North-central India is underlain by three northeast-trending paleo-topographic ridges of Precambrian Indian basement, bounded by lithospheric-scale basement faults. The Pokhara Fault defines the eastern edge of the Faizabad paleo-topographic ridge, which exposes the Archean Bundelkhand Craton. Near Panna, Madhya Pradesh, the Pokhara Fault coincides with a monocline developed in the Proterozoic Vindhyan Supergroup rocks along the Bundelkhand cratonic margin. Fluvial morphology of basins along the monocline, as well as a deeply incised abandoned meander preserved where the Ken River flows through the monocline, are investigated using longitudinal stream profiles and other geomorphic data along the length of the monocline to assess potential linkages with active basement fault reactivation.Normalized steepness indices in analyzed channel profiles along the monocline increase significantly downstream, with some channels exhibiting convex, over-steepened segments. Normalized steepness indices, knickpoint elevations, and incision depths are on average much higher in streams along the southwest segment of the monocline compared to streams along the northeast segment. Most channel profiles exhibit a knickpoint with slope-break morphology. The obtained longitudinal channel profiles exhibit characteristics of a fluvial system in a transient state subjected to an increase in rock uplift that intensifies to the southwest over a reactivated basement fault. Using previously published relationships between erosion rates and channel steepness, we conservatively estimate the onset age of monocline growth to be Plio-Quaternary. Fluvial geomorphic features preserved near Panna also suggest that the Ken River is an antecedent river. The incised meander feature near the crest of the monocline appears to be the abandoned river valley of a former Ken River course that was orphaned during the evolution of the landscape by what is now the present-day Ken River.Our study supports growing evidence that Indian basement faults such as the Pokhara Fault are long-lived and have recorded multiple periods of reactivation. Recent fluvial modification in the Panna region demonstrates that Indian basement faults are also active on the south side of the Ganga Basin, far south of the Himalayan deformation front, and may be linked to intraplate seismicity and active tectonic modification of the landscape.