Central India Research Articles

Study of Otorhinolaryngological Manifestations in Symptomatic COVID-19-Positive Patients at Tertiary Health Care Hospital: A Cross-sectional Study.

Introduction The coronavirus disease 2019 (COVID-19), also referred to as the 2019 novel coronavirus, is caused by a single-stranded positive-sense RNA virus. This infectious agent spreads through respiratory routes, primarily utilizing aerosols. In our study, we shed light on ear, nose, and throat (ENT) manifestations, which can be considered as prognostic clinical biomarkers to reduce forthcoming complications among such critically ill patients. This makes it feasible for researchers to investigate or fetch early diagnosis in such cases with ease without the use of large, extensive hospital-base setups. Objective To study the otorhinolaryngological (ENT) manifestations in symptomatic COVID-19 patients. Methods From January to December 2021, a cross-sectional observational study was conducted at the Department of ENT of a tertiary care hospital in central India. All eligible symptomatic COVID-19 patients admitted to this institution during the study period were consecutively enrolled. The Institutional Ethics Committee gave its permission for the project. Results Out of the total of 1,375 patients, 78% of the patients diagnosed with COVID exhibited symptoms related to the ENT, while the remaining 22% did not display any ENT manifestations. Anosmia (71.2%), sore throat (55.62%), headache (44.3%), and loss of taste (66.3%) were among the most common ENT symptoms. Conclusion The present study highlights ENT manifestations, which play a crucial role in the early diagnosis of COVID-19 patients, ensuring faster treatment and isolation for better containment of the disease. Symptomatic treatment has shown efficacy, but objective tests are needed to prevent overestimation, understand pathogenesis, and enhance treatment.

Do Anatomical Variations of Sphenoid Sinus Influence Sella Exposure and Residual Disease in Pituitary Surgery? - A Study in an Indian Population.

Introduction Endoscopic transsphenoidal surgery (ETS) is the standard practice in pituitary surgeries. The sellar exposure becomes the main factor which determines the residual disease in ETS. Not many studies can be found in the literature on the influence of anatomical variations of the sphenoid on intraoperative sella exposure. Objective The aim of the current study is to ascertain whether sphenoid sinus variations play a role in sellar exposure and residual tumor volume. Methods This is a prospective study conducted in a south Indian tertiary care center between June 2020 to June 2022, with 21 study participants who were scheduled to have ETS. The relation of preoperative computed tomography (CT) and magnetic resonance imaging (MRI) parameters with the intraoperative area of sellar exposure and residual tumor volume was evaluated. Results Sphenoid sinus dimensions, like presellar width (mean = 1.89 ± 0.51 cm), maximum width (mean = 2.94 ± 1.09 cm), presellar depth (mean = 1.14 ± 0.55 cm), suprasellar depth (mean = 1.08 ± 0.24 cm), infrasellar depth (mean = 2.36 ± 0.92 cm), presellar height (mean = 2.22 ± 0.47 cm), or the 9 internal carotid artery (ICA)-related measures, did not have any correlation with the mean intraoperative area of sellar exposure (0.57 ± 0.28 cm 2 ). Also, the adequacy of sellar exposure did not relate to the residual tumor. Preoperative tumor volume was found to be higher (20.2 [55.3-13.2] cm 3 ) in patients with residual tumor compared with those with no residual tumor (5.9 [6.8-5.2] cm 3 ). Tumor extension had a significant association with the residual tumor volume. Conclusion According to the present study, anatomical variations of the sphenoid sinus do not influence the adequacy of sellar exposure. Further studies need to be undertaken concerning residual tumor volume as well as preoperative tumor volume and extension.

