraction rate (723); studies with two authors represent about one-third (476) of the published articles; Journal of Ambient Intelligence and Humanized Computing (354) has the highest number of retractions; Springer published the most retracted papers (674); and the majority of the journal (1,133) is indexed in journal citation reports, with impact factor extending from 0.504 to 43.474. Retraction due to legal reasons/legal threats was the most predominant reason for retraction. Originality/value This study reflects growth in author collaborations with a surge in the JIF. This study recommends that quick retraction is essential to reduce the adverse effects of faulty research.

Indian Research Trends in Digital Humanities: an Analysis

The goal of this study is to identify research trends in India's "Digital Humanities" field. For this study, every kind of Indian research output that has been published and is indexed in the Scopus database has been taken into account. The current quantitative analysis examines a variety of publication-related factors, including growth by year, author patterns, level of collaboration, publication source, subject, and citation, among others. The study examines 35 research projects using a variety of criteria, concluding that interest in digital humanities research is growing in India. The study's conclusions show that the trend of high-quality source journals for research is expanding.

Retention of American Indian and Alaska Native participants in the National Alzheimer's Coordinating Center Uniform Data Set.

The number of American Indian and Alaska Native (AI/AN) elders is expected to double by 2060. Thus it is imperative to retain AI/AN participants in longitudinal research studies to identify novel risk factors and potential targets for intervention for Alzheimer's disease and related dementias in these communities. The National Alzheimer's Coordinating Center houses uniformly collected longitudinal data from the network of National Institute on Aging (NIA)-funded Alzheimer's Disease Research Centers (ADRCs). We used logistic regression to quantify participant retention at 43 ADRCs, comparing self-identified AI/AN participants to non-Hispanic White (NHW) participants, adjusting for potential confounding factors including baseline diagnosis, age, sex, education, and smoking. The odds of AI/AN participant retention at the first follow-up visit were significantly lower than those for NHW participants (adjusted odds ratio [aOR]: 0.599; 95%: 0.46-0.78; p<0.001). These results suggest the need for improved strategies to retain AI/AN participants, perhaps including improved researcher-community relationships and community engagement and education. American Indian and Alaska Native (AI/AN) research participants were retained to the first follow-up appointment at lower rates than non-Hispanic White (NHW) participants. AI/AN participants are retained at lower rates than NHW participants for long-term follow-up. The majority of AI/AN participants were not retained to the second follow-up visit.

Real-World Outcomes with Intensive Chemotherapy in Acute Myeloid Leukemia Patients Deemed “Unfit” for Remission Induction By Landmark Trials' Criteria

Background: Induction mortality rates in acute myeloid leukemia (AML) ranges from 7.1% to 40% across Indian tertiary care centers (Kayal S, ASH 2022) exceeding those in the western countries, possibly due to treatment delay, multidrug resistant infections, and inadequate social support. Furthermore, patients seen in our clinics are not representative of those in landmark clinical trials, as a majority of them would be considered unfit for intensive induction based on the trial criteria. Consequently, these patients are left with treatment options, such as less intensive hypomethylating agents, BCL2 inhibitors, and newer targeted therapies. However, these drugs often remain unfeasible due to high out-of-pocket costs and regulatory approval delays, so a majority of patients receive intensive induction with antibiotics. In this retrospective study, we evaluate the effectiveness and toxicities associated with the utilization of such a strategy in the Indian context. Method: This retrospective study was conducted at a single tertiary care cancer center in India. It included patients aged ≥15 years, with acute myeloid leukemia, who received intensive induction chemotherapy as decided by the multidisciplinary joint clinic between January 01, 2017, and December 31, 2019. Patient data were extracted from the Indian acute leukemia research database [INwARD], which is a prospective registry of multiple centers, maintained and audited by the Clinical Data Management Center [CDMC], Vellore for the Hematology cancer consortium and is compliant with ICH-GCP regulations. Ethical approval was obtained from the institutional ethics committee, and the study was registered in the Clinical Trial Registry - India (CTRI/2020/02/023455). Patients were categorized based on the established criteria for “unfit for intensive chemotherapy” derived from landmark trials (VIALE-A, NCT02203773, VIALE-C), and subsequent analyses were performed. Outcomes assessed included 30-day induction mortality, documented infection at diagnosis (defined as fever with radiological, microbiological, or clinical focus of infection) and fungal infections according to EORTC and MSG classifications. Post-induction bone marrow response was defined as complete response/complete response with incomplete marrow recovery (CR/CRi) with ≤5% BM blasts, platelet count &amp;lt;100 × 10 9/L, and absolute neutrophil count &amp;lt;1.0 × 10 9/L. Kaplan-Meier analyses were conducted to assess event-free survival and overall survival. Results: Among 1326 eligible patients, 385 received intensive chemotherapy during the study period (49 received less intensive therapy, 442 referred outside, 210 on palliative care, 212 lost to follow up and 28 died). Demographic and baseline characteristics are detailed in Table 1. Cytarabine and daunorubicin (98.9%) were the most common first-line treatments. Of the 385 patients receiving intensive chemotherapy, 188 were categorized as unfit according to the study criteria (Refer Table 1). The unfit cohort exhibited higher 30-day induction mortality compared to the fit cohort (20.5% vs. 6%, P&amp;lt;0.0001) with a trend for higher incidence of proven and probable fungal infections (18.4% vs. 11.2%, P=0.054). Complete remission rates (CR+CRi) were lower in the unfit cohort (52.4% vs. 68%, P&amp;lt;0.001), while no difference in documented bloodstream infections was observed (P=0.754). Univariate analysis revealed that induction mortality was most influenced by age&amp;gt;50 (P=0.019), ECOG ≥2 (P=0.002) and infection at diagnosis (P&amp;lt;0.0001). However, upon conducting multivariate analyses, infection at diagnosis emerged as the strongest predictor of induction mortality (OR:2.91, 95%CI, 1.51 to 5.59, P=0.001). The median follow up was 15.7 months (range, 0.2-73.8). The 2-year estimated event-free survival (EFS) and overall survival (OS) of the entire cohort was 42.9% and 69.2% respectively. For the unfit and fit cohort, the 2-year EFS was 42.2% vs 43.9% (P=0.065), and the 2-year OS was 62.5% vs 75.1% (P=0.001) respectively. Conclusion: Unfit patients who received intensive chemotherapy had higher induction mortality and lower overall survival. Furthermore, it underscores the importance of improving accessibility to novel therapies, to provide a safe and viable alternative for nearly half of our AML patient population.

Exploring factors influencing the use of open access resources in India: A novel perspective on Indian researchers

This study investigates the use of OA resources among faculty members and research scholars at IITs in North India and explores the factors influencing their engagement with OA resources. Self-administered questionnaires were distributed to participants from selected departments across four IITs in North India, resulting in 814 respondents. The study’s conceptual framework is based on the Social Exchange Theory (SET) and the Unified Theory of Acceptance and Use of Technology (UTAUT). The findings indicate that while the majority of participants were aware of OA resources, their actual use was limited. Critical determinants for using OA resources were identified, including internet self-efficacy, awareness and attitude toward OA, accessibility, trustworthiness, professional recognition, academic reward, altruism, mandates and culture, and individual traits. Copyright concerns were found to negatively influence OA resource use, while additional time, effort and cost had no significant impact. The study emphasizes the importance of formulating OA policies, promoting awareness and understanding, and addressing copyright concerns to facilitate the effective use of OA resources, thereby benefiting knowledge dissemination and scholarly communication.