Drought, as a natural and intricate climatic phenomenon, poses challenges with implications for both natural ecosystems and socioeconomic conditions. Evaluating the characteristics of drought is a significant endeavor aimed at mitigating its impact on society and individuals. This research paper explores the integration of the Standardized Precipitation Evapotranspiration Index (SPEI) and machine learning techniques for an assessment of drought characteristics in the Middle Ganga Plain, a crucial agro-climatic region in India. The study focuses on evaluating the frequency, intensity, magnitude, and recurrence interval of drought events. Various drought models, including Random Forest (RF), Artificial Neural Networks (ANN), and an ensemble model combining ANN and RF, were employed to analyze and predict drought patterns at different temporal scales (3-month, 6-month, and 12-month). The performance of these models was rigorously validated using key metrics such as precision, accuracy, proportion incorrectly classified, over-all area under the curve (AUC), mean absolute error (MAE), and root mean square error (RMSE). Furthermore, the research extends its application to delineating drought vulnerability zones by establishing demarcations for high and very high drought vulnerability areas for each model and temporal scale. Results indicate that the south-western part of the middle Ganga plain falls under the highly drought-vulnerable zone, which averagely covers 40% of the study region. The core and buffer regions of drought vulnerability have also been identified. The south-western part of the study area is identified as the core region of drought. Ground verification of the drought-vulnerable area has been done by using soil moisture meter. Validation metrics show that the ensemble model of ANN and RF exhibits the highest accuracy across all temporal scales. This research's findings can be applied to improve drought preparedness and water resource management in the Middle Ganga Plain. By identifying high-risk drought zones and utilizing accurate prediction models, policymakers and farmers can implement targeted mitigation strategies. This approach could enhance agricultural resilience, protect livelihoods, and optimize water allocation in this vital agro-climatic region.