A Randomized Case-Control Study on High-Frequency Chest Wall Oscillator Versus Conventional Chest Physical Therapy in Spinal Cord Injury Subjects

Study Design: This study is a randomized case-control trial. Setting: Indian Spinal Injuries Centre, Vasant Kunj, New Delhi, India. Background: Spinal cord injury (SCI) often results in severe respiratory dysfunction, leading to increased morbidity and mortality. Respiratory complications, including atelectasis and pneumonia, are prevalent and exacerbated by compromised lung function and ineffective cough. CCPT poses risks like hypoxemia and arrhythmias. HFCWO has emerged as a promising alternative, facilitating airway clearance and improving lung function without manual intervention. Despite its efficacy in other conditions, its specific benefits in SCI require further study. Objective: To study the effect of High-Frequency Chest Wall Oscillator versus Conventional Chest Physical Therapy in candidates with Spinal Cord Injury. Methodology: A sample of 78 SCI patients was selected, with 71 completing the study. Patients were divided into Group A (HFCWO) and Group B (CCPT). Baseline vital, clinical, and radiological parameters were recorded. Group A received HFCWO twice daily for 15 minutes over 5 days, while Group B received CCPT that included positioning, percussions on the affected lobe, and mechanical vibration for 5 days as indicated. Suctioning was performed post-intervention in both groups. Parameters were re-evaluated post-treatment and after 5 days by an intensivist. Results: The median (IQR) age of participants was 32 (18 to 60). Wilcoxon signed- rank test was used for intragroup analysis. The intervention group (HFCWO) had a median age of 49, and the control group (CCPT) had a median age of 22.In the HFCWO group, RR significantly decreased and SpO2 significantly increased (p<0.05) from Day 1 to Day 5. No significant changes were observed in HR and MAP. PEEP, FiO2, and ROASSCI significantly decreased (p<0.05). In the CCPT group, RR, HR, and MAP significantly increased (p<0.05), with no significant change in SpO2. PEEP and FiO2 significantly decreased, but ROASSCI did not change. Both groups showed significant improvement in Chest X-ray scores (p<0.05). Conclusion: This study compares High-Frequency Chest Wall Oscillator (HFCWO) with conventional chest physical therapy (CCPT) in spinal cord injury patients. HFCWO showed superior improvements in clinical and radiological parameters, facilitating earlier ventilator weaning. These findings suggest that HFCWO is a more effective alternative to CCPT for airway clearance in intubated SCI patients.

Clinicoradiological, pathological, and surgical outcome in patients with tethered cord syndrome: A prospective study

Background: Tethered cord syndrome (TCS) is a stretch-induced functional disorder of the spinal cord in which the caudal part is anchored by an inelastic structure. It is believed that, if the viscoelasticity of the filum is lost or compromised by either fatty infiltration or abnormal thickening, caudal tension and traction may cause undue stress upon the conus, resulting in TCS. It typically occurs in children, and it is rare in adults. Aims and Objectives: The study was conducted to know the clinicoradiological, pathological, and surgical outcomes in patients with TCS. Materials and Methods: This is a prospective observational study done in the premier institute of central India from May 2022 to April 2024. This study included patients who exhibited clinical and/or radiological features of congenital tethered cords. This encompassed both patients with tethered cord and those with TCS. Patients who failed to give consent and refused to participate in the study were excluded from the study. Results: A total of 30 patients were recruited for the study. The median age of the patients was 6–12 months (range). The gender distribution M:F was 63.3:36.6. Based on 30 cases studied, most of the patients (75%) had improvement in urinary symptoms, 57.1% of patients had improvement in bowel symptoms, 80% of patients had improvement in pain symptoms, 75% had improvement in motor deficit, and 83.3% had improvement in sensory deficit. Conclusion: Our prospective, cross-sectional study aimed at complete detethering of the spinal cord and the nerve roots along with excision of filum terminale and dural reconstruction to maintain adequate cerebrospinal fluid space around the spinal cord to prevent retethering.

Assessment of Bioenergy Potential in Vindhya Plateau, Madhya Pradesh

Evaluating agricultural residue availability is crucial for assessing sustainable biomass energy production. Crop waste, a byproduct of agricultural production, can be used for soil amendment, animal feed, and energy generation. A survey in seven districts of central India (Bhopal, Damoh, Guna, Raisen, Sagar, Sehore, and Vidisha) was conducted to assess the availability of agricultural residue in the Vindhya Plateau, which comprises about 16% of Madhya Pradesh's geographical area. Agricultural residue availability was determined by selecting a crop, gathering data on yield and generated biomass (including surplus), and estimating the bioenergy potential. The cultivable areas in the selected districts have bioenergy potentials of 19.91, 15.19, 7.88, 21.89, 13.71, 15.09, and 17.21 kJ ha-1 for crops like soybean, rice, wheat, gram, and maize, respectively. The total residue potential, surplus residue potential, and bioenergy potential of the Vindhya Plateau were assessed as 6.08 MT, 2.42 MT, and 40 GJ, respectively. Vindhya Plateau's Raisen district offers the highest biomass potential, making it ideal for bioenergy development and fuel production from biomass.

