Increased Tooth Mobility Research Articles

Treatment of periodontal disease in beagles with lodoxamide ethyl, an inhibitor of mast cell release.

The effect of lodoxamide ethyl, a mast cell release inhibitor on the progression of chronic periodontal disease in beagles was examined. Twelve adult female beagles with naturally occurring periodontitis were studied. Following a six‐month pretreatment baseline period, six dogs were given 20 mg/kg lodoxamide ethyl orally for a twelve‐month treatment period. In addition, at the beginning of the treatment period one‐half’ mouth in each dog was treated with periodontal flap surgery. Thus, the experimental design allowed a comparison of the progression of periodontitis about premolar teeth in a pretreatment period with progression of periodontitis in a treatment period in which one of the following treatment protocols was used: no treatment, teeth treated with periodontal flap surgery, teeth treated with lodoxamide ethyl administration, and teeth treated with lodoxamide ethyl administration plus periodontal flap surgery.In the systemically untreated dogs the rate of alveolar bone loss increased in the treatment period, compared to the baseline pretreatment period about both teeth not treated locally and teeth treated with flap surgery. In contrast, the rate of alveolar bone loss was significantly reduced in the treatment period in those dogs administered lodoxamide ethyl daily. Lodoxamide ethyl administration combined with flap surgery was more effective than lodoxamide ethyl alone. Tooth mobility significantly increased in those dogs administered lodoxamide.The data indicate that administration of an orally active mast cell release inhibitor can decrease the rate of alveolar bone loss which occurs in beagle periodontitis. However, the clinical usefulness of this pharmacologic agent is not clear due to the increased tooth mobility which occurred in this study. Since the principle effect of lodoxamide ethyl is believed to be on mast cell degranulation, a role for mast cells in beagle alveolar bone loss is implied.

An unusual cause of increased tooth mobility during orthodontic treatment; a report of two cases: I. D. BrownJ. Dent., pp. 161–164, December, 1972

An unusual cause of increased tooth mobility during orthodontic treatment; a report of two cases: I. D. BrownJ. Dent., pp. 161–164, December, 1972

Development, etiology and diagnosis of increased tooth mobility and of traumatic occlusion.

Development, etiology and diagnosis of increased tooth mobility and of traumatic occlusion.

Effect of nutritional hyperparathyroidism on experimental periodontitis in the dog.

abstract – The purpose of the present investigation was to induce osteopenia of the alveolar process by feeding dogs a calcium‐deficient, phosphorus‐rich diet, and to determine whether dogs suffering from nutritional secondary hyperparathyroidism (NSH) developed: (1) increased tooth mobility, (2) gingivitis and (3) periodontitis with marginal alveolar bone resorption in plaque‐free areas and in areas where plaque and calculus were allowed to accumulate. The experiments were performed on six, 12‐month‐old Beagle dogs. During an experimental period of 18 months, four dogs (test group) were fed a low calcium, high phosphorus diet of a soft consistency. The controls were fed an adequate but soft diet. The teeth of the right jaws were regularly subjected to thorough cleaning. NSH and osteopenia of the alveolar bone were induced in the test dogs. Osteopenia, however, did not result in an increased tooth mobility or gingivitis in the absence of plaque. In areas where dental deposits were allowed to accumulate, pathologic pockets gradually developed in both test and control animals, but the degree of attachment loss was the same in both groups.

An unusual cause of increased tooth mobility during orthodontic treatment: A report of 2 cases

Elastic bands are commonly used in orthodontics to move teeth. Two cases are presented illustrating the danger arising when these elastics are able to slip around the crown into the gingival sulcus. Case 1 suggests that elastics should never be used by themselves but always in conjunction with orthodontic appliances. Case 2 shows that even if such a recommendation is acted upon then errors by the patient can still lead to disaster.