Self-propelled synthetic particles have attracted scientific interest due to their potential applications as nanomotors in drug delivery and their insight into bacterial taxis. Research on their dynamics has focused on understanding phoresis and self-phoresis in catalytic Janus particles at both the nano- and microscale. This study explores the combined effects of self-diffusiophoresis and self-thermophoresis induced by exothermic chemical reactions on the surface of active particles moving in non-electrolyte media. We examine how these phoretic phenomena interact, influenced by the coupling between chemical reactions, heat generation, and the concentration and temperature fields at the particle interface. Using a theoretical framework based on the induction of surface tension gradients at the particle interface, we analyze the phoretic dynamics, quantifying parameters such as effective diffusivities, transport coefficients, and, most importantly, phoretic coefficients. Our findings provide insights into the conditions that dictate coupled or independent phoretic behaviors, with implications for drug delivery and nanomotor applications, enabling customized transport processes at the nanoscale.