157P Functional progression post Nusinersen therapy in spinal muscular atrophy type 2: a comprehensive 18-month analysis from a South Indian centre

157P Functional progression post Nusinersen therapy in spinal muscular atrophy type 2: a comprehensive 18-month analysis from a South Indian centre

Crafting State-of-the-art Agroforestry for Bundelkhand using Insights from Past

Bundelkhand, a pivotal land area in Central India, is geographically demarcated across the states of Uttar Pradesh and Madhya Pradesh. The 13 districts in both states share similarities in cultural and socio-economic aspects. This paper commences with a descriptive portrayal of the Bundelkhand region, delving into the agricultural scenario, which is highly influenced by rainfall patterns. The region boasts a dominant agrarian rural population, with more than 40% comprising women. Owing to the lower productivity of wheat, farm diversification has been consistently recommended. In this context, agroforestry presents a respite, fostering resilience at the farm level. Agri-silvicultural and silvipastoral systems are typically recommended for this region and are detailed alongside the traditionally prevailing agroforestry practices of the area. This review synthesizes the need for agroforestry adoption for four major reasons and its impact on the Bundelkhand region. Furthermore, it presents the constraints, problems, and motivational factors for adopting agroforestry, ultimately providing directions for the way forward

Prevalence Estimates of Metabolic Syndrome among the General Population of Central India at Public Health Facilities of Ratlam District, Madhya Pradesh

Prevalence Estimates of Metabolic Syndrome among the General Population of Central India at Public Health Facilities of Ratlam District, Madhya Pradesh

Mastalgia and Why It Should Be Evaluated With Imaging in Areas Where Use of Breast Cancer Screening Services are Unsatisfactory.

Mastalgia or breast pain is a very common symptom in women attending breast clinic. The aim of this study was to evaluate whether imaging for mastalgia leads to cancer detection in an area where routine breast cancer screening services are underutilized. This prospective study was performed between 1st March 2021 to 31st January 2023 at a tertiary care academic institution of central India. All patients underwent through clinical examination by a surgeon. Then patients were referred for ultrasound and/or X-ray mammography (MMG) depending on age. Cancer detection rate was calculated. The final cohort consisted of 176 patients with mastalgia and without any abnormality on clinical breast examination. Sixteen patients had mass lesion on radiology and core needle biopsy resulted as infiltrating duct carcinoma in 7 patients and benign phylloides tumor in one patient. Overall case detection rate for cancer was 4%. The breast cancer detection rate in patients presenting with mastalgia was low. However, in the absence of routine mammographic screening in the Indian general population, these would have been missed. Hence, diagnostic assessment for mastalgia is an appropriate strategy in countries where routine screening MMG is lacking.

Analyzing the Trade-Offs between Soil Health Enhancement, Carbon Sequestration, and Productivity in Central India’s Black Soil through Conservation Agriculture

The impact of conservation tillage (CST) practices on soil properties, carbon sequestration and yield sustainability over short, medium, and long durations remain insufficiently understood, especially in semiarid Central India. Therefore, our objective was to investigate the effects and optimal duration of CST adoption for enhancing soil properties, carbon sequestration, and sustainable yields. We conducted a study in farmers’ fields in the Akola district of Central India, where CST had been practised for 4 to 15 years, within a soybean + pigeon pea–chickpea cropping sequence. Our findings revealed significant (p < 0.05) improvements in soil physical properties with short-term CST practices (4 to 6 years), alongside increasing availability of nitrogen and phosphorus, with longer durations of CST implementation (10 to 15 years). The lowest soil organic carbon (SOC) was observed in conventional tillage (CT_y), while all CST practices increased SOC content over CT_y, ranging from 22.2 to 38.4%. Further, experimental soil dominated passive C pools (Cfrac3 + Cfrac4). Consequently, long-term CST practices facilitated positive C sequestration rates, contrasting with negative or minimal sequestration observed in CT_y and short-term CST treatments. However, compared to CST, CT_y demonstrated higher soybean equivalent yields and comparable chickpea equivalent yields mainly due to delayed germinations induced by lower soil temperatures in CST plots. We conclude that integrating site-specific characteristics, management practices, and regional climate conditions into conservation agriculture frameworks maximizes efficacy and ensures sustainable productivity. These findings help optimize agricultural practices considering potential yield losses or minimal changes despite implementing CST.

