The purpose of this study was to determine if selected cephalometric changes noted in groups of growing patients with Class II, Division 1 malocclusions treated with the Fränkel function regulator (FR-2), the edgewise technique, and the light-wire (Begg) mechanism were different and characteristic of a specific technique. To this end, the changes in the SNA, SNB, N-S-Gn, and the SN-GoGn angles, face height (N-M), the anterior movement of pogonion, and the annualized mandibular growth increment (AR-Gn) in a group of patients treated with the FR-2 were compared to the changes noted in similar groups of patients treated by the edgewise technique and the light-wire mechanism. The methods used to compare the groups were an analysis of variance and a discriminant analysis. A reduction in the SNA angle was observed in all groups. It was −0.37 ° with light wire treatment, −0.60 ° with Fränkel appliance use, and −1.47 ° with edgewise therapy. The SNB angle increased in all three groups, ranging from 0.29 ° in the edgewise group to 0.56 ° in the Fränkel group. In the light-wire group it was 0.34 °. The N-S-Gn angle in the Fränkel group remained essentially the same (0.06 °), while in the light-wire and edgewise groups it increased 0.81 ° and 0.82 °. The SN-GoGn angle opened slightly in all groups, ranging from a low of 0.46 ° with Fränkel therapy to 0.58 ° with edgewise treatment to 1.25 ° with the use of the light-wire appliance. Face height (N-M) increased in all groups: 5.86 mm in the Fränkel patients, 6.12 mm in the light-wire group, and 7.38 mm in the edgewise group. Pogonion moved anteriorly 1.62 mm in the light-wire group, 2.14 mm in the edgewise group, and 2.60 mm in the patients treated with the Fränkel appliance. Finally, the annualized increase in mandibular length (Ar-Gn) was similar for all three groups: 2.70 mm (edgewise), 2.90 mm (light-wire), and 3.10 (Fränkel). There were no statistically significant differences in any of the variables when the changes occurring with all three techniques were compared.