Satellite-based measurements of temporal and spatial variations in C fluxes of irrigated and rainfed cotton grown in India

The small number of carbon dioxide (CO2) observation networks and the prohibitively high equipment cost restrict the estimation of net ecosystem CO2 exchange (NEE). Satellite-based remote sensing techniques have made it possible to obtain NEE and component carbon (C) fluxes. One-third of the world's cotton area is in India, but the information on NEE is limited. We used the Level 4 Carbon (L4_C) product from the Soil Moisture Active Passive (SMAP) mission to estimate C fluxes based on satellite-derived soil moisture, weather, and vegetation data. For our study (2018-19 to 2020-21), we chose two ecosystems (rainfed central India vs. irrigated northern India). Seasonal variations were observed in C fluxes. Gross primary productivity was the highest during the boll formation phase. This phase was the strongest sink and coincided with the highest CO2 uptake, followed by the flowering and square formation phases. The cotton crop was a C source during the initial vegetative phase and after the boll opening. Overall, the cotton crop was a sink for atmospheric CO2 with an average NEE value of −189.6 g C m−2 under irrigated and −245.6 g C m−2 in rainfed cotton. Higher ecosystem respiration in irrigated cotton resulted in lower C sink strength than rainfed cotton. Our studies indicate that the SMAP L4_C product model estimates can be used to obtain information on C fluxes in real-world situations. Moreover, such satellite-based remote sensing techniques will enable large-scale environmental monitoring with different cropping systems and support policymaking.

Survival Analysis of Triple-Negative Breast Cancer in a Rural Tertiary Care Center of Central India

Survival Analysis of Triple-Negative Breast Cancer in a Rural Tertiary Care Center of Central India

Spectrum of Kikuchi-Fujimoto Disease: A 10-Year Study in a Tertiary Care Centre in South India.

Background Kikuchi-Fujimoto disease (KFD) is a benign lesion of the lymph nodes predominantly seen in younger women and is a condition associated with a good prognosis due to its indolent nature. Since KFD is chiefly a diagnosis of exclusion, it is liable to a higher degree of misdiagnosis. Aim In our study, we attempt to document and analyse the demographic, clinical, and pathological spectrum of cases diagnosed as KFD in a South Indian tertiary care centre over a period of 10 years. Methodology This study was conducted in a retrospective observational manner. Descriptive statistics, including simple frequency and percentage, were used to analyse and summarise the collected data. Results Among the 44 cases obtained, 36 patients were female and eight were males, with an age range of eight to 70 years. The mean age of the affected population was 26 years. Fever was a presenting complaint in 63.6% of cases, and 100% of the cases had lymphadenopathy, chiefly affecting the posterior cervical group of nodes (32/44 cases). Multiple lymph node groups were involved in 22 cases. Most of the nodes were larger than 1 cm in their greatest dimension. On analysis of peripheral smears, 43.2% of patients showed leukopenia. Anti-nuclear antibody (ANA) analysis showed a positive status among two patients, simultaneously establishing the diagnosis of systemic lupus erythematosus (SLE). A history of treated tuberculosis was present in four patients, and one patient had a history of non-compliance with TB treatment. Two patients had recently been diagnosed with TB and were on treatment. The involved nodes were subjected to fine-needle aspiration studies in 13 patients; 12/13 cases showed reactive lymphadenitis, while one case had atypical lymphoid cells. The involved nodes of all the patients were excised and sent for histopathological analysis. The diagnosis of KFD was confirmed on the biopsy. Conclusion In this study, we note the clinical presentations of all the patients diagnosed with KFD and elaborate on the investigations that were employed to verify the diagnosis via exclusion that enabled differentiation of KFD from its close mimickers, which have specific treatment. Keeping this entity in mind is essential in order to prevent overdiagnosis, as most often this condition resolves spontaneously, and in occasional cases, symptomatic treatment is sufficient for its management.

Assessment of Uranium Pollution in Ground Water and Human Health in Balod District, Chhattisgarh

A laser fluorimetric technique was used to measure the amount of uranium present in samples of groundwater from the Balod district, Chhattisgarh, central India. For this purpose, we collected twenty-nine water samples from different villages in the Balod district, Chhattisgarh from September 2022 to June 2023. Here, the concentration of uranium in the sample of water ranges from 0.10 to 66.7(µg/l). A maximum number of samples had uranium contamination levels below the acceptable limit (30 µg/l), except for Siwani village (66.7µg/l), as approved by the WHO. The USEPA recommendations were used to determine the chemical risk ( Non-carcinogenic) and excess lifetime carcinogenic risk (ECR) caused by groundwater consumption. The allowed excess lifetime cancer risk ( ELCR) value of 1.0´10-4was found to be exceeded in a few water samples by the risk of cancer resulting from drinking water. The LADD value of 18 % and HQ value of 24% of the water sample exceed the permissible limit indicating a high risk of chemical poisoning. In this analysis, we found that the area's uranium's chemical toxicity may be the cause of non-carcinogenic health problems, but eventually, there is no Carcinogenic (radiological) risk to people.

Feasibility, Safety, and Factors Predicting Completion of CROSS Protocol–Based Neoadjuvant Chemoradiotherapy for Esophageal Squamous Carcinoma: Experience from an Indian Tertiary Care Cancer Center

Background Neoadjuvant chemoradiotherapy (NACRT) using the ChemoRadiotherapy for Oesophageal cancer followed by Surgery Study (CROSS) protocol has improved esophageal cancer outcomes. This study reports the real-world experience of the CROSS regimen for esophageal squamous cell carcinoma (ESCC) regarding its feasibility, safety, and predictors of treatment completion from an Indian tertiary center. Methodology A retrospective review was conducted for patients with ESCC receiving CROSS (radiation dose: 41.4 Gy) or a modified CROSS (mCROSS; radiation dose: 45 Gy) protocol NACRT between 2015 and 2022. We studied the treatment tolerability, factors predicting NACRT completion, and the effect of completion of its chemotherapy component on the pathological outcomes. Results Of the109 patients (68.8% males; mean age, 56 ± 9 years; Charlson's comorbidity index [CCI] >2, 19.3%; stage III–IVA, 58%; mean tumor length, 5.5 ± 2.1cm; CROSS, 70.6%; mCROSS, 29.4%), all except 4 completed radiotherapy but only 58 (53.2%) patients completed ≥4 cycles of chemotherapy. Forty-nine patients belonged to the “extended” CROSS trial inclusion criteria. Among the 60 patients who fulfilled the CROSS inclusion criteria, only 51.7% were able to complete ≥4 chemotherapy cycles. The commonest reason for noncompletion of chemotherapy was the occurrence of neutropenia (60.8%). Pretreatment hemoglobin (≥12 vs. <12 g%; odds ratio [OR]: 2.76; 95% confidence interval [CI]: 1.10–6.96; p = 0.031), a low CCI (≤2 vs. >2; OR: 2.98; 95% CI: 1.02–8.73; p = 0.047), and radiation therapy techniques (conformal vs. conventional; OR: 3.29; 95% CI: 1.14–9.50; p = 0.028) were associated with completion of chemotherapy (≥4 cycles). Although there was a trend toward improved R0 resection (95.7 vs. 91.4%), reduced node positivity (17.0 vs. 31.4%), and a high pCR (57.4 vs. 48.6%) in patients completing chemotherapy (≥4 cycles) compared with those not completing chemotherapy (<4 cycles), these differences were statistically nonsignificant. Conclusion In this study, ESCC patients receiving the CROSS protocol NACRT could complete their radiotherapy component, but a significant proportion exhibited poor chemotherapy tolerance. Neutropenia was a major factor limiting chemotherapy delivery, but anemia, high CCI, and conventional radiation techniques were also associated with noncompletion of chemotherapy. The omission of a few chemotherapy cycles had no significant effect on the pathological response; however, its impact on cancer survival requires further evaluation.

In vitro toxicity assessment of bioavailable iron in coal varieties of Central India

Introduction Information on bioavailable Iron (BAI) content in respirable coal dust (RCD) is crucial to address occupational health and safety, especially in preventing coal workers’ pneumoconiosis (CWP). Materials and methods In the present study, we determined BAI concentrations in seventy-seven coal samples collected from ten coal mining regions of Central India. The cytotoxic potential of BAI-RCD was established invitro by using alveolar epithelial (A549) and macrophage (U937) cell lines. The oxidative/antioxidant status, inflammations, and genotoxicity attributed to BAI-RCD exposure were evaluated and correlated with CWP pathophysiology. Results The mean BAI concentrations in the coal samples (n = 77) range from (275 to 9065 mg kg-1) and showed wide variability. Both cell lines were exposed to low (275 mg kg-1), moderate (4650 mg kg-1), and high (9065 mg kg-1) BAI-RCD samples showed significant (p < 0.001) cytotoxicity in a dose-dependent manner (low < moderate < high) compared to the control. After BAI-RCD treatment, both cell lines showed a decrease in antioxidant stress measures (SOD, CAT, and GSH) and a significant (p < 0.001) increase in oxidative stress parameters (NADPH, MPO, LPO, and PC). Furthermore, these cell line models demonstrated a statistically significant (p < 0.001) dose-dependent increase in cytokines (TGF-β1, IL-1β, TNF-α, MCP-1, and IL-6 cytokines) and oxidative DNA damage marker (8-OH-dG). Conclusion Results indicated that the central India coals (even at low BAI content) may be accountable for inflammatory responses and cytotoxicity. Hence, BAI can be important characteristic to establish safety standards for coal dust exposure before active mining.

Understanding tropical cyclone persistence over land: A case study of Cyclone Gulab

Abstract Tropical Cyclone (TC) Gulab originated in the Bay of Bengal during the post-monsoon season of 2021. Following an unusual westward trajectory, TC Gulab made landfall on the east coast of India, traversed central India, and reintensified over the Arabian Sea into TC Shaheen. This study employed an online Eulerian water vapor tracer (WVT) tool embedded within the Weather Research and Forecasting (WRF) model to investigate the role of land in terms of soil moisture and Land Use Land Cover (LULC) in persistance of TC Gulab over central India. We quantified the contributions of sub-regions and dominant LULC types within the Indian subcontinent to the precipitation associated with TC Gulab. Our findings indicate that evapotranspiration across the entire Indian subcontinent contributed approximately 30% to the post-landfall precipitation associated with TC Gulab. The highest contribution originated from the northwestern region, followed by the northeast. Croplands, the dominant LULC type, were the primary contributors, followed by forests. Despite changing the dominant land cover from cropland to forest, the low-pressure system persisted over land while altering the spatial patterns of precipitation. Sensitivity experiments demonstrated a linear decrease in precipitation originating from land with decreasing soil moisture (SM). Notably, there is a disproportionate decline in total precipitation with decreasing SM. Further analysis separating atmospheric vapor sources into land and ocean contributions using WVT revealed a compensatory mechanism. The contribution of oceanic vapor to atmospheric vapor over land increased when SM decreased due to increase in the latent heat over ocean. However, the total atmospheric vapor remained low, ultimately leading to a lower total precipitation. Although SM plays a role, our results highlight the importance of oceanic and atmospheric processes in determining TC persistence over land. This study offers valuable insights into the dynamics of land-atmosphere interactions during low-pressure systems of TCs.

A Study of Hearing Acuity and the Health of the External Auditory Canal Among Earphone Users in Central India.

Background and objective The pervasive use of earphones has raised concerns about its potential impact on hearing acuity and the health of the external auditory canal (EAC). This study aimed to investigate these effects in a sample of individuals in Central India to better understand the associated risks. Materials and methods This observational cross-sectional study was conducted in the Department of Otorhinolaryngology, Acharya Vinoba Bhave Rural Hospital, SawangiWardha. A total of 130 participants aged 15-35 years were divided into two groups: 65 earphone users and 65 non-earphone users. The data collection involved medical histories, clinical examinations, and audiometric testing, including pure-tone audiometry (PTA), impedance audiometry, and otoacoustic emissions (OAE). Participants completed a questionnaire on earphone usage, and EAC health was assessed via physical examinations and photographic documentation. Statistical analyses included descriptive and inferential statistics, with significance set at p<0.05. Results Among earphone users, 45 (69.23%) exhibited hearing loss compared to 11 (16.92%) in non-users (p<0.00001). Noise-canceling earphones were associated with fewer cases of hearing loss (6/45, 13.33%) than non-noise-canceling types (39/45, 86.67%) (p<0.00001). EAC issues were more prevalent in earphone users, with 39 (60%) showing normal conditions versus 52 (80%) in non-users. Impactions of wax, otomycosis, and otitis externa were observed more frequently among earphone users. Conclusions The study highlights a significant association between earphone use and increased risk of hearing loss and EAC issues. Noise-canceling earphones may offer some protective benefits. These findings underscore the need for raising awareness and implementing preventive measures to mitigate potential risks associated with prolonged earphone use.

Morphometric indices assessment: Implications for active tectonics in the upper Narmada Basin, central India

During the Palaeoproterozoic era, the Northern and Southern cratonic blocks of the Indian Plate came together and amalgamated. Farther, facilitated by the East-West trending central Tectonic Suture Zone, characterized by the Son-Narmada Fault/Lineament (SNF/L) and Central Shear (CIS) Zone, has long intrigued researchers due to its implications for active tectonics, particularly in the Narmada basin. In this study, we employ geomorphic and morphotectonic indices to elucidate the neotectonic activity in the Upper Narmada basin (UNB) of central India. Utilizing SRTM-DEM data, we analyze morphometric and morphotectonic parameters to shed light on the development of drainage patterns and active tectonics within the basin. Our findings reveal a pronounced influence of tectonics on basin evolution, as evidenced by high bifurcation ratios indicative of intense tectonic activity and elevated ruggedness values suggestive of heightened erosion susceptibility. The predominant ENE-WSW orientation of the Son Narmada South Fault (SNSF) and Son Narmada North Fault (SNNF), aligned with major lineament trends, exerts control over the Narmada River drainage network. Additionally, the high value (<50) of the asymmetric factor reveals the significant tectonic influence on the Upper Narmada basin, while the transverse asymmetric factor and stream length index values further corroborate the basin's susceptibility to active tectonics. Notably, the abrupt elevation changes (200–600 m asl) reflected by Dhuandhar, Kapildhara and other falls along the course of Narmada provide compelling evidence of neotectonic activity. Thus, we assert that morphotectonic analyses employing Digital Elevation Maps, satellite imagery, and SRTM-DEM data represent an efficacious approach for investigating complex basin morphotectonics.

Assessment of Soil Enzyme Activity in Soybean Fields under Long-Term Fertilization and Manuring Practices

The experiment carried out in this field study was between at theAICRP Research Farm in the outward-bound farm of the College of Agriculture, Indore. Indore is a small city in the western part of Madhya Pradesh, Central India, situated on the Malwa Plateau. An experiment was conducted with three replications by using different combination of N, P levels and crop residues in RBD design. Experiment field was medium to black soil with pH of 7.63 and medium in organic carbon 0.58%. The soil was low in available nitrogen (208.0 kgha-1) medium in available phosphorus (21.0 kgha-1) and high in potassium (585 kg ha-1) and divided into gross plot size of 10 x 7.2 m2 and a net plot size of 9 x 6.4 m2, respectively. During crop harvest four different depths were used to gather the soil samples: 0–10, 10–20, 20–30, and 30–40 cm. All the collected samples are examined separated for Dehydrogenase, Urease enzyme, Acid &amp; alkaline phosphate, Arysulphatase activity. The finding showed that maximum soil DHA, Urease, Acid &amp; alkaline phosphate, Arysulphataseactivitywas observed with the application of treatment T6 treatment (FYM 6 t ha-1 + N20 P13.